The global market for cardiovascular surgical devices used in the operating room is worth an estimated $31 billion in 2010. By 2015, this market will be valued at nearly $48 billion, a compound annual growth rate (CAGR) of 8.7%.

Despite significant growth in interventional cardiac surgery procedures, the traditional cardiac surgical device market is expected to expand faster, primarily driven by the growth in cardioprosthetics such as ventricular assist devices. This sector is worth an estimated $7 billion in 2010 and is expected to increase at a 10.9% compound annual growth rate (CAGR) to reach $12 billion in 2015.

The second fastest area of growth is in cardiac rhythm management devices, particularly for the treatment of atrial fibrillation (AF). This sector is valued at $11 billion in 2010 and is expected to be worth $18 billion in 2015, a compound annual growth rate (CAGR) of 10.2%.

INTRODUCTION

STUDY GOALS AND OBJECTIVES

The goal of this study is to explore the different factors affecting cardiovascular surgery and the manufacture of cardiovascular devices. Cardiac surgery is on the rise globally, with macroeconomic factors such as aging populations; increased obesity, poor nutrition, and other heart-health stressors; and the technological maturity of devices that make sophisticated treatments feasible for patients in previously inaccessible populations.

Whether through disease, congenital defects, or generalized degradation of cardiological function over time, cardiovascular diseases are increasing dramatically, substantiating the need for continued growth of cardiovascular surgery.

REASONS FOR DOING THIS STUDY

According to statistics from the American Medical Association (AMA), more than 80 million people suffer from some form of heart disease. While cardiovascular surgery has long been practiced, recent innovations such as minimally invasive procedures, “beating heart” surgeries, cardiac rhythm management (CRM), and other procedural improvements have become treatments that create fewer side effects for patients and less time spent in post-surgical recovery.

Newer cardiovascular devices and procedures play a large part in enhancing the quality of life for an increasingly elderly population, as well as populations with poor cardiac function and other heart-related diseases. The ability of government-run health agencies and private insurers to cope with the increasing need for cardiovascular procedures and the skyrocketing costs involved have lead agencies and insurers alike to consider their payments surrounding necessary medical procedures and, consequently, cardiovascular surgical procedures.

This report will identify areas of growth within the cardiovascular surgical equipment market and identify companies offering innovative equipment relating to cardiovascular devices. Growth will be projected on manufacturers’ net revenues, unless otherwise indicated.

This report is designed to achieve the following objectives: 

Describe the trends and developments for each type of cardiovascular surgical technology and how each is meant to meet marketplace needs.
Analyze market and driving forces to project market size for the technologies and pinpoint target applications.
Examine the cardiovascular surgical business in terms of companies and their position in the market.

The report is designed to appeal to many different readers, including venture capitalists interested in exploring commercialization opportunities, marketing, and management individuals within the industry, and even the novice reader, who desires to understand how market pressures and technology interact in this industry.

SCOPE OF REPORT

The scope of this study encompasses multiple technologies and procedures related to cardiovascular surgical devices. The study focuses on several different types and categories of cardiovascular surgery involving traditional, interventional, and CRM devices, categorized logically so that comparisons can be made within diagnostic and procedural groups as well as across the cardiovascular surgical device industry as a whole.

BCC analyzes the industry on a worldwide basis from market, product, and technology perspectives. Regulations and reimbursement issues and patents issued from 2005 to 2010 are also examined to identify consumer safety, product INTRODUCTION, and product safety regulatory issues for stakeholders and potential stakeholders in this industry.

The report examines the cardiovascular surgery equipment industry in general, the types of technology currently in use as well as future applications, and regulatory influences. The industry structure section discusses the most active manufacturers with regard to relative market share, marketing strengths, and forces that promote or hamper growth of technologies. The technology sections detail historical, current, and projected (2010 through 2015) market values.

METHODOLOGY

BCC presents an analysis across the entire cardiovascular surgical device market based on reported revenue dollars and units shipped as reported to the Securities and Exchange Commission (SEC) and/or other governmental agencies, as well as company information such as annual reports and product/financial news releases.

We also analyze data gathered from the United States Patent Office (USPTO) databases. Technological and demographic information is gathered from industry sources, governmental sources, and published news reports.

INFORMATION SOURCES

BCC conducted primary and secondary research to develop this report. Sources included companies in the cardiovascular device market and supply industry, public documents, SEC filings, corporate white papers, and other technical documentation for U.S. and international companies directly involved in manufacturing and distributing of cardiovascular devices and related equipment. The report excludes resellers and retailers, focusing rather on the primary companies responsible for the development of the underlying technology.

Where precise information was not available, a consensus was made using reasonable assumptions and estimates based on historical data.

Table Of Contents

Chapter- 1: INTRODUCTION

STUDY GOALS AND OBJECTIVES 1
REASONS FOR DOING THIS STUDY 1
SCOPE OF REPORT 2
METHODOLOGY 2
INFORMATION SOURCES 3
ANALYST CREDENTIALS 3
RELATED BCC PUBLICATIONS 3
BCC ONLINE SERVICES 3
DISCLAIMER 4

Chapter-2: SUMMARY

SUMMARY TABLE GLOBAL MARKET FOR CARDIOVASCULAR SURGICAL DEVICES, THROUGH 2015 ($ MILLIONS) 5
SUMMARY FIGURE CARDIOVASCULAR SURGICAL DEVICES BY TYPE, 2010 AND 2015 (%) 6

Chapter-3: OVERVIEW OF THE INDUSTRY

GLOBAL INCIDENCES OF CARDIAC DISEASE 7
CARDIAC DISEASE IN DEVELOPED COUNTRIES 7
CARDIAC DISEASE IN DEVELOPING COUNTRIES 8
HISTORY OF CARDIOVASCULAR SURGERY 8
INDUSTRY CONSOLIDATION 9
TABLE 1 SELECTED ACQUISITIONS AND MERGERS, 2001-2010 ($ MILLIONS) 9
RISKS ASSOCIATED WITH CARDIAC SURGERY 9
TYPES OF SURGERIES 10
TRADITIONAL CARDIAC SURGERY 10
OPEN HEART SURGERY 10
Objectives 10
Risks 11
TABLE 2 LEADING MANUFACTURERS OF OPEN HEART SURGICAL DEVICES 11
CARDIOPULMONARY BYPASS GRAFT SURGERY 11
Objectives 11
Risks 12
TABLE 3 LEADING MANUFACTURERS OF CABG SURGICAL DEVICES 12
BEATING HEART SURGERY (OFF-PUMP BYPASS SURGERY) 12
Objectives 12
Risks 12
TABLE 4 LEADING MANUFACTURERS OF BEATING HEART SURGICAL DEVICES 13
TRANSMYOCARDIAL REVASCULARIZATION 13
Objectives 13
Risks 13
TABLE 5  LEADING MANUFACTURERS OF TMR SYSTEMS 13
CARDIOPROSTHETICS 14
Objectives 14
Risks 14
TABLE 6 LEADING MANUFACTURERS OF CARDIOPROSTHETICS SURGICAL DEVICES 14
TABLE 6 (CONTINUED) 15
FIGURE 1 GLOBAL MARKET LEADERS IN TRADITIONAL CARDIAC SURGICAL DEVICES, 2009 (%) 15
FIGURE 1 (CONTINUED) 16
INTERVENTIONAL CARDIAC SURGERY 16
MIDCAB 16
Objectives 17
Risks 17
TABLE 7 LEADING MANUFACTURERS OF INTERVENTIONAL CARDIAC SURGERY DEVICES 17
TABLE 7 (CONTINUED) 18
ENDOSCOPIC CARDIOVASCULAR SURGERY 18
Objectives 18
Risks 18
PLAQUE REMOVAL SURGERY 18
Angioplasty 19
Objectives 19
Risks 19
TABLE 8 LEADING MANUFACTURERS OF ANGIOPLASTY DEVICES 19
Atherectomy 20
Objectives 20
Risks 20
TABLE 9 LEADING MANUFACTURERS OF PLAQUE REMOVAL DEVICES 20
Laser Angioplasty 20
Objective 21
Risks 21
Stent Procedure 21
Objectives 21
Risk 22
TABLE 10 LEADING MANUFACTURERS OF CARDIAC STENTS 22
FIGURE 2 MARKET SHARES HELD BY LEADERS IN DES, 2009 (%) 23
Cardiomyoplasty 23
Objectives 23
Risks 24
Robotic-assisted Heart Surgery 24
Objectives 24
Risks 25
Vascular Surgery 25
Objective 25
Risks 25
MARKET LEADERS IN INTERVENTIONAL CARDIAC SURGERY 25
FIGURE 3 GLOBAL MARKET LEADERS IN INTERVENTIONAL CARDIAC SURGICAL DEVICES, 2009 (%) 26
CRM SURGERY 26
Cardiac Ablation for Rhythm Management 27
TABLE 11 LEADING MANUFACTURERS OF CARDIAC ABLATION DEVICES TO PROMOTE CRM 27
Pacemakers 27
Objective 27
Risks 28
TABLE 12 LEADING MANUFACTURERS OF CARDIAC PACEMAKERS 28
Defibrillators 28
Objective 28
Risk 29
TABLE 13 LEADING MANUFACTURERS OF CARDIAC DEFIBRILLATORS 29
Catheters 29
Objective 29
Risks 29
TABLE 14 LEADING MANUFACTURERS OF CRM CATHETERS 30
Market Leaders 30
FIGURE 4 GLOBAL MARKET LEADERS IN CARDIAC RHYTHM MANAGEMENT SURGICAL DEVICES, 2009 (%) 31

Chapter-4: GLOBAL IMPLICATIONS OF CARDIOVASCULAR DISEASE AND CARDIOVASCULAR SURGERY

CORONARY HEART DISEASE IN DEVELOPED NATIONS 32
CORONARY HEART DISEASE IN DEVELOPING COUNTRIES 33
PRIMARY RISK FACTORS IN CVD 33
ECONOMIC CONSEQUENCES OF CVD 33
TABLE 15 LEADING CAUSES OF HEART FAILURE, 2002-2006 (%) 34
U.S. MARKET 34
POPULATION 34
TABLE 16 HEART DISEASE IN THE U.S., 2006 (MILLIONS) 35
LEADING CARDIOVASCULAR SURGICAL CENTERS 35
TABLE 17 LEADING CARDIOVASCULAR SURGERY CENTERS, U.S., 2010 35
EUROPEAN MARKET 35
TYPES OF CARDIOVASCULAR SURGERIES PERFORMED 36
ECONOMIC BURDEN OF CVD IN THE EU 36
LEADING CARDIOVASCULAR SURGICAL CENTERS 36
TABLE 18 LEADING CARDIOVASCULAR SURGERY CENTERS IN BRITAIN, 2006 36
THE EU 27 AND EASTERN EUROPE 37
COST AND VALUE EVALUATION 37
JAPAN 37
LEADING CARDIOVASCULAR SURGICAL CENTERS 38
TABLE 19 LEADING CARDIOVASCULAR SURGERY CENTERS IN JAPAN, 2006 38
CHINA 38
TABLE 20 LEADING CARDIOVASCULAR SURGERY CENTERS IN CHINA, 2003 39
INDIA 39
LEADING CARDIOVASCULAR SURGICAL CENTERS 39
TABLE 21 LEADING CARDIOVASCULAR SURGERY CENTERS IN INDIA, 2010 40
REST OF THE WORLD 40
IMPLICATIONS FOR CARDIOVASCULAR SURGERY 40
TABLE 22 SELECTED WORLDWIDE CORONARY PROCEDURES, 2008 (PER 100,000 POPULATION) 41
FIGURE 5 PERCENTAGE OF MARKET BY GEOGRAPHICAL AREA, 2010 (%) 42
IMPLICATIONS FOR TRADITIONAL CARDIAC SURGERY 42
Market Strengths 43
Market Weaknesses 43
Opportunities 43
Threats 43
IMPLICATIONS FOR INTERVENTIONAL CARDIAC SURGERY 43
Strengths 44
Weaknesses 44
Opportunities 44
Threats 44
IMPLICATIONS FOR CRM SURGERY 44
Strengths 45
Weaknesses 45
Opportunities 45
Threats 45

Chapter-5: GLOBAL MARKET FOR TRADITIONAL CARDIAC SURGERY DEVICES

TABLE 23 GLOBAL VALUE OF TRADITIONAL CARDIAC SURGERY DEVICES, THROUGH 2015 ($ MILLIONS) 46
OPEN HEART SURGERY 47
BYPASS SURGERY 47
TABLE 24 PROJECTED GLOBAL MARKET FOR OPEN HEART AND CABG-RELATED SURGICAL DEVICES, THROUGH 2015 ($ MILLIONS) 48
BEATING HEART SURGERY 48
BEATING HEART SURGERY (CONTINUED) 49
TABLE 25 GLOBAL REVENUES FROM BEATING HEART SURGICAL DEVICES, THROUGH 2015 ($ MILLIONS) 50
NEW DEVICES 50
TRANSMYOCARDIAL REVASCULARIZATION 50
TABLE 26 GLOBAL MARKET FOR TMR DEVICES, THROUGH 2015 ($ MILLIONS) 51
CARDIOPROSTHETIC SURGERY 51
VAD MARKET 52
TABLE 27 GLOBAL MARKET FOR CARDIOPROSTHETICS DEVICES, THROUGH 2015 ($ MILLIONS) 53
TOTAL ARTIFICIAL HEARTS 53
AbioMed 53
SynCardia 53
TABLE 28 GLOBAL MARKET FOR TOTAL ARTIFICIAL HEARTS, THROUGH 2015 ($ MILLIONS) 54
VENTRICULAR ASSIST DEVICES 54
Regeneration Instead of Replacement 54
TABLE 29 GLOBAL MARKET FOR VADS, THROUGH 2015 ($ MILLIONS) 55
VAD as Destination Therapy 55
HEART VALVES 56
Advantages/Disadvantages of Mechanical, Biological, and Homograft Heart Valves 56
Mechanical 56
Biological/Tissue 56
Homograft 57
The Market for Valves 57
TABLE 30 GLOBAL HEART VALVE MARKET, THROUGH 2015 ($ MILLIONS) 57
TABLE 31 LEADING HEART VALVE SUPPLIERS, 2009 ($ MILLIONS) 58
HEART VALVE MARKET IN THE FUTURE 58

Chapter-6: INTERVENTIONAL CARDIAC SURGERY DEVICES

INTERVENTIONAL CARDIAC SURGERY DEVICES 59
TABLE 32 GLOBAL MARKET FOR INTERVENTIONAL CARDIAC SURGERY DEVICES, THROUGH 2015 ($ MILLIONS) 60
PERCUTANEOUS CORONARY INTERVENTION 60
TABLE 33 GLOBAL MARKET FOR PCI CATHETERS, THROUGH 2015 ($ MILLIONS) 61
DRAWBACK OF PCI 61
LEADING MANUFACTURERS 61
FIGURE 6 MARKET LEADERS IN PCI CATHETER SALES BY COMPANY, 2009 (%) 62
STENTS 62
TABLE 34 PROJECTED GLOBAL MARKET FOR STENTS, THROUGH 2015 ($ MILLIONS) 63
FIGURE 7 GLOBAL MARKET SHARES FOR STENTS BY REGION, 2009 (%) 64
MARKET COMPETITION 64
VALVULOPLASTY 65
VALVE REPLACEMENT VIA CATHETER 65
TRANSCATHETER AORTIC VALVES 65
CARDIAC ABLATION 66
THROMBECTOMY 66
CRYOABLATION 66
RF ABLATION 67
ABLATION DEVICE MANUFACTURERS 67
TABLE 35 GLOBAL MARKET FOR CARDIAC ABLATION DEVICES, THROUGH 2015 ($ MILLIONS) 67
CARDIOVASCULAR ROBOTIC SURGERY 67
TABLE 36 GLOBAL MARKET FOR CARDIOVASCULAR ROBOTIC SURGERY DEVICES, THROUGH 2015 ($ MILLIONS) 68

Chapter-7: GLOBAL MARKET FOR CARDIAC RHYTHM MANAGEMENT DEVICES

ARRHYTHMIAS 69
CAUSES OF ARRHYTHMIAS 69
ATRIAL FIBRILLATION 69
AF TREATMENTS 69
LEFT ATRIAL APPENDAGE OCCLUSION 70
Watchman Occluder 70
Amplatzer Device 71
CRM GLOBAL MARKET 71
TABLE 37 PROJECTED GLOBAL MARKET FOR CARDIAC RHYTHM MANAGEMENT DEVICES, THROUGH 2015 ($ MILLIONS) 72
PACEMAKERS 72
TABLE 38 PROJECTED GLOBAL MARKET FOR PACEMAKERS, THROUGH 2015 ($ MILLIONS) 73
FIGURE 8 MARKET POSITION FOR LEADING MANUFACTURERS OF PACEMAKERS (%) 73
DEFIBRILLATORS 74
TABLE 39 PROJECTED GLOBAL MARKET FOR IMPLANTABLE DEFIBRILLATORS, THROUGH 2015 ($ MILLIONS) 74
FIGURE 9 MARKET SHARE OF LEADING MANUFACTURERS OF IMPLANTABLE DEFIBRILLATORS, 2010 74
FIGURE 9 (CONTINUED) 75
ELECTROPHYSIOLOGY CATHETERS 75
TABLE 40 PROJECTED GLOBAL VALUE OF OTHER CRM DEVICES, 2010-2015 ($ MILLIONS) 76
ABLATION CATHETERS FOR TREATING AF 76

Chapter-8: ONGOING DEVELOPMENT OF CARDIOVASCULAR DEVICES/TREATMENTS

TRADITIONAL CARDIAC SURGERY 77
HEART-LUNG DEVICES 77
Maquet 77
LVAD 78
TABLE 41 LEFT VENTRICULAR ASSIST DEVICES IN DEVELOPMENT 78
OTHER CARDIAC ASSIST DEVICES IN DEVELOPMENT 78
Sunshine Heart 79
INTERVENTIONAL CARDIAC SURGERY 79
STENTS 79
Conor MedSystems 79
Biotronik/Abbott Vascular 80
OrbusNeich 80
Abbott Vascular 80
Medtronic 81
NEOANGIOGENESIS 81
HEART VALVES 82
Abbott Vascular 82
University of Michigan 82
National Heart, Lung, and Blood Institute Clinical Trials 82
CARDIAC SUPPORT DEVICES 83
Passive Support Systems 83
Acorn Cardiovascular 83
Paracor Medical 83
University of Leeds 84
CARDIAC RHYTHM MANAGEMENT 84
CYBERKNIFE 84
HEMODYNAMIC MONITORS 85
CARDIAC RESYNCHRONIZATION THERAPY DEFIBRILLATORS 85

Chapter-9: REIMBURSEMENT AND REGULATION ISSUES

REIMBURSEMENT 86
UNITED STATES 86
CMS Proposed Reimbursement Rates for 2011 87
CMS Reimbursement for ICDs 87
Proposed “Bundling” of Services 88
EUROPEAN UNION 89
CHINA 89
Centralized Tendering Proposals 90
JAPAN 90
REGULATIONS 91
UNITED STATES 91
Permission to Distribute a Device 92
FDA Export Requirements 93
Newer Regulations 93
Reclassification of PTCA Devices 94
U.S. Cardiovascular Surgical Device Recalls: 2005-2010 94
TABLE 42 U.S. CARDIOVASCULAR SURGICAL DEVICE RECALLS, 2005-2009 94
DIFFERENCES IN EUROPEAN AND U.S. REGULATIONS 95
EUROPEAN UNION 95
CHINA 96
Additional Incentives for Local Manufacturers 96
JAPAN 97
Costs of Gaining Approval in Japan 97

Chapter-10: PATENT ANALYSIS

CARDIAC RHYTHM MANAGEMENT 98
PACEMAKERS 98
TABLE 43 U.S. PATENTS ISSUED FOR CARDIAC PACEMAKER EQUIPMENT, JUNE 2006-AUGUST 2010 98
TABLE 43 (CONTINUED) 99
DEFIBRILLATORS 99
TABLE 44 U.S. PATENTS ISSUED FOR CARDIAC DEFIBRILLATOR EQUIPMENT, APRIL 2009-AUGUST 2010 100
STENTS 101
TABLE 45 U.S. PATENTS ISSUED FOR CARDIAC STENT EQUIPMENT, JUNE 2007-JULY 2010 101
CATHETERS 102
TABLE 46 U.S. PATENTS ISSUED FOR CARDIAC CATHETER EQUIPMENT, DECEMBER 2005-AUGUST 2010 102
TABLE 46 (CONTINUED) 103
TABLE 46 (CONTINUED) 104
ELECTROPHYSIOLOGY EQUIPMENT 104
TABLE 47 U.S. PATENTS ISSUED FOR ELECTROPHYSIOLOGY EQUIPMENT, OCTOBER 2006-JULY 2010 104
TABLE 47 (CONTINUED) 105
CARDIAC VALVES 105
TABLE 48 U.S. PATENTS ISSUED FOR CARDIAC VALVE SURGERY, FEBRUARY 2007-AUGUST 2010 105
TABLE 48 (CONTINUED) 106
OTHER CARDIAC SURGERY EQUIPMENT 106
TABLE 49 U.S. PATENTS ISSUED FOR OTHER CARDIAC SURGERY EQUIPMENT, JANUARY 2005-AUGUST 2010 106
TABLE 49 (CONTINUED) 107
TABLE 49 (CONTINUED) 108
TABLE 49 (CONTINUED) 109
BY YEAR 109
TABLE 50 U.S. CARDIOVASCULAR SURGICAL DEVICES BY YEAR, JANUARY 2005-AUGUST 2010 (NUMBER) 110
FIGURE 10 U.S. CARDIOVASCULAR SURGICAL DEVICES BY TYPE, 2005-2010 (%) 110
FIGURE 10 (CONTINUED) 111
BY ASSIGNEE 111
TABLE 51 U.S. CARDIOVASCULAR SURGICAL DEVICE PATENTS BY ASSIGNEE (NUMBER) 111
TABLE 51 (CONTINUED) 112

Chapter-11: COMPANY DIRECTORY

ABBOTT CARDIOVASCULAR 113
BUSINESS OVERVIEW 113
FINANCIALS 113
PRODUCTS 114
TABLE 52 ABBOTT VASCULAR CARDIOVASCULAR SURGICAL PRODUCTS 114
ABIOMED, INC. 115
BUSINESS OVERVIEW 115
FINANCIALS 115
PRODUCTS 115
TABLE 53 ABIOMED CARDIOVASCULAR SURGICAL PRODUCTS 116
ABLATION FRONTIERS (MEDTRONIC) 116
BUSINESS OVERVIEW 116
FINANCIALS 116
PRODUCTS 117
TABLE 54 ABLATION FRONTIERS CARDIOVASCULAR SURGICAL PRODUCTS 117
ANGIODYNAMICS, INC. 117
BUSINESS OVERVIEW 117
FINANCIALS 117
PRODUCTS 118
TABLE 55 ANGIODYNAMICS CARDIOVASCULAR CATHETER PRODUCTS 118
ARROW INTERNATIONAL (TELEFLEX) 118
BUSINESS OVERVIEW 118
FINANCIALS 118
PRODUCTS 119
TABLE 56 ARROW INTERNATIONAL CARDIOVASCULAR CATHETER PRODUCTS 119
BECTON DICKINSON AND CO. 119
BUSINESS OVERVIEW 119
FINANCIALS 119
PRODUCTS 120
TABLE 57 BECTON DICKINSON CARDIOVASCULAR SURGICAL PRODUCTS 120
BERLIN HEART AG 120
BERLIN HEART U.S. OFFICE 120
BUSINESS OVERVIEW 120
FINANCIALS 121
PRODUCTS 121
TABLE 58 BERLIN HEART CARDIOVASCULAR SURGICAL PRODUCTS 121
BIOCARDIA, INC. 121
BUSINESS OVERVIEW 121
FINANCIALS 122
PRODUCTS 122
TABLE 59 BIOCARDIA CARDIOVASCULAR SURGICAL PRODUCTS 122
BIOSENSE WEBSTER, INC. 122
BUSINESS OVERVIEW 122
FINANCIALS 123
PRODUCTS 123
TABLE 60 BIOSENSE WEBSTER CARDIOVASCULAR SURGICAL PRODUCTS 123
BIOTRONIK GMBH 124
BUSINESS OVERVIEW 124
FINANCIALS 124
PRODUCTS 124
TABLE 61 BIOTRONIK CARDIOVASCULAR SURGICAL PRODUCTS 125
BLUE MEDIAL DEVICES 125
BUSINESS OVERVIEW 125
FINANCIALS 125
PRODUCTS 125
TABLE 62 BLUE MEDICAL CARDIOVASCULAR SURGICAL PRODUCTS 126
BOSTON SCIENTIFIC CORP. 126
BUSINESS OVERVIEW 126
FINANCIALS 127
PRODUCTS 127
TABLE 63 BOSTON SCIENTIFIC CARDIOVASCULAR SURGICAL PRODUCTS 128
B. BRAUN MELSUNGEN AG 129
BUSINESS OVERVIEW 129
FINANCIALS 129
PRODUCTS 129
TABLE 64 B. BRAUN CARDIOVASCULAR CATHETER PRODUCTS 129
C.R. BARD, INC. 130
BUSINESS OVERVIEW 130
FINANCIALS 130
PRODUCTS 130
TABLE 65 C.R. BARD CARDIOVASCULAR CATHETER PRODUCTS 131
CARDIAC ASSIST, INC. 131
BUSINESS OVERVIEW 131
FINANCIALS 132
PRODUCTS 132
TABLE 66 CARDIACASSIST CARDIOVASCULAR PRODUCTS 132
CARDIMA, INC. 132
BUSINESS OVERVIEW 132
FINANCIALS 132
PRODUCTS 133
TABLE 67 CARDIMA CARDIOVASCULAR PRODUCTS 133
CARDIOGENESIS CORP. 133
BUSINESS OVERVIEW 133
FINANCIALS 133
PRODUCTS 134
TABLE 68 CARDIOGENESIS CARDIOVASCULAR PRODUCTS 134
COOK MEDICAL 134
BUSINESS OVERVIEW 134
FINANCIALS 135
PRODUCTS 135
TABLE 69 COOK MEDICAL CARDIOVASCULAR CATHETER PRODUCTS 135
CORDIS CORP. 136
BUSINESS OVERVIEW 136
FINANCIALS 136
PRODUCTS 136
TABLE 70 CORDIS CARDIOVASCULAR SURGERY PRODUCTS 137
CRYOLIFE, INC. 137
BUSINESS OVERVIEW 137
FINANCIAL 138
PRODUCT 138
TABLE 71 CRYOLIFE CARDIOVASCULAR SURGERY PRODUCTS 138
EDWARDS LIFESCIENCE CORP. 139
BUSINESS OVERVIEW 139
FINANCIALS 139
PRODUCTS 140
TABLE 72 EDWARDS LIFESCIENCES CARDIOVASCULAR PRODUCTS 140
HEARTWARE INTERNATIONAL, INC. 140
BUSINESS OVERVIEW 140
FINANCIALS 141
PRODUCTS 141
TABLE 73 HEARTWARE CARDIOVASCULAR PRODUCTS 141
INTUITIVE SURGICAL 141
BUSINESS OVERVIEW 141
FINANCIALS 142
PRODUCTS 142
TABLE 74 INTUITIVE SURGICAL CARDIOVASCULAR PRODUCTS 143
JARVIK HEART, INC. 143
BUSINESS OVERVIEW 143
FINANCIALS 143
PRODUCTS 143
TABLE 75 JARVIK HEART CARDIOVASCULAR PRODUCTS 144
MAQUET CARDIOVASCULAR (DATASCOPE) 144
BUSINESS OVERVIEW 144
FINANCIALS 144
PRODUCTS 145
TABLE 76 MAQUET CARDIOVASCULAR PRODUCTS 145
MEDTRONIC 145
BUSINESS OVERVIEW 145
FINANCIALS 146
PRODUCTS 146
TABLE 77 MEDTRONIC CARDIOVASCULAR SURGICAL PRODUCTS 146
TABLE 77 (CONTINUED) 147
MERIT MEDICAL SYSTEMS, INC. 147
BUSINESS OVERVIEW 147
FINANCIALS 148
PRODUCTS 148
TABLE 78 MERIT MEDICAL CARDIOVASCULAR SURGICAL PRODUCTS 148
MICROMED TECHNOLOGY, INC. 148
BUSINESS OVERVIEW 148
FINANCIALS 148
PRODUCTS 149
TABLE 79 MICROMED CARDIOVASCULAR SURGICAL PRODUCTS 149
NMT MEDICAL 149
BUSINESS OVERVIEW 149
FINANCIALS 149
PRODUCTS 150
TABLE 80 NMT CARDIOVASCULAR SURGICAL PRODUCTS 150
NUMED, INC. 150
BUSINESS OVERVIEW 150
FINANCIALS 150
PRODUCTS 151
TABLE 81 NUMED CARDIOVASCULAR SURGICAL PRODUCTS 151
ORBUSNEICH 151
BUSINESS OVERVIEW 151
FINANCIALS 152
PRODUCTS 152
TABLE 82 ORBUSNEICH CARDIOVASCULAR SURGICAL PRODUCTS 152
ON-X LIFE TECHNOLGIES, INC. 153
TABLE 83 ON-X LIFE TECHNOLOGIES CARDIOVASCULAR SURGICAL PRODUCTS 153
PLC MEDICAL SYSTEMS 153
BUSINESS OVERVIEW 153
FINANCIALS 154
PRODUCTS 154
TABLE 84 PLC MEDICAL SYSTEMS TMR SURGICAL SYSTEMS 154
SORIN GROUP, SPA 154
BUSINESS OVERVIEW 155
FINANCIALS 155
PRODUCTS 156
TABLE 85 SORIN GROUP CARDIOVASCULAR SURGICAL PRODUCTS 156
SPECTRANETICS 156
BUSINESS OVERVIEW 156
FINANCIALS 157
PRODUCTS 157
TABLE 86 SPECTRANETICS CARDIOVASCULAR SURGICAL PRODUCTS 157
ST. JUDE MEDICAL 157
BUSINESS OVERVIEW 157
FINANCIALS 158
PRODUCTS 158
TABLE 87 ST. JUDE MEDICAL CARDIOVASCULAR SURGICAL PRODUCTS 159
SYNCARDIA SYSTEMS, INC. 160
BUSINESS OVERVIEW 160
FINANCIALS 160
PRODUCTS 160
TABLE 88 SYNCARDIA CARDIOVASCULAR SURGICAL PRODUCTS 160
TERUMO MEDICAL CORP. 160
BUSINESS OVERVIEW 161
FINANCIALS 161
PRODUCTS 161
TABLE 89 TERUMO CARDIOVASCULAR SURGICAL PRODUCTS 161
TABLE 89 (CONTINUED) 162
THORATEC LABORATORIES 162
BUSINESS OVERVIEW 162
FINANCIAL INFORMATION 162
PRODUCTS 163
TABLE 90 THORATEC CARDIOVASCULAR SURGICAL PRODUCTS 163
TRANSMEDICS, INC. 163
BUSINESS OVERVIEW 163
FINANCIALS 164
PRODUCTS 164
TABLE 91 TRANSMEDICS CARDIOVASCULAR SURGICAL PRODUCTS 164
WORLDHEART CORP. 164
BUSINESS OVERVIEW 164
FINANCIAL INFORMATION 164
PRODUCTS 164
TABLE 92 WORLDHEART CARDIOVASCULAR SURGICAL PRODUCTS 165

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