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3D Cell Culture Global Market – Forecast To 2021

  • January 2016
  • -
  • IQ4I Research & Consultancy Pvt. Ltd
  • -
  • 303 pages

3D cell culture is accepted as a new dimension of cell culture sector in biomedical research field. Cells grown on two-dimensional (2D) substrates do not represent true in-vivo cell environment and lack extracellular components, cell-cell and cell-matrix interactions necessary for differentiation, proliferation and cell-based functions. Hence, now-a-days three-dimensional (3D) cell culture methods are much preferred over 2D models as they provide a matrix support that encourages cells to organize into structures more indicative of the in--vivo environment and help to overcome 2D related shortcomings.

Increased use of 3D cell culture systems bring the hope of lowering lead molecule attrition rates but however, these models restricts huge data reproducibility, challenge assay readout systems and do not contain all cells relevant for tumour environment. In addition, the favourable artificial environment created by 3D model enables longer-term dosing experiments for analyzing drug’s cumulative effects.

According to IQ4I analysis, the 3D cell culture global market is poised to grow at a double digit CAGR to reach $3,702.2 million by 2021. The 3D cell culture market is classified based on types, applications, end-users and geography. The 3D cell culture by technology is segmented into scaffold based platform, scaffold free platform, bioreactors, microchips and hydrogels. Scaffold based platform is sub-segmented into natural scaffold, synthetic scaffold and hybrid composite. Natural scaffold is in-turn classified into protein based biomaterials (collagen, fibrin, silk, gelatin, elastin, keratin, actin and myosin, laminin and vitronectin) and polysaccharide based biomaterials (Agarose, alginate, hyaluronan, chitosan, amylase, dextran, cellulose and glycosaminoglycans). The synthetic scaffold is divided into polymer based biomaterials (Poly (lactic-co-glycolic acid), Polyethylene glycol, Polylactic acid, Polyglycolic acid, Polycapro lactone and polystyrene), peptide based biomaterials, ceramic based biomaterials (hydroxyapatite and bioactive glass) and metal based biomaterials (aluminium and titanium).

Scaffold free platform is sub-divided into low attachment surface, hanging drop method and microfluidics. The bioreactors segment consists of spinner flask, rotating wall vessel and perfusion bioreactors. The 3D cell culture consumables section contains cells and tissues, media and sera and reagent.

Further, the 3D culture market by application includes basic research, toxicity and drug safety screening, tissue engineering, stem cell research, drug discovery, gene therapy and cancer research. The 3D cell culture market is segmented into research laboratories and institutes, biotechnology and pharmaceutical industries, hospitals and diagnostic centers and others.

Finally, the 3D cell culture market is classified by geographical regions into North America, Europe, Asia-pacific and Rest of the World.

Table Of Contents

3D Cell Culture Global Market - Forecast To 2021

1 EXECUTIVE SUMMARY 25
2 INTRODUCTION 29
2.1 KEY TAKE AWAYS 29
2.2 REPORT DESCRIPTION 29
2.3 MARKETS COVERED 31
2.4 STAKEHOLDERS 33
2.5 RESEARCH METHODOLOGY 34
2.5.1 MARKET SIZE ESTIMATION 36
2.5.2 MARKET CRACKDOWN AND DATA TRIANGULATION 38
2.5.3 SECONDARY SOURCES 39
2.5.4 KEY DATA POINTS FROM SECONDARY SOURCES 40
2.5.5 PRIMARY SOURCES 41
2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 41
2.5.7 ASSUMPTIONS 41
3 MARKET ANALYSIS 43
3.1 INTRODUCTION 43
3.2 MARKET SEGMENTATION 44
3.3 FACTORS INFLUENCING MARKET 46
3.3.1 DRIVERS AND OPPORTUNITIES 47
3.3.1.1 Rise in research and development investments 47
3.3.1.2 Rising need for organ transplantation 47
3.3.1.3 Use of 3D cell culture models as a tool against animal testing 48
3.3.1.4 Use of microfluidic technology 48
3.3.1.5 Increasing focus on regenerative medicine 49
3.3.2 RESTRAINTS AND THREATS 50
3.3.2.1 Lack of experienced and skilled professionals 50
3.3.2.2 Budget restriction for small and medium sized laboratories. 50
3.3.2.3 Lack of consistency in 3D cell culture products 50
3.3.2.4 Stringent process controls for advanced handling capabilities 51
3.3.2.5 Ethical concern over use of animal sources 51
3.4 REGULATORY AFFAIRS 52
3.4.1 UNITED STATES 52
3.4.2 EUROPE 53
3.4.3 INDIA 54
3.4.4 JAPAN 55
3.5 TECHNOLOGICAL ADVANCEMENTS 56
3.5.1 INTRODUCTION 56
3.5.2 ORGAN-ON-CHIP 56
3.5.3 3D BIOPRINTING 57
3.5.4 3D VASCULARIZED ORGANS 57
3.5.5 MIMETIX 3D CELL CULTURE SCAFFOLDS 58
3.5.6 NANO CULTURE PLATES 58
3.6 UPCOMING TECHNOLOGIES 59
3.7 APPROVED BIOMATERIALS 62
3.8 PORTER'S FIVE FORCE ANALYSIS 64
3.8.1 THREAT OF NEW ENTRANTS 65
3.8.2 THREAT OF SUBSTITUTES 65
3.8.3 BARGAINING POWER OF SUPPLIERS 65
3.8.4 BARGAINING POWER OF BUYERS 66
3.8.5 RIVALRY AMONG EXISTING COMPETITORS 66
3.9 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 67
4 3D CELL CULTURE GLOBAL MARKET, BY TYPE 70
4.1 INTRODUCTION 70
4.2 BY TECHNOLOGY 73
4.2.1 INTRODUCTION 73
4.2.2 SCAFFOLD BASED PLATFORM 77
4.2.2.1 Natural scaffolds 80
4.2.2.1.1 Protein based biomaterials 82
4.2.2.1.1.1 Collagen 82
4.2.2.1.1.2 Fibrin 82
4.2.2.1.1.3 Silk 83
4.2.2.1.1.4 Gelatin 83
4.2.2.1.1.5 Elastin 84
4.2.2.1.1.6 Keratin 84
4.2.2.1.1.7 Laminin 84
4.2.2.1.1.8 Vitronectin 85
4.2.2.1.2 Polysaccharide based biomaterials 85
4.2.2.1.2.1 Agarose 85
4.2.2.1.2.2 Alginate 85
4.2.2.1.2.3 Hyaluronan 86
4.2.2.1.2.4 Chitosan 86
4.2.2.1.2.5 Dextran 87
4.2.2.1.2.6 Cellulose 87
4.2.2.1.2.7 Glycosaminoglycans 87
4.2.2.2 Synthetic scaffolds 88
4.2.2.2.1 Polymer based biomaterials 90
4.2.2.2.1.1 PLGA [Poly (lactic-co-glycolic acid)] 90
4.2.2.2.1.2 PEG (Polyethylene glycol) 91
4.2.2.2.1.3 PLA (Polylactic acid) 91
4.2.2.2.1.4 PS (Polystyrene) 91
4.2.2.2.1.5 PCL (Polycapro lactone) 92
4.2.2.2.2 Peptide based biomaterials 92
4.2.2.2.3 Ceramic based biomaterials 93
4.2.2.2.3.1 Hydroxyapatite (HA) 93
4.2.2.2.3.2 Bioactive glass 94
4.2.2.2.4 Metal based biomaterial 95
4.2.2.2.4.1Aluminium 95
4.2.2.2.4.2 Titanium 95
4.2.2.3 Hybrid composite 96
4.2.3 SCAFFOLD FREE PLATFORM 98
4.2.3.1 Low attachment surface 102
4.2.3.2 Hanging drop method 104
4.2.3.3 Microfluidics 106
4.2.4 BIOREACTORS 108
4.2.4.1 Spinner flasks 111
4.2.4.2 Rotating wall vessels (RWV) 113
4.2.4.3 Perfusion bioreactors 115
4.2.5 MICROCHIPS 117
4.2.6 HYDROGELS 119
4.3 BY CONSUMABLES 121
4.3.1 INTRODUCTION 121
4.3.2 CELLS AND TISSUES 124
4.3.3 MEDIA AND SERA 126
4.3.4 MICROPLATE AND REAGENTS 129
4.3.5 ASSAY KITS 132
5 3D CELL CULTURE GLOBAL MARKET, BY APPLICATIONS 134
5.1 INTRODUCTION 134
5.2 BASIC RESEARCH 137
5.3 TOXICITY AND DRUG SAFETY SCREENING 139
5.4 TISSUE ENGINEERING 141
5.5 STEM CELL RESEARCH 143
5.6 DRUG DISCOVERY 145
5.7 CANCER RESEARCH 147
5.8 GENE THERAPY 149
6 3D CELL CULTURE GLOBAL MARKET, BY END USERS 151
6.1 INTRODUCTION 151
6.2 ACADEMIC INSTITUTES 154
6.3 BIOTECHNOLOGY AND PHARMACEUTICAL INDUSTRIES 156
6.4 HOSPITALS AND DIAGNOSTIC CENTERS 158
6.5 OTHERS 160
7 REGIONAL ANALYSIS 162
7.1 INTRODUCTION 162
7.2 NORTH AMERICA 165
7.3 EUROPE 175
7.4 ASIA-PACIFIC 185
7.5 REST OF THE WORLD 195
8 COMPETITIVE LANDSCAPE 205
8.1 INTRODUCTION 205
8.2 NEW PRODUCT LAUNCHES 207
8.3 AGREEMENTS, PARTNERSHIP, COLLABORATION and JOINT VENTURES 215
8.4 EXPANSIONS, APPOVALS AND SERVICE LAUNCHES 221
8.5 MERGERS and ACQUISITIONS 222
9 MAJOR COMPANIES 224
9.1 3D BIOMATRIX 224
9.1.1 OVERVIEW 224
9.1.2 FINANCIALS 224
9.1.3 PRODUCTS PORTFOLIO 225
9.1.4 KEY DEVELOPMENTS 225
9.1.5 BUSINESS STRATEGY 227
9.1.6 SWOT ANALYSIS 228
9.2 3D BIOTEK LLC 229
9.2.1 OVERVIEW 229
9.2.2 FINANCIALS 229
9.2.3 PRODUCT PORTFOLIO 230
9.2.4 KEY DEVELOPMENTS 231
9.2.5 BUSINESS STRATEGY 231
9.2.6 SWOT ANALYSIS 232
9.3 BECTON, DICKINSON AND COMPANY 233
9.3.1 OVERVIEW 233
9.3.2 FINANCIALS 234
9.3.3 PRODUCT PORTFOLIO 237
9.3.4 KEY DEVELOPMENTS 238
9.3.5 BUSINESS STRATEGY 239
9.3.6 SWOT ANALYSIS 240
9.4 CORNING INCORPORATED 241
9.4.1 OVERVIEW 241
9.4.2 FINANCIALS 242
9.4.3 PRODUCT PORTFOLIO 245
9.4.4 KEY DEVELOPMENTS 247
9.4.5 BUSINESS STRATEGY 248
9.4.6 SWOT ANALYSIS 249
9.5 GLOBAL CELL SOLUTIONS, INC 250
9.5.1 OVERVIEW 250
9.5.2 FINANCIALS 250
9.5.3 PRODUCT PORTFOLIO 251
9.5.4 KEY DEVELOPMENTS 252
9.5.5 BUSINESS STRATEGY 252
9.5.6 SWOT ANALYSIS 253
9.6 INSPHERO AG 254
9.6.1 OVERVIEW 254
9.6.2 FINANCIALS 254
9.6.3 PRODUCT PORTFOLIO 255
9.6.4 KEY DEVELOPMENTS 256
9.6.5 BUSINESS STRATEGY 259
9.6.6 SWOT ANALYSIS 260
9.7 LONZA GROUP 261
9.7.1 OVERVIEW 261
9.7.2 FINANCIALS 262
9.7.3 PRODUCT PORTFOLIO 265
9.7.4 KEY DEVELOPMENTS 267
9.7.5 BUSINESS STRATEGY 269
9.7.6 SWOT ANALYSIS 270
9.8 NANO 3D BIOSCIENCES, INC 271
9.8.1 OVERVIEW 271
9.8.2 FINANCIALS 271
9.8.3 PRODUCT PORTFOLIO 272
9.8.4 KEY DEVELOPMENTS 273
9.8.5 BUSINESS STRATEGY 274
9.8.6 SWOT ANALYSIS 275
9.9 NANOFIBER SOLUTIONS 276
9.9.1 OVERVIEW 276
9.9.2 FINANCIALS 276
9.9.3 PRODUCT PORTFOLIO 277
9.9.4 KEY DEVELOPMENTS 278
9.9.5 BUSINESS STRATEGY 278
9.9.6 SWOT ANALYSIS 279
9.10 REPROCELL INCORPORATED 280
9.10.1 OVERVIEW 280
9.10.2 FINANCIALS 280
9.10.3 PRODUCT PORTFOLIO 281
9.10.4 KEY DEVELOPMENTS 282
9.10.5 BUSINESS STRATEGY 283
9.10.6 SWOT ANALYSIS 284
9.11 SIGMA ALDRICH CORPORATION 285
9.11.1 OVERVIEW 285
9.11.2 FINANCIALS 286
9.11.3 PRODUCT PORTFOLIO 289
9.11.4 KEY DEVELOPMENTS 290
9.11.5 BUSINESS STRATEGY 292
9.11.6 SWOT ANALYSIS 293
9.12 THERMO FISHER SCIENTIFIC, INC 294
9.12.1 OVERVIEW 294
9.12.2 FINANCIALS 295
9.12.3 PRODUCT PORTFOLIO 298
9.12.4 KEY DEVELOPMENTS 299
9.12.5 BUSINESS STRATEGY 302
9.12.6 SWOT ANALYSIS 303

LIST OF TABLES

TABLE 1 3D CELL CULTURE GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 28
TABLE 2 3D CELL CULTURE GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 71
TABLE 3 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 74
TABLE 4 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 75
TABLE 5 3D CELL CULTURE SCAFFOLD BASED PLATFORM GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 77
TABLE 6 3D CELL CULTURE SCAFFOLD BASED PLATFORM GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 78
TABLE 7 3D CELL CULTURE NATURAL SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 81
TABLE 8 3D CELL CULTURE SYNTHETIC SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 89
TABLE 9 3D CELL CULTURE HYBRID COMPOSITE SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 97
TABLE 10 3D CELL CULTURE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 99
TABLE 11 3D CELL CULTURE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 100
TABLE 12 LOW ATTACHMENT SURFACE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 103
TABLE 13 HANGING DROP METHOD SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 105
TABLE 14 MICROFLUIDICS SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 107
TABLE 15 3D CELL CULTURE BIORECTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 109
TABLE 16 3D CELL CULTURE BIOREACTORS GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 110
TABLE 17 3D CELL CULTURE SPINNER FLASK BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 112
TABLE 18 3D CELL CULTURE ROTATING WALL VESSEL BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 114
TABLE 19 3D CELL CULTURE PERFUSION BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 116
TABLE 20 3D CELL CULTURE MICROCHIPS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 118
TABLE 21 3D CELL CULTURE HYDROGELS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 120
TABLE 22 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 121
TABLE 23 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 122
TABLE 24 3D CELL CULTURE CELLS AND TISSUE CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 125
TABLE 25 3D CELL CULTURE MEDIA AND SERA CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 128
TABLE 26 3D CELL CULTURE MICROPLATE AND REAGENT CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 131
TABLE 27 3D CELL CULTURE ASSAY KITS CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 133
TABLE 28 3D CELL CULTURE GLOBAL MARKET REVENUE, BY APPLICATIONS, (2013-2021) ($MN) 135
TABLE 29 3D CELL CULTURE BASIC RESEARCH APPLICATION GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 138
TABLE 30 3D CELL CULTURE TOXICITY AND DRUG SAFETY SCREENING APPLICATION GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 140
TABLE 31 3D CELL CULTURE TISSUE ENGINEERING APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 142
TABLE 32 3D CELL CULTURE STEM CELL RESEARCH APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 144
TABLE 33 3D CELL CULTURE DRUG DISCOVERY APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 146
TABLE 34 3D CELL CULTURE CANCER RESEARCH APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 148
TABLE 35 3D CELL CULTURE GENE THERAPY APPLICATIONS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 150
TABLE 36 3D CELL CULTURE GLOBAL MARKET REVENUE, BY END-USERS, (2013-2021) ($MN) 152
TABLE 37 3D CELL CULTURE ACADEMIC INSTITUTES END-USERS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 155
TABLE 38 3D CELL CULTURE BIOTECHNOLOGY AND PHARMACEUTICALS INDUSTRIES END-USERS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 157
TABLE 39 3D CELL CULTURE HOSPITALS AND DIAGNOSTIC CENTRES END-USER GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 159
TABLE 40 3D CELL CULTURE OTHER END-USERS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 161
TABLE 41 3D CELL CULTURE GLOBAL MARKET REVENUE,BY REGION, (2013-2021) ($MN) 164
TABLE 42 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 167
TABLE 43 NORTH AMERICAN 3D CELL CULTURE TECHNOLOGY MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 168
TABLE 44 NORTH AMERICAN 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 169
TABLE 45 NORTH AMERICAN 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 170
TABLE 46 NORTH AMERICAN 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 171
TABLE 47 NORTH AMERICAN 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 172
TABLE 48 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY APPLICATIONS, (2013-2021) ($MN) 173
TABLE 49 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY END-USER, (2013-2021) ($MN) 174
TABLE 50 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 177
TABLE 51 EUROPEAN 3D CELL CULTURE TECHNOLOGY MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 178
TABLE 52 EUROPEAN 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 179
TABLE 53 EUROPEAN 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 180
TABLE 54 EUROPEAN 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 181
TABLE 55 EUROPEAN 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 182
TABLE 56 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY APPLICATION, (2013-2021) ($MN) 183
TABLE 57 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY END-USER, (2013-2021) ($MN) 184
TABLE 58 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 187
TABLE 59 ASIA-PACIFIC 3D CELL CULTURE TECHNOLOGY MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 188
TABLE 60 ASIA-PACIFIC 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 189
TABLE 61 ASIA-PACIFIC 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 190
TABLE 62 ASIA-PACIFIC 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 191
TABLE 63 ASIA-PACIFIC 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 192
TABLE 64 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY APPLICATION, (2013-2021) ($MN) 193
TABLE 65 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY END USERS, (2013-2021) ($MN) 194
TABLE 66 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 197
TABLE 67 REST OF THE WORLD 3D CELL CULTURE TECHNOLOGY MARKET REVENUE BY TYPE, (2013-2021) ($MN) 198
TABLE 68 REST OF THE WORLD 3D CELL CULTURE BIOREACTORS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 199
TABLE 69 REST OF THE WORLD 3D CELL CULTURE SCAFFOLD BASED PLATFORMS MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 200
TABLE 70 REST OF THE WORLD 3D CELL CULTURE SCAFFOLD FREE MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 201
TABLE 71 REST OF THE WORLD 3D CELL CULTURE CONSUMABLES MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 202
TABLE 72 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY APPLICATION, (2013-2021) ($MN) 203

TABLE 73 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY END-USER, (2013-2021) ($MN) 204
TABLE 74 NEW PRODUCT LAUNCHES (2013-2015) 207
TABLE 75 AGREEMENTS, PARTNERSHIP, COLLABORATION and JOINT VENTURES (2013-2015) 215
TABLE 76 EXPANSIONS, APPROVALS AND SERVICE LAUNCH (2013-2015) 221
TABLE 77 MERGERS and ACQUISITIONS (2013-2015) 222
TABLE 78 BECTON, DICKINSON AND COMPANY: TOTAL REVENUE AND RandD EXPENSES (2012-2014) ($MN) 234
TABLE 79 BECTON, DICKINSON AND COMPANY: TOTAL REVENUE, BY SEGMENTS (2012-2014) ($ MN) 235
TABLE 80 BECTON, DICKINSON AND COMPANY: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($ MN) 236
TABLE 81 CORNING INCORPORATED: TOTAL REVENUE AND RandD EXPENSES (2012-2014) ($MN) 242
TABLE 82 CORNING INCORPORATED: TOTAL REVENUE, BY SEGMENTS (2012-2014) ($MN) 243
TABLE 83 CORNING INCORPORATED: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($MN) 244
TABLE 84 LONZA GROUP: TOTAL REVENUE AND RandD EXPENSES (2012-2014) ($MN) 262
TABLE 85 LONZA GROUP: TOTAL REVENUE, BY SEGMENTS (2012-2014) ($MN) 263
TABLE 86 LONZA GROUP: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($MN) 264
TABLE 87 SIGMA ALDRICH'S: TOTAL REVENUE AND RandD EXPENSES, (2012-2014) ($MN) 286
TABLE 88 SIGMA ALDRICH'S: TOTAL REVENUE, BY SEGMENTS, (2012-2014) ($MN) 287
TABLE 89 SIGMA ALDRICH'S: TOTAL REVENUE, BY GEOGRAPHY, (2012-2014) ($MN) 288
TABLE 90 THERMO FISHER SCIENTIFIC, INC: TOTAL REVENUE AND RandD EXPENSES (2012-2014) ($MN) 295
TABLE 91 THERMO FISHER SCIENTIFIC, INC : TOTAL REVENUE, BY SEGMENTS (2012-2014) ($MN) 296
TABLE 92 THERMO FISHER SCIENTIFIC, INC: TOTAL REVENUE, BY GEOGRAPHY (2012-2014) ($MN) 297














LIST OF FIGURES

FIGURE 1 GLOBAL 3D CELL CULTURE MARKET SHARE AND REVENUE, BY REGION, (2013-2021) ($MN) 27
FIGURE 2 3D CELL CULTURE MARKET: RESEARCH APPROACH 35
FIGURE 3 3D CELL CULTURE MARKET: TOP-DOWN AND BOTTOM-UP APPROACH 36
FIGURE 4 3D CELL CULTURE MARKET: FORECASTING MODEL 37
FIGURE 5 3D CELL CULTURE MARKET: MARKET CRACKDOWN AND DATA TRIANGULATION 38
FIGURE 6 3D CELL CULTURE GLOBAL MARKET: MARKET SEGMENTATION 45
FIGURE 7 MARKET DYNAMICS 46
FIGURE 8 3D CELL CULTURE MARKET: PORTER'S ANALYSIS 64
FIGURE 9 3D CELL CULTURE GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2014 67
FIGURE 10 3D CELL CULTURE GLOBAL MARKET REVENUE, BY TYPE (2013-2021) ($MN) 72
FIGURE 11 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET SHARE, BY TYPE,
(2014 V'S 2021) (%) 76
FIGURE 12 SCAFFOLD BASED PLATFORMS GLOBAL MARKET SIZE, BY TYPE (2014) (%) 79
FIGURE 13 SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY TYPE, (2014) ($MN) 101
FIGURE 14 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY TYPE, (2014 V'S 2021) ($MN) 123
FIGURE 15 3D CELL CULTURE GLOBAL MARKET REVENUE, BY APPLICATION (2014) (%) 136
FIGURE 16 3D CELL CULTURE GLOBAL MARKET REVENUE, BY END-USERS (2013-2021) ($MN) 153
FIGURE 17 3D CELL CULTURE GLOBAL MARKET REVENUE, BY REGION (2013-2021) ($MN) 163
FIGURE 18 NORTH AMERICAN 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION and END-USERS (2014 V'S 2021) ($MN) 166
FIGURE 19 EUROPEAN 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION and END-USERS (2014 V'S 2021) ($MN) 176
FIGURE 20 ASIA-PACIFIC 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION and END-USERS (2014 V'S2021) ($MN) 186
FIGURE 21 REST OF THE WORLD 3D CELL CULTURE MARKET REVENUE, BY TECHNOLOGY, CONSUMABLES, APPLICATION and END-USERS (2014 V'S 2021) ($MN) 196
FIGURE 22 KEY GROWTH STRATEGIES, (2013 - 2015) 206
FIGURE 23 SWOT: 3D BIOMATRIX 228
FIGURE 24 SWOT: 3D BIOTEK 232
FIGURE 25 SWOT: BECTON, DICKINSON AND COMPANY 240
FIGURE 26 SWOT: CORNING INCORPORATED 249
FIGURE 27 SWOT: GLOBAL CELL SOLUTIONS 253
FIGURE 28 SWOT: INSPHERO AG 260
FIGURE 29 SWOT: LONZA GROUP 270
FIGURE 30 SWOT: NANO 3D BIOSCIENCES 275
FIGURE 31 SWOT: NANOFIBER SOLUTION 279
FIGURE 32 SWOT: REPROCELL 284
FIGURE 33 SWOT: SIGMA ALDRICH 293
FIGURE 34 SWOT: THERMO FISHER SCIENTIFIC, INC 303

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