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MediPoint: Extremity Reconstruction - Global Analysis and Market Forecasts

Summary

The global extremity reconstruction market, which covers implant devices for the shoulder, elbow, wrist, digits, and ankle joints, is a billion-dollar market expected to grow through 2021. The growing global aging population, rising prevalence of arthritis, and expanding indications for extremity implant devices, as well as patient preference to maintain an active lifestyle, are expected to drive growth in the extremity replacement market through the forecast period. Emerging extremity implant technologies focus on recreating patient anatomy and natural joint function. Additionally, manufacturers focus on less invasive implant designs to accommodate future revision procedures.

This report examines extremity implant device adoption and challenges faced by current competitors in the 10 major markets (10MM): US, France, Germany, Italy, Spain, UK, Japan, China, India, and Brazil. The analysis also identifies unmet needs in the market, specifies the major drivers and barriers to device adoption, provides insight into marketed and pipeline products, and provides an understanding of physician perception and outlook with an overall emphasis on current and future industry trends in the 10MM.

Highlights

Key Questions Answered

- What is the current and future extremity reconstruction market outlook in the developed and emerging markets? What trends are affecting the global market?
- Which are the key, high growth markets that extremity implant manufacturers should expand into? Which markets are growing the fastest, and what are the top-selling products in each segment?
- What are the unmet needs with extremity reconstruction products currently on the market? How will emerging technologies fulfill these unmet needs?
- What clinical factors and technical specifications influence a physician to use one implant device over another? What is physician perception and market outlook of extremity reconstruction?
- What are the challenges and complications of extremity reconstruction that have hindered widespread adoption?
- With developing the next-generation of extremity implant products, what aspects of the technology are device manufacturers focused on optimizing? How will new entrants impact the global extremity reconstruction market?

Scope

- Annualized total extremity reconstruction market revenue by type of device, direct and indirect costs of disease, procedure trends, and market outlooks by country through 2021.
- Key topics covered include strategic competitor assessment, market characterization, identification of unmet needs, reimbursement and regulatory considerations, evaluating market access in each region covered in the report, and implications of the emerging technologies on the market.
- Pipeline analysis: Comprehensive data split across different stages of development, including a discussion of emerging trends and extremity implant products in development.
- Analysis of the current and future market competition in the global extremity reconstruction market. Insightful review of the key industry drivers, opportunities, barriers and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

- “What Physicians Think” quotes provide a unique insight into how healthcare professionals are reacting to events within the industry, and what their responses could mean for industry strategists. In this report you will understand the perceptions of leading orthopedic surgeons from around the world. This information is essential for all strategic decision makers in every organization allowing them to act on high quality information.

Table Of Contents

MediPoint: Extremity Reconstruction - Global Analysis and Market Forecasts
1 Table of Contents
1 Table of Contents 6
1.1 List of Tables 15
1.2 List of Figures 21
2 Introduction 26
2.1 Catalyst 26
2.2 Related Reports 26
3 Industry Overview 27
3.1 Overview 27
3.2 Procedure Trends 27
3.2.1 Global Overview 27
3.2.2 By Country 28
3.3 Market Access 70
3.3.1 Purchasing Decisions 70
3.3.2 Adoption 71
3.4 Brand Loyalty 74
3.5 Regulation 74
3.5.1 US 75
3.5.2 5EU 76
3.5.3 APAC 78
3.5.4 South America 80
3.6 Reimbursement 81
3.6.1 US 82
3.6.2 5EU 87
3.6.3 APAC 91
3.6.4 South America 94
3.7 Product Recalls 96
3.8 Mergers and Acquisitions 98
3.8.1 Wright Medical Merges with Tornier in $3.3 Billion All-Stock Deal (October 2015) 98
3.8.2 Integra LifeSciences to Acquire Total Ankle Replacement Portfolio from Tornier N.V. (September 2015) 99
3.8.3 Zimmer Acquires Biomet in $13.35 Billion Deal (June 2015) 99
3.8.4 Teijin Acquires Nakashima Medical for JPY 1.5 Billion (April 2015) 100
3.8.5 Stryker Acquires Small Bone Innovations for $375m (August-September 2014) 100
3.8.6 Wright Medical Acquires OrthoPro for $36m (February 2014) 100
3.8.7 Wright Medical Acquires Solana Surgical for $90m (January 2014) 101
3.8.8 Wright Medical Acquires Biotech International for $80m (November 2013) 101
3.8.9 Johnson and Johnson Acquires Synthes for $19.7 Billion (June 2012) 101
3.8.10 Integra LifeSciences Acquires Ascension Orthopedics for $65m (September 2011) 102
3.9 Economic Impact 102
3.9.1 Arthritis 102
3.9.2 High Revision Rates 104
4 Unmet Needs 105
4.1 Shoulder Replacement 105
4.1.1 Durable Glenoid Components 105
4.1.2 Augmented Glenoid Components 107
4.1.3 Grammont-Style Versus Frankle-Style 108
4.1.4 Addressing Complications of Reverse Shoulder Replacement 110
4.1.5 Bone-Sparing Stemless Designs: Pros and Cons 112
4.1.6 Revision Systems 114
4.1.7 Long-Term Follow-Up 116
4.1.8 Patient Awareness in Emerging Markets 116
4.1.9 Accurate Glenoid Component Positioning 117
4.1.10 Implant Sizing for APAC Patients 119
4.2 Elbow Replacement 119
4.2.1 Implant Survival and Fixation Techniques 119
4.2.2 Implant Positioning 121
4.2.3 Long-Term Follow-Up 123
4.3 Wrist Replacement 123
4.3.1 Long-Term Clinical Data 123
4.3.2 Limited Product Offerings 124
4.3.3 Failure and Revision Rates 125
4.3.4 Physiological Wrist Movement 126
4.3.5 Carpal Component Fixation 127
4.4 Digits Replacement 128
4.4.1 Pyrocarbon Implant Durability and Fixation 128
4.4.2 Improved Patient Functionality 129
4.5 Ankle Replacement 130
4.5.1 Long-Term Follow-Up 130
4.5.2 Commitment to Medical Education 131
4.5.3 Advanced Biological Fixation 132
4.5.4 Minimal Bone Resection 134
4.5.5 Mobile-Bearing Versus Fixed-Bearing 135
4.5.6 Bespoke Instrumentation 137
4.5.7 Custom Prostheses 138
4.5.8 Revision Components 139
5 Market Drivers, Barriers, and Opportunities 141
5.1 Driver: Rising Joint Disease Prevalence 141
5.1.1 Sport-Related Injuries 141
5.1.2 Trauma 142
5.1.3 Aging 142
5.1.4 Obesity 142
5.2 Driver: Increased Patient Awareness 143
5.3 Driver: Corporate Promotions and Continuing Medical Education 145
5.4 Driver: Expected Launch of CE-Marked Devices 146
5.5 Driver: Expanded Indications of Reverse Shoulder Replacement 147
5.6 Driver: Stemless Shoulder Implants in the EU 147
5.7 Driver: Superiority of Ankle Replacment over Ankle Fusion 148
5.8 Driver: Expanded Insurance Coverage for TAR 150
5.9 Barrier: Medical Device Excise Tax 150
5.10 Barrier: Postoperative Complications 151
5.11 Barrier: Long Learning Curve 153
5.12 Barrier: Alternatives to Total Joint Replacement 157
5.13 Barrier: Shoulder Replacement Reimbursement 158
5.14 Barrier: Preoperative Patient Selection for TAR 159
5.15 Opportunity: Pyrocarbon 160
5.16 Opportunity: Demand for a Comprehensive Reconstruction Portfolio 161
5.17 Opportunity: Computer-Assisted Navigation and Patient-Specific Instrumentation 162
5.18 Opportunity: Emerging Markets 164
5.19 Opportunity: Capitalizing on Wrist Market Fragmentation 165
5.20 Opportunity: TAR Expanded Indications 165
5.21 Opportunity: Fixed-Bearing TAR Implants in the EU 166
6 Competitive Assessment 168
6.1 Shoulder Replacement 168
6.1.1 Overview 168
6.1.2 Product Profiles - Anatomic Total Shoulder Replacement 169
6.1.3 Product Profiles - Anatomic Stemless Total Shoulder Replacement 195
6.1.4 Product Profiles - Reverse Total Shoulder Replacement 201
6.2 Elbow Replacement 214
6.2.1 Overview 214
6.2.2 Product Profiles 215
6.3 Wrist Replacement 222
6.3.1 Overview 222
6.3.2 Product Profiles 223
6.4 Digits Replacement 230
6.4.1 Overview 230
6.4.2 Product Profiles 232
6.5 Ankle Replacement 232
6.5.1 Overview 232
6.5.2 Product Profiles - Two-Component Fixed-Bearing 233
6.5.3 Product Profiles - Three-Component Mobile-Bearing 239
7 Pipeline Assessment 246
7.1 Overview 246
7.2 Product Profiles 246
7.2.1 AFT Proximal Humerus Fracture Prosthesis (Shoulder Options) 246
7.2.2 Akilos Total Ankle System (Implants International) 247
7.2.3 aSpire Total Shoulder Arthroplasty System (Shoulder Options) 249
7.2.4 Comprehensive Nano Stemless Shoulder (Zimmer Biomet) 250
7.2.5 Helical Conservative Shoulder Prosthesis (University of Missouri) 251
7.2.6 INBONE Calcaneal Stem Implant (Wright Medical) 252
7.2.7 Luna Stemless Humeral Prosthesis (Shoulder Options) 253
7.2.8 PyroCarbon Modular Radial Head (Integra LifeSciences) 254
7.2.9 NDSU Total Ankle Replacement Device (NDSU Research Foundation) 255
7.2.10 Vantage Ankle System (Exactech) 257
8 Clinical Trials to Watch 258
8.1 Overview 258
8.2 Discovery Elbow Long-Term Survivorship Study 258
8.3 Prospective Post Market Clinical Follow-up Study of the Zimmer Trabecular Metal Reverse Shoulder System 259
8.4 An Observational Cohort Study Evaluating the Safety and Performance of Aequalis Resurfacing Head Implant in a Consecutive Series of Patients with Shoulder Arthroplasty 259
8.5 Sidus(TM) Stem-Free Shoulder - A Multi-center, Prospective, Non-controlled Post Market Clinical Follow-up Study 260
8.6 A Prospective, Randomized, Multicenter Study Comparing the Safety and Effectiveness of Arthrex's Eclipse Shoulder Prosthesis to the Univers II Shoulder Prosthesis in Patients with a Degenerative Joint Disease 261
8.7 Prospective Post Market Clinical Follow-Up (PMCF) Study of the Zimmer Trabecular Metal Total Ankle 262
8.8 Motec Versus Remotion Total Wrist Arthroplasty - A Prospective Randomized Study 263
8.9 A Post-market Clinical Follow-up Study of the TITAN Reverse Shoulder System Used in Primary or Revision Total Shoulder Arthroplasty 263
8.10 A Prospective Multi-Center Study of the Safety and Effectiveness of the Tornier Simpliciti Shoulder System in Shoulder Arthroplasty 264
8.11 Retrospective and Prospective Clinical Outcomes Study of the Zimmer Nexel Total Elbow 265
9 Current and Future Players 267
9.1 Overview 267
9.2 Trends in Corporate Strategy 267
9.3 Acumed 268
9.3.1 Overview 268
9.3.2 Portfolio Assessment 269
9.3.3 SWOT Analysis 270
9.4 Arthrex 270
9.4.1 Overview 270
9.4.2 Portfolio Assessment 271
9.4.3 SWOT Analysis 272
9.5 Corin Group 272
9.5.1 Overview 272
9.5.2 Portfolio Assessment 273
9.5.3 SWOT Analysis 274
9.6 DePuy Synthes (Johnson and Johnson) 274
9.6.1 Overview 274
9.6.2 Portfolio Assessment 275
9.6.3 SWOT Analysis 277
9.7 DJO Global 277
9.7.1 Overview 277
9.7.2 Portfolio Assessment 278
9.7.3 SWOT Analysis 280
9.8 Exactech 280
9.8.1 Overview 280
9.8.2 Portfolio Assessment 281
9.8.3 SWOT Analysis 282
9.9 Integra LifeSciences 282
9.9.1 Overview 282
9.9.2 Portfolio Assessment 283
9.9.3 SWOT Analysis 285
9.10 Kyocera Medical Corporation 285
9.10.1 Overview 285
9.10.2 Portfolio Assessment 286
9.10.3 SWOT Analysis 287
9.11 Lima Corporate 287
9.11.1 Overview 287
9.11.2 Portfolio Assessment 288
9.11.3 SWOT Analysis 289
9.12 Smith and Nephew 289
9.12.1 Overview 289
9.12.2 Portfolio Assessment 290
9.12.3 SWOT Analysis 291
9.13 Stryker 291
9.13.1 Overview 291
9.13.2 Portfolio Assessment 292
9.13.3 SWOT Analysis 294
9.14 Tornier 294
9.14.1 Overview 294
9.14.2 Portfolio Assessment 295
9.14.3 SWOT Analysis 297
9.15 Wright Medical Group 297
9.15.1 Overview 297
9.15.2 Portfolio Assessment 298
9.15.3 SWOT Analysis 300
9.16 Zimmer Biomet Holdings 300
9.16.1 Overview 300
9.16.2 Portfolio Assessment 302
9.16.3 SWOT Analysis 303
9.17 Other Players 304
10 Market Outlook 306
10.1 Company Market Share 306
10.1.1 Global Overview 306
10.1.2 By Region 307
10.2 By Market Segment 319
10.2.1 Global Overview 319
10.2.2 By Region 324
10.3 By Geography 327
10.3.1 Global Overview 327
10.3.2 US 331
10.3.3 France 334
10.3.4 Germany 337
10.3.5 Italy 339
10.3.6 Spain 342
10.3.7 UK 345
10.3.8 Japan 347
10.3.9 China 350
10.3.10 India 353
10.3.11 Brazil 357
11 Appendix 360
11.1 Bibliography 360
11.2 Abbreviations 384
11.3 Methodology 389
11.3.1 Overview 389
11.3.2 Coverage 389
11.3.3 Secondary Research 389
11.4 Forecasting Methodology 390
11.5 Physicians and Specialists Included in This Study 391
11.5.1 Key Opinion Leaders 391
11.6 Primary Research Summary 393
11.7 About the Authors 394
11.7.1 Analysts 394
11.7.2 Global Head of Medical Devices 395
11.8 About GlobalData 396
11.9 Disclaimer 396

1.1 List of Tables
Table 1: Global Extremity Replacement Procedure Volumes, 2012-2021 28
Table 2: FDA Classifications - Extremity Joint Implants 76
Table 3: Medicare Coding Guide for Extremity Arthroplasty - 2015 83
Table 4: CPT Coding for Physician Payment in Extremity Arthroplasty - 2015 84
Table 5: Product Recalls (2014-2015) 96
Table 6: Mergers and Acquisitions (2011-2015) 98
Table 7: Direct and Indirect Costs of Arthritis 103
Table 8: Advantages and Disadvantages of Ankle Fusion and Total Ankle Replacement 149
Table 9: Product Profile - Univers II 170
Table 10: Product Profile - Global Advantage 171
Table 11: Product Profile - Global Fx 172
Table 12: Product Profile - Global AP 173
Table 13: Product Profile - Global Unite 174
Table 14: Product Profile - Foundation Shoulder System 175
Table 15: Product Profile - Turon 176
Table 16: Product Profile - Equinoxe 177
Table 17: Product Profile - SEVIIN 178
Table 18: Product Profile - TITAN Modular Shoulder System. 179
Table 19: Product Profile - SMR Modular Shoulder System 180
Table 20: Product Profile - Cofield 2 181
Table 21: Product Profile - Neer 3 182
Table 22: Product Profile - Promos Standard 183
Table 23: Product Profile - Solar Total Shoulder System 184
Table 24: Product Profile - ReUnion HA Fracture System 185
Table 25: Product Profile - Aequalis Primary 186
Table 26: Product Profile - Aequalis Fracture stem 187
Table 27: Product Profile - Affiniti 188
Table 28: Product Profile - Aequalis Ascend 189
Table 29: Product Profile - Ascend Flex Convertible Shoulder System 190
Table 30: Product Profile - Bigliani/Flatow 191
Table 31: Product Profile - Anatomical Shoulder System 192
Table 32: Product Profile - Comprehensive Total Shoulder System 193
Table 33: Product Profile - Comprehensive Fracture System 194
Table 34: Product Profile - Trabecular Metal 195
Table 35: Product Profile - Eclipse 196
Table 36: Product Profile - Simpliciti 197
Table 37: Product Profile - InSpyre 198
Table 38: Product Profile - Comprehensive Nano 199
Table 39: Product Profile - T.E.S.S. Anatomic 200
Table 40: Product Profile - Sidus Stem-Free Shoulder 201
Table 41: Product Profile - Univers Revers Shoulder Prosthesis 202
Table 42: Product Profile - Delta Xtend Reverse Shoulder System 203
Table 43: Product Profile - Reverse Shoulder Prosthesis (RSP) 204
Table 44: Product Profile - Equinoxe Reverse Shoulder System 205
Table 45: Product Profile - SMR Reverse 206
Table 46: Product Profile - Promos Reverse 207
Table 47: Product Profile - ReUnion RSA 208
Table 48: Product Profile - Aequalis Reversed II 209
Table 49: Product Profile - Aequalis Reversed Fracture 210
Table 50: Product Profile - Anatomical Reverse 211
Table 51: Product Profile - T.E.S.S. Reverse 212
Table 52: Product Profile - Comprehensive Reverse Shoulder 213
Table 53: Product Profile - Trabecular Metal Reverse 214
Table 54: Product Profile - Discovery Elbow 216
Table 55: Product Profile - Solar Total Elbow 217
Table 56: Product Profile - Latitude EV 218
Table 57: Product Profile - Coonrad-Morrey 219
Table 58: Product Profile - Nexel 220
Table 59: Other Marketed Elbow Replacement Implants 221
Table 60: Marketed Radial Head Replacement Implants 222
Table 61: Product Profile - Freedom Wrist 224
Table 62: Product Profile - Universal 2 Total Wrist 225
Table 63: Product Profile - ReMotion Total Wrist 226
Table 64: Product Profile - Motec Wrist 227
Table 65: Product Profile - Maestro Total Wrist 228
Table 66: Product Profile - MWP III Total Wrist 229
Table 67: Marketed Finger Digits Implants 232
Table 68: Product Profile - TNK 234
Table 69: Product Profile - Salto Talaris 235
Table 70: Product Profile - INBONE II Total Ankle 237
Table 71: Product Profile - INFINITY Total Ankle System 238
Table 72: Product Profile - Zimmer Trabecular Metal Total Ankle 239
Table 73: Product Profile - Zenith 240
Table 74: Product Profile - HINTEGRA Total Ankle Prosthesis 241
Table 75: Product Profile - BOX 242
Table 76: Product Profile - STAR 243
Table 77: Product Profile - Salto 244
Table 78: Product Profile - CCI Evolution 245
Table 79: Product Profile - AFT Proximal Humerus Fracture Prosthesis 247
Table 80: SWOT Analysis - AFT Proximal Humerus Fracture Prosthesis 247
Table 81: Product Profile - Akilos Total Ankle System 248
Table 82: SWOT Analysis - Akilos Total Ankle System 248
Table 83: Product Profile - aSpire Total Shoulder System 249
Table 84: SWOT Analysis - aSpire Total Shoulder System 249
Table 85: Product Profile - Comprehensive Nano Stemless Shoulder 250
Table 86: SWOT Analysis - Comprehensive Nano Stemless Shoulder 251
Table 87: Product Profile - Helical Conservative Shoulder Prosthesis 252
Table 88: SWOT Analysis - Helical Conservative Shoulder Prosthesis 252
Table 89: Product Profile - INBONE Calcaneal Stem 253
Table 90: SWOT Analysis - INBONE Calcaneal Stem 253
Table 91: Product Profile - Luna 254
Table 92: SWOT Analysis - Luna 254
Table 93: Product Profile - PyroCarbon Modular Radial Head 255
Table 94: SWOT Analysis - PyroCarbon Modular Radial Head 255
Table 95: Product Profile - NDSU Total Ankle Replacement 256
Table 96: SWOT Analysis - NDSU Total Ankle Replacement 256
Table 97: Product Profile - Vantage Ankle System 257
Table 98: Discovery Elbow Long-Term Survivorship Study 258
Table 99: Prospective Post Market Clinical Follow-up Study of the Zimmer Trabecular Metal Reverse Shoulder System 259
Table 100: An Observational Cohort Study Evaluating the Safety and Performance of Aequalis Resurfacing Head Implant in a Consecutive Series of Patients with Shoulder Arthroplasty 260
Table 101: Sidus(TM) Stem-Free Shoulder - A Multi-center, Prospective, Non-controlled Post Market Clinical Follow-up Study 261
Table 102: A Prospective, Randomized, Multicenter Study Comparing the Safety and Effectiveness of Arthrex's Eclipse Shoulder Prosthesis to the Univers II Shoulder Prosthesis in Patients with a Degenerative Joint Disease 262
Table 103: Prospective Post Market Clinical Follow-Up (PMCF) Study of the Zimmer Trabecular Metal Total Ankle 262
Table 104: Motec Versus Remotion Total Wrist Arthroplasty - A Prospective Randomized Study 263
Table 105: A Post-market Clinical Follow-up Study of the TITAN Reverse Shoulder System Used in Primary or Revision Total Shoulder Arthroplasty 264
Table 106: A Prospective Multi-Center Study of the Safety and Effectiveness of the Tornier Simpliciti Shoulder System in Shoulder Arthroplasty 265
Table 107: Retrospective and Prospective Clinical Outcomes Study of the Zimmer Nexel Total Elbow 266
Table 108: Company Profile - Acumed 269
Table 109: SWOT Analysis - Acumed 270
Table 110: Company Profile - Arthrex 271
Table 111: SWOT Analysis - Arthrex 272
Table 112: Company Profile - Corin Group 273
Table 113: SWOT Analysis - Corin Group 274
Table 114: Company Profile - DePuy 275
Table 115: SWOT Analysis - DePuy 277
Table 116: Company Profile - DJO 278
Table 117: SWOT Analysis - DJO 280
Table 118: Company Profile - Exactech 281
Table 119: SWOT Analysis - Exactech 282
Table 120: Company Profile - Integra LifeSciences 283
Table 121: SWOT Analysis - Integra LifeSciences 285
Table 122: Company Profile - KMC 286
Table 123: SWOT Analysis - KMC 287
Table 124: Company Profile - Lima 288
Table 125: SWOT Analysis - Lima 289
Table 126: Company Profile - Smith and Nephew 290
Table 127: SWOT Analysis - Smith and Nephew 291
Table 128: Company Profile - Stryker 292
Table 129: SWOT Analysis - Stryker 294
Table 130: Company Profile - Tornier 295
Table 131: SWOT Analysis - Tornier 297
Table 132: Company Profile - Wright Medical 298
Table 133: SWOT Analysis - Wright Medical 300
Table 134: Company Profile - Zimmer Biomet 301
Table 135: SWOT Analysis - Zimmer Biomet 303
Table 136: Other Players in the Global Extremity Replacement Market 304
Table 137: Global Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 321
Table 138: Global Market Value Forecast by Market Segment for Shoulder Replacement, $m, 2012-2021 323
Table 139: 5EU Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 325
Table 140: APAC Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 327
Table 141: Total Sales Volume by Country for Extremity Replacement Implants, Number of Units, 2012-2021 328
Table 142: Global Market Value Forecast by Country for Extremity Replacement, $m, 2012-2021 330
Table 143: US Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 332
Table 144: France Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 335
Table 145: Germany Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 338
Table 146: Italy Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 340
Table 147: Spain Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 343
Table 148: UK Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 346
Table 149: Japan Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 348
Table 150: China Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 351
Table 151: India Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 355
Table 152: Brazil Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 358

1.2 List of Figures
Figure 1: US Procedure Volume Forecast by Market Segment, 2012-2021 30
Figure 2: US Procedure Volume Comparison by Market Segment, 2014 and 2021 31
Figure 3: US Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 32
Figure 4: US Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 33
Figure 5: France Procedure Volume Forecast by Market Segment, 2012-2021 34
Figure 6: France Procedure Volume Comparison by Market Segment, 2014 and 2021 35
Figure 7: France Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 36
Figure 8: France Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 37
Figure 9: Germany Procedure Volume Forecast by Market Segment, 2012-2021 38
Figure 10: Germany Procedure Volume Comparison by Market Segment, 2014 and 2021 39
Figure 11: Germany Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 40
Figure 12: Germany Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 41
Figure 13: Italy Procedure Volume Forecast by Market Segment, 2012-2021 42
Figure 14: Italy Procedure Volume Comparison by Market Segment, 2014 and 2021 43
Figure 15: Italy Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 44
Figure 16: Italy Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 45
Figure 17: Spain Procedure Volume Forecast by Market Segment, 2012-2021 46
Figure 18: Spain Procedure Volume Comparison by Market Segment, 2014 and 2021 47
Figure 19: Spain Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 48
Figure 20: Spain Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 49
Figure 21: UK Procedure Volume Forecast by Market Segment, 2012-2021 50
Figure 22: UK Procedure Volume Comparison by Market Segment, 2014 and 2021 51
Figure 23: UK Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 52
Figure 24: UK Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 53
Figure 25: Japan Procedure Volume Forecast by Market Segment, 2012-2021 55
Figure 26: Japan Procedure Volume Comparison by Market Segment, 2014 and 2021 56
Figure 27: Japan Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 57
Figure 28: Japan Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 58
Figure 29: China Procedure Volume Forecast by Market Segment, 2012-2021 59
Figure 30: China Procedure Volume Comparison by Market Segment, 2014 and 2021 60
Figure 31: China Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 61
Figure 32: China Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 62
Figure 33: India Procedure Volume Forecast by Market Segment, 2012-2021 63
Figure 34: India Procedure Volume Comparison by Market Segment, 2014 and 2021 64
Figure 35: India Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 65
Figure 36: India Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 66
Figure 37: Brazil Procedure Volume Forecast by Market Segment, 2012-2021 67
Figure 38: Brazil Procedure Volume Comparison by Market Segment, 2014 and 2021 68
Figure 39: Brazil Shoulder Replacement Procedure Volume Forecast by Segment, 2012-2021 69
Figure 40: Brazil Shoulder Replacement Procedure Volume Comparison by Segment, 2014 and 2021 70
Figure 41: Global Company Market Shares for Extremity Replacement, 2014 306
Figure 42: US Company Market Shares for Extremity Replacement, 2014 308
Figure 43: 5EU Company Market Shares for Extremity Replacement, 2014 309
Figure 44: France Company Market Shares for Extremity Replacement, 2014 310
Figure 45: Germany Company Market Shares for Extremity Replacement, 2014 311
Figure 46: Italy Company Market Shares for Extremity Replacement, 2014 312
Figure 47: Spain Company Market Shares for Extremity Replacement, 2014 313
Figure 48: UK Company Market Shares for Extremity Replacement, 2014 314
Figure 49: APAC Company Market Shares for Extremity Replacement, 2014 315
Figure 50: Japan Company Market Shares for Extremity Replacement, 2014 316
Figure 51: China Company Market Shares for Extremity Replacement, 2014 317
Figure 52: India Company Market Shares for Extremity Replacement, 2014 318
Figure 53: Brazil Company Market Shares for Extremity Replacement, 2014 319
Figure 54: Global Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 321
Figure 55: Global Market Value Forecast by Market Segment for Shoulder Replacement, $m, 2012-2021 323
Figure 56: 5EU Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 325
Figure 57: APAC Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 326
Figure 58: Global Sales Volume for Extremity Replacement Implants, Number of Units, 2012-2021 328
Figure 59: Global Market Value Forecast by Country, $m, 2012-2021 329
Figure 60: Global Market Share Comparison by Country, 2014 and 2021 331
Figure 61: US Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 332
Figure 62: US Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 334
Figure 63: France Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 335
Figure 64: France Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 336
Figure 65: Germany Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 337
Figure 66: Germany Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 339
Figure 67: Italy Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 340
Figure 68: Italy Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 342
Figure 69: Spain Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 343
Figure 70: Spain Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 344
Figure 71: UK Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 345
Figure 72: UK Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 347
Figure 73: Japan Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 348
Figure 74: Japan Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 350
Figure 75: China Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 351
Figure 76: China Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 353
Figure 77: India Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 354
Figure 78: India Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 356
Figure 79: Brazil Market Value Forecast by Market Segment for Extremity Replacement, $m, 2012-2021 357
Figure 80: Brazil Market Value Comparison by Market Segment for Extremity Replacement, 2014 and 2021 359
Figure 81: Primary Research Participants by Country 393

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