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  4. > Self Administration of High Viscosity Injectables

Self Administration of High Viscosity Injectables

  • November 2015
  • -
  • Greystone Research Associates

Summary

Growth in biological drugs has been driven by advances in biotechnology and host-vector engineering – advances that have led to a steady stream of biologics for a number of ailments and conditions. These powerful drugs come with a high cost-per-dose and the risk of significant side effects – factors that place an elevated emphasis on administration efficiency, safety and reliability. Many drugs in this class are characterized by physical properties and sensitivities that challenge the drug commercialization ecosystem. For example, monoclonal antibodies, perhaps the most significant category in terms of therapeutic and commercial importance, typically possess viscosities that are well above the normal limits of subcutaneous injection techniques. Drug developers and device designers are increasingly working in collaboration to address the goal of patient self administration of high viscosity injectables.

Self Administration of High Viscosity Injectables – What You Will Learn

- Analyzes the market for therapeutic drugs with viscosities that cannot be delivered using standard patient self-injection devices and techniques
- Assesses technologies and devices that are aimed at positioning high viscosity drugs for patient self-administration, including injection devices and viscosity-lowering formulation techniques
- Analyzes design factors, material selection issues, formulation factors, and device capabilities and limitations
- Profiles injectable drug and device participants, their product development activities, business strategies, and corporate alliances and affiliations
- Evaluates key therapeutic sectors for high viscosity injectables
- Provides market data and forecasts to 2020
- Evaluates the impact of economic, technology, and regulatory factors on self-injecting high viscosity drugs

Table Of Contents

Self Administration of High Viscosity Injectables
Executive Summary

The Market Opportunity

The Economics of Injectable Drugs
Injectable Drug Trends and Market Drivers
Prefilled Devices
Self-Administration
Shifting Demographics
Injector Design Innovation
Therapeutic Demand Drivers
Competitive Landscape
Risk Factors

High Viscosity Injection Devices - Design Factors

Drug Properties (T/C/V)
Drug Storage Requirements
Injection Methodology
Baseline Device Capabilities
Primary Packaging
Lyophilized Drugs/Reconstitution
Human Engineering/Ergonomics
Formulation Technology

High Viscosity Injection - Device Analysis

Specialty Autoinjectors
Plastic Syringes
Wearable Subcutaneous Infusion Devices
Patch-like Devices
Other Device Classes

High Viscosity Injectables - the Current Market

Combination Products
Alliances and Collaborations

High Viscosity Injectables - Key Therapeutic Sector Analysis

Therapy Sectors
Forecasts and Prospects

Market Factors

Regulatory Initiatives
Patient Compliance and Ease of Use
Healthcare Economics

Company Profiles

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