Pharmaceutical Packaging

Pharmaceutical Packaging

This comprehensive study analyzes the US market (including Puerto Rico) for pharmaceutical packaging products and materials. Products covered include primary containers (blister packaging, plastic bottles, pouches and strip packaging, prefillable inhalers, prefillable syringes, medication tubes, parenteral vials and ampuls, IV containers, and other containers, such as aerosol containers, glass bottles and jars, and paperboard boxes), secondary containers (folding paperboard boxes, prescription containers, shipping containers, thermoformed kits and trays, and other containers, such as clamshell packs and header bags), and packaging accessories (caps and closures, package inserts, labels, shrink wrap, inner seals and other items). Basic compounds and semi-finished components based on plastics, paper and paperboard, foil and glass comprise the principal materials examined. The study also features a discussion of key pharmaceutical packaging end-use markets (pharmaceutical manufacturing, contract packaging, retail pharmacy, institutional pharmacy, etc.) and profiles major competitors active in the industry.

INTRODUCTION xii

I. EXECUTIVE SUMMARY 1

II. MARKET ENVIRONMENT 4
General 4
Economic Factors 5
Demographic Patterns 8
Trends in Health Care 10
Medical Conditions 11
Chronic Conditions 12
Acute Conditions 14
Health Insurance Trends 16
National Health Expenditures 19
Medical Providers 23
Hospitals 24
Skilled Nursing Homes 24
Outpatient Facilities 25
Physicians 25
Patient Activity 26

III. PHARMACEUTICAL OVERVIEW 30
General 30
Regulation 31
Research & Development 33
Product Shipments 34
Central Nervous System Agents 35
Cardiovascular Agents 36
Anti-Infective Agents 36
Gastrointestinal Agents 37
Respiratory Agents 37
Biologicals 37
Hormones & Related Agents 38
Nutritional & Related Agents 38
Anti-Cancer Agents 39
Genito-Urinary Agents 39
Dermatological Agents 39
Dosage Formulations 40
Ethical Drugs 42
Over-the-Counter Drugs 44
Generic Drugs 46
Proprietary Pharmaceuticals 47

IV. PACKAGING MATERIALS 49
General 49
Basic Raw Materials 51
Plastic Resins 53
High Density Polyethylene 55
Polyethylene Terephthalate 55
Polypropylene 56
Low Density Polyethylene 56
Polyvinyl Chloride 57
Polystyrene 58
Other Plastic Resins 58
Paper & Paperboard 59
Aluminum Foil 60
Glass Materials 61
Other Basic Raw Materials 61
Semi-Finished Materials 63
Converted Paper & Paperboard 64
Plastic Film 65
Converted Foil 66
Other Semi-Finished Materials 67

V. PRODUCT OVERVIEW 69
General 69
Pharmaceutical Packaging Product Groups 71
Unit Dose Packaging 73
Historical Demand Patterns 75
US Trade 77
International Markets 79

VI. PHARMACEUTICAL CONTAINERS 82
General 82
Demand Patterns 83
Primary Pharmaceutical Containers 86
Blister Packaging 88
OTC Drug Packs 91
Ethical Drug Packs 94
Clinical Trial & Sample Drug Packs 96
Components 98
Producers 107
Plastic Bottles 107
Ovals, Squares & Rounds 108
Dispensing Bottles 111
Cans 112
Jars 113
Producers 114
Pouches & Strip Packs 115
Pouches 116
Strip Packs 117
Components 119
Producers 120
Prefillable Inhalers 121
Metered Dose Inhalers 122
Dry Powder Inhalers 125
Prefillable Syringes 129
Injectors 130
Cartridges 133
Tubes 135
Composite Tubes 137
Plastic Tubes 139
Metal Tubes 140
Parenteral Vials & Ampuls 141
Vials 142
Ampuls 147
Containers 149
Semi-Rigid Containers 151
Mini-Bags 153
Glass IV Containers 155
Other Primary Containers 156
Aerosol Containers 157
Glass Bottles & Jars 159
Paperboard Containers 160
All Other Primary Containers 161
Secondary Pharmaceutical Containers 162
Paperboard Containers 164
Prescription Dispensing Containers 167
Plastic Vials 169
Blister Packs 172
Glass Vials 173
Other Prescription Dispensing Containers 174
Shipping Containers 174
Corrugated Boxes 175
Folding Cartons 176
Other Secondary Pharmaceutical Containers 177
Trays 178
All Other Secondary Pharmaceutical Containers 179

VII. PHARMACEUTICAL PACKAGING ACCESSORIES 181
General 181
Pharmaceutical Caps & Closures 183
Child-Resistant Pharmaceutical Caps & Closures 185
Conventional Plastic Child-Resistant Closures 186
Specialty Plastic Child-Resistant Closures 188
Other Child-Resistant Closures 189
Standard Pharmaceutical Closures 190
Standard Plastic Closures 191
Standard Metal Closures 192
Pharmaceutical Dispensing Closures 193
Disc Closures 194
Pump-Type Closures 195
Turret Closures 195
Plastic Dropper Assemblies 195
Squeeze Tops 196
Other Dispensing Closures 196
Other Pharmaceutical Caps & Closures 197
Parenteral Stoppers 198
Flip-Top Closures 199
Paper, Foil & Laminated Lids 199
All Other Pharmaceutical Caps & Closures 199
Labels 200
RFID Features 202
Expanded Content Labels 203
Package Inserts 204
Other Pharmaceutical Packaging Accessories 206
Shrink Wrap & Bands 206
Inner Seals 208
All Other Pharmaceutical Packaging Accessories 209

VIII. MARKETS 210
General 210
Pharmaceutical Manufacturers 212
Contract Packaging 213
Retail Pharmacies 214
Institutional Pharmacies 216
Other Markets 217

IX. INDUSTRY STRUCTURE 219
General 219
Market Share 223
Competitive Strategies 225
Packaging Product Companies 226
Contract Packaging Firms 227
Mergers & Acquisitions 228
Licensing & Related Agreements 230
Marketing & Distribution 232
Product Development Activities 234
Manufacturing Requirements 235
Company Profiles 237
Alcan Incorporated 238
Alcoa Incorporated 241
Alexander (James) Corporation 243
Almac Sciences Limited 245
Altwood Roll Label Company, see Menasha
Amcor Limited 246
American Gasket & Rubber Company, see Tekni-Plex
American Health Packaging, see AmerisourceBergen
AmerisourceBergen Corporation 249
Anderson Packaging Incorporated, see AmerisourceBergen
Becton, Dickinson and Company 251
BERICAP Incorporated, see Amcor
Berk (O.) Company 252
Cardinal Health Incorporated 254
Carl-Zeiss-Stiftung 256
CCL Industries Incorporated 258
Clinical Trial Services Incorporated, see Almac Sciences
Comar Incorporated 261
Daetwyler Holding Incorporated 262
Gerresheimer Holdings GmbH 264
Helvoet Pharma NV, see Daetwyler Holding
Honeywell International Incorporated 266
HUECK FOLIEN GmbH & Company KG 267
Interglass Incorporated, see Alcan
Kimble Glass Incorporated, see Gerresheimer
Kloeckner Pentaplast GmbH & Company KG 269
MeadWestvaco Corporation 270
Menasha Corporation 272
New Jersey Packaging Incorporated, see Menasha
Owens-Illinois Incorporated 274
Pharmagraphics LLC 276
Rexam plc 277
Saint-Gobain 279
SCA Packaging North America, see Svenska Cellulosa
SCHOTT Pharmaceutical Packaging, see Carl-Zeiss-Stiftung
Sharp Corporation, see Superior Group
STEDIM SA 281
Superior Group Incorporated 283
Svenska Cellulosa AB 284
Tekni-Plex Incorporated 285
Thermosafe, see Svenska Cellulosa
3M Company 287
Tri-Seal, see Tekni-Plex
Tursso Companies Incorporated 289
Unicep Packaging Incorporated 290
Vetter Pharma-Fertigung GmbH & Company KG 291
West Pharmaceutical Services Incorporated 293
Other Pharmaceutical Packaging Companies 296 LIST OF TABLES

TABLE NUMBER PAGE

SECTION I -- EXECUTIVE SUMMARY
Summary Table 3

SECTION II -- MARKET ENVIRONMENT
1 Macroeconomic Indicators 8
2 Resident Population by Age Group 10
3 Medical Conditions 11
4 Chronic Conditions by Type 14
5 Acute Conditions by Type 16
6 National Health Expenditures 22
7 Medical Providers 24
8 Patient Activity 29

SECTION III -- PHARMACEUTICAL OVERVIEW
1 Pharmaceutical Shipments by Therapeutic Class 35
2 Pharmaceutical Shipments by Dosage Formulation 42
3 Ethical Pharmaceutical Shipments by Therapeutic Class 44
4 OTC Pharmaceutical Shipments by Therapeutic Class 46
5 Pharmaceutical Shipments by Commercial Status 48

SECTION IV -- PACKAGING MATERIALS
1 Pharmaceutical Packaging Material Consumption by Type 51
2 Pharmaceutical Packaging Raw Materials
Consumption by Type 52
3 Plastic Resin Consumption in Pharmaceutical Packaging 54
4 Semi-Finished Pharmaceutical Packaging Material
Consumption by Type 63
5 Converted Paper & Paperboard Consumption
in Pharmaceutical Packaging 65
6 Plastic Film Consumption in Pharmaceutical Packaging 66
7 Converted Foil Consumption in Pharmaceutical Packaging 67
8 Other Semi-Finished Material Consumption
in Pharmaceutical Packaging 68


(continued on next page) SECTION V -- PRODUCT OVERVIEW
1 Pharmaceutical Packaging Demand by Product Group 70
2 Unit Dose Pharmaceutical Packaging Demand by Product Group 75
3 Pharmaceutical Packaging - Demand Patterns, 1995-2005 77
4 US Trade in Pharmaceutical Packaging 79
5 World Pharmaceutical Packaging Demand 81

SECTION VI -- PHARMACEUTICAL CONTAINERS
1 Pharmaceutical Container Demand by Product Group 83
2 Primary Pharmaceutical Container Demand by Product Group 87
3 Pharmaceutical Blister Packaging Demand by Type 90
4 Plastic Pharmaceutical Bottle Demand by Type 108
5 Pharmaceutical Pouch & Strip Pack Demand by Type 116
6 Prefillable Inhaler Demand by Type 122
7 Prefillable Syringe Demand by Type 130
8 Medication Tube Demand by Type 137
9 Parenteral Vial & Ampul Demand by Type 142
10 IV Container Demand by Type 151
11 Other Primary Pharmaceutical Container Demand by Type 157
12 Secondary Pharmaceutical Container Demand
by Product Group 163
13 Secondary Paperboard Pharmaceutical Box Demand 167
14 Prescription (RX) Dispensing Container Demand by Type 169
15 Pharmaceutical Shipping Container Demand by Type 175
16 Other Secondary Pharmaceutical Container Demand by Type 178

SECTION VII -- PHARMACEUTICAL PACKAGING
ACCESSORIES
1 Pharmaceutical Packaging Accessory Demand
by Product Group 182
2 Pharmaceutical Cap & Closure Demand by Product Group 185
3 Child-resistant (CR) Pharmaceutical Cap & Closure
Demand by Type 186
4 Standard Pharmaceutical Cap & Closure Demand by Type 191


(continued on next page) 5 Pharmaceutical Dispensing Closure Demand 194
6 Other Pharmaceutical Cap & Closure Demand 197
7 Pharmaceutical Label Demand by Type 202
8 Pharmaceutical Package Insert Demand 205
9 Other Pharmaceutical Packaging Accessories Demand by Type 206

SECTION VIII -- MARKETS
1 Pharmaceutical Packaging Demand by Market 211
2 Pharmaceutical Manufacturing Market - Pharmaceutical
Packaging Demand 213
3 Contract Packaging Market - Pharmaceutical
Packaging Demand 214
4 Retail Pharmacy Market - Pharmaceutical Packaging Demand 215
5 Institutional Pharmacy Market - Pharmaceutical
Packaging Demand 217
6 Other Markets - Pharmaceutical Packaging Demand 218

SECTION IX -- INDUSTRY STRUCTURE
1 Pharmaceutical Packaging Sales by Company, 2005 220
2 Selected Acquisitions & Divestitures 229
3 Selected Cooperative Agreements 231

LIST OF CHARTS

CHART NUMBER PAGE

SECTION IV -- PACKAGING MATERIALS
1 Pharmaceutical Packaging Raw Materials Consumption
by Type, 2005 53
2 Semi-finished Pharmaceutical Packaging Material
Consumption by Type, 2005 64

SECTION V -- PRODUCT OVERVIEW
1 Pharmaceutical Packaging Product Demand by Type, 2005 73

SECTION VI -- PHARMACEUTICAL CONTAINERS
1 Primary Pharmaceutical Container Demand
by Product Group, 2005 88
2 Secondary Pharmaceutical Container Demand
by Product Group, 2005 164

SECTION VII -- PHARMACEUTICAL PACKAGING
ACCESSORIES
1 Pharmaceutical Packaging Accessory Demand
by Product Group, 2005 183

SECTION VIII -- MARKETS
1 Pharmaceutical Packaging Demand by Market, 2005 211

SECTION IX -- INDUSTRY STRUCTURE
1 Pharmaceutical Packaging Market Share by Company, 2005 225