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Subcutaneous Markets for Biotherapeutics

  • December 2015
  • -
  • Greystone Research Associates

Summary

In recent years, the number of biological drugs in development and reaching the marketplace has increased significantly. The clinical application of these drugs is sometimes limited by a lack of desirable attributes relative to market needs and opportunities. To realize the full therapeutic and commercial potential of biologicals, drug developers and technologists are applying a number of innovative solutions which are aimed at addressing the limitations of biological drugs one by one. Initiatives include formulation techniques, drug processing strategies and subcutaneous injection device design and customization. These technologies are addressing a range of issues that include drug stability, physical properties, drug release profiles and dosing volumes, factors that can directly affect the ability of drugs to be administered subcutaneously.

What You Will Learn

- What are the major limitations holding back the trend toward self administration of biotherapeutic drugs?
- What are the technology initiatives and solutions being applied to biotherapeutic drugs and drug candidates to enable their delivery via subcutaneous injection?
- Who are the important technology suppliers, their capabilities, and their drug development partners?
- What is the market for subcutaneous biotherapeutics today? What will it be in 2022?
- How important are drug developer-technology partner relationships to commercial success?
- What are the essential design factors, technologies and market development issues for increasing the commercial potential of biotherapeutic drugs?
- How are biotherapeutic technology solutions aligned with various drug classes and therapeutic markets?
- What are the significant economic, technology, and regulatory factors affecting subcutaneous biotherapeutics?

Table Of Contents

Subcutaneous Markets for Biotherapeutics
Executive Summary

Therapeutic Biologicals - Challenges and Risks
The Biological Therapeutics Market Space
Drug Properties - Limits and Constraints
Stability
Half?Life and Therapeutic Protocols
Immunogenicity
Dug Viscosities
Drug Volumes
Market Sector Demand Drivers
Diseases and Indications
Patient Population Demographics
Access and Reimbursement
Developing Economies
Biotherapeutics - The Competitive Landscape

Biotherapeutics Administration - Product Strategies
Processing Strategies
Lyophilization
Reconstitution
Dual Chamber Devices
Custom Recon Systems
Third Party Recon Solutions
Formulation Strategies
Hyaluronidase
Extended/Sustained Release
Liposomes
Microspheres
Biodegradable Polymers
Delivery Device Strategies
High Visc Autoinjectors
CoC PFS
Wearable SC Infusion Devices
Large Volume Injectors
Other Device Classes

Subcutaneous Biotherapeutics - The Current Market
Antibodies
Enzymes
Growth Factors
Hematopoietics
Hormones
Immune Modulators
Other Protein Therapy Classes

Biotherapeutic Market Segments - Analysis, Market Data and Forecasts
Antivirals
Autoimmune Diseases
Blood Factors and Hematopoietics
Hormone Replacement
Infectious Diseases
Metabolic Diseases
Neurology
Oncology
Reproductive Health
Respiratory Conditions
Orphan Diseases

Biotherapeutics - Commercialization and Market Factors
Regulatory Factors and Issues
Biosimilars
Managed Care and Healthcare Economics

Company Profiles

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