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  4. > Global Non-Invasive Prenatal Testing Market Size, Share, Development, Growth and Demand Forecast to 2020 - Industry Insights by Test Type

The global non-invasive prenatal testing (NIPT) market was valued at $563.4 million in 2014, and it is expected to grow with a CAGR of 17.6% during the period 2015 - 2020. Among the various test types, the MaterniT21 PLUS accounted for the highest share in global NIPT market in 2014. The NIPT market is experiencing significant growth rate due to favourable macro-economic factors, such as increasing healthcare expenditure. The increasing average maternal age and increasing incidence of chromosome syndrome require early and non-invasive fetal testing procedure. This in turn, increases the usage of NIPT to provide early detection of syndromes.

Prenatal tests are medical tests performed during the pregnancy, to determine the development of fetus. Non-invasive prenatal testing (NIPT) is highly sensitive screening method for detecting specific chromosomal abnormalities, such as Patau syndrome (Trisomy13), Down syndrome (Trisomy 21), Turner Syndrome (monosomy x), and Edwards syndrome (Trisomy 18), in the developing baby, from as early as week 10 of pregnancy. NIPT market in developing economies, such as Asia-Pacific, Africa, and Latin America, have been growing with a significant pace due to growing awareness for chromosome syndrome, large women population preferring late pregnancy, and increasing acceptance of these tests.

MaterniT21 PLUS is used to detect fetal chromosomal abnormalities, such as Trisomy 21, Trisomy 18 and Trisomy 13, Trisomy 16 and Trisomy 22; and selected microdeletions, such as 22q (DiGeorge syndrome), 4p (Wolf-Hirschhorn syndrome), 8q (Langer-Giedion syndrome), 11q (Jacobsen syndrome), and 1q36 deletion syndrome. It was the first test introduced in the market for the diagnosis of Trisomy 21, in 2011. The test uses cell-free DNA technology and immensely parallel sequencing, in order to provide patient with unique genetic facts non-invasively. The test provides its results in 5 days from the arrival of blood sample. The MartinT21 PLUS test dominates the global NIPT market in 2014.

The increasing average maternal age and growing demand for early and non-invasive prenatal testing procedure are the factors driving the growth of the market. The maternal age plays a major role in the wide range of birth outcomes, such as birth defects, birth weight, and multiple births. For instance, according to the Centre for Disease Control and Prevention (CDC), the mean age of mother at first birth has increased from 25.8 years in 2012 to 26 years in 2013. In addition, the advancement of developments in assisted reproductive technologies, such as egg donation and in-vitro fertilization (IVF), also increases the incidence of pregnancies within women in the advanced maternal age. The increasing incidence of chromosome syndrome and increasing healthcare expenditure are also fueling the growth of the market. According to CDC, in the U.S. about 6,000 babies are born with Down syndrome, i.e., approximately 1 in every 700 babies is born with the syndrome.

The restraints associated with NIPT market include strict regulatory requirements and ethical hurdles. Some of the ethical concerns associated with NIPT are misuse of NIPT for minor conditions, accessibility and affordability, permissibly legalizing termination of pregnancy due to disability or any other undesired conditions, and others.

The key companies operating in the global non-invasive prenatal testing market include Sequenom Inc., BGI, LifeCodexx AG, Quest Diagnostics Incorporated, Hoffmann-La Roche Ltd., Illumina Inc., Berry Genomics Co., Ltd., Laboratory Corporation of America Holdings and Natera Inc.



Report Coverage

Provides comprehensive understanding of the market with the help of informed market outlook, opportunities, challenges, trends, size and growth, competitive analysis, major competitors and Porter analysis
Identifies the key drivers of growth and challenges of the key industry players. Also, assesses the future impact of the propellants and restraints on the market
Uncovers potential demands in the market
Porter analysis identifies competitive forces within the market
Provides information on the historical and current market size and the future potential of the market
Provides sizes of key regional markets using yardsticks of processes, segments, products, end user and technology, etc (as applicable)
Highlights the competitive scenario of the market, major competitors, market share, benchmarking, investments and merger & acquisitions
Provides profiles of major competitors of the market including details of their operations, product and services, recent developments and key financial metrics. Profiles provide better understanding of competition as well as the demands of the market.

Table Of Contents

Global Non-Invasive Prenatal Testing Market Size, Share, Development, Growth and Demand Forecast to 2020 - Industry Insights by Test Type
Chapter 1. Research Scope and Methodology

1.1 Market Definition

1.2 Market Scope

1.2.1 Global NIPT market breakdown by test type

1.2.2 Global NIPT market breakdown by geography

1.3 Research Methodology and Sources

Chapter 2. Executive Summary

2.1 Key Findings

2.2 Research Summary

Chapter 3. Market Outlook

3.1 Introduction

3.2 Trends in the Market

3.2.1 Increasing number of collaborations and partnerships

3.3 Opportunities in the Market

3.3.1 Emerging markets offer opportunities for non-invasive prenatal testing manufacturers

3.4 Factors Driving the Market and its Impact on Market Forecast

3.4.1 Increasing average maternal age

3.4.2 Increasing incidence rate of chromosome syndromes

3.4.3 Increasing demand for early and non-invasive fetal testing procedures

3.4.4 Increasing healthcare expenditure

3.4.5 Impact analysis of drivers on market forecast

3.5 Factors Hindering the Market and its Impact on Market Forecast

3.5.1 Stringent regulatory requirements

3.5.2 Ethical hurdles

3.5.3 Impact analysis of restraints on market forecast

Chapter 4. Global Non-invasive Prenatal Testing Market Size and Forecast (2014 - 2020)

4.1 Global NIPT Market Breakdown by Test Type

4.2 Global NIPT Market Breakdown by Region

Chapter 5. Global Non-invasive Prenatal Testing Market Breakdown by Test Type

5.1 MaterniT21 PLUS Test Market

5.2 NIFTY Test Market

5.3 Harmony Test Market

5.4 Panorama Test Market

5.5 Verifi Test Market

5.6 PrenaTest Market

Chapter 6. Non-invasive Prenatal Testing Market Breakdown by Geography

6.1 North America NIPT Market

6.1.1 North America NIPT market breakdown by test type

6.1.2 North America NIPT market breakdown by country

6.2 Europe NIPT Market

6.2.1 Europe NIPT market breakdown by test type

6.2.2 Europe NIPT market breakdown by country

6.3 Asia-Pacific NIPT Market

6.3.1 Asia-Pacific NIPT market breakdown by test type

6.3.2 Asia-Pacific NIPT market breakdown by country

6.4 Rest of the World (RoW) NIPT Market

6.4.1 RoW NIPT market breakdown by test type

Chapter 7. Competitive Analysis

7.1 Porter's Five Forces of Competitive Position Analysis

7.1.1 Bargaining power of buyers

7.1.2 Bargaining power of suppliers

7.1.3 Threat of new entrants

7.1.4 Intensity of rivalry

7.1.5 Threat of substitutes

7.2 Competitive Positioning of Major Players

7.2.1 Product differentiation analysis

7.2.2 Geographic presence analysis

7.2.3 Competitive positioning

Chapter 8. Company Profiles and Strategic Developments

8.1 Key Company Profiles

8.1.1 Hoffmann-La Roche Ltd

8.1.1.1 Business overview

8.1.1.2 Product and service offerings

8.1.2 Sequenom Inc.

8.1.2.1 Business overview

8.1.2.2 Product and service offerings

8.1.3 Quest Diagnostics Incorporated

8.1.3.1 Business overview

8.1.3.2 Product and service offerings

8.1.4 Illumina Inc.

8.1.4.1 Business overview

8.1.4.2 Product and service offerings

8.1.5 Laboratory Corporation of America Holdings

8.1.5.1 Business overview

8.1.5.2 Product and service offerings

8.1.6 Berry Genomics Co., Ltd.

8.1.6.1 Business overview

8.1.6.2 Product and service offerings

8.1.7 BGI

8.1.7.1 Business overview

8.1.7.2 Product and service offerings

8.1.8 LifeCodexx AG

8.1.8.1 Business overview

8.1.8.2 Product and service offerings

8.1.9 Natera, Inc.

8.1.9.1 Business overview

8.1.9.2 Product and service offerings

8.2 Strategic Developments in the NIPT Market

8.2.1 Mergers and acquisitions

8.2.2 Collaborations and partnerships

8.2.3 Product approval/ launch

8.2.4 Other developments

Chapter 9. Appendix

9.1 List of Abbreviations





LIST OF TABLES



TABLE 1 SPECIFIC PRIMARY AND SECONDARY SOURCES USED FOR THIS PUBLICATION

TABLE 2 GLOBAL NIPT MARKET SNAPSHOT

TABLE 3 MAJOR COLLABORATIONS AND PARTNERSHIPS IN THE NIPT MARKET

TABLE 4 RISK OF DOWN SYNDROME AND CHROMOSOMAL ABNORMALITIES AT LIVE BIRTH

TABLE 5 HEALTHCARE EXPENDITURE AS % OF GDP

TABLE 6 DRIVERS FOR THE MARKET: IMPACT ANALYSIS

TABLE 7 RESTRAINTS FOR THE MARKET: IMPACT ANALYSIS

TABLE 8 GLOBAL NIPT MARKET BREAKDOWN BY TEST TYPE, $M (2015-2020)

TABLE 9 GLOBAL NIPT MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 10 MATERNIT21 PLUS TEST VALIDATION

TABLE 11 GLOBAL MATERNIT21 PLUS TEST MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 12 NIFTY TEST STATISTICS (AS OF 2013)

TABLE 13 GLOBAL NIFTY TEST MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 14 GLOBAL HARMONY TEST MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 15 GLOBAL PANORAMA TEST MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 16 VERIFI TEST PERFORMED IN MOST COMMON CHROMOSOMAL ANEUPLOIDES0

TABLE 17 VERIFI TEST PERFORMED IN MOST COMMON SEX ANEUPLOIDES

TABLE 18 GLOBAL VERIFI TEST MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 19 GLOBAL PRENATEST MARKET BREAKDOWN BY REGION, $M (2015 - 2020)

TABLE 20 AVERAGE AGE OF MOTHER AT FIRST BIRTH, IN U.S.

TABLE 21 NORTH AMERICA NIPT MARKET BREAKDOWN BY TEST TYPE, $M (2015 - 2020)

TABLE 22 NORTH AMERICA NIPT MARKET BREAKDOWN BY COUNTRY, $M (2015 - 2020)

TABLE 23 HEALTHCARE EXPENDITURE AS % OF GDP, OF EUROPEAN COUNTRIES

TABLE 24 EUROPE NIPT MARKET BREAKDOWN BY TEST TYPE, $M (2015 - 2020)

TABLE 25 EUROPE NIPT MARKET BREAKDOWN BY COUNTRY, $M (2015 - 2020)

TABLE 26 HEALTHCARE EXPENDITURE AS % OF GDP, OF ASIA-PACIFIC COUNTRIES

TABLE 27 ASIA-PACIFIC NIPT MARKET BREAKDOWN BY TEST TYPE, $M (2015 - 2020)

TABLE 28 ASIA-PACIFIC NIPT MARKET BREAKDOWN BY COUNTRY, $M (2015 - 2020)

TABLE 29 ROW NIPT MARKET BREAKDOWN BY TEST TYPE, $M (2015 - 2020)

TABLE 30 COMPARISON OF VARIOUS NON-INVASIVE PRENATAL TESTS

TABLE 31 HOFFMANN-LA ROCHE LTD - KEY FACTS

TABLE 32 SEQUENOM INC. - KEY FACTS

TABLE 33 QUEST DIAGNOSTICS INCORPORATED - KEY FACTS

TABLE 34 ILLUMINA INC. - KEY FACTS

TABLE 35 LABORATORY CORPORATION OF AMERICA HOLDINGS - KEY FACTS

TABLE 36 BERRY GENOMICS CO., LTD - KEY FACTS

TABLE 37 BGI- KEY FACTS

TABLE 38 LIFECODEXX AG - KEY FACTS

TABLE 39 NATERA INC. - KEY FACTS

LIST OF FIGURES

FIG 1 MARKET SCOPE FOR GLOBAL NIPT MARKET

FIG 2 RESEARCH METHODOLOGY FOR GLOBAL NIPT MARKET

FIG 3 TYPES OF CHROMOSOMAL ABNORMALITIES

FIG 4 INDICATIONS OF NIPT

FIG 5 PROCEDURE OF NON-INVASIVE PRENATAL TESTING

FIG 6 FERTILITY AND MISCARRIAGE RATES DUE TO MATERNAL AGE

FIG 7 TRISOMIES IN HUMAN

FIG 8 GLOBAL NIPT MARKET SIZE BY TEST TYPE, $M (2014-2020)

FIG 9 GLOBAL NIPT MARKET SHARE, BY TEST TYPE (2014)

FIG 10 GLOBAL NIPT MARKET SIZE BY REGION, $M (2014-2020)

FIG 11 GLOBAL NIPT MARKET SHARE, BY REGION (2014)

FIG 12 GLOBAL MATERNIT21 PLUS TEST MARKET SIZE BY REGION, $M (2014-2020)

FIG 13 GLOBAL NIFTY TEST MARKET SIZE BY REGION, $M (2014-2020)

FIG 14 GLOBAL HARMONY TEST MARKET SIZE BY REGION, $M (2014-2020)

FIG 15 PANORAMA TEST PROCEDURE

FIG 16 GLOBAL PANORAMA TEST MARKET SIZE BY REGION, $M (2014-2020)

FIG 17 GLOBAL VERIFI TEST MARKET SIZE BY REGION, $M (2014-2020)

FIG 18 GLOBAL PRENATEST MARKET SIZE BY REGION, $M (2014-2020)

FIG 19 GLOBAL NIPT MARKET SIZE, BY GEOGRAPHY (2020)

FIG 20 PREVELANCE OF DOWN SYNDROME IN THE U.S.

FIG 21 NORTH AMERICA NIPT MARKET SIZE BY TEST TYPE, $M (2014-2020)

FIG 22 NORTH AMERICA NIPT MARKET SHARE, BY TEST TYPE (2014)

FIG 23 NORTH AMERICA NIPT MARKET SIZE BY COUNTRY, $M (2014-2020)

FIG 24 NORTH AMERICA NIPT MARKET SHARE, BY COUNTRY (2014 AND 2020)

FIG 25 EUROPE NIPT MARKET SIZE BY TEST TYPE, $M (2014-2020)

FIG 26 EUROPE NIPT MARKET SHARE, BY TEST TYPE (2014)

FIG 27 EUROPE NIPT MARKET SIZE BY COUNTRY, $M (2014-2020)

FIG 28 EUROPE NIPT MARKET SHARE, BY COUNTRY (2014)

FIG 29 ASIA-PACIFIC NIPT MARKET SIZE BY TEST TYPE, $M (2014-2020)

FIG 30 ASIA-PACIFIC NIPT MARKET SHARE, BY TEST TYPE (2014)

FIG 31 ASIA-PACIFIC NIPT MARKET SIZE BY COUNTRY, $M (2014-2020)

FIG 32 ASIA-PACIFIC NIPT MARKET SHARE, BY COUNTRY (2014 AND 2020)

FIG 33 ROW NIPT MARKET SIZE BY TEST TYPE, $M (2014-2020)

FIG 34 ROW NIPT MARKET SHARE, BY TEST TYPE (2014)

FIG 35 PORTER'S FIVE FORCES OF COMPETITIVE POSITION ANALYSIS

FIG 36 GLOBAL AVAILABILITY OF NIPT

FIG 37 OMPETITIVE POSITIONING OF MAJOR PLAYERS

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