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Life Science Tools and Reagents: Global Markets

  • May 2016
  • -
  • BCC Research
  • -
  • 277 pages

This BCC Research report explores present and future strategies within the life sciences tools and reagents market, which includes genomics, proteomics, cell biology, antibodies and recombinant protein, animal models, epigenetics, metabolomics, bioinformatics, stem cells, imaging and microscopy. Sales figures are estimated for the five-year period from 2015 through 2020.

Use this report to:

Gain insight into current and future characteristics within the tools and reagents in life sciences and technology.
Analyze global markets for life science tools and reagents by various segments and region.
Identify existing products as well as new developments in the field of life science tools and reagents, issues and factors impacting the global life sciences tools and reagents market.
Assess information about companies and their corporate profile, along with the most relevant patents.

Highlights

The global market for life sciences tools and reagents reached $45.9 billion in 2014 and $48.2 billion in 2015. The market should reach $58.0 billion by 2020, growing at a compound annual growth rate (CAGR) of 3.8% from 2015 to 2020.
The proteomics segment reached $11.3 billion in 2015 and should reach $12.8 billion by 2020, growing at a CAGR of 2.6% from 2015 to 2020.
The global market for Epigenetics tools and reagents reached over $1.5 billion in 2015. The market should reach $2.2 billion by 2020, at a CAGR of 6.9% from 2015 to 2020.

STUDY OBJECTIVES

Life sciences is the study of living organisms and includes many fields of scientific study including molecular biology, genomics, proteomics, cell biology, biochemistry, medicine, computational biology, etc. For these areas of study, a wide variety of tools and techniques are required for continued research and development. The goal of BCC Research in conducting this study is to provide an overview of the current and future characteristics of the global market for life sciences tools and reagents.

This report explores present and future strategies within the life sciences tools and reagents market, which includes such subsciences as genomics, proteomics, cell biology, antibodies and recombinant protein, animal models, epigenetics, metabolomics, bioinformatics, stem cells, imaging and microscopy. The development
of the market, the interruptions and delays and the needs of the market are discussed in this report. The classifications, comparisons and usage of these products are also portrayed in this report.

A detailed analysis of the life sciences tools and reagents products industry structure has been conducted. Revenues are broken down by region. Sales figures are estimated for the five-year period from 2015 through 2020. Markets for life sciences tools and reagents are studied from two perspectives: by region and by type, and each is considered and discussed separately in the report.

REASONS FOR DOING THIS STUDY

Latest advances in life sciences technologies are directed towards high-throughput screening and rapid diagnostics and the like. The life sciences market covers products ranging from advanced instrumentation to laboratory chemicals. Extensive research in the field of life sciences tools and reagents has revealed their usage in developing efficient, user-friendly and affordable scientific technics/products. Modern industries have now begun to take advantage of life sciences tools and reagents products. This has led to the steady market to serve them.

R&D spending, along with increasing competition, patent expiries, advancements, new product launches and new technologies—such as PCR technology, stem cell research and molecular diagnostics, etc.—have led this market in a new direction and have influenced the market to grow for the future. This study looks at a vast array of the
systems affected by these factors.

Acquisition strategies and collaborations by companies are also covered in this report. This study as well discusses the strengths and weaknesses of each type in light of the new technologies, growing competition and changing customer needs.

Table Of Contents

Life Science Tools and Reagents: Global Markets
TABLE OF CONTENTS
CHAPTER 1 INTRODUCTION 2
STUDY OBJECTIVES 2
REASONS FOR DOING THIS STUDY 2
CONTRIBUTIONS OF THE STUDY AND FOR WHOM 3
SCOPE OF THE STUDY 3
METHODOLOGY 3
INFORMATION SOURCES 4
ANALYSTS' CREDENTIALS 4
RELATED BCC RESEARCH REPORTS 4
BCC RESEARCH WEBSITE 5
DISCLAIMER 5
CHAPTER 2 EXECUTIVE SUMMARY 7
SUMMARY TABLE GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY
TYPE, THROUGH 2020 ($ MILLIONS) 8
SUMMARY FIGURE GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY
TYPE, 2013-2020 ($ MILLIONS) 8
CHAPTER 3 OVERVIEW 11
DEFINITION 11
HISTORY OF LIFE SCIENCES 11
TABLE 1 EVOLUTION OF LIFE SCIENCE 11
FIGURE 1 INTEGRATION SCHEME BETWEEN DIFFERENT SCIENTIFIC AREAS OF
RESEARCH 14
GENOMICS 15
TOOLS OF GENOMICS RESEARCH 16
Polymerase Chain Reaction (PCR) 16
Microarray 17
DNA Sequencing 17
RNA Sequencing, or RNA-Seq 17
RNA Interference (RNAi) 17
PROTEOMICS 17
PROTEIN EXPRESSION 19
Vectors 19
Expression Hosts 20
Prokaryotic Expression Systems 20
Eukaryotic Expression Systems 20
Yeast Cell Systems 20
Baculovirus Mediated Insect Cell Expression Systems 21
Mammalian Expression Systems 21
Transgenic Animals 21
Transgenic Plants 21
Cell-Free Systems or In Vitro Expression Systems 22
PROTEIN ISOLATION AND PURIFICATION 22
FIGURE 2 A TYPICAL SCHEME OF PROTEIN EXTRACTION TO CHARACTERIZATION 22
Extraction 23
Isolation/Clarification 23
Purification 23
Electrophoresis 23
Isoelectric Focusing 23
2D-PAGE, or Two-Dimensional Electrophoresis 24
Chromatography 24
PROTEIN IDENTIFICATION AND CHARACTERIZATION 25
X-Ray Crystallography 25
Mass Spectrometry (MS) 26
Nuclear Magnetic Resonance (NMR) 26
Protein Microarray 26
RECOMBINANT PROTEINS 27
CELL BIOLOGY RESEARCH 27
CELL CULTURE MAINTENANCE 27
TRANSFECTION TOOLS AND REAGENTS 28
CELL-BASED ASSAYS 29
G-Protein Coupled Receptors (GPCRs) 29
Ion Channels 30
CELL LINES 30
FLOW CYTOMETRY 31
STEM CELL RESEARCH IN LIFE SCIENCES 32
METABOLOMICS - THE NEW TREND 33
ANTIBODIES - TOOLS AND REAGENTS 34
POLYCLONAL ANTIBODIES 34
MONOCLONAL ANTIBODIES (MABS) 34
RECOMBINANT ANTIBODIES 35
DETECTION PROBES AS REAGENTS FOR LIFE SCENCES 37
FLUORESCENCE 37
CHEMILUMINESCENCE 38
AUTORADIOGRAPHY 38
Enzyme Labels 38
Biotin-Binding Labels 38
Bioluminescent Labels 38
Fluorescent Labels 39
ANIMALS MODELS USED IN LIFE SCIENCES RESEARCH 39
IMAGING TOOLS AND TECHNIQUES 40
LIGHT MICROSCOPY 40
FLUORESCENCE MICROSCOPY 40
CONFOCAL MICROSCOPY 41
ELECTRON MICROSCOPY 41
Transmission Electron Microscope (TEM) 42
Scanning Electron Microscope (SEM) 42
EPIGENETICS TOOLS AND REAGENTS 43
UBIQUITINATION AND DRUG DISCOVERY TOOLS 43
BIOINFORMATICS TOOLS AND SERVICES IN THE LIFE SCIENCES 44
HARDWARE AND SOFTWARE 45
DATABASE SERVICES 45
DATA MANAGEMENT AND STORAGE 45
CHAPTER 4 REGULATORY ASPECTS, NEW DEVELOPMENTS AND PATENTS 48
REGULATORY ASPECTS 48
RECALLS AND SAFETY ALERTS 49
TABLE 2 RECALLS AND SAFETY ALERTS BY COMPANY, 2013-OCTOBER 2015 49
NEW PRODUCTS AND DEVELOPMENT TRENDS 50
KEY ALLIANCES 50
TABLE 3 IMPORTANT MERGERS AND ACQUISITIONS IN THE LIFE SCIENCES TOOLS
AND REAGENTS INDUSTRY, 2013-OCTOBER 2015 50
NEW PRODUCT DEVELOPMENTS 52
TABLE 4 NEW DEVELOPMENTS FOR LIFE SCIENCES TOOLS AND REAGENTS,
2013-OCTOBER 2015 52
AWARDS AND RECOGNITIONS 56
TABLE 5 AWARDS IN FOR LIFE SCIENCES TOOLS AND REAGENTS, 2013-OCTOBER
2015 56
TECHNOLOGY PATENTS IN THE LIFE SCIENCE TOOLS INDUSTRY 58
MAYO COLLABORATIVE SERVICES V. PROMETHEUS LABORATORIES (2012) 58
ASSOCIATION FOR MOLECULAR PATHOLOGY (AMP) V. MYRIAD GENETICS
INC. (2013) 58
ALICE CORP. V. CLS BANK INTERNATIONAL (2014) 59
CHAPTER 5 MARKET ANALYSIS BY TYPE 62
MARKET OVERVIEW 62
MARKET REVENUE 64
TABLE 6 GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY TYPE,
THROUGH 2020 ($ MILLIONS) 65
FIGURE 3 GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY TYPE,
2013-2020 ($ MILLIONS) 65
MARKET SHARE 66
TABLE 7 GLOBAL MARKET SHARE OF LIFE SCIENCES TOOLS AND REAGENTS BY
TYPE, 2014 (%) 66
FIGURE 4 GLOBAL MARKET SHARE OF LIFE SCIENCES TOOLS AND REAGENTS BY
TYPE, 2014 (%) 67
GENOMICS 67
MARKET OVERVIEW 68
MARKET REVENUE 69
TABLE 8 GLOBAL MARKET FOR GENOMICS TOOLS AND REAGENTS BY TYPE,
THROUGH 2020 ($ MILLIONS) 70
FIGURE 5 GLOBAL MARKET FOR GENOMICS TOOLS AND REAGENTS BY TYPE,
2013-2020 ($ MILLIONS) 70
DNA RESEARCH 71
Market Overview 71
Market Revenue 72
TABLE 9 GLOBAL MARKET FOR DNA RESEARCH TOOLS AND REAGENTS BY TYPE,
THROUGH 2020 ($ MILLIONS) 73
FIGURE 6 GLOBAL MARKET FOR DNA RESEARCH TOOLS AND REAGENTS BY TYPE,
2013-2020 ($ MILLIONS) 73
RNA RESEARCH 74
Market Overview 74
Market Revenue 75
TABLE 10 GLOBAL MARKET FOR RNA RESEARCH TOOLS AND REAGENTS BY TYPE,
THROUGH 2020 ($ MILLIONS) 75
FIGURE 7 GLOBAL MARKET FOR RNA RESEARCH TOOLS AND REAGENTS BY TYPE,
2013-2020 ($ MILLIONS) 75
PROTEOMICS 76
MARKET OVERVIEW 77
MARKET REVENUE 78
TABLE 11 GLOBAL MARKET FOR PROTEOMICS TOOLS AND REAGENTS BY TYPE,
THROUGH 2020 ($ MILLIONS) 79
FIGURE 8 GLOBAL MARKET FOR PROTEOMICS TOOLS AND REAGENTS BY TYPE,
2013-2020 ($ MILLIONS) 80
PROTEIN DETECTION 80
Market Overview 81
Market Revenue 82
TABLE 12 GLOBAL MARKET FOR PROTEIN DETECTION RESEARCH TOOLS AND
REAGENTS BY TYPE, THROUGH 2020 ($ MILLIONS) 83
FIGURE 9 GLOBAL MARKET FOR PROTEIN DETECTION RESEARCH TOOLS AND
REAGENTS BY TYPE, 2013-2020 ($ MILLIONS) 83
CELL BIOLOGY, ANTIBODIES AND RECOMBINANT PROTEINS 83
MARKET OVERVIEW 84
MARKET REVENUE 85
TABLE 13 GLOBAL MARKET FOR CELL BIOLOGY, ANTIBODIES AND RECOMBINANT
PROTEIN TOOLS AND REAGENTS BY TYPE, THROUGH 2020 ($ MILLIONS) 85
FIGURE 10 GLOBAL MARKET FOR CELL BIOLOGY, ANTIBODIES AND RECOMBINANT
PROTEIN TOOLS AND REAGENTS BY TYPE, 2013-2020 ($ MILLIONS) 86
CELL BIOLOGY REAGENTS 86
Market Overview 87
Market Revenue 87
TABLE 14 GLOBAL MARKET FOR CELL BIOLOGY TOOLS AND REAGENTS BY TYPE,
THROUGH 2020 ($ MILLIONS) 88
FIGURE 11 GLOBAL MARKET FOR CELL BIOLOGY TOOLS AND REAGENTS BY TYPE,
2013-2020 ($ MILLIONS) 88
ANIMAL MODELS, EPIGENETICS, BIOINFORMATICS, METABOLOMICS, IMAGING
AND MICROSCOPY, AND STEM CELL RESEARCH 89
MARKET OVERVIEW 90
MARKET REVENUE 91
TABLE 15 GLOBAL MARKET FOR ANIMAL MODELS, EPIGENETICS, BIOINFORMATICS,
METABOLOMICS, IMAGING AND MICROSCOPY, AND STEM CELL RESEARCH TOOLS
AND REAGENTS, THROUGH 2020 ($ MILLIONS)
93
FIGURE 12 GLOBAL MARKET FOR ANIMAL MODELS, EPIGENETICS, BIOINFORMATICS,
METABOLOMICS, IMAGING AND MICROSCOPY AND STEM CELL RESEARCH TOOLS
AND REAGENTS, 2013-2020 ($ MILLIONS)
93
CHAPTER 6 MARKET ANALYSIS BY REGION 96
MARKET OVERVIEW 96
MARKET REVENUE 97
TABLE 16 GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 98
FIGURE 13 GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 98
MARKET SHARE 99
TABLE 17 GLOBAL MARKET SHARE OF LIFE SCIENCES TOOLS AND REAGENTS BY
REGION, 2014 (%) 99
FIGURE 14 GLOBAL MARKET SHARE OF LIFE SCIENCES TOOLS AND REAGENTS BY
REGION, 2014 (%) 99
GENOMICS 99
MARKET OVERVIEW 100
MARKET REVENUE 101
TABLE 18 GLOBAL MARKET FOR GENOMICS TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 101
FIGURE 15 GLOBAL MARKET FOR GENOMICS TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 101
DNA RESEARCH TOOLS AND REAGENTS 102
Market Overview 102
Market Revenue 103
TABLE 19 GLOBAL MARKET FOR DNA RESEARCH TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 104
FIGURE 16 GLOBAL MARKET FOR DNA RESEARCH TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 104
Polymerase Chain Reaction 104
Market Overview 105
Market Revenue 106
TABLE 20 GLOBAL MARKET FOR POLYMERASE CHAIN REACTION TOOLS AND
REAGENTS BY REGION, THROUGH 2020 ($ MILLIONS) 107
FIGURE 17 GLOBAL MARKET FOR POLYMERASE CHAIN REACTION TOOLS AND
REAGENTS BY REGION, 2013-2020 ($ MILLIONS) 107
Sequencing and Next-Generation Sequencing 107
Market Overview 108
Market Revenue 109
TABLE 21 GLOBAL MARKET FOR SEQUENCING AND NEXT-GENERATION
SEQUENCING TOOLS AND REAGENTS BY REGION, THROUGH 2020 ($ MILLIONS) 110
FIGURE 18 GLOBAL MARKET FOR SEQUENCING AND NEXT-GENERATION
SEQUENCING TOOLS AND REAGENTS BY REGION, 2013-2020 ($ MILLIONS) 110
Microarrays 111
Market Overview 111
Market Revenue 113
TABLE 22 GLOBAL MARKET FOR MICROARRAY TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 113
FIGURE 19 GLOBAL MARKET FOR MICROARRAY TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 113
Other Tools and Reagents Used in DNA Research 114
Market Overview 115
Market Revenue 115
TABLE 23 GLOBAL MARKET FOR OTHER TOOLS AND REAGENTS USED IN DNA
RESEARCH BY REGION, THROUGH 2020 ($ MILLIONS) 115
FIGURE 20 GLOBAL MARKET FOR OTHER TOOLS AND REAGENTS USED IN DNA
RESEARCH BY REGION, 2013-2020 ($ MILLIONS) 116
RNA RESEARCH 116
Market Overview 117
Market Revenue 117
TABLE 24 GLOBAL MARKET FOR RNA RESEARCH TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 118
FIGURE 21 GLOBAL MARKET FOR RNA RESEARCH TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 118
RNA Interference (RNAi) 118
Market Overview 119
Market Revenue 119
TABLE 25 GLOBAL MARKET FOR RNA INTERFERENCE TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 120
FIGURE 22 GLOBAL MARKET FOR RNA INTERFERENCE TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 120
Other Tools and Reagents Used in RNA Research 121
Market Overview 121
Market Revenue 122
TABLE 26 GLOBAL MARKET FOR OTHER TOOLS AND REAGENTS USED IN RNA
RESEARCH BY REGION, THROUGH 2020 ($ MILLIONS) 122
FIGURE 23 GLOBAL MARKET FOR OTHER TOOLS AND REAGENTS USED IN RNA
RESEARCH BY REGION, 2013-2020 ($ MILLIONS) 123
PROTEOMICS 123
MARKET OVERVIEW 125
MARKET REVENUE 125
TABLE 27 GLOBAL MARKET FOR PROTEOMICS TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 126
FIGURE 24 GLOBAL MARKET FOR PROTEOMICS TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 126
PROTEIN EXPRESSION 127
Market Overview 127
Market Revenue 128
TABLE 28 GLOBAL MARKET FOR PROTEIN EXPRESSION TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 129
FIGURE 25 GLOBAL MARKET FOR PROTEIN EXPRESSION TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 129
PROTEIN PURIFICATION BY CHROMATOGRAPHY 129
Market Overview 130
Market Revenue 131
TABLE 29 GLOBAL MARKET FOR PROTEIN CHROMATOGRAPHY TOOLS AND
REAGENTS BY REGION, THROUGH 2020 ($ MILLIONS) 131
FIGURE 26 GLOBAL MARKET FOR PROTEIN CHROMATOGRAPHY TOOLS AND
REAGENTS BY REGION, 2013-2020 ($ MILLIONS) 131
PROTEIN DETECTION 132
Market Overview 132
Market Revenue 133
TABLE 30 GLOBAL MARKET FOR PROTEIN DETECTION TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 133
FIGURE 27 GLOBAL MARKET FOR PROTEIN DETECTION TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 134
Mass Spectrometry (MS) 134
Market Overview 135
Market Revenue 135
TABLE 31 GLOBAL MARKET FOR MASS SPECTROMETRY TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 136
FIGURE 28 GLOBAL MARKET FOR MASS SPECTROMETRY TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 136
Nuclear Magnetic Resonance (NMR) 136
Market Overview 137
Market Revenue 138
TABLE 32 GLOBAL MARKET FOR NMR TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 138
FIGURE 29 GLOBAL MARKET FOR NMR TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 138
Two-Dimensional Polyacrylamide Gel Electrophoresis (2D-PAGE) 139
Market Overview 139
Market Revenue 140
TABLE 33 GLOBAL MARKET FOR 2D-PAGE TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 140
FIGURE 30 GLOBAL MARKET FOR 2D-PAGE TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 140
Protein Chip 141
Market Overview 142
Market Revenue 142
TABLE 34 GLOBAL MARKET FOR PROTEIN CHIP TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 143
FIGURE 31 GLOBAL MARKET FOR PROTEIN CHIP TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 143
CELL BIOLOGY, ANTIBODIES AND RECOMBINANT PROTEIN 143
MARKET OVERVIEW 144
MARKET REVENUE 144
TABLE 35 GLOBAL MARKET FOR CELL BIOLOGY, ANTIBODIES AND RECOMBINANT
PROTEIN TOOLS AND REAGENTS BY REGION, THROUGH 2020 ($ MILLIONS) 145
FIGURE 32 GLOBAL MARKET FOR CELL BIOLOGY, ANTIBODIES AND RECOMBINANT
PROTEIN TOOLS AND REAGENTS BY REGION, 2013-2020 ($ MILLIONS) 145
RECOMBINANT PROTEINS 146
Market Overview 147
Market Revenue 147
TABLE 36 GLOBAL MARKET FOR RECOMBINANT PROTEIN TOOLS AND REAGENTS
BY REGION, THROUGH 2020 ($ MILLIONS) 148
FIGURE 33 GLOBAL MARKET FOR RECOMBINANT PROTEIN TOOLS AND REAGENTS
BY REGION, 2013-2020 ($ MILLIONS) 148
ANTIBODIES 148
Market Overview 149
Market Revenue 149
TABLE 37 GLOBAL MARKET FOR ANTIBODIES TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 150
FIGURE 34 GLOBAL MARKET FOR ANTIBODIES TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 150
CELL BIOLOGY REAGENTS 151
Market Overview 151
Market Revenue 151
TABLE 38 GLOBAL MARKET FOR CELL BIOLOGY TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 152
FIGURE 35 GLOBAL MARKET FOR CELL BIOLOGY TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 152
Flow Cytometry 153
Market Overview 153
Market Revenue 154
TABLE 39 GLOBAL MARKET FOR FLOW CYTOMETRY TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 154
FIGURE 36 GLOBAL MARKET FOR FLOW CYTOMTERY TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 155
Cell-Based Assays 155
Market Overview 156
Market Revenue 156
TABLE 40 GLOBAL MARKET FOR CELL-BASED ASSAY TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 157
FIGURE 37 GLOBAL MARKET FOR CELL-BASED ASSAY TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 157
ANIMAL MODELS 158
Market Overview 158
Market Revenue 158
TABLE 41 GLOBAL MARKET FOR ANIMAL MODELS BY REGION, THROUGH 2020 ($
MILLIONS) 159
FIGURE 38 GLOBAL MARKET FOR ANIMAL MODELS BY REGION, 2013-2020 ($
MILLIONS) 159
EPIGENETICS 160
Market Overview 161
Market Revenue 161
TABLE 42 GLOBAL MARKET FOR EPIGENETICS TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 162
FIGURE 39 GLOBAL MARKET FOR EPIGENETICS TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 162
METABOLOMICS 163
Market Overview 163
Market Revenue 164
TABLE 43 GLOBAL MARKET FOR METABOLOMICS TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 164
FIGURE 40 GLOBAL MARKET FOR METABOLOMICS TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 164
BIOINFORMATICS 165
Market Overview 165
Market Revenue 166
TABLE 44 GLOBAL MARKET FOR BIOINFORMATICS TOOLS AND REAGENTS BY
REGION, THROUGH 2020 ($ MILLIONS) 167
FIGURE 41 GLOBAL MARKET FOR BIOINFORMATICS TOOLS AND REAGENTS BY
REGION, 2013-2020 ($ MILLIONS) 167
IMAGING AND MICROSCOPY 168
Market Overview 168
Market Revenue 169
TABLE 45 GLOBAL MARKET FOR IMAGING AND MICROSCOPY TOOLS AND
REAGENTS BY REGION, THROUGH 2020 ($ MILLIONS) 169
FIGURE 42 GLOBAL MARKET FOR IMAGING AND MICROSCOPY TOOLS AND
REAGENTS BY REGION, 2013-2020 ($ MILLIONS) 170
STEM CELLS 170
Market Overview 171
Market Revenue 172
TABLE 46 GLOBAL MARKET FOR STEM CELLS TOOLS AND REAGENTS BY REGION,
THROUGH 2020 ($ MILLIONS) 172
FIGURE 43 GLOBAL MARKET FOR STEM CELLS TOOLS AND REAGENTS BY REGION,
2013-2020 ($ MILLIONS) 172
CHAPTER 7 INDUSTRY STRUCTURE 175
GENOMICS 175
POLYMERASE CHAIN REACTION 175
Market Leaders 175
TABLE 47 LEADING MANUFACTURERS/SUPPLIERS OF POLYMERASE CHAIN
REACTION TOOLS AND REAGENTS, 2014 175
Market Shares 177
TABLE 48 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS FOR
POLYMERASE CHAIN REACTION TOOLS AND REAGENTS, 2014 (%) 177
FIGURE 44 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS FOR
POLYMERASE CHAIN REACTION TOOLS AND REAGENTS, 2014 (%) 177
SEQUENCING AND NEXT-GENERATION SEQUENCING 178
Market Leaders 178
TABLE 49 LEADING MANUFACTURERS/ SUPPLIERS OF SEQUENCING AND
NEXT-GENERATION SEQUENCING TOOLS AND REAGENTS, 2014 178
Market Shares 180
TABLE 50 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
SEQUENCING AND NEXT-GENERATION SEQUENCING TOOLS AND REAGENTS, 2014
(%)
180
FIGURE 45 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF TOOLS
AND REAGENTS FOR SEQUENCING AND NEXT-GENERATION SEQUENCING, 2014 (%) 180
MICROARRAYS 181
Market Leaders 181
TABLE 51 LEADING MANUFACTURERS/ SUPPLIERS OF MICROARRAY TOOLS AND
REAGENTS, 2014 181
Market Shares 182
TABLE 52 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
MICROARRAY TOOLS AND REAGENTS, 2014 (%) 183
FIGURE 46 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
MICROARRAY TOOLS AND REAGENTS, 2014 (%) 183
OTHER DNA RESEARCH TOOLS AND REAGENTS 184
Market Leaders 184
TABLE 53 LEADING MANUFACTURERS/ SUPPLIERS OF OTHER DNA RESEARCH
TOOLS AND REAGENTS, 2014 184
Market Shares 185
TABLE 54 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF OTHER
DNA RESEARCH TOOLS AND REAGENTS , 2014 (%) 185
FIGURE 47 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF OTHER
DNA RESEARCH TOOLS AND REAGENTS, 2014 (%) 186
RNA INTERFERENCE 186
Market Leaders 186
TABLE 55 LEADING MANUFACTURERS/ SUPPLIERS OF OTHER RNA INTERFERENCE
TOOLS AND REAGENTS, 2014 187
Market Shares 188
TABLE 56 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF RNA
INTERFERENCE TOOLS AND REAGENTS, 2014 (%) 188
FIGURE 48 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF RNA
INTERFERENCE TOOLS AND REAGENTS, 2014 (%) 188
OTHER RNA RESEARCH TOOLS AND REAGENTS 189
Market Leaders 189
TABLE 57 LEADING MANUFACTURERS/ SUPPLIERS OF OTHER RNA RESEARCH
TOOLS AND REAGENTS, 2014 189
Market Shares 191
TABLE 58 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF OTHER
RNA RESEARCH TOOLS AND REAGENTS, 2014 (%) 191
FIGURE 49 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF OTHER
RNA RESEARCH TOOLS AND REAGENTS, 2014 (%) 191
PROTEOMICS 192
PROTEIN EXPRESSION 192
Market Leaders 192
TABLE 59 LEADING MANUFACTURERS/ SUPPLIERS OF PROTEIN EXPRESSION TOOLS
AND REAGENTS, 2014 192
Market Shares 193
TABLE 60 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF PROTEIN
EXPRESSION TOOLS AND REAGENTS, 2014 (%) 194
FIGURE 50 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
PROTEIN EXPRESSION TOOLS AND REAGENTS, 2014 (%) 194
CHROMATOGRAPHY 195
Market Leaders 195
TABLE 61 LEADING MANUFACTURERS/ SUPPLIERS OF CHROMATOGRAPHY TOOLS
AND REAGENTS, 2014 195
Market Shares 197
TABLE 62 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
CHROMATOGRAPHY TOOLS AND REAGENTS, 2014 (%) 197
FIGURE 51 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
CHROMATOGRAPHY TOOLS AND REAGENTS, 2014 (%) 197
MASS SPECTROMETRY 198
Market Leaders 198
TABLE 63 LEADING MANUFACTURERS/ SUPPLIERS OF MASS SPECTROMETRY
TOOLS AND REAGENTS, 2014 198
Market Shares 199
TABLE 64 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF MASS
SPECTROMETRY TOOLS AND REAGENTS, 2014 (%) 200
FIGURE 52 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF MASS
SPECTROMETRY TOOLS AND REAGENTS, 2014 (%) 200
NUCLEAR MAGNETIC RESONANCE (NMR) 201
Market Leaders 201
TABLE 65 LEADING MANUFACTURERS/ SUPPLIERS OF NMR TOOLS AND REAGENTS,
2014 201
Market Shares 201
TABLE 66 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF NMR
TOOLS AND REAGENTS, 2014 (%) 202
FIGURE 53 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF NMR
TOOLS AND REAGENTS, 2014 (%) 202
TWO-DIMENSIONAL POLYACRYLAMIDE GEL ELECTRPHORESIS (2D-PAGE) 202
Market Leaders 202
TABLE 67 LEADING MANUFACTURERS/ SUPPLIERS OF 2D-PAGE TOOLS AND
REAGENTS, 2014 202
Market Shares 203
TABLE 68 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF 2D-PAGE
TOOLS AND REAGENTS, 2014 (%) 204
FIGURE 54 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF 2D
PAGE TOOLS AND REAGENTS, 2014 (%) 204
PROTEIN CHIP 204
Market Leaders 204
TABLE 69 LEADING MANUFACTURERS/ SUPPLIERS OF PROTEIN CHIP TOOLS AND
REAGENTS, 2014 205
Market Shares 205
TABLE 70 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF PROTEIN
CHIP TOOLS AND REAGENTS, 2014 (%) 205
FIGURE 55 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
PROTEIN CHIP TOOLS AND REAGENTS, 2014 (%) 206
ANTIBODIES, CELL BIOLOGY AND RECOMBINANT PROTEINS 206
RECOMBINANT PROTEINS 206
Market Leaders 207
TABLE 71 LEADING MANUFACTURERS/ SUPPLIERS OF RECOMBINANT PROTEIN
TOOLS AND REAGENTS, 2014 207
Market Shares 207
TABLE 72 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
RECOMBINANT PROTEIN TOOLS AND REAGENTS, 2014 (%) 208
FIGURE 56 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
RECOMBINANT PROTEIN TOOLS AND REAGENTS, 2014 (%) 208
ANTIBODIES 209
Market Leaders 209
TABLE 73 LEADING MANUFACTURERS/ SUPPLIERS OF ANTIBODIES TOOLS AND
REAGENTS, 2014 209
Market Shares 210
TABLE 74 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
ANTIBODIES TOOLS AND REAGENTS, 2014 (%) 211
FIGURE 57 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
ANTIBODIES TOOLS AND REAGENTS, 2014 (%) 211
CELL BASED ASSAYS 212
Market Leaders 212
TABLE 75 LEADING MANUFACTURERS/ SUPPLIERS OF CELL-BASED ASSAY TOOLS
AND REAGENTS, 2014 212
Market Shares 213
TABLE 76 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
CELL-BASED ASSAY TOOLS AND REAGENTS, 2014 (%) 214
FIGURE 58 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
CELL-BASED ASSAY TOOLS AND REAGENTS, 2014 (%) 214
FLOW CYTOMETRY 215
Market Leaders 215
TABLE 77 LEADING MANUFACTURERS/ SUPPLIERS OF FLOW CYTOMETRY TOOLS
AND REAGENTS, 2014 215
Market Shares 216
TABLE 78 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF FLOW
CYTOMETRY TOOLS AND REAGENTS, 2014 (%) 216
FIGURE 59 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF FLOW
CYTOMETRY TOOLS AND REAGENTS, 2014 (%) 216
ANIMAL MODELS, EPIGENETICS, METABOLOMICS, BIOINFORMATICS, IMAGING
ANG MICROSCOPY AND STEM CELLS 217
ANIMAL MODELS 217
Market Leaders 217
TABLE 79 LEADING MANUFACTURERS/ SUPPLIERS OF ANIMAL MODELS, 2014 218
Market Shares 218
TABLE 80 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF ANIMAL
MODELS, 2014 (%) 219
FIGURE 60 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF ANIMAL
MODELS, 2014 (%) 219
EPIGENETIC TOOLS AND REAGENTS 219
Market Leaders 219
TABLE 81 LEADING MANUFACTURERS/ SUPPLIERS OF EPIGENETIC TOOLS AND
REAGENTS, 2014 219
Market Shares 221
TABLE 82 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS FOR
EPIGENETIC TOOLS AND REAGENTS, 2014 (%) 221
FIGURE 61 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS FOR
EPIGENETIC TOOLS AND REAGENTS, 2014 (%) 221
METABOLOMICS TOOLS AND REAGENTS 222
Market Leaders 222
TABLE 83 LEADING MANUFACTURERS/ SUPPLIERS OF METABOLOMIC TOOLS AND
REAGENTS, 2014 222
Market Shares 223
TABLE 84 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
METABOLOMICS TOOLS AND REAGENTS, 2014 (%) 223
FIGURE 62 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
METABOLOMICS TOOLS AND REAGENTS, 2014 (%) 223
BIOINFORMATICS TOOLS AND REAGENTS 224
Market Leaders 224
TABLE 85 LEADING MANUFACTURERS/ SUPPLIERS OF BIOINFORMATICS TOOLS AND
REAGENTS, 2014 224
Market Shares 226
TABLE 86 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
BIOINFORMATICS TOOLS AND REAGENTS, 2014 (%) 226
FIGURE 63 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
BIOINFORMATICS TOOLS AND REAGENTS, 2014 (%) 226
IMAGING AND MICROSCOPY TOOLS AND REAGENTS 227
Market Leaders 227
TABLE 87 LEADING MANUFACTURERS/ SUPPLIERS OF IMAGING AND MICROSCOPY
TOOLS AND REAGENTS, 2014 227
Market Shares 228
TABLE 88 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF IMAGING
AND MICROSCOPY TOOLS AND REAGENTS, 2014 (%) 229
FIGURE 64 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF
IMAGING AND MICROSCOPY TOOLS AND REAGENTS, 2014 (%) 229
STEM CELL TOOLS AND REAGENTS 230
Market Leaders 230
TABLE 89 LEADING MANUFACTURERS/ SUPPLIERS OF STEM CELL TOOLS AND
REAGENTS, 2014 230
Market Shares 231
TABLE 90 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF STEM
CELL TOOLS AND REAGENTS, 2014 (%) 231
FIGURE 65 GLOBAL MARKET SHARES OF MANUFACTURERS/ SUPPLIERS OF STEM
CELL TOOLD AND REAGENTS, 2014 (%) 231
CHAPTER 8 CURRENT SITUATION 233
DRIVERS FOR THE LIFE SCIENCE TOOLS AND REAGENTS INDUSTRY 233
DEMOGRAPHIC DRIVERS 233
PERSONALIZED MEDICINE 234
TECHNOLOGY INNOVATION 234
MERGERS AND ACQUISITIONS (MandA) 234
RandD PRODUCTIVITY 234
A CHANGING REGULATORY ENVIRONMENT 235
PRICING 236
CHALLENGES FOR THE LIFE SCIENCE TOOLS AND REAGENT INDUSTRY 236
MAINTAINING REGULATORY COMPLIANCE 236
COLLABORATIONS 236
A SHRINKING WORLD 237
CYBERSECURITY 237
REPRODUCIBILITY FOR ANTIBODY REAGENTS 237
HEALTH CARE REFORM (ACA) 237
OPPORTUNITIES IN THE LIFE SCIENCES TOOLS AND REAGENTS INDUSTRY 237
THE NEED FOR INNOVATION 238
EMERGING MARKETS 238
COLLABORATIVE RESEARCH AND DEVELOPMENT 239
DIGITAL TECHNOLOGIES 239
CHAPTER 9 COMPANY PROFILES 241
ABBOTT LABORATORIES 241
ABCAM 241
ABGENT INC. 241
AB SCIEX 242
ACTIVE MOTIF 242
AFFYMETRIX 243
AGENA BIOSCIENCE 243
AGILENT TECHNOLOGIES 244
ALDEVRON 244
ALLELE BIOTECHNOLOGY 245
ALPHAHELIX MOLECULAR DIAGNOSTICS AB 245
AMPLICON EXPRESS 246
ANASPEC (EUROGENTEC GROUP) 246
APPLIED SPECTRAL IMAGING INC. 246
ATACTIC TECHNOLOGIES 247
AVIVA BIOSCIENCES CORP. 247
BD BIOSCIENCES 248
BECKMAN COULTER INC. 249
BENITEC 249
BIO-RAD LABORATORIES 249
BIOLIFE SOLUTIONS INC. 250
BIOLOG 250
BIOMYX TECHNOLOGY 251
BIONEER 251
BIO-TECHNE 252
BIOVISION 252
BRUKER CORP. 253
BTX INSTRUMENT DIVISION 254
CELL SCIENCES 254
CELL SIGNALING TECHNOLOGY 254
CEPHEID INC. 255
CHARLES RIVER LABORATORIES INTERNATIONAL INC. 255
CHEMGENES CORP. 256
CISBIO BIOASSAYS 257
COMPLETE GENOMICS INC. 257
COVANCE INC. 258
CYTORI THERAPEUTICS INC. 258
DANAHER CORP. 259
DNA2.0 259
DYOMICS GMBH 260
ECHELON BIOSCIENCES INC. 260
EMD MILLIPORE 261
ENZO BIOCHEM 261
EPPENDORF AG 262
F. HOFFMANN-LA ROCHE AG (ROCHE) 262
GE HEALTHCARE LIFE SCIENCES 263
GENETEX INC. 263
GENOME EXPLORATIONS 263
GILSON INC. 264
GENOWAY 264
HIGH THROUGHPUT GENOMICS INC. 265
ILLUMINA INC. 265
INTEGRATED DNA TECHNOLOGIES INC. 266
IRVINE SCIENTIFIC 266
ISIS (IONIS) PHARMACEUTICALS 267
JEOL LTD. 267
LEICA MICROSYSTEMS INC. 268
LI-COR 268
LIFESENSORS INC. 269
LONZA GROUP AG 269
LUMINEX CORP. 270
NEW ENGLAND BIOLABS 270
NOVOZYMES 271
OLYMPUS CORP. 271
ORIGENE TECHNOLOGIES 272
PERKIN-ELMER 272
PROMEGA CORP. 273
PROSCI INC. 274
PROTEA BIOSCIENCES INC. 274
PROTEIN SIMPLE 275
SHIMADZU CORP. 275
SIEMENS HEALTHCARE GMBH 276
SIGMA-ALDRICH 276
STEMCELL TECHNOLOGIES INC. 277
STEMGENT 277
SYSMEX-PARTEC GMBH 278
THERMO FISHER SCIENTIFIC INC. 278
TRILINK BIOTECHNOLOGIES 279
TOCRIS BIOSCIENCE (BIO-TECHNE) 279
VITRO DIAGNOSTICS INC. 280
WATERS CORP. 280
XENOTECH LLC 281
CHAPTER 10 ABBREVIATIONS 283

LIST OF TABLES

SUMMARY TABLE GLOBAL MARKET FOR LIFE SCIENCES TOOLS AND REAGENTS BY
TYPE, THROUGH 2020 ($ MILLIONS) 8
TABLE 1 EVOLUTION OF LIFE SCIENCE 11
TABLE 2 RECALLS AND SAFETY ALERTS BY COMPANY, 2013-OCTOBER 2015 49
TABLE 3 IMPORTANT MERGERS AND ACQUISITIONS IN THE LIFE SCIENCES TOOLS
AND REAGENTS INDUSTRY, 2013-OCTOBER 2015 50
TABLE 4 NEW DEVELOPMENTS FOR LIFE SCIENCES TOOLS AND REAGENTS,
2013-OCTOBER 2015 52

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