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  4. > Spine Biologics Market by Product Type, Surgery Type, End User, and Geography - Global Forecast to 2020

Spine Biologics Market, By Product (Bone Grafts, Bone Grafts Substitutes, Platelet-rich Plasma, Bone Marrow Aspirate Therapy), By Surgery Type (Anterior Cervical Discectomy and Fusion (ACDF), Posterior Lumbar Interbody Fusion (PLIF), Transforaminal Lumbar Interbody Fusion (TLIF), Anterior Lumbar Interbody Fusion (ALIF), Lateral Lumbar Interbody Fusion (LLIF)), by Geography – Global Forecasts to 2020

Spinal biologics are devices that are used extensively for bone fusion surgery, spinal cord injury, and degenerative disk disease. The treatment may include the use of allografts, autografts, mesenchymal stem cells, demineralized bone matrix, bone morphogenetic protein, and ceramics. These materials assist the body’s natural healing processes and are used to heal spine diseased or degenerated discs. The effects is perceived through increased cellular activity, growth, and differentiation. For example, in case of materials such as pedicle rods and screws used in spine fusion cases to provide spinal stability and fusion healing. However, since metals are inert in nature, they do not stimulate or activate cellular growth or alter cellular functions such as natural healing. Biologic materials are increasingly being preferred by surgeons performing spinal fusion surgeries as their use facilitates the fusion process due to their stimulant effect on spine fusion. The global spine biologics market constituted 33.5% of the global spinal implants and spinal devices market in 2014.

Spine biologics find application in spine surgery as lieu allografts as well as a support for bones in and around the spinal region. They can also be used cure the spinal injuries or trauma or degenerated discs. Currently, bone morphogenetic proteins (BMP’s) are biologic materials that are predominantly used in spinal surgery. Bone graft substitutes claim for around 85% share of the total spine biologics market.

The global spine biologics market size is expected to reach $2.4 billion by 2020, at a CAGR of 4.4% during the forecast period of 2015 to 2020. Growing aging population and rise in the application of minimally invasive surgeries are the major factors influencing the growth of this market.

The global spine biologics market report studies the major regions, namely, North America, Europe, Asia-Pacific, and Rest of the World (RoW).

In 2014, North America estimated accounted for the largest share of the global spine biologics market. As growth of healthcare industry is affected by the healthcare expenditure, increased investments in life sciences are expected to fuel the growth of the global spine biologics market in this region. The European spine biologics market is the second-largest. APAC is estimated to be the fastest growing market for spine biologics during the forecast period.

The report includes company profiles of major players, recent activities in the market, new product launches, mergers & acquisitions, collaborations and partnerships, and SWOT analysis. Some of the companies profiled in this report are Medtronic Inc. (U.S.), DePuy Synthes Companies (U.S.), Zimmer Holding Inc. (U.S.), Nuvasive Inc. (U.S.), Stryker Corporation (U.S.), Orthofix International N.V. (U.S.), K2M Inc. (U.S.), Exactech Inc. (U.S.), and Wright Medical Technology Inc. (U.S.), among others.


Reasons to Buy the Report:

From an insight perspective, this research report has focused on various levels of analysis, namely, industry analysis (industry trends and PEST analysis), market share analysis of top players, supply chain analysis, and company profiles. All of these together comprise and discuss the basic views on the competitive landscape, usage patterns, emerging- and high-growth segments, high-growth regions and countries and their respective regulatory policies, government initiatives, drivers, restraints, and opportunities for the global spine biologics market.

The report will enrich both established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in turn will help them garner a greater market share. Firms purchasing the report could use any one or a combination of the below mentioned five strategies to strengthen their market share.

The report provides insights on the following pointers:
- Product Analysis and Development: Detailed insights on upcoming technologies, research and development activities, and new product launches in the global spine biologics market are provided.
- Market Development: Comprehensive information about lucrative emerging markets is provided. The report also analyzes the markets for spine biologics across various regions, exploit new distribution channels, new clientele base, and different pricing policies.
- Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments decisions in the Global spine biologics market is provided. Detailed description regarding the related and unrelated diversification pertaining to this market is also provided.
- Competitive Assessment: An in-depth assessment of market shares and company share analysis of the key players forecasted till 2020 is provided.

Table Of Contents

Spine Biologics Market by Product Type, Surgery Type, End User, and Geography - Global Forecast to 2020
TABLE OF CONTENTS

1 INTRODUCTION 11
1.1 OBJECTIVES OF THE STUDY 11
1.2 MARKET SEGMENTATION and COVERAGE 12
1.3 STAKEHOLDERS 12
2 RESEARCH METHODOLOGY 13
2.1 INTEGRATED ECOSYSTEM OF SPINE BIOLOGICS MARKET 14
2.2 ARRIVING AT THE SPINE BIOLOGICS MARKET SIZE 15
2.2.1 TOP-DOWN APPROACH 16
2.2.2 BOTTOM-UP APPROACH 17
2.2.3 MACRO INDICATOR-BASED APPROACH 18
2.3 ASSUMPTIONS 19
3 EXECUTIVE SUMMARY 20
4 MARKET OVERVIEW 22
4.1 INTRODUCTION 22
4.2 MARKET DRIVERS AND INHIBITORS 23
5 SPINE BIOLOGICS MARKET, BY SURGERY TYPE 25
5.1 INTRODUCTION 26
5.2 ANTERIOR CERVICAL DISCECTOMY AND FUSION (ACDF) 27
5.3 POSTERIOR LUMBAR INTERBODY FUSION (PLIF) 29
5.4 TRANSFORAMINAL LUMBAR INTERBODY FUSION (TLIF) 29
5.5 ANTERIOR LUMBAR INTERBODY FUSION (ALIF) 32
5.6 LATERAL LUMBAR INTERBODY FUSION (LLIF) 34
5.7 OTHERS 36
6 SPINE BIOLOGICS MARKET BY PRODUCT TYPE 37
6.1 INTRODUCTION 38
6.2 BONE GRAFT 39
6.2.1 AUTOGRAFT 40
6.2.2 ALLOGRAFT 40
6.3 BONE GRAFT SUBSTITUTES 42
6.3.1 SYNTHETIC BONE GRAFTS 42
6.3.2 DEMINERALIZED BONE MATRIX (DBM) 45
6.3.3 BONE MORPHOGENETIC PROTEINS (BMP) 47
6.4 PLATELET RICH PLASMA (PRP) 49
6.5 BONE MARROW ASPIRATE (BMAC) THERAPY 50
7 SPINE BIOLOGICS MARKET, BY GEOGRAPHY 52
7.1 INTRODUCTION 53
7.2 NORTH AMERICA 54
7.2.1 SPINE BIOLOGICS MARKET, BY COUNTRY 55
7.2.2 SPINE BIOLOGICS MARKET, BY PRODUCT TYPE 56
7.2.3 BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE 57
7.2.4 SPINE BIOLOGICS MARKET, BY SURGERY TYPE 58
7.3 EUROPE 59
7.3.1 SPINE BIOLOGICS MARKET, BY COUNTRY 60
7.3.2 SPINE BIOLOGICS MARKET, BY PRODUCT TYPE 61
7.3.3 BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE 62
7.3.4 SPINE BIOLOGICS MARKET, BY SURGERY TYPE 63
7.4 ASIA PACIFIC 64
7.4.1 SPINE BIOLOGICS MARKET, BY COUNTRY 65
7.4.2 SPINE BIOLOGICS MARKET, BY PRODUCT TYPE 66
7.4.3 BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE 67
7.4.4 SPINE BIOLOGICS MARKET, BY SURGERY TYPE 68
8 COMPETITIVE LANDSCAPE 69
8.1 COMPANY SHARE ANALYSIS 69
8.2 PRODUCT LAUNCHES 70
8.3 MERGERS AND ACQUISITIONS 71
8.4 COLLABORATIONS, JOINT AGREEMENTS and EXPANSIONS, PARTNERSHIPS 72
8.5 APPROVALS, ALLIANCES, RELOCATION and LICENSING 73
9 COMPANY PROFILES 74
(Overview, Financials, Products and Services, Strategy, and Developments)*
9.1 ZIMMER HOLDING, INC. 74
9.2 DEPUY SYNTHES 77
9.3 MEDTRONIC, INC. (U.S.) 79
9.4 NUVASIVE, INC. 82
9.5 STRYKER CORPORATION 84
9.6 ORTHOFIX INTERNATIONAL N.V. 86
9.7 K2M, INC. 88
9.8 EXACTECH, INC. 90
9.9 WRIGHT MEDICAL TECHNOLOGY, INC. 92
9.10 NUTECH 95
9.11 ARTHREX, INC. 96
9.12 X-SPINE SYSTEMS, INC. (BACTERIN INTERNATIONAL HOLDINGS, INC.) 97
9.13 DR PRP USA LLC 98
*Details on overview, financials, product and services, strategy, and developments might not be captured in case of unlisted company
10 APPENDIX 99
10.1 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 99
10.2 CUSTOMIZATION OPTIONS 100
10.2.1 PRODUCT ANALYSIS 100
10.2.2 SPINE SURGEONS/ DOCTORS PERCEPTION ANALYSIS 100
10.2.3 REGULATORY FRAMEWORK 100
10.2.4 COMPETITIVE INTELLIGENCE 100
10.3 RELATED REPORTS 101


LIST OF TABLES

TABLE 1 SPINE BIOLOGICS MARKET: HEALTHCARE EXPENDITURE, BY GEOGRAPHY,
2014 (USD MILLION) 18
TABLE 2 SPINE BIOLOGICS MARKET, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 22
TABLE 3 SPINE BIOLOGICS MARKET, BY SURGERY TYPE, 2013-2020 (USD MILLION) 23
TABLE 4 SPINE BIOLOGICS MARKET, BY GEOGRAPHY, 2013-2020 (USD MILLION) 23
TABLE 5 SPINE BIOLOGICS MARKET: DRIVERS AND INHIBITORS 23
TABLE 6 SPINE BIOLOGICS MARKET, BY SURGERY TYPE, 2013-2020 (USD MILLION) 27
TABLE 7 SPINE BIOLOGICS MARKET IN ANTERIOR CERVICAL DISCECTOMY AND FUSION (ACDF) SURGERY, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 28
TABLE 8 SPINE BIOLOGICS MARKET IN ANTERIOR CERVICAL DISCECTOMY AND FUSION (ACDF) SURGERY, BY GEOGRAPHY, 2013-2020 (USD MILLION) 28
TABLE 9 SPINE BIOLOGICS MARKET IN TRANSFORAMINAL LUMBAR INTERBODY FUSION (TLIF) SURGERY, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 30
TABLE 10 SPINE BIOLOGICS MARKET IN TRANSFORAMINAL LUMBAR INTERBODY FUSION (TLIF) SURGERY, BY GEOGRAPHY, 2013-2020 (USD MILLION) 31
TABLE 11 SPINE BIOLOGICS MARKET IN ANTERIOR LUMBAR INTERBODY FUSION (ALIF) SURGERY, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 32
TABLE 12 SPINE BIOLOGICS MARKET IN ANTERIOR LUMBAR INTERBODY FUSION (ALIF) SURGERY, BY GEOGRAPHY, 2013-2020 (USD MILLION) 33
TABLE 13 SPINE BIOLOGICS MARKET IN LATERAL LUMBAR INTERBODY FUSION (LLIF) SURGERY, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 35
TABLE 14 SPINE BIOLOGICS MARKET IN LATERAL LUMBAR INTERBODY FUSION (LLIF) SURGERY, BY GEOGRAPHY, 2013-2020 (USD MILLION) 35
TABLE 15 SPINE BIOLOGICS MARKET VALUE BY PRODUCT TYPE, 2013-2020 (USD MILLION) 38
TABLE 16 BONE GRAFTS MARKET VALUE BY SURGERY TYPE, 2013-2020 (USD MILLION) 41
TABLE 17 BONE GRAFTS MARKET VALUE BY GEOGRAPHY, 2013-2020 (USD MILLION) 41
TABLE 18 BONE GRAFT SUBSTITUTES MARKET VALUE BY PRODUCT TYPE,
2013-2020 (USD MILLION) 42
TABLE 19 SYNTHETIC BONE GRAFTS MARKET VALUE BY SURGERY TYPE,
2013-2020 (USD MILLION) 43
TABLE 20 SYNTHETIC BONE GRAFTS MARKET VALUE BY GEOGRAPHY,
2013-2020 (USD MILLION) 44
TABLE 21 DEMINERALIZED BONE MATRIX (DBM) MARKET VALUE BY SURGERY TYPE,
2013-2020 (USD MILLION) 46
TABLE 22 DEMINERALIZED BONE MATRIX (DBM) MARKET VALUE BY GEOGRAPHY,
2013-2020 (USD MILLION) 47
TABLE 23 BONE MORPHOGENETIC PROTEIN (BMP) MARKET VALUE BY SURGERY TYPE,
2013-2020 (USD MILLION) 48
TABLE 24 BONE MORPHOGENETIC PROTEIN (BMP) MARKET VALUE BY GEOGRAPHY,
2013-2020 (USD MILLION) 49
TABLE 25 PLATELET RICH PLASMA (PRP) MARKET VALUE BY GEOGRAPHY,
2013-2020 (USD MILLION) 50
TABLE 26 BONE MARROW ASPIRATE CONCENTRATE (BMAC) THERAPY MARKET VALUE
BY GEOGRAPHY, 2013-2020 (USD MILLION) 51
TABLE 27 SPINE BIOLOGICS MARKET SIZE, BY GEOGRAPHY, 2013 - 2020 (USD MILLION) 53
TABLE 28 NORTH AMERICA: SPINE BIOLOGICS MARKET, BY COUNTRY,
2013-2020 (USD MILLION) 55
TABLE 29 NORTH AMERICA: SPINE BIOLOGICS MARKET, BY PRODUCT TYPE,
2013-2020 (USD MILLION) 56
TABLE 30 NORTH AMERICA: BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE,
2013-2020 (USD MILLION) 57
TABLE 31 NORTH AMERICA: SPINE BIOLOGICS MARKET, BY SURGERY TYPE,
2013-2020 (USD MILLION) 58
TABLE 32 EUROPE: SPINE BIOLOGICS MARKET, BY COUNTRY, 2013-2020 (USD MILLION) 60
TABLE 33 EUROPE: SPINE BIOLOGICS MARKET, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 61
TABLE 34 EUROPE: BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE,
2013-2020 (USD MILLION) 62
TABLE 35 EUROPE: SPINE BIOLOGICS MARKET, BY SURGERY TYPE, 2013-2020 (USD MILLION) 63
TABLE 36 ASIA PACIFIC: SPINE BIOLOGICS MARKET, BY COUNTRY, 2013-2020 (USD MILLION) 65
TABLE 37 ASIA PACIFIC: SPINE BIOLOGICS MARKET, BY PRODUCT TYPE, 2013-2020 (USD MILLION) 66
TABLE 38 ASIA PACIFIC: BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE,
2013-2020 (USD MILLION) 67
TABLE 39 ASIA PACIFIC: SPINE BIOLOGICS MARKET, BY SURGERY TYPE,
2013-2020 (USD MILLION) 68
TABLE 40 SPINE BIOLOGICS MARKET: COMPANY SHARE ANALYSIS, 2014 69
TABLE 41 PRODUCT LAUNCHES 70
TABLE 42 MERGERS AND ACQUISITIONS 71
TABLE 43 COLLABORATIONS, JOINT AGREEMENTS and EXPANSIONS 72
TABLE 44 APPROVALS, ALLIANCES, RELOCATION and LICENSING 73
TABLE 45 ZIMMER HOLDING, INC.: REVENUE, BY BUSINESS SEGMENT,
2009-2014 (USD MILLION) 75
TABLE 46 JOHNSON and JOHNSON LTD.: REVENUE, BY BUSINESS SEGMENT,
2011-2014 (USD MILLION) 77
TABLE 47 MEDTRONIC, INC. : REVENUE, BY BUSINESS SEGMENT, 2009-2013 (USD MILLION) 79
TABLE 48 NUVASIVE, INC.: REVENUE, BY PRODUCT TYPE, 2010-2014 (USD MILLION) 82
TABLE 49 STRYKER CORPORATION.: REVENUE, BY BUSINESS SEGMENT,
2010-2014 (USD MILLION) 84
TABLE 50 ORTHOFIX HOLDINGS, INC.: REVENUE, BY BUSINESS SEGMENT,
2012-2014 (USD MILLION) 86
TABLE 51 K2M INC.: REVENUE, 2011-2014 (USD MILLION) 88
TABLE 52 EXACTECH, INC.: REVENUE, BY BUSINESS SEGMENT, 2010-2014 (USD MILLION) 90
TABLE 53 EXACTECH, INC.: KEY FINANCIALS, BY GEOGRAPHY, 2010-2014 (USD MILLION) 91
TABLE 54 WRIGHT MEDICAL TECHNOLOGY, INC.: REVENUE, BY BUSINESS SEGMENT,
2011-2013 (USD MILLION) 92
TABLE 55 WRIGHT MEDICAL TECHNOLOGY, INC.: REVENUE, BY GEOGRAPHY,
2011-2013 (USD MILLION) 93


LIST OF FIGURES

FIGURE 1 SPINE BIOLOGICS MARKET: SEGMENTATION and COVERAGE 12
FIGURE 2 SPINE BIOLOGICS MARKET: INTEGRATED ECOSYSTEM 14
FIGURE 3 RESEARCH METHODOLOGY 15
FIGURE 4 TOP-DOWN APPROACH 16
FIGURE 5 BOTTOM-UP APPROACH 17
FIGURE 6 MACRO INDICATOR-BASED APPROACH (2014) 18
FIGURE 7 SPINE BIOLOGICS MARKET SNAPSHOT 21
FIGURE 8 SPINE BIOLOGICS MARKET, BY SURGERY TYPE, 2014 and 2020 (USD MILLION) 26
FIGURE 9 SPINE BIOLOGICS MARKET IN ANTERIOR CERVICAL DISCECTOMY AND FUSION (ACDF) SURGERY, BY PRODUCT TYPE, 2015 and 2020 (USD MILLION) 27
FIGURE 10 SPINE BIOLOGICS MARKET IN ANTERIOR CERVICAL DISCECTOMY AND FUSION (ACDF) SURGERY, BY GEOGRAPHY, 2015 and 2020 (USD MILLION) 28
FIGURE 11 SPINE BIOLOGICS MARKET IN TRANSFORAMINAL LUMBAR INTERBODY FUSION (TLIF) SURGERY, BY PRODUCT TYPE, 2015 and 2020 (USD MILLION) 30
FIGURE 12 SPINE BIOLOGICS MARKET IN TRANSFORAMINAL LUMBAR INTERBODY FUSION (TLIF) SURGERY, BY GEOGRAPHY, 2015 and 2020 (USD MILLION) 31
FIGURE 13 SPINE BIOLOGICS MARKET IN ANTERIOR LUMBAR INTERBODY FUSION (ALIF) SURGERY, BY PRODUCT TYPE, 2015 and 2020 (USD MILLION) 32
FIGURE 14 SPINE BIOLOGICS MARKET IN ANTERIOR LUMBAR INTERBODY FUSION (ALIF) SURGERY, BY GEOGRAPHY, 2015 and 2020 (USD MILLION) 33
FIGURE 15 SPINE BIOLOGICS MARKET IN LATERAL LUMBAR INTERBODY FUSION (LLIF) SURGERY, BY PRODUCT TYPE, 2015 and 2020 (USD MILLION) 34
FIGURE 16 SPINE BIOLOGICS MARKET IN LATERAL LUMBAR INTERBODY FUSION (LLIF) SURGERY, BY GEOGRAPHY, 2015 and 2020 (USD MILLION) 35
FIGURE 17 SPINE BIOLOGICS MARKET VALUE, BY PRODUCT TYPE, 2014 and 2020 (USD MILLION) 38
FIGURE 18 BONE GRAFTS MARKET VALUE, BY SURGERY TYPE, 2015 and 2020 (USD MILLION) 40
FIGURE 19 SPINE GRAFTS MARKET VALUE, BY GEOGRAPHY, 2015 and 2020 (USD MILLION) 41
FIGURE 20 BONE GRAFT SUBSTITUTES MARKET VALUE, BY PRODUCT TYPE,
2014 and 2020 (USD MILLION) 42
FIGURE 21 SYNTHETIC BONE GRAFTS MARKET VALUE, BY SURGERY TYPE,
2015 and 2020 (USD MILLION) 43
FIGURE 22 SYNTHETIC BONE GRAFTS MARKET VALUE, BY GEOGRAPHY,
2015 and 2020 (USD MILLION) 44
FIGURE 23 DEMINERALIZED BONE MATRIX (DBM) MARKET VALUE, BY SURGERY TYPE,
2015 and 2020 (USD MILLION) 45
FIGURE 24 DEMINERALIZED BONE MATRIX (DBM) MARKET VALUE, BY GEOGRAPHY,
2015 and 2020 (USD MILLION) 46
FIGURE 25 BONE MORPHOGENETIC PROTEIN (BMP) MARKET VALUE, BY SURGERY TYPE,
2015 and 2020 (USD MILLION) 48
FIGURE 26 BONE MORPHOGENETIC PROTEIN (BMP) MARKET VALUE, BY GEOGRAPHY,
2015 and 2020 (USD MILLION) 49
FIGURE 27 PLATELET RICH PLASMA (PRP) MARKET VALUE, BY GEOGRAPHY,
2015 and 2020 (USD MILLION) 50
FIGURE 28 BONE MARROW ASPIRATE CONCENTRATE (BMAC) THERAPY MARKET VALUE,
BY GEOGRAPHY, 2015 and 2020 (USD MILLION) 51
FIGURE 29 SPINE BIOLOGICS MARKET: GROWTH ANALYSIS, BY GEOGRAPHY,
2014 - 2020 (USD MILLION) 53
FIGURE 30 NORTH AMERICA: SPINE BIOLOGICS MARKET OVERVIEW, 2014 and 2020 (%) 54
FIGURE 31 NORTH AMERICA: SPINE BIOLOGICS MARKET, BY COUNTRY, 2015 and 2020 (USD MILLION) 55
FIGURE 32 NORTH AMERICA: SPINE BIOLOGICS MARKET, BY PRODUCT TYPE,
2015 and 2020 (USD MILLION) 56
FIGURE 33 NORTH AMERICA: BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE,
2015 and 2020 (USD MILLION) 57
FIGURE 34 NORTH AMERICA: SPINE BIOLOGICS MARKET, BY SURGERY TYPE,
2015 and 2020 (USD MILLION) 58
FIGURE 35 EUROPE: SPINE BIOLOGICS MARKET OVERVIEW, 2014 and 2020 (%) 59
FIGURE 36 EUROPE: SPINE BIOLOGICS MARKET, BY COUNTRY, 2015 and 2020 (USD MILLION) 60
FIGURE 37 EUROPE: SPINE BIOLOGICS MARKET, BY PRODUCT TYPE,
2015 and 2020 (USD MILLION) 61
FIGURE 38 EUROPE: BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE,
2015 and 2020 (USD MILLION) 62
FIGURE 39 EUROPE: SPINE BIOLOGICS MARKET, BY SURGERY TYPE,
2015 and 2020 (USD MILLION) 63
FIGURE 40 ASIA PACIFIC: SPINE BIOLOGICS MARKET OVERVIEW, 2014 and 2020 (%) 64
FIGURE 41 ASIA PACIFIC: SPINE BIOLOGICS MARKET, BY COUNTRY,
2015 and 2020 (USD MILLION) 65
FIGURE 42 ASIA PACIFIC: SPINE BIOLOGICS MARKET, BY PRODUCT TYPE,
2015 and 2020 (USD MILLION) 66
FIGURE 43 ASIA PACIFIC: BONE GRAFT SUBSTITUTES MARKET, BY PRODUCT TYPE,
2015 and 2020 (USD MILLION) 67
FIGURE 44 ASIA PACIFIC: SPINE BIOLOGICS MARKET, BY SURGERY TYPE,
2015 and 2020 (USD MILLION) 68
FIGURE 45 SPINE BIOLOGICS MARKET: COMPANY SHARE ANALYSIS, 2014 (%) 69
FIGURE 46 ZIMMER HOLDING, INC.: REVENUE MIX, 2014 (%) 74
FIGURE 47 JOHNSON and JOHNSON LTD.: BUSINESS REVENUE MIX, 2014 (%) 77
FIGURE 48 MEDTRONIC, INC.: REVENUE MIX, 2013 (%) 79
FIGURE 49 NUVASIVE INC.: REVENUE MIX, 2014 (%) 82
FIGURE 50 STRYKER CORPORATION: REVENUE MIX, 2014 (%) 84
FIGURE 51 ORTHOFIX INTERNATIONAL N.V.: BUSINESS REVENUE MIX, 2014 (%) 86
FIGURE 52 K2M, INC.: GEOGRAPHIC REVENUE MIX, 2014 (%) 88
FIGURE 53 EXACTECH, INC.: REVENUE MIX, 2014 (%) 90
FIGURE 54 WRIGHT MEDICAL TECHNOLOGY, INC.: REVENUE MIX, 2014 (%) 92

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