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  4. > 2017-2021 France Nucleic Acid Testing/NAT Market: Growth Opportunities and Business Expansion Strategies for Instrument and Reagent Suppliers

Highlights

  • Comprehensive 1,125-page market segmentation analysis of the French NAT market.
  • Major issues pertaining to the French NAT laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next five years.
  • An extensive review of DNA probe and biochip technologies, test formats, detection methodologies, trends in testing automation and amplification methods.
  • Five-year test volume and reagent sales forecasts for the following categories:
                 - Infectious Diseases
                 - Cancer
                 - Forensic Testing
                 - Genetic Diseases
                 - Paternity Testing/HLA Typing
  • Review of testing methodologies and instrumentation technologies.
  • Feature comparison of automated and semiautomated analyzers.
  • Sales and market shares of leading suppliers.
  • Over 60 specific opportunities for NAT instruments, test systems, IT and auxiliary products.
  • Profiles of major suppliers, and emerging market entrants, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
  • Alternative market penetration strategies.
  • Potential market entry barriers and risks.
  • Business planning issues and concerns.

    Contains 1,125 pages and 58 tables

    Table Of Contents

    2017-2021 France Nucleic Acid Testing/NAT Market: Growth Opportunities and Business Expansion Strategies for Instrument and Reagent Suppliers
    I. Introduction
    II. Major Product Development Opportunities
    A. Instrumentation
    B. Reagent Kits and Test Systems/panels
    C. Computers, Software and Automation
    D. Auxiliary Products
    III. Design Criteria for Decentralized Testing Products
    IV. Alternative Market Penetration Strategies
    A. Internal Development
    B. Collaborative Arrangements
    C. University Contracts
    D. Distribution Strategies For Decentralized Testing
    Markets
    V. Potential Market Entry Barriers and Risks
    A. Market Maturity
    B. Cost Containment
    C. Competition
    D. Technological Edge And Limitations
    E. Patent Protection
    F. Regulatory Constraints
    G. Decentralized Testing Market Challenges
    VI. Worldwide Market and Technology Review
    A. DNA Sequencing
    1. Introduction
    2. Sequencing Methods
    3. Autoradiography
    4. The Human Genome Project
    5. Sequencing Automation

    6. Image Scanners
    7. Fluorescent Detection
    8. Gene Profiling
    9. Gene Expression
    10. Polymorphism Screening
    11. Protein Interaction Networks
    B. DNA and RNA Probe Technologies
    1. Basic Principles
    2. Probe Preparation
    3. The DNA Probe Test
    4. Test Formats
    5. Labeling Techniques
    6. Amplification Methods
    C. Detection Technologies

    1. Radioactive Methods
    a. Overview
    b. Major Isotopes
    O P-32
    O S-35
    O H-3
    O I-125
    2. Non-Isotopic Methods
    a. Enzymatic Labels
    b. Chemical Labeling
    O Indirect Chemical Labeling
    O Direct Chemical Labeling
    c. Fluorescence
    d. Chemiluminescence
    e. Electrical Conductivity
    D. Molecular Diagnostic Instrumentation Review

    1. Abbott LCx
    2. Beckman Coulter/Biomek FK
    3. BD Viper System with XTR Technology
    4. BD Innova
    5. Becton Dickinson SDA

    6. bioMerieux NucliSENS easyMAG
    7. bioMerieux NucliSENS easyQ and MiniMAG
    8. Bio-Rad GeneScope
    9. Cepheid GeneXpert
    10. Curetis Unyvero
    11. GenMark Dx eSensor XT-8
    12. Hologic/Gen-Probe Panther
    13. Hologic/Gen-Probe Tigris/DTS
    14. HTG Molecular Edge
    15. Life Technologies QuantStudio Dx
    16. Qiagen QIAsymphony RGQ
    17. Roche Cobas Amplicor
    18. Roche Cobas TaqMan 48
    19. Roche Cobas TaqMan
    20. Roche Cobas TaqMan AmpliPrep
    21. Roche LighCycler 480
    22. Roche Cobas 4800
    23. Roche Cobas s 201
    24. Siemens Versant
    25. Tecan LS Series
    E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
    - Liquid Transportation and Mixing
    - Separation
    - Reaction
    - Detection
    F. Pharmacogenomics
    G. Major Applications
    1. Microbiology/Infectious Diseases
    a. Overview
    b. Major Infectious Diseases
    ° AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT,
    Western Blot, HTLV-I/II
    ° Adenovirus
    ° Aeromonas
    ° Anthrax/Bacillus Anthracis

    ° Arboviruses
    ° Babesiosis
    ° Bacillary Epithelioid Angiomatosis (BEA)
    and Other Bartonella (Rochalimaea)
    ° Blastocystis Hominis
    ° Brucella
    ° Campylobacter
    ° Candida
    ° Chagas Disease
    ° Chancroid
    ° Chlamydia
    ° Clostridium Difficile
    ° Coronaviruses
    ° Coxsackieviruses
    ° Creutzfeldt-Jakob's Disease
    ° Cryptosporidium Parvum
    ° Cyclospora Cayetanensis
    ° Cytomegalovirus
    ° Ebola Virus
    ° E. Coli
    ° EchoVirus
    ° Encephalitis
    ° Enteroviruses
    ° Epstein-Barr Virus
    ° Giardia Lamblia
    ° Gonorrhea
    ° Granuloma Inguinale
    ° Hantavirus
    ° Helicobacter Pylori
    ° Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT,
    Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag,
    HBe Ag, ALT/SGPT
    ° Herpes Simplex Virus
    ° Human Herpes Virus-6 (HHV-6)
    ° Influenza Viruses
    ° Legionella
    ° Lyme Disease
    ° Lymphogranuloma Venereum (LGV)
    ° Malaria
    ° Measles (Rubeola)
    ° Meningitis

    ° Microsporidium
    ° Mononucleosis
    ° Mumps
    ° Mycoplasma
    ° Papillomaviruses
    ° Parvovirus B19
    ° Pneumonia
    ° Polyomaviruses
    ° Pseudomonas Aeruginosa
    ° Rabies
    ° Respiratory Syncytial Virus (RSV)
    ° Rhinoviruses
    ° Rotavirus
    ° Rubella
    ° Salmonellosis
    ° Septicemia
    ° Shigellosis
    ° Staphylococcus Aureus
    ° Streptococci
    ° Syphilis
    ° Toxoplasmosis
    ° Trichomonas Vaginalis
    ° Tuberculosis
    ° Vibrio
    ° West Nile Virus
    ° Yersina
    2. Cancer Testing
    a. Overview
    b. Major Cancer Types
    * Prostate
    * Lung
    * Colon and Rectum
    * Breast
    * Skin
    * Uterine
    * Leukemia
    * Oral
    c. Oncogenes
    O Abl/abl-bcr
    O AIB1

    O BCL-2
    O BRCA1
    O CD44
    O C-fos
    O C-myb
    O C-myc
    O CYP17
    O Erb-B
    O HPC1
    O N-myc
    O P40
    O P51
    O P53
    O PIK3CA
    O PTI-1
    O Ras
    O Reg
    O Sis
    O Src
    3. Genetic Diseases
    a. Overview
    b. Nucleic Acid Amplification
    c. Chromosome Imaging
    d. Genomics Technologies
    e. Proteomics Technologies
    f. Current Pharmacogenomic Tests
    g. Future Pharmacogenomic Testing
    h. Major Diseases
    * Achondroplasia
    * Autosomal Dominant Polycystic Kidney
    Disease
    * Cancer
    * Cosmetogenomics
    * Cystic Fibrosis
    * Down's Syndrome
    * Duchenne and Becker Muscular Dystrophy
    * Factor V (Leiden)
    * Factor IX Deficiency
    * Fragile X Syndrome

    * Heart Disease
    * Hemochomatosis
    * Hemophilia
    * Huntington's Disease
    * Maternal-Fetal Incompatibility
    * Multiple Endocrine Neoplasia
    * Phenylketonuria (PKU)
    * Polycystic Kidney Disease (PKD)
    * Prenatal Screening
    * Retinitis Pigmentosa
    * Retinoblastoma
    * Sickle Cell Anemia
    * Spinal Muscular Atrophy
    * Vitamin B12 Metabolism
    i. Social Issues and Concerns
    4. Forensic Testing
    a. Overview
    b. Multilocus and Single Locus Probes
    * Multilocus Probes
    * Single Locus Probes
    * PCR and RFLP
    c. The FBI
    d. DNA Profile Data Banks
    * U.S.A.
    * U.K.
    e. Judicial Implementation
    f. Major Crime Categories
    g. Factors Contributing to the DNA Probe
    Market Expansion
    * Technology Availability
    * Use of Hair as Evidence
    h. Wildlife Forensics
    5. Paternity Testing/HLA Typing
    6. Other Applications
    a. Disease Susceptibility Testing
    b. Cardiovascular Diseases
    c. Diabetes

    d. Alzheimer's Disease
    e. Periodontal Disease
    f. Plasma Purification
    g. Organ Transplantation
    h. Water Contamination
    i. Other
    H. Competing/complementing
    1. Monoclonal Antibodies/Immunoassays
    2. RNA Probes
    3. Two-Dimensional Electrophoresis
    4. Flow Cytometry
    VII. France Molecular Diagnostics Market
    A. Executive Summary
    B. Business Environment
    C. Market Structure
    D. Market Size, Test Volume and Sales Forecasts,
    Major Supplier Sales and Market Shares
    VIII. Competitive Assessments

    - Abbott
    - Affymetrix
    - Agilent Technologies
    - Applied Gene Technologies
    - Arca Biopharma
    - Beckman Coulter/Danaher
    - Becton Dickinson
    - Biokit
    - bioMerieux
    - Bio-Rad
    - Biotest
    - Cepheid
    - CellMark Forensics/LabCorp
    - Decode Genetics
    - Diadexus
    - Eiken
    - Elitech Group
    - Enzo

    - Exact Sciences
    - Fujirebio
    - Grifols
    - Hologic/Gen-Probe
    - Illumina
    - Kreatech/Leica
    - Li-Cor Biosciences
    - Monogram Biosciences/LabCorp
    - Myriad Genetics
    - Ortho-Clinical Diagnostics
    - Perkin Elmer/Caliper
    - Proteome Sciences
    - Qiagen
    - Roche
    - Scienion
    - Sequenom
    - Shimadzu
    - Siemens
    - Sierra Molecular
    - Takara Bio
    - Tecan Group
    - Thermo Fisher
    XIII. Appendix: Major Universities and Research Centers
    Developing Molecular Diagnostic Technologies


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