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  4. > 2016-2020 Spain Nucleic Acid Testing/NAT Market: Growth Opportunities and Business Expansion Strategies for Instrument and Reagent Suppliers

Highlights

  • Comprehensive 1,117-page market segmentation analysis of the Spanish NAT market.
  • Major issues pertaining to the Spanish NAT laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next five years.
  • An extensive review of DNA probe and biochip technologies, test formats, detection methodologies, trends in testing automation and amplification methods.
  • Five-year test volume and reagent sales forecasts for the following categories:
                 - Infectious Diseases
                 - Cancer
                 - Forensic Testing
                 - Genetic Diseases
                 - Paternity Testing/HLA Typing
  • Review of testing methodologies and instrumentation technologies.
  • Feature comparison of automated and semiautomated analyzers.
  • Sales and market shares of leading suppliers.
  • Over 60 specific opportunities for NAT instruments, test systems, IT and auxiliary products.
  • Profiles of major suppliers, and emerging market entrants, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
  • Alternative market penetration strategies.
  • Potential market entry barriers and risks.
  • Business planning issues and concerns.

Contains 1,117 pages and 55 tables

Table Of Contents

2016-2020 Spain Nucleic Acid Testing/NAT Market: Growth Opportunities and Business Expansion Strategies for Instrument and Reagent Suppliers
I. Introduction
II. Major Product Development Opportunities
A. Instrumentation
B. Reagent Kits and Test Systems/panels
C. Computers, Software and Automation
D. Auxiliary Products
III. Design Criteria for Decentralized Testing Products
IV. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies For Decentralized Testing
Markets
V. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge And Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
VI. Worldwide Market and Technology Review
A. DNA Sequencing
1. Introduction
2. Sequencing Methods
3. Autoradiography
4. The Human Genome Project
5. Sequencing Automation

6. Image Scanners
7. Fluorescent Detection
8. Gene Profiling
9. Gene Expression
10. Polymorphism Screening
11. Protein Interaction Networks
B. DNA and RNA Probe Technologies
1. Basic Principles
2. Probe Preparation
3. The DNA Probe Test
4. Test Formats
5. Labeling Techniques
6. Amplification Methods
C. Detection Technologies

1. Radioactive Methods
a. Overview
b. Major Isotopes
O P-32
O S-35
O H-3
O I-125
2. Non-Isotopic Methods
a. Enzymatic Labels
b. Chemical Labeling
O Indirect Chemical Labeling
O Direct Chemical Labeling
c. Fluorescence
d. Chemiluminescence
e. Electrical Conductivity
D. Molecular Diagnostic Instrumentation Review

1. Abbott LCx
2. Beckman Coulter/Biomek FK
3. BD Viper System with XTR Technology
4. BD Innova
5. Becton Dickinson SDA

6. bioMerieux NucliSENS easyMAG
7. bioMerieux NucliSENS easyQ and MiniMAG
8. Bio-Rad GeneScope
9. Cepheid GeneXpert
10. Curetis Unyvero
11. GenMark Dx eSensor XT-8
12. Hologic/Gen-Probe Panther
13. Hololgic/Gen-Probe Tigris/DTS
14. HTG Molecular Edge
15. Life Technologies QuantStudio Dx
16. Qiagen QIAsymphony RGQ
17. Roche Cobas Amplicor
18. Roche Cobas TaqMan 48
19. Roche Cobas TaqMan
20. Roche Cobas TaqMan AmpliPrep
21. Roche LighCycler 480
22. Roche Cobas 4800
23. Roche Cobas s 201
24. Siemens Versant
25. Tecan LS Series
E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
- Liquid Transportation and Mixing
- Separation
- Reaction
- Detection
F. Pharmacogenomics
G. Major Applications
1. Microbiology/Infectious Diseases
a. Overview
b. Major Infectious Diseases
° AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT,
Western Blot, HTLV-I/II
° Adenovirus
° Aeromonas
° Anthrax/Bacillus Anthracis

° Arboviruses
° Babesiosis
° Bacillary Epithelioid Angiomatosis (BEA)
and Other Bartonella (Rochalimaea)
° Blastocystis Hominis
° Brucella
° Campylobacter
° Candida
° Chagas Disease
° Chancroid
° Chlamydia
° Clostridium Difficile
° Coronaviruses
° Coxsackieviruses
° Creutzfeldt-Jakob's Disease
° Cryptosporidium Parvum
° Cyclospora Cayetanensis
° Cytomegalovirus
° Ebola Virus
° E. Coli
° EchoVirus
° Encephalitis
° Enteroviruses
° Epstein-Barr Virus
° Giardia Lamblia
° Gonorrhea
° Granuloma Inguinale
° Hantavirus
° Helicobacter Pylori
° Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT,
Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag,
HBe Ag, ALT/SGPT
° Herpes Simplex Virus
° Human Herpes Virus-6 (HHV-6)
° Influenza Viruses
° Legionella
° Lyme Disease
° Lymphogranuloma Venereum (LGV)
° Malaria
° Measles (Rubeola)
° Meningitis

° Microsporidium
° Mononucleosis
° Mumps
° Mycoplasma
° Papillomaviruses
° Parvovirus B19
° Pneumonia
° Polyomaviruses
° Pseudomonas Aeruginosa
° Rabies
° Respiratory Syncytial Virus (RSV)
° Rhinoviruses
° Rotavirus
° Rubella
° Salmonellosis
° Septicemia
° Shigellosis
° Staphylococcus Aureus
° Streptococci
° Syphilis
° Toxoplasmosis
° Trichomonas Vaginalis
° Tuberculosis
° Vibrio
° West Nile Virus
° Yersina
2. Cancer Testing
a. Overview
b. Major Cancer Types
* Prostate
* Lung
* Colon and Rectum
* Breast
* Skin
* Uterine
* Leukemia
* Oral
c. Oncogenes
O Abl/abl-bcr
O AIB1

O BCL-2
O BRCA1
O CD44
O C-fos
O C-myb
O C-myc
O CYP17
O Erb-B
O HPC1
O N-myc
O P40
O P51
O P53
O PIK3CA
O PTI-1
O Ras
O Reg
O Sis
O Src
3. Genetic Diseases
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
* Achondroplasia
* Autosomal Dominant Polycystic Kidney
Disease
* Cancer
* Cosmetogenomics
* Cystic Fibrosis
* Down's Syndrome
* Duchenne and Becker Muscular Dystrophy
* Factor V (Leiden)
* Factor IX Deficiency
* Fragile X Syndrome

* Heart Disease
* Hemochomatosis
* Hemophilia
* Huntington's Disease
* Maternal-Fetal Incompatibility
* Multiple Endocrine Neoplasia
* Phenylketonuria (PKU)
* Polycystic Kidney Disease (PKD)
* Prenatal Screening
* Retinitis Pigmentosa
* Retinoblastoma
* Sickle Cell Anemia
* Spinal Muscular Atrophy
* Vitamin B12 Metabolism
i. Social Issues and Concerns
4. Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
* Multilocus Probes
* Single Locus Probes
* PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
* U.S.A.
* U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe
Market Expansion
* Technology Availability
* Use of Hair as Evidence
h. Wildlife Forensics
5. Paternity Testing/HLA Typing
6. Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes

d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
H. Competing/complementing
1. Monoclonal Antibodies/Immunoassays
2. RNA Probes
3. Two-Dimensional Electrophoresis
4. Flow Cytometry
VII. Spain Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
VIII. Competitive Assessments

- Abbott
- Affymetrix
- Agilent Technologies
- Applied Gene Technologies
- Arca Biopharma
- Beckman Coulter/Danaher
- Becton Dickinson
- Biokit
- bioMerieux
- Bio-Rad
- Biotest
- Cepheid
- CellMark ForenVics/LabCorp
- Decode Genetics
- Diadexus
- Eiken
- Elitech Group
- Enzo

- Exact Sciences
- Fujirebio
- Grifols
- Hologic/Gen-Probe
- Illumina
- Kreatech/Leica
- Li-Cor Biosciences
- Monogram Biosciences/LabCorp
- Myriad Genetics
- Ortho-Clinical Diagnostics
- Perkin Elmer/Caliper
- Proteome Sciences
- Qiagen
- Roche
- Scienion
- Sequenom
- Shimadzu
- Siemens
- Sierra Molecular
- Takara Bio
- Tecan Group
- Thermo Fisher
XIII. Appendix: Major Universities and Research Centers
Developing Molecular Diagnostic Technologies



List of Tables
Major Companies Developing or Marketing AIDS Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Bartonella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Campylobacter
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Candida
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Chlamydia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Clostridium
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Coronavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Cryptosporidium
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Echovirus Molecular
Diagnostic and Other Direct Identification Tests

Major Companies Developing or Marketing Enterovirus Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Giardia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Gonorrhea
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Hantavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Helicobacter
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Hepatitis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Herpes
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Influenza
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Legionella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Lyme
Disease Molecular Diagnostic and Other Direct
Identification Tests

Major Companies Developing or Marketing Measles
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Meningitis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mononucleosis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mumps
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mycoplasma
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Pneumonia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing RSV
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Rotavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Rubella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Salmonella
Molecular Diagnostic and Other Direct
Identification Tests

Major Companies Developing or Marketing Septicemia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Shigella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Streptococci
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Syphilis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Toxoplasmosis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Trichomonas
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Tuberculosis
Molecular Diagnostic and Other Direct
Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer
Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular
Diagnostic Tests For Genetic Diseases

Spain
Molecular Diagnostics Test Volume And Sales
By Major Application
Spain
Laboratories Performing DNA Sequencing
By Market Segment
Spain
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment
Spain
Molecular Diagnostics Test Volume
By Major Application
Spain
Major Infectious Disease Test Volume by Assay
Spain
Major Infectious Disease Test Volume by Method
Spain
Molecular Diagnostics Market
By Major Application
Spain
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers
Spain
Major Infectious Disease Diagnostics Market by Assay
Spain
AIDS Testing Market
Estimated Sales by Major Supplier
Spain
Chlamydia Testing Market
Estimated Sales by Major Supplier

Spain
CMV Testing Market
Estimated Sales by Major Supplier
Spain
Gonorrhea Testing Market
Estimated Sales by Major Supplier
Spain
Hepatitis Testing Market
Estimated Sales by Major Supplier
Spain
Hepatitis C Testing Market
Estimated Sales by Major Supplier
Spain
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier
Spain
Herpes Testing Market
Estimated Sales by Major Supplier
Spain
Influenza Testing Market
Estimated Sales by Major Supplier
Spain
Meningitis Testing Market
Estimated Sales by Major Supplier
Spain
Mycoplasma Testing Market
Estimated Sales by Major Supplier

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