Orthopedic Biomaterials, The World Market

  • May 2011
  • -
  • Kalorama Information

Orthopedic biomaterial products, which can be organic or synthetic in nature, are implanted into or near a bone fracture to facilitate healing or to compensate for a lack or loss of bone tissue. Biomaterials are expected to be biocompatible and not cause inflammation or rejection. Biomaterials used in orthopedic surgery include autografts, allografts, xenografts, ceramics, polymers, bone growth factors and synovial fluid substitutes. Among the prominent applications for orthopedic biomaterials are surface coatings for hip prostheses, bone cements, bone defect fillers, and fracture fixation plates.


This report focuses on orthopedic biomaterials. The specific areas covered in this report are the products and markets for bone allografts and bone graft substitutes, which include allograft bone substitutes, ceramic-based, polymer-based, factor-based (recombinant growth factors) and hyaluronic acid synovial Fluid substitutes.


Kalorama's Orthopedic Biomaterials, World Market, one of the few resources available on this market, looks at the Market for biomaterials, including the following segments:


  • Allograft Products (including DBM, Machined Bone and Standard Allograft)

  • Ceramic Products

  • Polymer Products

  • rhBMP Products

  • HA Viscosupplemental Products

Table Of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

Overview

Scope and Methodology

Musculoskeletal Conditions/Treatments

Prevalence of Musculoskeletal Conditions

Most Common Musculoskeletal Conditions

Joint Replacement Procedures

Gene Therapy and Tissue Engineering

Genetically Engineered Stem Cells

Biomaterials Products

Global Orthopedic Biomaterials Market

Market Segment Analysis

Allograft Bone Substitutes

Ceramic-based Bone Substitutes

Polymer-based Bone Substitutes

BMP Products

HA Viscosupplementation Substitutes

CHAPTER TWO: INTRODUCTION

Bone Characteristics

Types of Bone

Cortical Bone

Cancellous Bone

Bone Cells

Osteoblasts

Osteoclasts

Osteocytes

The Functions of Bone

Bone Matrix

Joint Components

Prevalence of Musculoskeletal conditions

Musculoskeletal Conditions In Europe

Musculoskeletal Conditions In the United States

Common Musculoskeletal Conditions

Arthritis

Osteoarthritis

Bone Fractures

Ligament Injuries

Joint Replacement Procedures

Introduction

Knee Reconstruction

Hip Reconstruction

Spine Fusion

Artificial Disc Replacement

Gene Therapy and Tissue Engineering

Genetically Engineered Stem Cells

CHAPTER THREE: TYPES OF MATERIALS

Overview

Brief History of Orthopedic Biomaterials

Categories of Orthopedic Biomaterials

Bone Grafts

Overview

Types of Bone Grafts

Autografts

Advantages

Disadvantages

Allograft

Xenografts

Advantages

Disadvantages

Allograft Bone Graft Substitutes

Overview

Demineralized Bone Matrix

Types of DBM Products

Stem Cell-based Allograft

Conventional Allograft

Machined Allograft

Ceramic-based Bone Graft Substitutes

Overview

Types of Materials

Hydroxyapatite

Ceramic Coated Joint Implants

Coralline Hydroxyapatite

Tricalcium phosphate

Calcium Phosphate

Calcium Sulphate

Polymer-based Bone Graft Substitutes

Overview

Nondegradable Polymers

Bioabsorbable Polymer Biomaterials

Polylactic Acid (PLA)

Polyglycolic Acid (PGA)

Copolymers

Factor- based Bone Graft Substitutes

Overview

Types of Growth Factors

Bone Morphogenic Protein (BMP)

Transforming Growth Factor-Beta (TGF-?)

Fibroblast Growth Factors (FGFs)

Insulin-Like Growth Factors (IGFs)

Platelet-Derived Growth Factor (PDGF)

Carriers/Delivery Systems for Growth Factors

Type-1 Collagen

Demineralized Bone Matrix (DBM)

Polymers

Ceramics

Hyaluronic Acid

Gene Therapy

Hyaluronic Acid Synovial Fluid Substitute

Overview

Viscosupplementation

CHAPTER FOUR: ORTHOPEDIC BIOMATERIALS MARKETS

Introduction

Global Market Analysis and Forecast

Orthopedic Biomaterial Market Drivers

Orthopedic Biomaterials Market Forecast

Global Regional Markets

Market Segment Analysis

Market Value and Growth by Segment

Allograft Bone Market Analysis

Allograft Applications

Spinal Fusion

Trauma

Joint Revision

Allograft Products

DBM

Machined Bone Products

Allograft Stem Cell Products

Trinity Evolution

Osteocel

PureGen

AlloStem

BioDfactor

Allograft Bone Market

Market Drivers and Limitations

Allograft Bone Competitors’ Market Share

Ceramic-based Bone Substitute Market Analysis

Ceramic Applications and Products

Ceramic-based Implants

Ceramic-based Bone Substitute Products

Ceramic Biomaterials Market

Market Drivers and Limitations

Ceramic Competitors’ Market Share

Polymer-based Bone Substitutes Market Analysis

PEEK Applications

Bioabsorbable Polymers

Applications for Polymer Bioabsorbable Biomaterials

Combination Products

Polymer-based Biomaterials Market

Market Drivers

Competitors’ Market Share

Bone Morphogenetic Proteins Market Analysis

Products and Applications

InFuse and InductOS (RhBMP-2)

OP-1 (rhBMP-7)

Carrier Materials for BMPs

BMP World Market

Current Market Status

HA Viscosupplementation Market Analysis

Market Drivers and Trends

HA Viscosupplementation Competitors’ Market Share

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