Drug and Medication Industry: The Christie NHS Foundation Trust – Developmental Therapeutics Review – Q4 2010

• Publication date: December 2010

The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects. This report is built using data and information sourced from Global Industry s Direct’s proprietary databases, Firms ’s corporate website, SEC filings, investor presentations and featured press releases, both from industry player and market -specific third party sources, put together by G...

The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects.

This report is built using data and information sourced from Global Industry s Direct’s proprietary databases, Firms ’s corporate website, SEC filings, investor presentations and featured press releases, both from industry player and market -specific third party sources, put together by Global Industry s Direct’s team.

Scope of the Research

- The Christie NHS Foundation Trust - Brief industry player overview including business description, key information and facts, and its locations and subsidiaries.
- Review of current pipeline of The Christie NHS Foundation Trust human therapeutic division.
- Detailed Analysis of pipeline therapeutics across various therapy areas.
- Coverage of current pipeline molecules in various stages of drug development, including the combination treatment modalities, across the globe.
- Product profiles for late stage and clinical stage products of The Christie NHS Foundation Trust with complete description of the product’s developmental history, mechanism of action, therapeutic class, target and major milestones.
- Recent updates of the The Christie NHS Foundation Trust’s pipeline in the last quarter.
- Key discontinued and dormant projects.
- Latest news and deals relating to the products.

Why Should You Get This Report?

- Evaluate The Christie NHS Foundation Trust’s strategic position with total access to detailed information on its product pipeline.
- Assess the growth potential of The Christie NHS Foundation Trust in its therapy areas of focus.
- Identify new drug targets and therapeutic classes in the The Christie NHS Foundation Trust’s Research and Development portfolio and develop key strategic initiatives to reinforce pipeline in those areas.
- Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps.
- Exploit collaboration and partnership opportunities with The Christie NHS Foundation Trust.
- Avoid Intellectual Property Rights related issues.
- Explore the dormant and discontinued projects of The Christie NHS Foundation Trust and identify potential opportunities in those areas.

Global Therapy Industry

Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 4
The Christie NHS Foundation Trust Snapshot 5
The Christie NHS Foundation Trust Overview 5
Key Information 5
Key Facts 5
The Christie NHS Foundation Trust – Research and Development Overview 6
Key Therapeutic Areas 6
The Christie NHS Foundation Trust – Pipeline Review 9
Pipeline Products by Stage of Development 9
Pipeline Products – Monotherapy 10
Pipeline Products – Combination Treatment Modalities 11
The Christie NHS Foundation Trust – Pipeline Products Glance 12
The Christie NHS Foundation Trust – Late Stage Pipeline 12
Phase III Products/Combination Treatment Modalities 12
The Christie NHS Foundation Trust Clinical Stage Pipeline Products 13
Phase II Products/Combination Treatment Modalities 13
The Christie NHS Foundation Trust – Drug Profiles 14
cisplatin + etoposide 14
Product Description 14
Mechanism of Action 14
R&D Progress 14
Cisplatin + Etoposide + Radiation Therapy 15
Product Description 15
Mechanism of Action 15
R&D Progress 15
Epirubicin + Cisplatin + 5-Flourouracil 17
Product Description 17
Mechanism of Action 17
R&D Progress 17
Gemcitabine + Carboplatin 18
Product Description 18
Mechanism of Action 18
R&D Progress 18
Gemcitabine + Cisplatin 19
Product Description 19
Mechanism of Action 19
R&D Progress 19
Gemcitabine Hydrochloride 20
Product Description 20
Mechanism of Action 20
R&D Progress 20
Paclitaxel + Carboplatin 21
Product Description 21
Mechanism of Action 21
R&D Progress 21
Vincristine + Adriamycin + Cyclophosphamide 22
Product Description 22
Mechanism of Action 22
R&D Progress 23
Aldesleukin + Maxamine 24
Product Description 24
Mechanism of Action 24
R&D Progress 24
Bevacizumab 25
Product Description 25
Mechanism of Action 25
R&D Progress 25
Cetuximab + Radiation Therapy 26
Product Description 26
Mechanism of Action 26
R&D Progress 26
Irinotecan + 5-Fluorouracil + Radiation Therapy 27
Product Description 27
Mechanism of Action 27
R&D Progress 27
Mitomycin C + Capecitabine 28
Product Description 28
Mechanism of Action 28
R&D Progress 28
Temozolomide 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
The Christie NHS Foundation Trust – Pipeline Analysis 30
The Christie NHS Foundation Trust – Pipeline Products by Therapeutic Class 30
The Christie NHS Foundation Trust Pipeline Products By Target 32
The Christie NHS Foundation Trust – Pipeline Products by Route of Administration 34
The Christie NHS Foundation Trust – Pipeline Products by Molecule Type 35
The Christie NHS Foundation Trust – Locations And Subsidiaries 36
Head Office 36
Appendix 37
Methodology 37
Coverage 37
Secondary Research 37
Primary Research 37
Expert Panel Validation 38
Contact Us 38
Disclaimer 38List of Tables
The Christie NHS Foundation Trust – Pipeline by Therapy Area and Indication, 2010 8
The Christie NHS Foundation Trust – Pipeline by Stage of Development, 2010 9
The Christie NHS Foundation Trust – Monotherapy Products in Pipeline, 2010 10
The Christie NHS Foundation Trust – Combination Treatment Modalities in Pipeline, 2010 11
The Christie NHS Foundation Trust – Phase III, 2010 12
The Christie NHS Foundation Trust - Phase II, 2010 13
The Christie NHS Foundation Trust - Pipeline By Therapeutic Class, 2010 30
The Christie NHS Foundation Trust - Pipeline By Target, 2010 33
The Christie NHS Foundation Trust – Pipeline By Route of Administration, 2010 34
The Christie NHS Foundation Trust – Pipeline By Molecule Type, 2010 35

List of Figures
The Christie NHS Foundation Trust – Pipeline by Therapy Area and Indication, 2010 7
The Christie NHS Foundation Trust – Pipeline by Stage of Development, 2010 9
The Christie NHS Foundation Trust – Monotherapy Products in Pipeline, 2010 10
The Christie NHS Foundation Trust – Combination Treatment Modalities in Pipeline, 2010 11
The Christie NHS Foundation Trust – Pipeline By Therapeutic Class, 2010 30
The Christie NHS Foundation Trust - Pipeline By Target, 2010 32
The Christie NHS Foundation Trust – Pipeline By Route of Administration, 2010 34
The Christie NHS Foundation Trust – Pipeline By Molecule Type, 2010 35