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  4. > Wearable Infusion Systems

Wearable Infusion Systems

  • September 2015
  • -
  • Greystone Research Associates

Summary

The increasing number of drugs that must be infused is creating a new class of drug delivery devices – devices that can deliver therapeutic drugs in volumes up to 10 mL and higher to ambulatory patients. Wearable subcutaneous infusion systems are targeting the growing need for administering biologicals – a segment that includes monoclonal antibodies, immune modulators and blood factors – that are indicated for chronic conditions. These devices distinguish themselves from syringes and injectors by delivering drug volumes in excess of 1-2 mL for durations that are measured in minutes rather than seconds. Several products in this device class have already reached the market, and recent agreements between device suppliers and pharma companies validate the market need that wearable infusion systems address. We expect wearable infusion systems to achieve and sustain double digit unit growth through the end of the decade.

What You Will Learn

- What wearable infusion systems are currently marketed or in development, who are the suppliers, and what are the device specifics?
- What are the therapeutic markets being targeted by wearable infusion systems?
- What are the essential design factors, material selection issues, technologies and market development issues for wearable infusion systems?
- What are the major factors that will drive wearable infusion systems demand?
- How are wearable infusion systems currently aligned with various drug classes and therapeutic markets?
- What is the addressable market for wearable infusion systems?
- What is the expected impact of wearable infusion systems on drug delivery markets?
- Who are the significant players in this segment? What are their strategies? Who are their alliance partners?

Table Of Contents

Wearable Infusion Systems
Executive SummaryInjectable/Infusible Market Segment DynamicsDrug Development Trends
Drug Delivery Device Evolution
The Trend toward Patient Self-Administration
Enabling TechnologyWearable Infusion Systems - Design Factors
Volumes and Viscosities
Primary Packaging
Injection Methodology
Patient Interface
Injection Technology
Piston
Rotary Pump
Expandable Inner Chamber
Expandable Power Supply

Wearable Infusion Systems - Commercial Devices

OEM Devices
Electronic Disposable
Electronic Semi-disposable
Mechanical Disposable

Captive Devices
Electronic Disposable

Single Product Devices
Neulasta On-body Injector (Amgen)

Wearable Infusions Systems - Near-Term Drug Products

Capricor
CSL Behring
Roche
scPharmaceuticals
Ferring
SteadyMed

Wearable Infusion Therapeutics - The Addressable Market

Inflammatory Autoimmune Diseases
Blood Disorders
Cardiovascular
Neurology
Oncology
Metabolic Diseases
Multiple Sclerosis
Reproductive Health
Upper Respiratory Diseases

Market Factors

Self-Administration and Patient Compliance
Regulatory Guidance and Product Approvals
Drug Product Differentiation/Marketability

Company Profiles

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