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Combination Antibody Therapy for Cancer Treatment

  • January 2016
  • 116 pages
  • Insight Pharma Reports
Report ID: 3588421

Summary

Table of Contents

Recombinant antibodies have been the shining jewels in the firmament of the pharma industry for almost the last two decades. They have returned billions of dollars in sales, and if their performance has not been the unalloyed triumph that was foreseen at their inception, they have, at least in some instances, produced impressive gains in patient response. Today they are one of the most fundamental strategies for treating patients with hematological malignancies and solid tumors. This report explores the next level of therapy, combining antibodies with additional agents.

The report consists of eight chapters that address different aspects of the issue of combined antibody therapy – past, present, and future, topics include:

A brief review of the clinical efficacy and market status of currently approved antibody-based drugs for cancer therapy
Outlook for combination antibody therapeutics
Targeted Antibody Therapeutics & Immuno-Antibody Therapeutics
Development and Current Products
Combination of Chemotherapy and Immuno-antibody therapeutics
Combinations of immune-antibodies
Immuno- antibody therapeutics in the marketplace
Fusion Antibody Therapeutics
Multitargeted and Polyfunctional Antibody Therapeutics
Patent Expiration and the Rise of Biosimilars
Biosimilar antibodies in the market
Deals and the Marketplace
Interviews with Leading Experts:
Interview with Esper Boel, SVP, head of discovery; Ivan Horak, CSO; and Mads Laustsen, CMO at Symphogen
Interview with Eric S. Langer, Managing Partner, BioPlan Associates, Inc.
Interview with Dr. Laurent Ducry, Group Leader Bioconjugates R&D, Lonza, Valais, Switzerland
Interview with Dr. Cheng Liu, CEO, Eureka Therapeutics
Interview with Steve King, President, Peregrine Pharma
Survey with data from Industry Representatives Concerning Developments in Antibody Technology

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