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Ophthalmic Devices: Technologies and Global Markets

  • September 2015
  • -
  • BCC Research
  • -
  • 163 pages

This BCC Research report provides a detailed analysis of the recent advances in ophthalmic medical devices and its potential impact on the medical device industry; it also examines the market factors and identifies the market potential through 2019.

REPORT HIGHLIGHTS

The global market for ophthalmic devices reached $16.8 billion and nearly $17.7 billion in 2013 and 2014, respectively. This market is forecasted to grow at a compound annual growth rate (CAGR) of 4.6% to reach $22.1 billion in 2019.

This report provides:

• A comprehensive analysis of the ophthalmic device market by reviewing recent advances in diagnostic, surgical and implantation devices that can be used to treat prevalent eye conditions
• Analyses of global market trends, with data from 2013 and 2014, and projections of CAGRs through 2019.
• Breakdowns of the market by device, application, and region.
• Analysis of the recent advances in ophthalmic medical devices and their potential impact on the medical device industry.
• Evaluation of the mareket's dynamics, specifically growth drivers, restraints, and opportunities.
• Profiles of major players in the industry.

SCOPE OF REPORT

This report on ophthalmic devices provides a brief description of the current status of the industry and recent developments. The report analyzes the market trends, and identifies key medical and geographical challenges and rising opportunities in the developed and developing world. Finally, it will provide insights into new developments into ophthalmic and surgical devices that help to improve diagnosis and enhance the treatment of cataracts, glaucoma, refractory and retinal disorders.

Table Of Contents

Ophthalmic Devices: Technologies and Global Markets
CHAPTER 1 INTRODUCTION 2
STUDY GOALS AND OBJECTIVES 2
REASONS FOR DOING THE REPORT 2
SCOPE OF REPORT 3
INTENDED AUDIENCE 3
METHODOLOGY AND INFORMATION SOURCES 3
ANALYSTS' CREDENTIALS 3
RELATED BCC RESEARCH REPORTS 3
BCC RESEARCH WEBSITE 4
DISCLAIMER 4
CHAPTER 2 SUMMARY 6
SUMMARY TABLE GLOBAL OPHTHALMIC DEVICE MARKET BY REGION, THROUGH
2019 ($ MILLIONS) 7
SUMMARY FIGURE GLOBAL OPHTHALMIC DEVICE MARKET BY REGION, 2013-2019
($ MILLIONS) 7
CHAPTER 3 INTRODUCTION 10
FIGURE 1 STRUCTURE OF THE EYE 10
EYE CONDITIONS AND THE ADDRESSABLE POPULATION 11
CATARACTS 11
Cataract Prevalence 11
FIGURE 2 PREVALENCE OF CATARACTS IN THE UNITED STATES, 2000-2050
(MILLIONS) 11
Cataract Treatment 12
GLAUCOMA 12
Prevalence of Glaucoma 13
FIGURE 3 PREVALENCE OF GLAUCOMA IN THE UNITED STATES, 2000-2050
(MILLIONS) 14
Treatment and Monitoring 15
New Surgical Glaucoma Treatments 15
DIABETIC RETINOPATHY 16
Prevalence of Diabetic Retinopathy 17
TABLE 1 PREVALENCE OF DIABETIC RETINOPATHY BY REGION (%) 17
Treatment and Monitoring 18
AGE-RELATED MACULAR DEGENERATION 19
Prevalence of AMD 19
FIGURE 4 PREVALENCE OF AGE-RELATED MACULAR DEGENERATION IN THE
UNITED STATES, 2000-2050 (MILLIONS) 20
Diagnosis and Treatment of AMD 20
REFRACTIVE DISORDERS 21
Prevalence of Refractive Disorders 21
FIGURE 5 PREVALENCE OF MYOPIA AND HYPEROPIC IN THE UNITED STATES,
2000-2050 (MILLIONS) 22
Diagnosis and Treatment of Refractive Disorders 23
CHAPTER 4 THE GLOBAL MARKET 25
TABLE 2 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE, THROUGH
2014 ($ MILLIONS) 25
FIGURE 6 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE, 2014 (%) 25
THE GLOBAL MARKET BY PRODUCT TYPE 26
CONTACT LENSES 26
TABLE 3 GLOBAL CONTACT LENS MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 27
FIGURE 7 GLOBAL CONTACT LENS MARKET BY REGION, 2014 (%) 27
CATARACT SURGERY PRODUCTS 28
TABLE 4 GLOBAL CATARACT SURGERY DEVICE MARKET BY REGION, THROUGH
2019 ($ MILLIONS) 28
FIGURE 8 GLOBAL CATARACT SURGERY DEVICES MARKET BY REGION, 2014 (%) 28
OTHER SURGICAL PRODUCTS 29
FIGURE 9 GLOBAL OTHER SURGERY MARKET BY PRODUCT TYPE, 2014 (%) 30
DIAGNOSTIC PRODUCTS 31
THE GLOBAL MARKET BY GEOGRAPHIC REGION 31
TABLE 5 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY REGION, THROUGH 2019
($ MILLIONS) 31
FIGURE 10 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY REGION, 2014 (%) 31
UNITED STATES 32
TABLE 6 U.S. OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE, THROUGH
2019 ($ MILLIONS) 32
FIGURE 11 UNITED STATES OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE,
2014 (%) 33
INTERNATIONAL MARKET 34
TABLE 7 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE. THROUGH
2019* ($ MILLIONS) 34
FIGURE 12 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE, 2014*
(%) 34
EUROPEAN MARKET 35
TABLE 8 EUROPEAN OPHTHALMIC DEVICE MARKET BY COUNTRY, THROUGH 2019
($ MILLIONS) 36
FIGURE 13 EUROPEAN OPHTHALMIC DEVICE MARKET BY COUNTRY, 2014 (%) 36
ASIA-PACIFIC MARKET 37
TABLE 9 ASIA-PACIFIC OPHTHALMIC DEVICE MARKET BY COUNTRY, THROUGH
2019 ($ MILLIONS) 37
FIGURE 14 ASIA-PACIFIC OPHTHALMIC DEVICE MARKET BY COUNTRY, 2014 (%) 37
COMPETITIVE ENVIRONMENT 38
FIGURE 15 GLOBAL OPHTHALMOLOGY DEVICE MARKET SHARE BY TOP SIX
COMPANIES, 2014 (%) 39
TABLE 10 GLOBAL OPTHALMOLOGY DEVICE MARKET BY LEADING
MANUFACTURERS, 2010-2014 ($ MILLIONS/%) 40
FIGURE 16 GLOBAL CONTACT LENS MARKET SHARE BY COMPANY, 2014 (%) 41
FIGURE 17 GLOBAL CATARACT SURGERY MARKET SHARE BY COMPANY, 2014 (%) 42
FIGURE 18 GLOBAL OTHER SURGERY AND DIAGNOSTICS MARKET SHARE BY
COMPANY, 2014 (%) 43
CHAPTER 5 RECENT ADVANCES IN OPHTHALMIC DEVICES 45
RECENT ADVANCES IN CATARACT SURGERY DEVICES 45
INTRAOCULAR LENS 45
RECENT PRODUCT INTRODUCTIONS 46
Abbott Medical Optics' Technis IOLs 46
TECNIS Symfony Extended Range of Vision 46
TECNIS Toric 47
iTec Preloaded Delivery System 47
AcuFocus' IC-8 IOL 47
AcrySof IQ ReSTOR +3.0 D IOL 47
AcrySof IQ Aspheric IOL and the UltraSert Pre-loaded Delivery System 48
AcrySof IQ PanOptix 48
AcrySof Toric IOLs 48
Bausch and Lomb's TRULIGN Toric IOL 49
Bausch and Lomb's INCISE Microincision IOL 50
BLIS Injector System and enVista IOL 50
Carl Zeiss Meditec's IOLS 50
Oculentis' LENTIS Mplus 51
PhysIOL's FineVision Toric 51
Rayner Intraocular Lenses' IOLs 52
CATARACT SURGERY PRODUCTS 52
RECENT PRODUCT INTRODUCTIONS 53
Alcon's Cataract Refractive Suite 53
Alcon's ORA System with VerifEye Technology 54
Carl Zeiss Medite's ZEISS Cataract Suite 54
PHACOEMULSIFICATION SYSTEMS 55
Abbott's Compact Intuitiv System 55
Alcon's Centurion Vision System 55
Bausch and Lomb's Stellaris and Stellaris PC Systems 56
Carl Zeiss' VISALIS 500 with Advanced Power Modulation 56
Nidek's CV-9000R 57
OTHER CATARACT SURGERY PRODUCTS 57
Haag-Streit's LENSTAR LS900 System 57
Haag-Streit's EyeSuite IOL 58
Nidek's AL-Scan Optical Biometer 58
FEMTOSECOND LASER-ASSISTED CATARACT SURGERY 59
Abbott Medical Optics' Catalys Precision Laser System 60
Alcon's LenSx 60
Bausch and Lomb's VICTUS Femtosecond Laser Platform 60
Bausch and Lomb's ZeroPhaco I/A Hand Piece 61
LENSAR'S LENSAR Laser System 61
RECENT ADVANCES IN OTHER SURGICAL DEVICES 62
AGE-RELATED MACULAR DEGENERATION TREATMENTS 62
Ellex Medical Lasers' 2RT (Retinal Rejuvenation Therapy) 62
Clinical Study Results 63
TREATMENT OF CLINICALLY-SIGNIFICANT MACULAR EDEMA 63
Oraya Therapeutics' Oraya Therapy 64
Clinical Study Results 64
TREATMENT OF CHOROIDAL METASTASES 65
VisionCare Ophthalmic Technologies' Implantable Miniature
Telescope (by Dr. Isaac Lipshitz) 66
Clinical Study Results 67
GLAUCOMA TREATMENT PRODUCTS 67
SELECTIVE LASER TRABECULOPLASTY FOR GLAUCOMA 68
Lumenis' Selective Laser Trabeculoplasty for Glaucoma 68
Clinical Studies 69
Laser in Glaucoma and Ocular Hypertension (LiGHT) Study 69
Ellex Medical Lazers' SLT Products 70
Quantel Medical's Optimis Fusion 70
Quantel Medical's Optimis Fusion 70
OTHER TECHNOLOGIES 71
Aquesys' XEN Gel Stent 71
EyeTechCare's EYEOP-PACK 71
Ellex Medical Laser's Cannauloplasty Products 72
Glaukos Corp.'s iStent Trabecular Micro-Bypass Stent 72
Iridex's Cyclo G6 Laser System 73
NeoMedix' Trabectome 74
iSTAR Medical's STARflo Glaucoma Drainage Device 74
Transcend Medical's CyPass Glaucoma Micro-Stent 75
LASER PHOTOCOAGULATION SYSTEMS 75
NEW PRODUCT INTRODUCTIONS 76
Ellex Medical Lasers Ultra Q Reflex System 76
Ellex Medical Lasers' Rapide Pattern Scanning Photocoagulator 77
Lumenis' Array LaserLink 77
Nidek's GYC-500 Vixi Green Scan Laser Photocoagulator 78
Topcon's PASCAL Laser Systems 78
Quantel Medical's Vitra PDT Photodynamic Therapy Laser Platform 79
Quantel Medical's Vitra Multispot Laser System 80
Quantel Medical's Optimis Fusion 80
REFRACTIVE SURGERY PRODUCTS 80
TYPES OF REFRACTIVE SURGERY 81
TABLE 11 REFRACTIVE SURGERY PRODUCTS 82
Photo-Refractive Keratectomy (PRK) 82
LASIK Surgery 83
LASIK FDA Safety Review 84
Abbott's LASIK Products 84
Alcon's Wavelight Excimer Laser System 85
Alcon and Topography-Guided LASIK 85
Bausch and Lomb's TECHNOLAS TENEO 317 Excimer Laser 85
Carl Zeiss' MEL 90 Excimer Laser 86
Carl Zeiss' SMILE Procedure 86
REFRACTIVE SURGERY IMPLANTS 87
AcuFocu's KAMRA inlay 87
AcuTarget HD 88
STAAR Surgical's Implantable Collamer Lenses 88
RECENT ADVANCES IN OPHTHALMIC DIAGNOSTIC DEVICES 89
DIAGNOSTIC DEVICES 89
NEW PRODUCT INTRODUCTIONS 90
Abbott's iDesign Dx Systems 90
Abbott's iDesign Advanced WaveScan Studio System 90
CARL ZEISS MEDITEC'S DIAGNOSTIC PRODUCTS 91
Glaucoma Diagnostic Products 91
FORUM Data Management System 91
VISUPLAN500 Non-Contact Tonometer 92
VISUSCREEN 100/500 and VISUPHOR 500 Acuity Chart and Digital
Phoropter 92
Zeiss Slit Lamps 93
I-Optic's Cassini Corneal Topography System 93
COLOR LED TOPOGRAPHY 94
Nidek's MP-3 Microperimeter 94
Nidek's PM-700 Pupillary Distance Meter 94
Rapid Pathogen Screening's InflammaDry Test 94
TOPCON's Refractometry Products 95
IMAGING SYSTEMS 96
ADVANCED TECHNOLOGIES 96
Optical Coherence Tomography 96
Scanning Laser Ophthalmoscopy 97
Heidelberg Engineering's Spectralis Imaging System 97
RECENTLY INTRODUCED OCT PRODUCTS 99
Bausch and Lomb's Swept Source OCT Imaging System 99
Carl Zeiss Meditec's' CIRRUS HD-OCT 5000 100
Carl Zeiss' IOLMaster 700 with SWEPT Source Biometry 100
Carl Zeiss Medic's OPMI LUMERA 700 and RESCAN 700 101
Optovue's SD-OCT Technology Products 101
Nidek's Retina Scan Duo OCT 102
Nidek's RS-3000 Advance 102
Topcon's Swept Source DRI OCT Triton 103
Optovue's OCT Angiography Technology 103
RECENTLY INTRODUCED LASER OPHTHALMOSCOPY PRODUCTS 104
i-Optics' EASYSCAN 104
RETINAL IMAGING CAMERAS 105
Carl Zeiss Meditec's VISUSCOUT 100 105
Optovue's iCam Non-Mydriatic Fundus Camera 105
TopCon's Retinal Imaging Products 106
IMAGEnet 5 Digital Imaging System 106
RECENT ADVANCES IN CONTACT LENSES 107
DEVELOPMENTS IN CONTACT LENS MATERIALS 108
RECENT PRODUCT INTRODUCTIONS 108
TABLE 12 CONTACT LENS PRODUCT LAUNCHES, APRIL, 2013-JUNE, 2015 109
Bausch and Lomb's PureVision 2 Multi-Focal Fit Guide 110
Antitrust Class Action Lawsuits against Contact Lens
Manufacturers 110
CHAPTER 6 PIPELINE DEVICES 113
CATARACT SURGERY PRODUCTS IN DEVELOPMENT 113
TABLE 13 CATARACT SURGERY PRODUCTS IN LATE-STAGE DEVELOPMENT 113
ALCON'S ACRYSOF TORIC IOLS 114
MORCHER'S XTRA FOCUS IOL 114
BAUSCH and LOMB'S CIRLE SURGICAL NAVIGATION SYSTEM 114
IOLS IN EARLY DEVELOPMENT 115
POWERVISION FLUIDVISION ACCOMMODATING IOL 115
CALHOUN VISION'S LIGHT ADJUSTABLE LENS 115
CLARVISTA MEDICAL'S HARMONI IOL 116
ELENZA'S SAPPHIRE IOL 116
REFRACTIVE SURGERY PRODUCTS IN DEVELOPMENT 117
TABLE 14 REFRACTIVE SURGERY PRODUCTS IN LATE-STAGE DEVELOPMENT 117
ALCON AND TOPOGRAPHY-GUIDED LASIK 118
BAUSCH and LOMB'S SUPRACOR PROCEDURE 118
CARL ZEISS' SMILE PROCEDURE 118
STAAR SURGICAL'S TORIC IMPLANTABLE COLLAMER LENSES 119
IMPLANTS TO TREAT PRESBYOPIA 120
TABLE 15 PRESBYOPIA IMPLANTS IN DEVELOPMENT 120
REVISION OPTICS' RAINDROP NEAR VISION INLAY 120
PRESBIA'S FLEXIVUE MICROLENS 121
DELIVERY DEVICES 122
Refocus Group's VisAbility Implant System 122
Neoptics' Icolens 123
GLAUCOMA PRODUCTS IN DEVELOPMENT 124
TABLE 16 GLAUCOMA PRODUCTS IN DEVELOPMENT 124
Glaukos' Micro-Invasive Glaucoma Surgery Products 125
iStent Inject Trabecular Micro-Bypass Stent 125
iStent Supra Suprachoroidal Micro-Bypass Stent 125
iDose 125
Ivantis' Hydrus Microstent 126
InnFocus' Microshunt 126
Transcend Medical's CyPass Glaucoma Micro-Stent 127
Aquesys' XEN Gel Stent 128
EyeSonix' Low Power Ultrasound Device 128
CONTACT LENSES IN DEVELOPMENT 129
TABLE 17 CONTACT LENS PRODUCTS IN DEVELOPMENT-PHASE III 129
Brien Holden Vision's Extended Depth of Focus Contact Lenses 129
OTHER NEW PRODUCTS IN DEVELOPMENT 130
TREATMENTS FOR AGE-RELATED MACULAR DEGENERATION 130
SalutarisMD's Wet AMD Technology 130
Oraya Therapeutics' Oraya Therapy for Wet AMD 131
Second Sight's Argus II System for Dry AMD 131
Allergan's OD-01 for Dry Eye 132
Carl Zeiss' OCT Angiography 132
Alcon and ''Smart Lens'' Technology 133
Topcon's Diagnostic System 133
RECENT MARKET ACTIVITY 134
MERGERS AND ACQUISITION 134
TABLE 18 RECENT MERGERS AND ACQUISITIONS, NOV, 2013- JULY, 2015 135
MAJOR RECENT TRANSACTIONS 136
Allergan to Acquire Oculeve 136
Rayner Acquires Aptissen's Ophthalmic Cataract Surgery Business 136
XIO Group to Acquire Lumenis 137
Alcon Acquires WaveTec Vision 137
Synergetics USA Acquires Sterimedix 137
The Cooper Acquires Sauflon Pharmaceuticals 138
Ellex Medical Lasers Acquires iScience Interventional's Canaloplasty
Business 138
Carl Zeiss Meditec Acquires Aaren Scientific 138
Abbott Medical Optics Acquires OptiMedica 138
Valeant Pharmaceuticals International Acquires Bausch and Lomb 139
Bausch and Lomb Acquires Technolas Perfect Vision, 139
Alcon Acquires SensoMotoric Instruments Ophthalmic Division 139
Alcon Acquires Endure Medical Systems 139
Bausch and Lomb Acquires Laboratorio Pförtner Cornealent 140
ALLIANCE AND LICENSING DEALS 140
TABLE 19 RECENT ALLIANCE AND LICENSING DEALS, JAN, 2012-JAN, 2015 141
NOTABLE MARKETING AND DISTRIBUTION DEALS 142
Ophtec and i-Optics 142
Abbott Medical Optics and Carl Zeiss Meditec in the United States 142
Valeant Pharmaceuticals and Croma in the United States 142
HOYA and i-Optics 143
Lumenis and Visionix in China 143
Bausch and Lomb and PhysIOL for IOLs 143
Bausch and Lomb and Leica Microsystems 143
TrueVision 3D Surgical and i-Optics 144
Quantel Medical and Iridex for MicroPulse Technology 144
Bausch and Lomb and Topcon Medical in Japan 144
NOTABLE RESEARCH AND DEVELOPMENT COLLABORATIONS 145
Carl Zeiss Meditec and Oraya Therapeutics 145
Alcon and Google's ''Smart Lens'' Technology 145
Bausch and Lomb and Cirle 146
Hoya and InnFocus 146
Topcon and A*STAR 146
CHAPTER 7 FUTURE OUTLOOK 149
TABLE 20 GLOBAL OPHTHALMIC DEVICE MARKET BY PRODUCT, THROUGH 2019 ($
MILLIONS) 149
TABLE 21 SUMMARY: MARKET CHALLENGES AND OPPORTUNITIES 150
CHAPTER 8 COMPANY PROFILES 152
ABBOTT MEDICAL OPTICS 152
ALCON 153
BAUSCH and LOMB 154
CARL ZEISS MEDITEC AG 155
COOPERVISION 157
ELLEX MEDICAL LASERS 157
GLAUKOS 158
HOYA 159
JOHNSON and JOHNSON 160
LUMENIS 161
NIDEK 162
QUANTEL MEDICAL 163
STAAR SURGICAL 164
TOPCON 165
CHAPTER 9 ACRONYMS 168
CHAPTER 10 REFERENCES AND WEBLINKS 171
INTRODUCTION REFERENCES 171
RECENT DEVELOPMENTS IN OPHTHALMIC DEVICES REFERENCES 171
PRODUCT PIPELINE REFERENCES 172
INTRODUCTION WEBLINKS 172
RECENT DEVELOPMENTS IN OPHTHALMIC DEVICES WEBLINKS 173

LIST OF TABLES

SUMMARY TABLE GLOBAL OPHTHALMIC DEVICE MARKET BY REGION, THROUGH
2019 ($ MILLIONS) 7
TABLE 1 PREVALENCE OF DIABETIC RETINOPATHY BY REGION (%) 17
TABLE 2 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE, THROUGH
2014 ($ MILLIONS) 25
TABLE 3 GLOBAL CONTACT LENS MARKET BY REGION, THROUGH 2019 ($ MILLIONS) 27
TABLE 4 GLOBAL CATARACT SURGERY DEVICE MARKET BY REGION, THROUGH 2019
($ MILLIONS) 28
TABLE 5 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY REGION, THROUGH 2019 ($
MILLIONS) 31
TABLE 6 U.S. OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE, THROUGH
2019 ($ MILLIONS) 32
TABLE 7 GLOBAL OPHTHALMOLOGY DEVICE MARKET BY PRODUCT TYPE. THROUGH
2019* ($ MILLIONS) 34
TABLE 8 EUROPEAN OPHTHALMIC DEVICE MARKET BY COUNTRY, THROUGH 2019 ($
MILLIONS) 36
TABLE 9 ASIA-PACIFIC OPHTHALMIC DEVICE MARKET BY COUNTRY, THROUGH 2019
($ MILLIONS) 37
TABLE 10 GLOBAL OPTHALMOLOGY DEVICE MARKET BY LEADING MANUFACTURERS,
2010-2014 ($ MILLIONS/%) 40
TABLE 11 REFRACTIVE SURGERY PRODUCTS 82
TABLE 12 CONTACT LENS PRODUCT LAUNCHES, APRIL, 2013-JUNE, 2015 109
TABLE 13 CATARACT SURGERY PRODUCTS IN LATE-STAGE DEVELOPMENT 113
TABLE 14 REFRACTIVE SURGERY PRODUCTS IN LATE-STAGE DEVELOPMENT 117
TABLE 15 PRESBYOPIA IMPLANTS IN DEVELOPMENT 120
TABLE 16 GLAUCOMA PRODUCTS IN DEVELOPMENT 124
TABLE 17 CONTACT LENS PRODUCTS IN DEVELOPMENT-PHASE III 129
TABLE 18 RECENT MERGERS AND ACQUISITIONS, NOV, 2013- JULY, 2015 135
TABLE 19 RECENT ALLIANCE AND LICENSING DEALS, JAN, 2012-JAN, 2015 141
TABLE 20 GLOBAL OPHTHALMIC DEVICE MARKET BY PRODUCT, THROUGH 2019 ($
MILLIONS) 149
TABLE 21 SUMMARY: MARKET CHALLENGES AND OPPORTUNITIES 150
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