Drug delivery is evolving at a rapid rate with new drug product formulations being discovered frequently. Advanced drug delivery deals with developing solutions for new entities in therapeutic pharmacology such as protein and peptides and other novel compounds targeting drugs to specific disease sites including gene therapy. Treatments for chronic conditions and growth in patient-administered drugs are factors leading to greater focus on ease-of-use and convenience.

Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies) details the types of drug delivery systems, technologies and products utilizing advanced drug delivery systems The report describes the industry, its relationship to various healthcare channels, and the trends for the future.


The advanced drug delivery market is two-fold. First of all it identifies drug delivery technology Secondly, it identifies products in the pharmaceutical arena that utilize those drug delivery technologies. Because drug delivery technology is an integral part of sales of pharmaceuticals and drug delivery technology cannot exist without pharmaceuticals, revenues have been reported that include pharmaceutical sales. This report will provide market data that includes the pharmaceutical revenues of those products that utilize advanced drug delivery.

In this report, the advanced drug delivery market is divided into three main segments and market estimates are provided for indications within each category:

  • Liposome Drug Delivery (by Indication - Fungal Infections Cancer, Others)

  • Polymer Drug Delivery (by Indication - Cancer, Neutropenia, Hepatitis, Contraception, Schizophrenia, Acromegaly and Others)

  • Monoclonal Antibodies Drug Delivery (by Indication - Arthritis, Cancer, Multiple Sclerosis, Macular Degeneration, Respiratory Syncytial Virus, Others)


The following types of polymer delivery drugs are segmented within this report.

  • PEGylated Delivery

  • Emulsuion Delivery

  • Injectable Delivery

  • Nanoparticle Delivery

  • Others


A wide range of trends and issues that will impact the advance drug delivery market are discussed in the report including the current state of biotechnolgy expansion, molecular imprinted polymers, hot-melt extrusion, metallofullerenes, nanotechnology advancements and other emerging Drug Delivery technologies not yet on the market.



The following companies are profiled in the report:

  • Alkermes, Inc.

  • ALZA Corporation

  • AP Pharma

  • Centocor Ortho Biotech, Inc.

  • Eisai , Inc

  • Elan Corporation, Plc

  • EnColl Corporation, Inc.

  • Enzon Pharmaceuticals, Inc

  • Gilead Sciences, Inc.

  • Nektar Therapeutics

  • PDL BioPharma

  • pSivida Corp

  • SurModics, Inc

  • Tolmar, Inc


The research conducted by Kalorama Information included comprehensive research of primary and secondary sources such as interviews with company executives, company literature, databases, investment reports, and medical and business journals. New technologies, market developments, and research and development trends and expenditures were identified through patent and data-based searches, as well as via interviews with key personnel. Person-to-person and telephone interviews were the primary method of gathering information. E-mail correspondence was also used in the interview process. Interviews with 24 key industry officials, trade association spokespersons, consultants, healthcare providers, and government personnel were compiled to form the primary basis of information - particularly revenue and market share data- presented in this report.


All market data pertains to the worldwide market at the manufacturers’ level and was measured in U.S. dollars. The base year for data was 2010. Historical data are provided for 2006 through 2009, with forecast data provided for 2010 through 2014. Compound annual growth rates (CAGR) are provided for the 2006-2010, 2010-2014 and 2006-2014.

Table Of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

Overview

Market Drivers

Market Size and Growth

Market Trends

CHAPTER TWO: INTRODUCTION AND OVERVIEW

Introduction

Scope and Methodology

Reasons for Advanced Drug Delivery Systems

Phases of Drug Action

CHAPTER THREE: LIPOSOME DRUG DELIVERY

Overview

Liposome Targeting

Passive Targeting

Active Targeting

New Developments

Market Summary

Liposome Market by Indication

Liposome Market Competitive Analysis

CHAPTER FOUR: POLYMER DRUG DELIVERY

Overview

Polymeric Implants

Biodegradable Polymers

Nano- and Microparticulates

Polymer Micelles

PEGylation Technology

Hydrogel Polymers

Colloidal systems

PLA, PLG, and PLGA

Emulsions

Proteinaceous microparticles

New Developments

Market Summary

Market for Polymers by Product Type

Polymer Market by Indication

Polymer Market Competitive Analysis

CHAPTER FIVE: MONOCLONAL ANTIBODY DRUG DELIVERY

Overview

New Developments

Market Summary

Monoclonal Antibody Market by Indication

Monoclonal Antibody Market Competitive Analysis

CHAPTER SIX: TRENDS AND TECHNOLOGY DEVELOPMENTS

Expansion of Biotechnology

Incorporation of Technology

Molecular Imprinted Polymers

Antibiotic Biodegradable Implants

Hot-melt Extrusion Technology

Sorbent Technology

Gene Therapy Drug Delivery

Metallofullerenes

Antisense Delivery Systems

Nanotechnology advancements

Camouflaged Nanoparticles

Triggerable Drug Delivery

Prodrug Drug Delivery

Single Chain Antigen-Binding Protein Technology

Heat Shock Protein Technology

Other Emerging Drug Delivery Technologies

CHAPTER SEVEN: MARKET SIZE AND GROWTH

Total Market Summary

Geogrpahical Market Growth Summary Competitive Growth Analysis

CHAPTER EIGHT: COMPANY PROFILES

Alkermes, Inc.

ALZA Corporation

AP Pharma

Centocor Ortho Biotech, Inc.

Eisai , Inc

Elan Corporation, Plc

EnColl Corporation, Inc.

Enzon Pharmaceuticals, Inc

Gilead Sciences, Inc.

Nektar Therapeutics

PDL BioPharma

pSivida Corp

SurModics, Inc

Tolmar, Inc

APPENDIX: COMPANY DIRECTORY




LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Table 1-1: The Global Market for Advanced Drug Delivery 2006-2014

Figure 1-1: The Global Market for Advanced Drug Delivery 2006-2014

CHAPTER TWO: INTRODUCTION AND OVERVIEW

Table 2-1: Sequence of Drug Action

CHAPTER THREE: LIPOSOME DRUG DELIVERY

Table 3-1: Marketed Liposome Drugs, as of October 2010

Table 3-2: New Developments in Liposome Drugs

Table 3-3: The Global Market for Liposomes 2006-2014

Figure 3-1: The Global Market for Liposomes 2006-2014

Table 3-4: The Global Market for Liposomes by Indication, 2006-2010

Figure 3-2: The Global Market for Liposomes by Indication, 2006-2010

Figure 3-3: Market for Liposomes by Indication 2006

Figure 3-4: Market for Liposomes by Indication 2010

Table 3-5: Advanced Drug Delivery: Liposome Market—Competitors Revenues and Market Shares 2009

Figure 3-5: Advanced Drug Delivery: Liposome Market—Competitor Market Shares 2009

CHAPTER FOUR: POLYMER DRUG DELIVERY

Table 4-1: Marketed Biodegradable Polymer Drugs, as of October 2010

Table 4-2: Marketed Nano- and Micro-particle Drugs, as of October 2010

Table 4-3: Marketed PEGylated Drugs, as of October 2010

Table 4-4: Marketed Hydrogel Polymer Drugs, as of October 2010

Table 4-5: Marketed Emulsions, as of October 2010

Table 4-6: New Developments in Polymers

Table 4-7: The Global Market for Polymers 2006-2014

Figure 4-1: The Global Market for Polymers 2006-2014

Table 4-8: Market for Polymers by Product Type 2006-2014

Figure 4-2: Market for Polymers by Product Type 2006-2014

Figure 4-3: Market for Polymers by Product Type 2010

Table 4-9: The Global Market for Polymers by Indication, 2006-2010

Figure 4-4: The Global Market for Polymers by Indication, 2006-2010

Figure 4-5: Market for Polymers by Indication 2006

Figure 4-6: Market for Polymers by Indication 2010

Table 4-10: Advanced Drug Delivery: Polymer Market—Competitors Revenues and Market Shares 2009

Figure 4-7: Advanced Drug Delivery: Polymer Market—Competitor Market Shares 2009

CHAPTER FIVE: MONOCLONAL ANTIBODY DRUG DELIVERY

Table 5-1: Key Marketed Monoclonal Antibodies, as of October 2010

Table 5-2: New Developments in Monoclonal Antibodies

Table 5-3: The Global Market for Monoclonal Antibodies 2006-2014

Figure 5-1: The Global Market for Monoclonal Antibodies 2006-2014

Table 5-4: The Global Market for Monoclonal Antibodies by Indication, 2006-2010

Figure 5-2: The Global Market for Monoclonal Antibodies by Indication, 2006-2010

Figure 5-3: Market for Monoclonal Antibodies by Indication 2006

Figure 5-4: Market for Monoclonal Antibodies by Indication 2010

Table 5-5: Advanced Drug Delivery: Monoclonal Antibody Market—Competitors Revenues and Market Shares 2009

Figure 5-5: 108 Advanced Drug Delivery: Monoclonal Antibody Market—Competitor Market Shares 2009

CHAPTER SIX: TRENDS AND TECHNOLOGY DEVELOPMENTS

Table 6-1: Nanotechnology Drug Delivery 2010, Companies and Technology

CHAPTER SEVEN: MARKET SIZE AND GROWTH

Table 7-1: The Worldwide Market for Advanced Drug Delivery Systems Revenues by Type 2006-2014

Figure 7-1: 1 The Worldwide Market for Advanced Drug Delivery Systems Revenues by Type 2006-2014

Table 7-2: The Worldwide Market for Advanced Drug Delivery Systems Market Share by Type 2006-2014

Figure 7-2: The Worldwide Market for Advanced Drug Delivery Systems Share by Type 2006

Figure 7-3: The Worldwide Market for Advanced Drug Delivery Systems Share by Type 2010

Figure 7-4: The Worldwide Market for Advanced Drug Delivery Systems Share by Type 2014

Table 7-3: Worldwide Advanced Drug Delivery by Geographical Region, 2006-2010

Figure 7-5: Worldwide Advanced Drug Delivery by Geographical Region, Sales by Region, 2006-2010

Figure 7-6: Worldwide Advanced Drug Delivery by Geographical Region, Percent Sales by Region 2006

Figure 7-7: Worldwide Advanced Drug Delivery by Geographical Region, Percent Sales by Region 2010

Table 7-4: Worldwide Market for Advanced Drug Delivery System Revenues and Market Share by Supplier 2009

Figure 7-8: Worldwide Market for Advanced Drug Delivery Systems Market Share by Leading Supplier 2009

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