Orthobiologics - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016

Orthobiologics - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016

Summary

GlobalData’s new report, “Orthobiologics - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016” provides key data, information and analysis on the global orthobiologics market. The report provides market landscape, competitive landscape and market trends information the orthobiologics market. The report provides comprehensive information on the key trends affecting the market, and key analytical content on the market dynamics. The report also reviews the competitive landscape and technology offerings.

This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData’s team of industry experts.

Scope

- Key geographies covered include the US, Canada, the UK, Germany, France, Italy, Spain, Japan, China, India, Australia, and Brazil.
- Key segments covered include Bone Allografts, Bone Graft Substitutes (Synthetic Bone Graft Substitutes, and bone morphogenic proteins), Bone Growth Stimulators, Demineralized Bone Matrix (DBM), and Viscosupplementation.
- Annualized market revenues data from 2002 to 2009, forecast forward for 7 years to 2016. Company shares data for 2009.
- Qualitative analysis of key market trends, market drivers, and restraints by each category within orthobiologics market.
- The report also covers information on the leading market players, the competitive landscape, and the leading pipeline products and technologies.
- Key players covered include Medtronic, Genzyme Corporation, DePuy, Synthes, Smith & Nephew, and Stryker Corporation.

Reasons to buy

- Develop business strategies by understanding the trends and developments that are driving the orthobiologics market globally.
- Design and develop your product development, marketing and sales strategies.
- Develop market-entry and market expansion strategies.
- Identify key players best positioned to take advantage of the emerging market opportunities.
- Exploit in-licensing and out-licensing opportunities by identifying products, most likely to ensure a robust return.
- What’s the next big thing in the orthobiologics market landscape? – Identify, understand and capitalize.
- Make more informed business decisions from the insightful and in-depth analysis of the global orthobiologics market and the factors shaping it.

Global Orthopedic Industry

1 Table of contents
1 Table of contents 3
1.1 List of Tables 6
1.2 List of Figures 8
2 Introduction: Orthobiologics 9
2.1 GlobalData Report Guidance 9
3 Orthobiologics: Overview 10
3.1 Applications of Orthobiologics 11
4 Orthobiologics: Global Market Characterization 12
4.1 Orthobiologics Market, Global, Revenue ($m), Historic, 2002 – 2009 12
4.2 Orthobiologics Market, Global, Revenue ($m), Forecast, 2009 – 2016 14
4.3 Orthobiologics, Market Dynamics 15
4.3.1 Orthobiologics, Market Drivers 15
4.3.2 Orthobiologics, Market Restraints 17
5 Global Orthobiologics Market: Segment Analysis 18
5.1 Bone Graft Substitutes Market, Global, Revenue ($m), Historic, 2002 – 2009 18
5.2 Bone Graft Substitutes Market, Global, Revenue ($m), Forecast, 2009 – 2016 19
5.2.1 Bone Graft Substitutes, Market Drivers 20
5.2.2 Bone Graft Substitutes, Market Restraint: Safety Concerns over Bone Morphogenetic Protein in Spinal Fusion Surgeries and High Cost is Slowing the Adoption 20
5.3 Viscosupplementation Market, Global, Revenue ($m), Historic, 2002 – 2009 21
5.4 Viscosupplementation Market, Global, Revenue ($m), Forecast, 2009 – 2016 22
5.4.1 Viscosupplementation, Market Drivers 23
5.4.2 Viscosupplementation, Market Restraint: Pricing Challenges to Continue to Plague the Viscosupplementation Market 23
5.5 Demineralized Bone Matrix Market, Global, Revenue ($m), Historic, 2002 – 2009 24
5.6 Demineralized Bone Matrix Market, Global, Revenue ($m), Forecast, 2009 – 2016 25
5.6.1 Demineralized Bone Matrix, Market Drivers 26
5.6.2 Demineralized Bone Matrix, Market Restraint: Several Potential Disadvantages such as Potential to Transmit HIV may Act as Restraint for Market Growth 26
5.7 Bone Growth Stimulators Market, Global, Revenue ($m), Historic, 2002 – 2009 27
5.8 Bone Growth Stimulators Market, Global, Revenue ($m), Forecast, 2009 – 2016 28
5.8.1 Bone Growth Stimulators, Market Driver: Increasing Number of Fractures due to Aging is Expected to Drive the Market Growth for Bone Growth Stimulators 28
5.8.2 Bone Growth Stimulators, Market Restraint: Lack of Exact Knowledge about the Mechanism of Action for These Devices and Lack of Studies in Specific Patient Groups will Restrict their Adoption 28
5.9 Bone Allografts Market, Global, Revenue ($m), Historic, 2002–2009 29
5.10 Bone Allografts Market, Global, Revenue ($m), Forecast, 2009–2016 30
5.10.1 Bone Allografts, Market Driver: The Advantages Offered by Allografts over Autografts - the Elimination of Second Surgery to Drive the Market 31
5.10.2 Bone Allografts, Market Restraint: Complications Associated with Bone Allografts is Restraining their Adoption 31
6 Orthobiologics Market, Revenue ($m), by Country, 2002–2016 32
6.1 Orthobiologics Market, The US, Revenue ($m), Historic, 2002–2009 32
6.2 Orthobiologics Market, The US, Revenue ($m), Forecast, 2009–2016 33
6.3 Orthobiologics Market, Canada, Revenue ($m), Historic, 2002–2009 34
6.4 Orthobiologics Market, Canada, Revenue ($m), Forecast, 2009–2016 35
6.5 Orthobiologics Market, Germany, Revenue ($m), Historic, 2002–2009 36
6.6 Orthobiologics Market, Germany, Revenue ($m), Forecast, 2009–2016 37
6.7 Orthobiologics Market, The UK, Revenue ($m), Historic, 2002–2009 38
6.8 Orthobiologics Market, The UK, Revenue ($m), Forecast, 2009–2016 39
6.9 Orthobiologics Market, France, Revenue ($m), Historic, 2002–2009 40
6.10 Orthobiologics Market, France, Revenue ($m), Forecast, 2009–2016 41
6.11 Orthobiologics Market, Spain, Revenue ($m), Historic, 2002–2009 42
6.12 Orthobiologics Market, Spain, Revenue ($m), Forecast, 2009–2016 43
6.13 Orthobiologics Market, Italy, Revenue ($m), Historic, 2002–2009 44
6.14 Orthobiologics Market, Italy, Revenue ($m), Forecast, 2009–2016 45
6.15 Orthobiologics Market, Japan, Revenue ($m), Historic, 2002–2009 46
6.16 Orthobiologics Market, Japan, Revenue ($m), Forecast, 2009–2016 47
6.17 Orthobiologics Market, China, Revenue ($m), Historic, 2002-2009 48
6.18 Orthobiologics Market, China, Revenue ($m), Forecast, 2009–2016 49
6.19 Orthobiologics Market, India, Revenue ($m), Historic, 2002–2009 50
6.20 Orthobiologics Market, India, Revenue ($m), Forecast, 2009–2016 51
6.21 Orthobiologics Market, Australia, Revenue ($m), Historic, 2002–2009 52
6.22 Orthobiologics Market, Australia, Revenue ($m), Forecast, 2009–2016 53
6.23 Orthobiologics Market, Brazil, Revenue ($m), Historic, 2002–2009 54
6.24 Orthobiologics Market, Brazil, Revenue ($m), Forecast, 2009–2016 55
7 Global Orthobiologics Market: Strategic Competitive Assesment 56
7.1 Medtronic Inc. 57
7.1.1 Overview 57
7.2 Genzyme Corporation 58
7.2.1 Overview 58
7.3 Depuy, Inc.(Johnson & Johnson) 59
7.3.1 Overview 59
7.4 Synthes, Inc. 60
7.4.1 Overview 60
7.5 Smith & Nephew Plc 61
7.5.1 Overview 61
7.6 Stryker 62
7.6.1 Overview 62
7.7 Orthofix International N.V 63
7.7.1 Overview 63
8 Orthobiologics, Key Marketed Products 64
8.1 Bone Graft Substitutes 64
8.1.1 InFUSE (Medtronic, Inc.) 64
8.1.2 OP 1 Putty (Stryker) 64
8.1.3 chronOS (Synthes) 64
8.1.4 Healos Bone Graft Replacement 65
8.2 Viscosupplementation 65
8.2.1 Synvisc-one 65
8.2.2 SUPARTZ 66
8.3 Demineralized Bone Matrix 66
8.3.1 Optium DBM 66
8.3.2 DBX 66
8.3.3 VIAGRAF 66
8.4 Bone Growth Stimulators 67
8.4.1 Exogen 67
8.4.2 Physio-Stim 67
8.5 Bone Allograft 68
8.5.1 Allograft TLIF 68
8.5.2 Allograft PL 68
8.5.3 Trinity Evolution 68
9 Global Orthobiologics Market: Strategic Pipeline Assessment 69
9.1 Orthobiologics Market: Pipeline Products Summary 69
9.2 Profiles of Promising Products Under Clinical Development: 71
9.2.1 Synthetic Bone Graft Substitutes 71
9.2.2 BMP 73
9.2.3 Bone Growth Stimulators 74
9.2.4 Bone Allografts 75
9.2.5 Viscosupplementation 76
9.2.6 Demineralized Bone Matrix 77
9.3 Orthobilogics, List of Pipeline Products 77
9.3.1 Bone Morphogenetic Proteins, List of Pipeline Products 77
9.3.2 Bone Allografts, List of Pipeline Products 78
9.3.3 Bone Graft Substitutes, List of Pipeline Products 78
9.3.4 Bone Growth Stimulators, List of Pipeline Products 79
9.3.5 Demineralized Bone Matrix, List of Pipeline Products 79
9.3.6 Synthetic Bone Graft Substitutes, List of Pipeline Products 80
9.3.7 Viscosupplementation, List of Pipeline Products 81
9.3.8 Orthobiologics, List of Other Pipeline Products 81
10 Global Orthobiologics Market: Strategic Deal Analysis 84
10.1 Key Deals 87
10.1.1 Medtronic to Acquire Osteotech 87
10.1.2 Landec Acquires Lifecore Biomedical 87
10.1.3 Baxter International Completes Acquisition Of ApaTech 87
10.1.4 TiGenix Completes Acquisition Of OrthoMimetics 88
10.1.5 NuVasive Invests In Progentix Orthobiology 88
10.1.6 Kinetic Concepts Acquires LifeCell 88
10.1.7 Pioneer Surgical Technology Acquires Angstrom Medica 89
10.1.8 Pioneer Surgical Technology Acquires Encelle 89
10.1.9 Orthofix Acquires Blackstone Medical 89
11 Appendix 90
11.1 Definitions 91
11.1.1 Orthobiologics 91
11.2 Acronyms 91
11.3 Research Methodology 92
11.3.1 Secondary Research 92
11.3.2 Primary Research 92
11.3.3 Models 93
11.3.4 Forecasts 93
11.3.5 Expert Panel 93
11.4 GlobalData Consulting 93
11.5 Contact Us 94
11.6 Disclaimer 94

1.1 List of Tables

Table 1: Orthobiologics Market, Global, Revenue ($m), 2002–2009 12
Table 2: Orthobiologics Market, Global, Revenue ($m), 2009–2016 14
Table 3: Bone Graft Substitutes Market, Global, Revenue ($m), 2002–2009 18
Table 4: Bone Graft Substitutes Market, Global, Revenue ($m), 2009–2016 19
Table 5: Viscosupplementation Market, Global, Revenue ($m), 2002–2009 21
Table 6: Viscosupplementation Market, Global, Revenue ($m), 2009–2016 22
Table 7: Demineralized Bone Matrix Market, Global, Revenue ($m), 2002–2009 24
Table 8: Demineralized Bone Matrix Market, Global, Revenue ($m), 2009–2016 25
Table 9: Bone Growth Stimulators Market, Global, Revenue ($m), 2002–2009 27
Table 10: Bone Growth Stimulators Market, Global, Revenue ($m), 2009–2016 28
Table 11: Bone Allografts Market, Global, Revenue ($m), 2002–2009 29
Table 12: Bone Allografts Market, Global, Revenue ($m), 2009–2016 30
Table 13: Orthobiologics Market, The US, Revenue ($m), 2002-2009 32
Table 14: Orthobiologics Market, The US, Revenue ($m), 2009–2016 33
Table 15: Orthobiologics Market, Canada, Revenue ($m), 2002-2009 34
Table 16: Orthobiologics Market, Canada, Revenue ($m), 2009–2016 35
Table 17: Orthobiologics Market, Germany, Revenue ($m), 2002–2009 36
Table 18: Orthobiologics Market, Germany, Revenue ($m), 2009–2016 37
Table 19: Orthobiologics Market, The UK, Revenue ($m), 2002–2009 38
Table 20: Orthobiologics Market, The UK, Revenue ($m), 2009–2016 39
Table 21: Orthobiologics Market, France, Revenue ($m), 2002–2009 40
Table 22: Orthobiologics Market, France, Revenue ($m), 2009–2016 41
Table 23: Orthobiologics Market, Spain, Revenue ($m), 2002–2009 42
Table 24: Orthobiologics Market, Spain, Revenue ($m), 2009–2016 43
Table 25: Orthobiologics Market, Italy, Revenue ($m), 2002–2009 44
Table 26: Orthobiologics Market, Italy, Revenue ($m), 2009–2016 45
Table 27: Orthobiologics Market, Japan, Revenue ($m), 2002–2009 46
Table 28: Orthobiologics Market, Japan, Revenue ($m), 2009–2016 47
Table 29: Orthobiologics Market, China, Revenue ($m), 2002–2009 48
Table 30: Orthobiologics Market, China, Revenue ($m), 2009–2016 49
Table 31: Orthobiologics Market, India, Revenue ($m), 2002–2009 50
Table 32: Orthobiologics Market, India, Revenue ($m), 2009–2016 51
Table 33: Orthobiologics Market, Australia, Revenue ($m), 2002–2009 52
Table 34: Orthobiologics Market, Australia, Revenue ($m), 2009–2016 53
Table 35: Orthobiologics Market, Brazil, Revenue ($m), 2002–2009 54
Table 36: Orthobiologics Market, Brazil, Revenue ($m), 2009–2016 55
Table 37: Orthobiologics Market, Global, Company Revenue ($m), 2009 56
Table 38: Medtronic, Inc. , Marketed Products, 2010 57
Table 39: Medtronic, Pipeline Products, 2010 58
Table 40: Genzyme Corporation, Marketed Products, 2010 58
Table 41: Depuy, Marketed Products, 2010 59
Table 42: Depuy, Pipeline Products, 2010 59
Table 43: Synthes, Inc, Marketed Products, 2010 60
Table 44: Smith & Nephew, Marketed Products, 2010 61
Table 45: Smith & Nephew , Pipeline Products, 2010 61
Table 46: Stryker, Marketed Products, 2010 62
Table 47: Stryker , Pipeline Products, 2010 62
Table 48: Orthofix International, Marketed Products, 2010 63
Table 49: Orthofix International , Pipeline Products, 2010 63
Table 50: Infuse Bone Graft and the LT-Cage Device, Features and Benefits 64
Table 51: OP 1 Putty, Features and Benefits 64
Table 52: chronOS, Features and Benefits 65
Table 53: Healos Bone Graft Replacement, Features and Benefits 65
Table 54: Synvisc-one, Features and Benefits 65
Table 55: SUPARTZ, Features and Benefits 66
Table 56: Optium DBM, Features and Benefits 66
Table 57: DBX; Features and Benefits 66
Table 58: VIAGRAF, Features and Benefits 67
Table 59: Exogen, Features and Benefits 67
Table 60: Physio-Stim, Features and Benefits 67
Table 61: Allograft TLIF, Features and Benefits 68
Table 62: Allograft PL, Features and Benefits 68
Table 63: Trinity Evolution, Features and Benefits 68
Table 64: Orthobiologics Market, Global, Pipeline Products by Development Stage, 2010 69
Table 65: Orthobiologics Market, Global, Pipeline Products by Segment, 2010 70
Table 66: To Evaluate The Safety And Effectiveness Of GEM OS1 Compared To Autologous Bone Graft As A Bone Regeneration Device In Foot And Ankle Fusions 71
Table 67: The Efficacy Of rhBMP-2 For Posterolateral Lumbar Fusion In Smokers. 73
Table 68: Bone Morphogenetic Proteins, Pipeline Products, 2010 77
Table 69: Bone Allografts, Pipeline Products, 2010 78
Table 70: Bone Graft Substitutes, Pipeline Products, 2010 78
Table 71: Bone Growth Stimulators, Pipeline Products, 2010 79
Table 72: Demineralized Bone Matrix, Pipeline Products, 2010 79
Table 73: Synthetic Bone Graft Substitutes, Pipeline Products, 2010 80
Table 74: Viscosupplementation, Pipeline Products, 2010 81
Table 75: Orthobiologics, Pipeline Products, Others, 2010 81
Table 76: Orthobiologics, Pipeline Products, Others, 2010 82
Table 77: Orthobiologics, Pipeline Products, Others, 2010 83
Table 78: Orthobiologics Market, Key Deals, 2006–2010* 85

1.2 List of Figures

Figure 1: Orthobiologics, Market Segments, 2010 10
Figure 2: Orthobiologics Market, Global, Revenue ($m), 2002–2009 12
Figure 3: Orthobiologics Market, Global, Revenue ($m), 2009–2016 14
Figure 4: Orthobiologics Market, Drivers and Restraints 15
Figure 5: Bone Graft Substitutes Market, Global, Revenue ($m), 2002–2009 18
Figure 6: Bone Graft Substitutes Market, Global, Revenue ($m), 2009–2016 19
Figure 7: Viscosupplementation Market, Global, Revenue ($m), 2002–2009 21
Figure 8: Viscosupplementation Market, Global, Revenue ($m), 2009–2016 22
Figure 9: Demineralized Bone Matrix Market, Global, Revenue ($m), 2002–2009 24
Figure 10: Demineralized Bone Matrix Market, Global, Revenue ($m), 2009–2016 25
Figure 11: Bone Growth Stimulators Market, Global, Revenue ($m), 2002–2009 27
Figure 12: Bone Growth Stimulators Market, Global, Revenue ($m), 2009–2016 28
Figure 13: Bone Allografts Market, Global, Revenue ($m), 2002–2009 29
Figure 14: Bone Allografts Market, Global, Revenue ($m), 2009–2016 30
Figure 15: Orthobiologics Market, The US, Revenue ($m), 2002–2009 32
Figure 16: Orthobiologics Market, The US, Revenue ($m), 2009–2016 33
Figure 17: Orthobiologics Market, Canada, Revenue ($m), 2002–2009 34
Figure 18: Orthobiologics Market, Canada, Revenue ($m), 2009–2016 35
Figure 19: Orthobiologics Market, Germany, Revenue ($m), 2002–2009 36
Figure 20: Orthobiologics Market, Germany, Revenue ($m), 2009–2016 37
Figure 21: Orthobiologics Market, The UK, Revenue ($m), 2002–2009 38
Figure 22: Orthobiologics Market, The UK, Revenue ($m), 2009–2016 39
Figure 23: Orthobiologics Market, France, Revenue ($m), 2002–2009 40
Figure 24: Orthobiologics Market, France, Revenue ($m), 2009–2016 41
Figure 25: Orthobiologics Market, Spain, Revenue ($m), 2002–2009 42
Figure 26: Orthobiologics Market, Spain, Revenue ($m), 2009–2016 43
Figure 27: Orthobiologics Market, Italy, Revenue ($m), 2002–2009 44
Figure 28: Orthobiologics Market, Italy, Revenue ($m), 2009–2016 45
Figure 29: Orthobiologics Market, Japan, Revenue ($m), 2002–2009 46
Figure 30: Orthobiologics Market, Japan, Revenue ($m), 2009–2016 47
Figure 31: Orthobiologics Market, China, Revenue ($m), 2002-2009 48
Figure 32: Orthobiologics Market, China, Revenue ($m), 2009–2016 49
Figure 33: Orthobiologics Market, India, Revenue ($m), 2002–2009 50
Figure 34: Orthobiologics Market, India, Revenue ($m), 2009–2016 51
Figure 35: Orthobiologics Market, Australia, Revenue ($m), 2002–2009 52
Figure 36: Orthobiologics Market, Australia, Revenue ($m), 2009–2016 53
Figure 37: Orthobiologics Market, Brazil, Revenue ($m), 2002–2009 54
Figure 38: Orthobiologics Market, Brazil, Revenue ($m), 2009–2016 55
Figure 39: Orthobiologics Market, Global, Company Share (%), 2009 56
Figure 40: Medtronic, Inc. , Pipeline Products, 2010 58
Figure 41: Depuy, Pipeline Products, 2010 59
Figure 42: Smith & Nephew , Pipeline Products, 2010 61
Figure 43: Stryker , Pipeline Products, 2010 62
Figure 44: Orthofix International , Pipeline Products, 2010 63
Figure 45: Orthobiologics Market, Global, Pipeline Products by Development Stage, 2010 69
Figure 46: Orthobiologics Market, Global, Pipeline Products by Segment, 2010 70
Figure 47: Orthobiologics Market, Deal Analysis, Value ($m) and Volume, 2006–2010* 84

Companies Mentioned
Medtronic Inc.
Genzyme Corporation
Depuy, Inc.(Johnson & Johnson)
Synthes, Inc.
Smith & Nephew Plc
Stryker
Orthofix International N.V