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European Markets for Orthopedic Biomaterials 2011 – Bone Grafting and Hyaluronic Acid Viscosupplementation (15 Countries)

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European Markets for Orthopedic Biomaterials 2011 – Bone Grafting and Hyaluronic Acid Viscosupplementation (15 Countries)

Publication date: May 2011

Keywords : orthopedic biomaterials, bone cement, hyaluronic acid viscosupplementation, orthopedic biomaterial, viscosupplement

The European orthopedic biomaterials markets are expected to approach €1 billion by 2017, with hyaluronic acid viscosupplementation as the largest segment. The European orthopedic biomaterials markets include: - autologous bone grafts, - bone graft substitutes (BGS; segmented into allografts, demineralized bone matrices and synthetics), - hyaluronic acid (HA) viscosupplementation, - bone morphogenetic p...

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TABLE OF CONTENTS

TABLE OF CONTENTS...I
LIST OF FIGURES.V
LIST OF CHARTS....XV
EXECUTIVE SUMMARY.... 1
1.1 TOTAL EUROPEAN ORTHOPEDIC BIOMATERIALS MARKETS 1
1.2 AUTOGRAFTED BONE PROCEDURES.. 2
1.3 BONE GRAFT SUBSTITUTE MARKET.. 3
1.4 BONE MORPHOGENETIC PROTEIN GROWTH FACTOR MARKET 4
1.5 HYALURONIC ACID VISCOSUPPLEMENTATION MARKET 5
1.6 AUTOLOGOUS CHONDROCYTE IMPLANTATION MARKET .... 6
1.7 COMPETITIVE ANALYSIS .... 7
RESEARCH METHODOLOGY.... 8
2.1 RESEARCH SCOPE 8
2.2 IDATA’S 9-STEP METHODOLOGY . 8
Step 1: Project Initiation & Team Selection 9
Step 2: Prepare Data Systems and Perform Secondary Research 10
Step 3: Preparation for Interviews & Questionnaire Design .. 11
Step 4: Performing Primary Research.. 12
Step 5: Research Analysis: Establishing Baseline Estimates .. 14
Step 6: Market Forecast and Analysis .. 14
Step 7: Identify Strategic Opportunities .... 16
Step 8: Final Review and Market Release . 17
Step 9: Customer Feedback and Market Monitoring 18
EUROPEAN ORTHOPEDIC BIOMATERIALS MARKETS.... 19
3.1 INTRODUCTION .. 19
3.1.1 Products.. 20
3.1.1.1 Growth Factors..20
3.1.1.2 Bone Graft Substitutes .20
3.1.1.3 Hyaluronic Acid Viscosupplementation20
3.1.1.4 Autologous Chondrocyte Implantation.21
3.2 CURRENCY EXCHANGE RATE 21
3.3 MARKET OVERVIEW.... 22
3.4 MARKET BY SEGMENT. 24
3.5 TREND ANALYSIS BY SEGMENT . 29
3.6 MARKET BY COUNTRY 32
3.7 MARKET DRIVERS AND LIMITERS ... 35
3.7.1 Market Drivers.. 35
3.7.2 Market Limiters. 35
3.8 COMPETITIVE ANALYSIS .. 37
3.8.1 Market Concentration. 41
3.9 MERGERS AND ACQUISITIONS .... 42
COUNTRY PROFILES.. 43
4.1 INTRODUCTION .. 43
4.1.1 Population.... 43
4.1.2 GDP per Capita 43
4.1.3 Procedures ... 43
4.1.4 Price Index... 44
4.2 GERMANY 45
4.3 FRANCE.... 46
4.4 UNITED KINGDOM .. 47
4.5 SPAIN .. 48
4.6 ITALY .. 49
4.7 BENELUX . 50
4.8 SCANDINAVIA .... 51
4.9 SWITZERLAND.... 52
4.10 AUSTRIA 53
4.11 PORTUGAL .. 54
4.12 GREECE.. 55
BONE GRAFT SUBSTITUTE MARKET.. 56
5.1 INTRODUCTION .. 56
5.1.1 Volumes Represented per Procedure... 59
5.2 MARKET OVERVIEW.... 60
5.2.1 Total Bone Graft Substitute Procedures by Indication. 60
5.2.2 Total Bone Graft Substitute Procedures by Segment.... 63
5.2.3 Bone Graft Substitute Average Selling Price by Segment.. 67
5.2.4 Bone Graft Substitute Market by Segment 69
5.3 MARKET ANALYSIS AND FORECAST .... 74
5.3.1 Total Bone Graft Substitute Market 74
5.3.2 Total Allograft Market 82
5.3.2.1 Allograft Spine Market 91
5.3.2.2 Allograft Cervical Spine Market.99
5.3.2.3 Allograft Thoracolumbar Spine Market ..107
5.3.2.4 Allograft Trauma and Reconstruction Market...115
5.3.2.5 Allograft Craniomaxillofacial Market 123
5.3.3 Total Synthetic Material Market... 131
5.3.3.1 Synthetic Spine Market ...140
5.3.3.2 Synthetic Cervical Spine Market ...148
5.3.3.3 Synthetic Thoracolumbar Spine Market ..156
5.3.3.4 Synthetic Trauma and Reconstruction Market ..164
5.3.3.5 Synthetic Craniomaxillofacial Market172
5.3.4 Total DBM Market.... 180
5.3.4.1 DBM Spine Market ....188
5.3.4.2 DBM Cervical Spine Market ....196
5.3.4.3 DBM Thoracolumbar Spine Market ...204
5.3.4.4 DBM Trauma and Reconstruction Market ...212
5.3.4.5 DBM Craniomaxillofacial Market.220
5.4 MARKET DRIVERS AND LIMITERS . 228
5.4.1 Market Drivers 228
5.4.2 Market Limiters.... 229
5.5 COMPETITIVE ANALYSIS 232
BONE MORPHOGENETIC PROTEIN GROWTH FACTOR THERAPY
MARKET.. 238
6.1 INTRODUCTION 238
6.2 MARKET ANALYSIS AND FORECAST .. 240
6.3 MARKET DRIVERS AND LIMITERS . 247
6.3.1 Market Drivers 247
6.3.2 Market Limiters.... 247
6.4 COMPETITIVE ANALYSIS 249
HYALURONIC ACID VISCOSUPPLEMENTATION MARKET .... 252
7.1 INTRODUCTION 252
7.2 MARKET OVERVIEW.. 254
7.3 MARKET ANALYSIS AND FORECAST .. 263
7.3.1 Total Hyaluronic Acid Viscosupplementation Market 263
7.3.2 Single-Injection Market . 269
7.3.3 Three-Injection Cycle Market .. 276
7.3.4 Five-Injection Cycle Market .... 283
7.4 MARKET DRIVERS AND LIMITERS . 290
7.4.1 Market Drivers 290
7.4.2 Market Limiters.... 290
7.5 COMPETITIVE ANALYSIS 293
AUTOLOGOUS CHONDROCYTE IMPLANTATION MARKET... 298
8.1 INTRODUCTION 298
8.2 MARKET ANALYSIS AND FORECAST .. 300
8.3 MARKET DRIVERS AND LIMITERS . 307
8.3.1 Market Drivers 307
8.3.2 Market Limiters.... 307
8.4 COMPETITIVE ANALYSIS 309
ABBREVIATIONS... 314
APPENDIX: BONE CEMENT MARKET .... 315
10.1 BONE CEMENT MARKET ANALYSIS AND FORECAST. 315

LIST OF FIGURES

EXECUTIVE SUMMARY.... 1
RESEARCH METHODOLOGY. 8
EUROPEAN ORTHOPEDIC BIOMATERIALS MARKETS .. 19
Figure 3-1: Exchange Rate between Selected European Currencies and the Euro,
2010 21
Figure 3-2: Total European Orthopedic Biomaterials Market, Europe,
2007 – 2017.... 22
Figure 3-3: Total Orthopedic Biomaterials Market, Europe, 2007 – 2017 (€M) .... 25
Figure 3-4: Total Orthopedic Biomaterials Market, Europe, 2007 – 2017 (US$M) 25
Figure 3-5: Orthopedic Biomaterials Market Growth Rates by Segment, Europe,
2007 – 2017.... 30
Figure 3-6: Orthopedic Biomaterials Market by Country, Europe, 2007 – 2017
(€M) 33
Figure 3-7: Orthopedic Biomaterials Market by Country, Europe, 2007 – 2017
(US$M) 34
Figure 3-8: Market Drivers and Limiters, Orthopedic Biomaterials Market,
Europe, 2010 .. 36
Figure 3-9: Leading Competitors, Orthopedic Biomaterials Market, Europe,
2010 39
Figure 3-10: Market Concentration, Orthopedic Biomaterials Market, Europe,
2010 41
COUNTRY PROFILES . 43
Figure 4-1: European Price Index for BGS Materials by Country, 2010 44
BONE GRAFT SUBSTITUTE MARKET 56
Figure 5-1: Total Bone Graft Substitute Procedures by Indication, Europe, 2007
– 2017 .. 60
Figure 5-2: Total Orthopedic Bone Graft Substitute Procedures by Segment,
Europe, 2007 – 2017 . 64
Figure 5-3: Bone Graft Substitute ASP by Segment, Europe, 2007 – 2017 (€) . 67
Figure 5-4: Bone Graft Substitute ASP by Segment, Europe, 2007 – 2017 (US$) . 68
Figure 5-5: Bone Graft Substitute Market by Segment, Europe, 2007 – 2017
(€M) 69
Figure 5-6: Bone Graft Substitute Market by Segment, Europe, 2007 – 2017
(US$M) 70
Figure 5-7: Total Bone Graft Substitute Procedures by Country, Europe,
2007 – 2017.... 75
Figure 5-8: Total Bone Graft Substitute Units Sold by Country, Europe,
2007 – 2017.... 76
Figure 5-9: Total Bone Graft Substitute ASP by Country, Europe, 2007 – 2017
(€) ... 77
Figure 5-10: Total Bone Graft Substitute ASP by Country, Europe, 2007 – 2017
(US$) ... 78
Figure 5-11: Total Bone Graft Substitute Market by Country, Europe, 2007 –
2017 (€M) . 79
Figure 5-12: Total Bone Graft Substitute Market by Country, Europe, 2007 –
2017 (US$M).. 80
Figure 5-13: Total Bone Graft Substitute Market, Europe, 2007 – 2017 (€M) . 81
Figure 5-14: Total Allograft Procedures by Country, Europe, 2007 – 2017 84
Figure 5-15: Total Allograft Units Sold by Country, Europe, 2007 – 2017 . 85
Figure 5-16: Total Allograft ASP by Country, Europe, 2007 – 2017 (€) 86
Figure 5-17: Total Allograft ASP by Country, Europe, 2007 – 2017 (US$) 87
Figure 5-18: Total Allograft Market by Country, Europe, 2007 – 2017 (€M)... 88
Figure 5-19: Total Allograft Market by Country, Europe, 2007-2017 (US$M) 89
Figure 5-20: Allograft Total Spine Procedures by Country, Europe, 2007 – 2017. 92
Figure 5-21: Allograft Total Spine Units Sold by Country, Europe, 2007 – 2017 . 93
Figure 5-22: Allograft Total Spine ASP by Country, Europe, 2007 – 2017 (€) 94
Figure 5-23: Allograft Total Spine ASP by Country, Europe, 2007 – 2017 (US$). 95
Figure 5-24: Allograft Total Spine Market by Country, Europe, 2007 – 2017
(€M) 96
Figure 5-25: Allograft Total Spine Market by Country, Europe, 2007 – 2017
(US$M) 97
Figure 5-26: Allograft Cervical Spine Procedures by Country, Europe,
2007 – 2017.. 100
Figure 5-27: Allograft Cervical Spine Units Sold by Country, Europe,
2007 – 2017.. 101
Figure 5-28: Allograft Cervical Spine ASP by Country, Europe, 2007 – 2017
(€) . 102
Figure 5-29: Allograft Cervical Spine ASP by Country, Europe, 2007 – 2017
(US$) . 103
Figure 5-30: Allograft Cervical Spine Market by Country, Europe, 2007 – 2017
(€M)... 104
Figure 5-31: Allograft Cervical Spine Market by Country, Europe, 2007 – 2017
(US$M) ... 105
Figure 5-32: Allograft Thoracolumbar Spine Procedures by Country, Europe,
2007 – 2017.. 108
Figure 5-33: Allograft Thoracolumbar Spine Units Sold by Country, Europe,
2007 – 2017.. 109
Figure 5-34: Allograft Thoracolumbar Spine ASP by Country, Europe,
2007 – 2017 (€) . 110
Figure 5-35: Allograft Thoracolumbar Spine ASP by Country, Europe,
2007 – 2017 (US$).. 111
Figure 5-36: Allograft Thoracolumbar Spine Market by Country, Europe,
2007 – 2017 (€M) ... 112
Figure 5-37: Allograft Thoracolumbar Spine Market by Country, Europe,
2007 – 2017 (US$M) ... 113
Figure 5-38: Allograft Trauma and Reconstruction Procedures by Country,
Europe, 2007 – 2017 .... 116
Figure 5-39: Allograft Trauma and Reconstruction Units Sold by Country,
Europe, 2007 – 2017 .... 117
Figure 5-40: Allograft Trauma and Reconstruction ASP by Country, Europe,
2007 – 2017 (€) . 118
Figure 5-41: Allograft Trauma and Reconstruction ASP by Country, Europe,
2007 – 2017 (US$).. 119
Figure 5-42: Allograft Trauma and Reconstruction Market by Country, Europe,
2007 – 2017 (€M) ... 120
Figure 5-43: Allograft Trauma and Reconstruction Market by Country, Europe,
2007 – 2017 (US$M) ... 121
Figure 5-44: Allograft Craniomaxillofacial Procedures by Country, Europe,
2007 – 2017.. 124
Figure 5-45: Allograft Craniomaxillofacial Units Sold by Country, Europe,
2007 – 2017.. 125
Figure 5-46: Allograft Craniomaxillofacial ASP by Country, Europe, 2007 – 2017
(€) . 126
Figure 5-47: Allograft Craniomaxillofacial ASP by Country, Europe, 2007 – 2017
(US$) . 127
Figure 5-48: Allograft Craniomaxillofacial Market by Country, Europe,
2007 – 2017 (€M) ... 128
Figure 5-49: Allograft Craniomaxillofacial Market by Country, Europe,
2007 – 2017 (US$M) ... 129
Figure 5-50: Total Synthetic Procedures by Country, Europe, 2007 – 2017 ... 133
Figure 5-51: Total Synthetic Units Sold by Country, Europe, 2007 – 2017.... 134
Figure 5-52: Total Synthetic ASP by Country, Europe, 2007 – 2017 (€) .. 135
Figure 5-53: Total Synthetic ASP by Country, Europe, 2007 – 2017 (US$)... 136
Figure 5-54: Total Synthetic Market by Country, Europe, 2007 – 2017 (€M) 137
Figure 5-55: Total Synthetic Market by Country, Europe, 2007 – 2017 (US$M) 138
Figure 5-56: Synthetic Spine Procedures by Country, Europe, 2007 – 2017 .. 141
Figure 5-57: Synthetic Spine Units Sold by Country, Europe, 2007 – 2017 ... 142
Figure 5-58: Synthetic Spine ASP by Country, Europe, 2007 – 2017 (€) .. 143
Figure 5-59: Synthetic Spine ASP by Country, Europe, 2007 – 2017 (US$) .. 144
Figure 5-60: Synthetic Spine Market by Country, Europe, 2007 – 2017 (€M) 145
Figure 5-61: Synthetic Spine Market by Country, Europe, 2007 – 2017 (US$M) 146
Figure 5-62: Synthetic Cervical Spine Procedures by Country, Europe,
2007 – 2017.. 149
Figure 5-63: Synthetic Cervical Spine Units Sold by Country, Europe,
2007 – 2017.. 150
Figure 5-64: Synthetic Cervical Spine ASP by Country, Europe, 2007 – 2017
(€) . 151
Figure 5-65: Synthetic Cervical Spine ASP by Country, Europe, 2007 – 2017
(US$) . 152
Figure 5-66: Synthetic Cervical Spine Market by Country, Europe, 2007 – 2017
(€M)... 153
Figure 5-67: Synthetic Cervical Spine Market by Country, Europe, 2007 – 2017
(US$M) ... 154
Figure 5-68: Synthetic Thoracolumbar Spine Procedures by Country, Europe,
2007 – 2017.. 157
Figure 5-69: Synthetic Thoracolumbar Spine Units Sold by Country, Europe,
2007 – 2017.. 158
Figure 5-70: Synthetic Thoracolumbar Spine ASP by Country, Europe,
2007 – 2017 (€) . 159
Figure 5-71: Synthetic Thoracolumbar Spine ASP by Country, Europe,
2007 – 2017 (US$).. 160
Figure 5-72: Synthetic Thoracolumbar Spine Market by Country, Europe,
2007 – 2017 (€M) ... 161
Figure 5-73: Synthetic Thoracolumbar Spine Market by Country, Europe,
2007 – 2017 (US$M) ... 162
Figure 5-74: Synthetic Trauma and Reconstruction Procedures by Country,
Europe, 2007 – 2017 .... 165
Figure 5-75: Synthetic Trauma and Reconstruction Units Sold by Country,
Europe, 2007 – 2017 .... 166
Figure 5-76: Synthetic Trauma and Reconstruction ASP by Country, Europe,
2007 – 2017 (€) . 167
Figure 5-77: Synthetic Trauma and Reconstruction ASP by Country, Europe,
2007 – 2017 (US$).. 168
Figure 5-78: Synthetic Trauma and Reconstruction Market by Country, Europe,
2007 – 2017 (€M) ... 169
Figure 5-79: Synthetic Trauma and Reconstruction Market by Country, Europe,
2007 – 2017 (US$M) ... 170
Figure 5-80: Synthetic Craniomaxillofacial Procedures by Country, Europe,
2007 – 2017.. 173
Figure 5-81: Synthetic Craniomaxillofacial Units Sold by Country, Europe,
2007 – 2017.. 174
Figure 5-82: Synthetic Craniomaxillofacial ASP by Country, Europe,
2007 – 2017 (€) . 175
Figure 5-83: Synthetic Craniomaxillofacial ASP by Country, Europe,
2007 – 2017 (US$).. 176
Figure 5-84: Synthetic Craniomaxillofacial Market by Country, Europe,
2007 – 2017 (€M) ... 177
Figure 5-85: Synthetic Craniomaxillofacial Market by Country, Europe,
2007 – 2017 (US$M) ... 178
Figure 5-86: Total DBM Procedures by Country, Europe, 2007 – 2017 .... 181
Figure 5-87: Total DBM Units Sold by Country, Europe, 2007 – 2017 182
Figure 5-88: Total DBM ASP by Country, Europe, 2007 – 2017 (€) ... 183
Figure 5-89: Total DBM ASP by Country, Europe, 2007 – 2017 (US$).... 184
Figure 5-90: Total DBM Market by Country, Europe, 2007 – 2017 (€M) . 185
Figure 5-91: Total DBM Market by Country, Europe, 2007 – 2017 (US$M) . 186
Figure 5-92: DBM Spine Procedures by Country, Europe, 2007 – 2017 ... 189
Figure 5-93: DBM Spine Units Sold by Country, Europe, 2007 – 2017 .... 190
Figure 5-94: DBM Spine ASP by Country, Europe, 2007 – 2017 (€) ... 191
Figure 5-95: DBM Spine ASP by Country, Europe, 2007 – 2017 (US$) ... 192
Figure 5-96: DBM Spine Market by Country, Europe, 2007 – 2017 (€M). 193
Figure 5-97: DBM Spine Market by Country, Europe, 2007 – 2017 (US$M) . 194
Figure 5-98: DBM Cervical Spine Procedures by Country, Europe,
2007 – 2017.. 197
Figure 5-99: DBM Cervical Spine Units Sold by Country, Europe, 2007 – 2017 198
Figure 5-100: DBM Cervical Spine ASP by Country, Europe, 2007 – 2017 (€) .. 199
Figure 5-101: DBM Cervical Spine ASP by Country, Europe, 2007 – 2017
(US$) . 200
Figure 5-102: DBM Cervical Spine Market by Country, Europe, 2007 – 2017
(€M)... 201
Figure 5-103: DBM Cervical Spine Market by Country, Europe, 2007 – 2017
(US$M) ... 202
Figure 5-104: DBM Thoracolumbar Spine Procedures by Country, Europe,
2007 – 2017.. 205
Figure 5-105: DBM Thoracolumbar Spine Units Sold by Country, Europe,
2007 – 2017.. 206
Figure 5-106: DBM Thoracolumbar Spine ASP by Country, Europe, 2007 – 2017
(€) . 207
Figure 5-107: DBM Thoracolumbar Spine ASP by Country, Europe, 2007 – 2017
(US$) . 208
Figure 5-108: DBM Thoracolumbar Spine Market by Country, Europe,
2007 – 2017 (€M) ... 209
Figure 5-109: DBM Thoracolumbar Spine Market by Country, Europe,
2007 – 2017 (US$M) ... 210
Figure 5-110: DBM Trauma and Reconstruction Procedures by Country, Europe,
2007 – 2017.. 213
Figure 5-111: DBM Trauma and Reconstruction Units Sold by Country, Europe,
2007 – 2017.. 214
Figure 5-112: DBM Trauma and Reconstruction ASP by Country, Europe,
2007 – 2017 (€) . 215
Figure 5-113: DBM Trauma and Reconstruction ASP by Country, Europe,
2007 – 2017 (US$).. 216
Figure 5-114: DBM Trauma and Reconstruction Market by Country, Europe,
2007 – 2017 (€M) ... 217
Figure 5-115: DBM Trauma and Reconstruction Market by Country, Europe,
2007 – 2017 (US$M) ... 218
Figure 5-116: DBM Craniomaxillofacial Procedures by Country, Europe,
2007 – 2017.. 221
Figure 5-117: DBM Craniomaxillofacial Units Sold by Country, Europe,
2007 – 2017.. 222
Figure 5-118: DBM Craniomaxillofacial ASP by Country, Europe, 2007 – 2017
(€) . 223
Figure 5-119: DBM Craniomaxillofacial ASP by Country, Europe, 2007 – 2017
(US$) . 224
Figure 5-120: DBM Craniomaxillofacial Market by Country, Europe,
2007 – 2017 (€M) ... 225
Figure 5-121: DBM Craniomaxillofacial Market by Country, Europe,
2007 – 2017 (US$M) ... 226
Figure 5-122: Drivers and Limiters, Bone Graft Substitute Market, Europe, 2007
– 2017 231
Figure 5-123: Leading Competitors, Bone Graft Substitute Market by Country,
Europe, 2010 236
BONE MORPHOGENETIC PROTEIN GROWTH FACTOR THERAPY
MARKET 238
Figure 6-1: Bone Morphogenetic Protein Growth Factor Units (Vials), Europe,
2007 – 2017.. 241
Figure 6-2: Bone Morphogenetic Protein Growth Factor ASP, Europe,
2007 – 2017 (€) . 242
Figure 6-3: Bone Morphogenetic Protein Growth Factor ASP, Europe,
2007 – 2017 (US$).. 243
Figure 6-4: Bone Morphogenetic Protein Growth Factor Therapy Market, Europe,
2007 – 2017 (€M) ... 244
Figure 6-5: Bone Morphogenetic Protein Growth Factor Therapy Market, Europe,
2007 – 2017 (US$M) ... 245
Figure 6-6: Drivers and Limiters, Bone Morphogenetic Growth Factor Therapy
Market, Europe, 2007 – 2017 . 248
Figure 6-7: Leading Competitors, Bone Morphogenetic Growth Factor Therapy
Market, Europe, 2010 .. 250
HYALURONIC ACID VISCOSUPPLEMENTATION MARKET... 252
Figure 7-1: Total Hyaluronic Acid Viscosupplementation Procedures by Segment,
Europe, 2007 – 2017 .... 255
Figure 7-2: Total Hyaluronic Acid Viscosupplementation ASP by Segment,
Europe, 2007 – 2017 (€) ... 256
Figure 7-3: Total Hyaluronic Acid Viscosupplementation ASP by Segment,
Europe, 2007 – 2017 (US$).... 257
Figure 7-4: Total Hyaluronic Acid Viscosupplementation Market by Segment,
Europe, 2007 – 2017 (€M) 258
Figure 7-5: Total Hyaluronic Acid Viscosupplementation Market by Segment,
Europe, 2007 – 2017 (US$M). 259
Figure 7-6: Total Hyaluronic Acid Viscosupplement Injections by Country,
Europe, 2007 – 2017 .... 264
Figure 7-7: Hyaluronic Acid Viscosupplementation ASP by Country, Europe,
2007 – 2017 (€) . 265
Figure 7-8: Hyaluronic Acid Viscosupplementation ASP by Country, Europe,
2007 – 2017 (US$).. 266
Figure 7-9: Total Hyaluronic Acid Viscosupplementation Market by Country,
Europe, 2007 – 2017 (€M) 267
Figure 7-10: Total Hyaluronic Acid Viscosupplementation Market by Country,
Europe, 2007 – 2017 (US$M). 268
Figure 7-11: Single-Injection Procedures by Country, Europe, 2007 – 2017.. 270
Figure 7-12: Single-Injection ASP by Country, Europe, 2007 – 2017 (€) . 271
Figure 7-13: Single-Injection ASP by Country, Europe, 2007 – 2017 (US$).. 272
Figure 7-14: Single-Injection Market by Country, Europe, 2007 – 2017 (€M) .... 273
Figure 7-15: Single-Injection Market by Country, Europe, 2007 – 2017
(US$M) ... 274
Figure 7-16: Three-Injection Cycle Procedures by Country, Europe,
2007 – 2017.. 277
Figure 7-17: Three-Injection Cycle ASP by Country, Europe, 2007 – 2017 (€) .. 278
Figure 7-18: Three-Injection Cycle ASP by Country, Europe, 2007 – 2017
(US$) . 279
Figure 7-19: Three-Injection Cycle Market by Country, Europe, 2007 – 2017
(€M)... 280
Figure 7-20: Three-Injection Cycle Market by Country, Europe, 2007 – 2017
(US$M) ... 281
Figure 7-21: Five-Injection Cycle Procedures by Country, Europe,
2007 – 2017.. 284
Figure 7-22: Five-Injection Cycle ASP by Country, Europe, 2007 – 2017 (€) .... 285
Figure 7-23: Five-Injection Cycle ASP by Country, Europe, 2007 – 2017 (US$) 286
Figure 7-24: Five-Injection Cycle Market by Country, Europe, 2007 – 2017
(€M)... 287
Figure 7-25: Five-Injection Cycle Market by Country, Europe, 2007 – 2017
(US$M) ... 288
Figure 7-26: Drivers and Limiters, Hyaluronic Acid Viscosupplementation
Market, Europe, 2007 – 2017 . 292
Figure 7-27: Leading Competitors, Hyaluronic Acid Viscosupplementation
Market, Europe, 2010 .. 296
AUTOLOGOUS CHONDROCYTE IMPLANTATION MARKET.. 298
Figure 8-1: Autologous Chondrocyte Implantation Market, Europe, 2007 – 2017
(€) . 302
Figure 8-2: Autologous Chondrocyte Implantation Market, Europe, 2007 – 2017
(US$) . 302
Figure 8-3: Autologous Chondrocyte Implantation Units Sold by Country,
Europe, 2007 – 2017 .... 303
Figure 8-4: Autologous Chondrocyte Implantation Market by Country, Europe,
2007 – 2017 (€M) ... 304
Figure 8-5: Autologous Chondrocyte Implantation Market by Country, Europe,
2007 – 2017 (US$M) ... 305
Figure 8-6: Drivers and Limiters, Autologous Chondrocyte Implantation Market,
Europe, 2010 308
Figure 8-7: Leading Competitors, Autologous Chondrocyte Implantation Market,
Europe, 2010 312
ABBREVIATIONS 314
APPENDIX: BONE CEMENT MARKET... 315
Figure 10-1: Premixed Antibiotic Bone Cement Market, Europe, 2007 – 2017
(€) . 316
Figure 10-2: Premixed Antibiotic Bone Cement Market, Europe, 2007 – 2017
(US$) . 316
Figure 10-3: Traditional Bone Cement Market, Europe, 2007-2017 (€) .... 317
Figure 10-4: Traditional Bone Cement Market, Europe, 2007 – 2017 (US$).. 317
Figure 10-5: Leading Competitors, Bone Cement Market, Europe, 2010 .. 318

LIST OF CHARTS

EXECUTIVE SUMMARY.... 1
Chart 1-1: Total Orthopedic Biomaterials Markets, Europe, 2007 – 2017 (€M) . 1
Chart 1-2: Autograft Procedures, Europe, 2017 ... 2
Chart 1-3: Orthopedic Procedures by Bone Graft Substitute, Europe, 2010 .. 3
Chart 1-4: BMP Growth Factor Market, Europe, 2007 – 2017 (€M) ... 4
Chart 1-5: Hyaluronic Acid Viscosupplementation Market by Segment, Europe,
2007 – 2017. 5
Chart 1-6: Autologous Chondrocyte Implantation Market, Europe, 2007 – 2017
(€M).. 6
Chart 1-7: Leading Competitors, Orthopedic Biomaterial Markets, Europe, 2010... 7
RESEARCH METHODOLOGY. 8
EUROPEAN ORTHOPEDIC BIOMATERIALS MARKETS .. 19
Chart 3-1: Total European Orthopedic Biomaterials Market, Europe, 2007 – 2017
(€M) 23
Chart 3-2: Total Orthopedic Biomaterials Market by Segment, Europe,
2007 – 2017 (€M) 26
Chart 3-3: Total Orthopedic Biomaterials Market by Segment, Europe, 2010.. 27
Chart 3-4: Total Orthopedic Biomaterials Market by Segment, Europe, 2017.. 28
Chart 3-5: Total European Orthopedic Biomaterials Market by Segment, Europe,
2008 – 2017.... 31
Chart 3-6: Leading Competitors, Orthopedic Biomaterials Market, Europe, 2010. 40
COUNTRY PROFILES . 43
Chart 4-1: Country Profile, Germany, 2010.. 45
Chart 4-2: Country Profile, France, 2010 46
Chart 4-3: Country Profile, U.K., 2010 ... 47
Chart 4-4: Country Profile, Spain, 2010 .. 48
Chart 4-5: Country Profile, Italy, 2010 ... 49
Chart 4-6: Country Profile, Benelux, 2010 ... 50
Chart 4-7: Country Profile, Scandinavia, 2010 .. 51
Chart 4-8: Country Profile, Switzerland, 2010 .. 52
Chart 4-9: Country Profile, Austria, 2010 .... 53
Chart 4-10: Country Profile, Portugal, 2010 . 54
Chart 4-11: Country Profile, Greece, 2010 ... 55
BONE GRAFT SUBSTITUTE MARKET 56
Chart 5-1: Orthopedic Bone Graft Substitute Procedures by Indication, Europe,
2010 61
Chart 5-2: Orthopedic Bone Graft Substitute Procedures by Indication, Europe,
2017 62
Chart 5-3: Total Orthopedic Bone Graft Substitute Procedures by Segment,
Europe, 2010 .. 65
Chart 5-4: Total Orthopedic Bone Graft Substitute Procedures by Segment,
Europe, 2017 .. 66
Chart 5-5: Bone Graft Substitute Market by Segment, Europe, 2007 – 2017 (€M) 71
Chart 5-6: Bone Graft Substitute Market by Segment, Europe, 2010 72
Chart 5-7: Bone Graft Substitute Market by Segment, Europe, 2017 73
Chart 5-8: Total Allograft Market, Europe, 2007 – 2017 (€M).... 90
Chart 5-9: Allograft Total Spine Market, Europe, 2007 – 2017 (€M) .... 98
Chart 5-10: Allograft Cervical Spine Market, Europe, 2007 – 2017 (€M). 106
Chart 5-11: Allograft Thoracolumbar Spine Market, Europe, 2007 – 2017 (€M) 114
Chart 5-12: Allograft Trauma and Reconstruction Market, Europe, 2007 – 2017
(€M)... 122
Chart 5-13: Allograft Craniomaxillofacial Market, Europe, 2007 – 2017 (€M)... 130
Chart 5-14: Total Synthetic Market, Europe, 2007 – 2017 (€M) 139
Chart 5-15: Synthetic Spine Market, Europe, 2007 – 2017 (€M) .... 147
Chart 5-16: Synthetic Cervical Spine Market, Europe, 2007 – 2017 (€M) 155
Chart 5-17: Synthetic Thoracolumbar Spine Market, Europe, 2007 – 2017 (€M) 163
Chart 5-18: Synthetic Trauma and Reconstruction Spine Market, Europe,
2007 – 2017 (€M) ... 171
Chart 5-19: Synthetic Craniomaxillofacial Spine Market, Europe, 2007 – 2017
(€M)... 179
Chart 5-20: Total DBM Market, Europe, 2007 – 2017 (€M). 187
Chart 5-21: DBM Spine Market, Europe, 2007 – 2017 (€M) 195
Chart 5-22: DBM Cervical Spine Market, Europe, 2007 – 2017 (€M) . 203
Chart 5-23: DBM Thoracolumbar Spine Market, Europe, 2007 – 2017 (€M) . 211
Chart 5-24: DBM Trauma and Reconstruction Spine Market, Europe,
2007 – 2017 (€M) ... 219
Chart 5-25: DBM Craniomaxillofacial Spine Market, Europe, 2007 – 2017
(€M)... 227
Chart 5-26: Leading Competitors, Bone Graft Substitute Market by Country,
Europe, 2010 237
BONE MORPHOGENETIC PROTEIN GROWTH FACTOR THERAPY
MARKET 238
Chart 6-1: Bone Morphogenetic Protein Growth Factor Therapy Market, Europe,
2007 – 2017 (€M) ... 246
Chart 6-2: Leading Competitors, Bone Morphogenetic Growth Factor Therapy
Market, Europe, 2010 .. 251
HYALURONIC ACID VISCOSUPPLEMENTATION MARKET... 252
Chart 7-1: Total Hyaluronic Acid Viscosupplementation Market, Europe,
2007 – 2017 (€M) ... 260
Chart 7-2: Hyaluronic Acid Viscosupplementation Market by Segment, Europe,
2010 ... 261
Chart 7-3: Hyaluronic Acid Viscosupplementation Market by Segment, Europe,
2017 ... 262
Chart 7-4: Total Single-Injection Hyaluronic Acid Viscosupplementation Market,
Europe, 2007 – 2017 (€M) .... 275
Chart 7-5: Three-Injection Cycle Hyaluronic Acid Viscosupplementation Market,
Europe, 2007 – 2017 (€M) 282
Chart 7-6: Five-Injection Cycle Hyaluronic Acid Viscosupplementation Market,
Europe, 2007 – 2017 (€M) 289
Chart 7-7: Leading Competitors, Hyaluronic Acid Viscosupplementation Market,
Europe, 2010 297
AUTOLOGOUS CHONDROCYTE IMPLANTATION MARKET.. 298
Chart 8-1: Autologous Chondrocyte Implantation Market, Europe, 2007 – 2017
(€M)... 306
Chart 8-2: Leading Competitors, Autologous Chondrocyte Implantation Market,
Europe, 2010 313
ABBREVIATIONS 314
APPENDIX: BONE CEMENT MARKET... 315
Chart 10-1: Leading Competitors, Bone Cement Market, Europe, 2010.... 319

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