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Plastic Prefillable Syringes

  • June 2015
  • -
  • Greystone Research Associates

Evolution - or Revolution – in Injectable Devices

The trend toward patient self-administration of injectables continues to have a broad influence on the drug delivery sector. While prefillable syringe manufacturers continue to improve and refine their products, from a materials technology standpoint the most dynamic developments are occurring in the refinement of PFS constructed of plastic rather than glass.

To date, plastic PFS have made significant inroads in EMS injectables, a segment dominated by Hospira’s Ansyr plastic PFS product line. Now, as materials technology continues to advance, market sector participants are targeting mainstream therapeutic drugs.

Market-driven Product Strategies

A longer life span is expected to translate to a growing number of patients diagnosed with chronic conditions. To counteract the financial and medical
infrastructure implications of this trend, pressure from the public sector and managed care organizations will place a premium on therapeutic
self-administration, an expectation that is creating an increased interest in routes of administration that are patient-friendly and cost-effective. Pharma company
decision makers have come to the realization that for many products, success no longer only depends on the medication itself but also on achieving a consumer-compatible form of packaging and application.

What You Will Learn

- What injectable drugs are currently delivered in plastic prefillable syringes, what are the device specifics, and who markets them?
- Who are the important plastic prefillable syringe suppliers, their manufacturing infrastructure and locations, their capabilities?
- What are the major factors driving plastic prefillable syringe demand?
- How important are drug developer-device manufacturer relationships and what are the key alliances in the industry?
- What are the essential design factors, material selection issues, technologies and market development issues for plastic prefillable syringe drug products?
- How are plastic prefillable syringes aligned with various drug classes and therapeutic markets?
- What are the significant economic, technology, and regulatory factors affecting plastic prefillable syringes?

Table Of Contents

Plastic Prefillable Syringes

Executive Summary
The Market Opportunity
Market Dynamics
The Trend toward Self-Administration
Shifting Demographics
Innovation in Disposable Device Designs
The Economics of Plastic Prefilled Syringes

What's Driving Interest in Plastic PFS?
Limitations of Glass
Injectable Drug Volumes and Viscosities
Therapeutic Demand Drivers
Competitive Landscape
Risk Factors

Plastic Prefillable Syringe Application Segments
Emergency Drugs
Diluents
Infusion
Hyaluronic Acid
Specialty Injectables

Plastic Prefillable Syringe Design and Technology Factors
Materials of Construction
Crystal Clear Polymer (CCP)
Cyclic Olefin Polymer (COP)
Cyclic Olefin Copolymer (COC)
Syringe Processing Technology
Molding
Syringe Coatings

Plastic Prefillable Syringe Brands
Cyclic Olefin Copolymer (COC)
Cyclic Olefin Polymer (COP)
Crystal Clear Polymer (CCP)
Unbranded Plastic Prefillable Syringes

Approved Plastic Prefilled Syringe Products
Cyclic Olefin Syringes
Other Plastic Syringes
Prefilled Syringe Supply Chain
Plastics Suppliers
Injection Molders

Market Factors
Regulatory Issues
Industry Standards
ISO 10993-1
USP Class VI
Plastic Syringe/Injection Device Integration
Patient Compliance and Ease of Use
Healthcare Economics

Company Profiles

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