1. Market Research
  2. > Pharmaceutical Market Trends
  3. > Vital Signs - Lowering Drug Development Costs with Genetically Modified Swine 

Vital Signs - Lowering Drug Development Costs with Genetically Modified Swine 

  • March 2016
  • -
  • Frost & Sullivan
  • -
  • 4 pages

Summary

Table of Contents

Lowering Drug Development Costs with Genetically Modified Swine

The US pharmaceutical industry spends approximately $ billion annually to develop new pharmaceutical drugs and medical devices. Today, a new drug takes approximately years and over $ billion to bring to market.
Then, only one in every to drugs is approved by the Food and Drug Administration (FDA). On average, pre-clinical testing for one drug candidate alone costs $ to $ million. These high costs and long drug development intervals are due, in part, to the use of animal models that are not predictive of how the drugs will perform during subsequent human clinical trials. The use of genetically-modified swine for pre-clinical efficacy and toxicity studies will improve the predictive nature of pre-clinical testing and inevitably lower drug and medical device development costs. As a result, patients will receive needed medications faster and more affordably.

Pre-clinical tests involve translational research in which medical devices and/or pharmaceutical products are tested on animals. In these studies, animals are used that express symptoms similar to those found in humans and the results are extrapolated to predict the probability of success when tested in humans. Yet, the predictive ability of animal trials is limited. In many cases, the animals do not have the exact same diseases as those found in humans, but instead are induced to express physiological symptoms similar to those found in humans.

Product development costs could be greatly reduced by using animal models that more closely resemble humans in their disease states and their physiological responses to treatment. Swine have been increasingly used as the animal model of choice because their anatomy, genetics, and physiology are more similar to humans than traditional animal models such as mice (Bendixen et al., 2010).

Get Industry Insights. Simply.

  • Latest reports & slideshows with insights from top research analysts
  • 24 Million searchable statistics with tables, figures & datasets
  • More than 10,000 trusted sources
Get This Report
24/7 Customer Support

Talk to Ahmad

+1 718 618 4302

Purchase Reports From Reputable Market Research Publishers
PharmaPoint: Psoriatic Arthritis - Global Drug Forecast and Market Analysis to 2025

PharmaPoint: Psoriatic Arthritis - Global Drug Forecast and Market Analysis to 2025

  • $ 10995
  • Industry report
  • December 2016
  • by GlobalData

PharmaPoint: Psoriatic Arthritis - Global Drug Forecast and Market Analysis to 2025 Summary Psoriatic arthritis (PsA) is a chronic immune-mediated arthritis typically affecting the large joints, especially ...

PharmaPoint: Dyslipidemia - Global Drug Forecast and Market Analysis to 2025

PharmaPoint: Dyslipidemia - Global Drug Forecast and Market Analysis to 2025

  • $ 10995
  • Industry report
  • December 2016
  • by GlobalData

PharmaPoint: Dyslipidemia - Global Drug Forecast and Market Analysis to 2025 Summary Sales of dyslipidemia therapeutics is estimated to be approximately $11.2B across the 7MM in 2015, encompassing the ...

PharmaFocus: Tauopathies - Global Market Analysis

PharmaFocus: Tauopathies - Global Market Analysis

  • $ 9495
  • Industry report
  • February 2017
  • by GlobalData

PharmaFocus: Tauopathies - Global Market Analysis Summary Tauopathies are a class of more than 20 neurodegenerative diseases characterized by tau protein aggregation in the brain. There are currently no ...


ref:plp2016

Reportlinker.com © Copyright 2017. All rights reserved.

ReportLinker simplifies how Analysts and Decision Makers get industry data for their business.