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Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta

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Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta

Publication date: November 2011

Keywords : pain management

Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta Summary GBI Research, the leading business intelligence provider, has released its latest research, “Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta”, which provides insights into the global pain management therapeutics m...

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Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta

Summary

GBI Research, the leading business intelligence provider, has released its latest research, “Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta”, which provides insights into the global pain management therapeutics market and market forecasts until 2017. The report provides an in-depth analysis of the top eight therapeutic indications for which pain management drugs are often prescribed, which includes fibromyalgia, neuropathic pain, migraine, cancer pain, osteoarthritis pain, rheumatoid arthritis pain, low back pain and post-operative pain. The report also examines the global pain management therapeutics treatment usage patterns for the covered indications. In addition, the report also includes insights into the pain management therapeutics R&D pipeline.

The report is built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis by GBI Research’s team of industry experts.

The global pain management therapeutics market has huge potential for growth due to the large population that is affected by medically significant pain. The market is growing at a moderate growth rate, driven by the cancer pain, low back pain and post-operative pain relief markets. In 2010, the global pain management therapeutics market was estimated at $28.6 billion, representing a CAGR of 5.3% between 2002 and 2010. The post-operative pain relief market, with sales of $5.9 billion in 2010, accounted for one fifth of the total pain management therapeutics market. The low back pain market, with sales of $4.9 billion, was the second largest market segment, with a share of 17% of the worldwide pain management therapeutics market. The low back pain market is followed by the cancer pain and neuropathic pain relief markets, accounting for 16% each of the global pain management therapeutics market.

The global pain management market is driven by anticonvulsant Lyrica and anti-depressant Cymbalta, which are expected to expire in 2013. By 2017, the global pain management therapeutics market is forecast to generate sales of $35.1 billion, representing a CAGR of 3.0% between 2010 and 2017. Other blockbuster drugs that are likely to drive the market in the forecast period include UCB Group’s Vimpat (lacosamide), Teva’s Fentora (fentanyl), J&J’s Nucynta (tapentadol), Pfizer’s Remoxy (oxycodone hydrochloride) and Orexo’s Abstral (fentanyl).

Scope

- Data and analysis on the pain therapeutics market in the leading geographies of the world – the US, the UK, Germany, France, Italy, Spain, and Japan.
- Annualized market data for the pain management therapeutics market from 2002 to 2010, with forecasts to 2017.
- Market data on the therapeutic landscape, which covers fibromyalgia, neuropathic pain, migraine, cancer pain, osteoarthritis pain, rheumatoid arthritis pain, low back pain and post-operative pain therapeutics, including market size, market share, annual cost of therapy, sales volume and treatment usage patterns such as disease population and treated population.
- Key drivers and restraints that have had a significant impact on the market and on each indication.
- The competitive landscape of the global pain management therapeutics market, which includes companies such as Pfizer, Johnson & Johnson, Teva, Eli Lilly and several mid-size players such as Purdue Pharma, Endo Pharmaceuticals, and Forest Laboratories.
- Key M&A activities and Licensing Agreements that took place from 2005 to 2010 in the global pain management therapeutics market.

Reasons to buy

- Align your product portfolio to the markets with high growth potential.
- Develop market-entry and market expansion strategies by identifying the potential region and therapeutic segments poised for strong growth.
- Devise a more tailored country strategy through the understanding of key drivers and barriers of the region’s pain management therapeutics market.
- Develop key strategic initiatives by understanding the key focus areas and top selling pain management therapeutics molecules of leading companies.
- Accelerate and strengthen your market position by identifying key companies for mergers, acquisitions and strategic partnerships.

Global General Medicine And Specialty Medicine Industry

1 Table of Contents
1 Table of Contents 3
1.1 List of Tables 7
1.2 List of Figures 11
2 Pain Management Therapeutics Market - Introduction 17
2.1 GBI Research Report Guidance 18
3 Pain Management Therapeutics Market - Market Overview 19
3.1 Introduction 19
3.2 WHO (World Health Organization) Pain Ladder 21
3.3 Risk Evaluation and Mitigation Strategy (REMS) 22
3.4 Revenue 23
3.5 Major Marketed Pain Management Drugs 24
3.5.1 Lyrica (pregabalin) 25
3.5.2 Cymbalta (duloxetine) 26
3.5.3 Celebrex (celecoxib) 26
3.5.4 Voltaren Gel (diclofenac sodium) 27
3.5.5 Imitrex(sumatriptan succinate) 27
3.5.6 Savella (milnacipran hydrochloride) 28
3.5.7 Lidoderm (lidocaine patch) 28
3.5.8 Qutenza (capsaicin) 28
3.5.9 Zomig (zolmitriptan) 29
3.5.10 Maxalt (rizatriptan benzoate) 29
3.6 Annual Cost of Therapy 30
3.7 Treatment Usage Patterns 31
3.7.1 Diseased Population 33
3.7.2 Treatment Seeking Population 34
3.7.3 Diagnosed Population 35
3.7.4 Prescription Population 36
3.8 Drivers and Restraints of the Pain Management Therapeutics Market 37
3.8.1 Drivers 37
3.8.2 Restraints 38
4 Pain Management Therapeutics Market - Therapeutic Landscape 39
4.1 Pain Management Therapeutics Market for Fibromyalgia 39
4.1.1 Introduction 39
4.1.2 Revenue 40
4.1.3 Branded vs. Generic Share 41
4.1.4 Annual Cost of Therapy 42
4.1.5 Treatment Flow Algorithm 43
4.1.6 Treatment Usage Patterns 44
4.1.7 Geographical Segmentation 50
4.1.8 Drivers and Restraints for the Fibromyalgia Market 53
4.1.9 Restraints for the Fibromyalgia Pain Relief Market 54
4.2 Pain Management Therapeutics for Neuropathic Pain 54
4.2.1 Introduction 54
4.2.2 Revenue 55
4.2.3 Branded Vs Generic Share 56
4.2.4 Annual Cost of Therapy 57
4.2.5 Treatment Flow Algorithm 58
4.2.6 Treatment Usage Patterns 59
4.2.7 Geographical Segmentation 64
4.2.8 Drivers and Restraints for the Neuropathic Pain Market 66
4.2.9 Drivers 67
4.2.10 Restraints 67
4.3 Pain Management Therapeutics Market for Migraine 68
4.3.1 Introduction 68
4.3.2 Revenue 68
4.3.3 Branded Vs Generic Share 69
4.3.4 Annual Cost of Therapy 70
4.3.5 Treatment Flow Algorithm 72
4.3.6 Treatment Usage Patterns 73
4.3.7 Geographical Segmentation 79
4.3.8 Drivers and Restraints for the Migraine Market 81
4.3.9 Drivers 82
4.3.10 Restraints 82
4.4 Pain Management Therapeutics Market for Cancer Pain 82
4.4.1 Introduction 82
4.4.2 Revenue 83
4.4.3 Branded Vs Generic Share 85
4.4.4 Annual Cost of Therapy 86
4.4.5 Treatment Flow Algorithm 87
4.4.6 Treatment Usage Patterns 88
4.4.7 Geographical Segmentation 96
4.4.8 Drivers and Restraints for the Cancer Pain Market 98
4.4.9 Drivers 99
4.4.10 Restraints 99
4.5 Pain Management Therapeutics Market for Osteoarthritis Pain 100
4.5.1 Introduction 100
4.5.2 Revenue 101
4.5.3 Branded vs. Generic Share 102
4.5.4 Annual Cost of Therapy 103
4.5.5 Treatment Flow Algorithm 104
4.5.6 Treatment Usage Patterns 105
4.5.7 Geographical Segmentation 110
4.5.8 Drivers and Restraints for the Osteoarthritis Pain Market 112
4.5.9 Drivers 113
4.5.10 Restraints 113
4.6 Pain Management Therapeutics Market for Rheumatoid Arthritis Pain 114
4.6.1 Introduction 114
4.6.2 Revenue 114
4.6.3 Branded vs. Generic Share 116
4.6.4 Annual Cost of Therapy 117
4.6.5 Treatment Flow Algorithm 118
4.6.6 Treatment Usage Patterns 119
4.6.7 Geographical Segmentation 124
4.6.8 Drivers and Restraints for the Rheumatoid Arthritis Market 126
4.6.9 Drivers 127
4.6.10 Restraints 127
4.7 Pain Management Therapeutics Market for Low Back Pain 127
4.7.1 Introduction 127
4.7.2 Revenue 128
4.7.3 Branded vs. Generic Share 129
4.7.4 Annual Cost of Therapy 130
4.7.5 Treatment Flow Algorithm 131
4.7.6 Treatment Usage Patterns 132
4.7.7 Geographical Segmentation 138
4.7.8 Drivers and Restraints for the Low Back Pain Market 140
4.7.9 Drivers 141
4.7.10 Restraints 141
4.8 Pain Management Therapeutics Market for Post-Operative Pain 141
4.8.1 Introduction 141
4.8.2 Revenue 143
4.8.3 Branded vs. Generic Share 144
4.8.4 Annual Cost of Therapy 145
4.8.5 Treatment Flow Algorithm 146
4.8.6 Treatment Usage Patterns 147
4.8.7 Geographical Segmentation 152
4.8.8 Drivers and Restraints for the Post-Operative Pain Market 154
4.8.9 Drivers 155
4.8.10 Restraints 155
5 Pain Management Therapeutics Market - Geographical Landscape 156
5.1 The US 159
5.1.1 Revenue 159
5.1.2 Annual Cost of Therapy 161
5.1.3 Treatment Usage Patterns 162
5.2 Top Five Countries in Europe 168
5.2.1 Revenue 168
5.2.2 Annual Cost of Therapy 169
5.2.3 Treatment Usage Patterns 170
5.3 Japan 176
5.3.1 Revenue 176
5.3.2 Annual Cost of Therapy 177
5.3.3 Treatment Usage Patterns 178
6 Pain Management Therapeutics Market - Pipeline Analysis 183
6.1 Introduction 183
6.1.1 Research and Development Pipeline – Fibromyalgia 185
6.1.2 Research and Development Pipeline – Neuropathic Pain 187
6.1.3 Research and Development Pipeline – Migraine 193
6.1.4 Research and Development Pipeline – Cancer Pain 196
6.1.5 Research and Development Pipeline – Osteoarthritis Pain 198
6.1.6 Research and Development Pipeline – Low Back Pain 200
6.1.7 Research and Development Pipeline – Post-Operative Pain 202
6.2 Profiles of Key Late-Stage Drugs in the Pain Management Therapeutics Market 204
6.2.1 Vimpat (Lacosamide) 204
6.2.2 Droxidopa 205
6.2.3 Civanex 205
6.2.4 Zelrix 206
6.2.5 Sativex 206
7 Pain Management Therapeutics Market - Competitive Landscape 208
7.1 Competitive Profiling 208
7.1.1 Pfizer Inc 208
7.1.2 Johnson & Johnson 210
7.1.3 Endo Pharmaceuticals 212
7.1.4 Forest Laboratories 214
7.1.5 Eli Lilly 215
7.1.6 Teva Pharmaceuticals (Cephalon, Inc.) 216
7.1.7 Purdue Pharma 217
8 Pain Management Therapeutics Market - Strategic Consolidations 218
8.1 Overview 218
8.1.1 M&A Deals by Year 218
8.1.2 M&A Deals by Indication 219
8.1.3 M&A Deals by Geography 220
8.1.4 M&A Deals by Value ($) 221
8.2 R&D Licensing Agreements 224
8.2.1 Deals by Indication 225
8.2.2 Deals by Geography 226
8.2.3 Deals by Phase 227
8.2.4 Deals by Value ($) 228
8.2.5 Deals by Type 229
8.3 Co-Development Deals 231
8.3.1 Deals by Indication 231
8.3.2 Deals by Geography 232
9 Pain Management Therapeutics Market - Appendix 234
9.1 Market Definitions 234
9.2 Abbreviations 234
9.3 Research Methodology 235
9.3.1 Coverage 235
9.3.2 Secondary Research 235
9.3.3 Primary Research 236
9.3.4 Geographical Landscape 239
9.3.5 Pipeline Analysis 239
9.3.6 Competitive Landscape 239
9.3.7 Expert Panel Validation 239
9.4 Contact Us 239
9.5 Disclaimer 239
9.6 Sources 240

1.1 List of Tables

Table 1: Pain Management Therapeutics Market, Global, Revenue ($bn), 2002–2010 23
Table 2: Pain Management Therapeutics Market, Global, Revenue Forecasts ($bn), 2010–2017 23
Table 3: Pain Management Therapeutics Market, Global, Revenue of Top Selling Pain Management Drugs ($m), 2007–2010 24
Table 4: Pain Management Therapeutics Market, Major Marketed Pain Management Drugs Profile, 2010 25
Table 5: Pain Management Therapeutics Market, Global, Annual Cost of Therapy ($), 2002–2010 30
Table 6: Pain Management Therapeutics Market, Global, Annual Cost of Therapy ($), 2010–2017 30
Table 7: Pain Management Therapeutics Market, Global, Treatment Usage Patterns (million), 2002–2010 32
Table 8: Pain Management Therapeutics Market, Global, Treatment Usage Patterns (million), 2010–2017 32
Table 9: Pain Management Therapeutics Market, Global, Fibromyalgia, Revenue ($m), 2002–2010 40
Table 10: Pain Management Therapeutics Market, Global, Fibromyalgia, Revenue Forecasts ($m), 2010–2017 41
Table 11: Pain Management Therapeutics Market, Global, Fibromyalgia, Annual Cost of Therapy ($), 2002–2010 42
Table 12: Pain Management Therapeutics Market, Global, Fibromyalgia, Annual Cost of Therapy ($), 2010–2017 42
Table 13: Pain Management Therapeutics Market, Global, Fibromyalgia, Treatment Usage Patterns (million), 2002–2010 44
Table 14: Pain Management Therapeutics Market, Global, Fibromyalgia, Treatment Usage Patterns (million), 2010–2017 45
Table 15: Pain Management Therapeutics Market, Global, Fibromyalgia, Geographical Segmentation ($m), 2002–2010 51
Table 16: Pain Management Therapeutics Market, Global, Fibromyalgia, Market Geographical Segmentation ($m), 2010–2017 52
Table 17: Pain Management Therapeutics Market, Global, Neuropathic Pain Revenue ($m), 2002–2010 55
Table 18: Pain Management Therapeutics Market, Global, Neuropathic Pain Revenue Forecasts ($m), 2010–2017 55
Table 19: Pain Management Therapeutics Market, Global, Neuropathic Pain, Annual Cost of Therapy ($), 2002–2010 57
Table 20: Pain Management Therapeutics Market, Global, Neuropathic Pain, Annual Cost of Therapy ($), 2010–2017 57
Table 21: Pain Management Therapeutics Market, Global, Neuropathic Pain, Treatment Usage Patterns (million), 2002–2010 59
Table 22: Pain Management Therapeutics Market, Global, Neuropathic Pain, Treatment Usage Patterns (million), 2010–2017 60
Table 23: Pain Management Therapeutics Market, Global, Neuropathic Pain, Geographical Segmentation ($m), 2002–2010 65
Table 24: Pain Management Therapeutics Market, Global, Neuropathic Pain, Geographical Segmentation ($m), 2010–2017 66
Table 25: Pain Management Therapeutics Market, Global, Migraine, Revenue ($m), 2002–2010 69
Table 26: Pain Management Therapeutics Market, Global, Migraine, Revenue Forecasts ($m), 2010–2017 69
Table 27: Pain Management Therapeutics Market, Global, Migraine, Annual Cost of Therapy ($), 2002–2010 70
Table 28: Pain Management Therapeutics Market, Global, Migraine, Annual Cost of Therapy ($), 2010–2017 70
Table 29: Pain Management Therapeutics Market, Global, Migraine, Treatment Usage Patterns (million), 2002–2010 74
Table 30: Pain Management Therapeutics Market, Global, Migraine, Treatment Usage Patterns (million), 2010–2017 74
Table 31: Pain Management Therapeutics Market, Global, Migraine, Geographical Segmentation ($m), 2002–2010 80
Table 32: Pain Management Therapeutics Market, Global, Migraine, Geographical Segmentation ($m), 2010–2017 81
Table 33: Pain Management Therapeutics Market, Global, Cancer Pain, Revenue ($m), 2002–2010 83
Table 34: Pain Management Therapeutics Market, Global, Cancer Pain, Revenue Forecasts ($m), 2010–2017 84
Table 35: Pain Management Therapeutics Market, Global, Cancer Pain, Annual Cost of Therapy ($), 2002–2010 86
Table 36: Pain Management Therapeutics Market, Global, Cancer Pain, Annual Cost of Therapy ($), 2010–2017 87
Table 37: Pain Management Therapeutics Market, Global, Cancer Pain, Treatment Usage Patterns (million), 2002–2010 89
Table 38: Pain Management Therapeutics Market, Global, Cancer Pain, Treatment Usage Patterns (million), 2010–2017 89
Table 39: Pain Management Therapeutics Market, Global, Cancer Pain, Geographical Segmentation ($m), 2002–2010 97
Table 40: Pain Management Therapeutics Market, Global, Cancer Pain, Geographical Segmentation ($m), 2010–2017 98
Table 41: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Revenue ($m), 2002–2010 101
Table 42: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Revenue Forecasts ($m), 2010–2017 102
Table 43: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Annual Cost of Therapy ($), 2002–2010 103
Table 44: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Annual Cost of Therapy ($), 2010–2017 103
Table 45: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Treatment Usage Patterns (million), 2002–2010 105
Table 46: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Treatment Usage Patterns (million), 2010–2017 106
Table 47: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Geographical Segmentation ($m), 2002–2010 111
Table 48: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Geographical Segmentation ($m), 2010–2017 112
Table 49: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Revenue ($m), 2002–2010 115
Table 50: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Revenue Forecasts ($m), 2010–2017 115
Table 51: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Annual Cost of Therapy ($), 2002–2010 117
Table 52: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Annual Cost of Therapy ($), 2010–2017 117
Table 53: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Treatment Usage Patterns (Thousands), 2002–2010 119
Table 54: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Treatment Usage Patterns (Thousands), 2010–2017 120
Table 55: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Geographical Segmentation ($m), 2002–2010 125
Table 56: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Geographical Segmentation ($m), 2010–2017 126
Table 57: Pain Management Therapeutics Market, Global, Low Back Pain, Revenue ($m), 2002–2010 129
Table 58: Pain Management Therapeutics Market, Global, Low Back Pain, Revenue Forecasts ($m), 2010–2017 129
Table 59: Pain Management Therapeutics Market, Global, Low Back Pain, Annual Cost of Therapy ($), 2002–2010 130
Table 60: Pain Management Therapeutics Market, Global, Low Back Pain, Annual Cost of Therapy ($), 2010–2017 130
Table 61: Pain Management Therapeutics Market, Global, Low Back Pain, Treatment Usage Patterns (million), 2002–2010 133
Table 62: Pain Management Therapeutics Market, Global, Low Back Pain, Treatment Usage Patterns (million), 2010–2017 133
Table 63: Pain Management Therapeutics Market, Global, Low Back Pain, Geographical Segmentation ($m), 2002–2010 139
Table 64: Pain Management Therapeutics Market, Global, Low Back Pain, Geographical Segmentation ($m), 2010–2017 140
Table 65: Pain Management Therapeutics Market, Global, Post-Operative Pain, Revenue ($bn), 2002–2010 143
Table 66: Pain Management Therapeutics Market, Global, Post-Operative Pain, Revenue Forecasts ($bn), 2010–2017 143
Table 67: Pain Management Therapeutics Market, Global, Post-Operative Pain, Annual Cost of Therapy ($), 2002–2010 145
Table 68: Pain Management Therapeutics Market, Global, Post-Operative Pain, Annual Cost of Therapy ($), 2010–2017 145
Table 69: Pain Management Therapeutics Market, Global, Post-Operative Pain, Treatment Usage Patterns (million), 2002–2010 147
Table 70: Pain Management Therapeutics Market, Global, Post-Operative Pain, Treatment Usage Patterns (million), 2010–2017 148
Table 71: Pain Management Therapeutics Market, Global, Post-Operative Pain, Geographical Segmentation ($m), 2002–2010 153
Table 72: Pain Management Therapeutics Market, Global, Post-Operative Pain, Geographical Segmentation ($m), 2010–2017 154
Table 73: Pain Management Therapeutics Market, Global, Revenues by Geography ($bn), 2002–2010 158
Table 74: Pain Management Therapeutics Market, Global, Revenues by Geography ($bn), 2010–2017 158
Table 75: Pain Management Therapeutics Market, The US, Revenues ($), 2002–2010 159
Table 76: Pain Management Therapeutics Market, The US, Revenue Forecasts ($), 2010–2017 160
Table 77: Pain Management Therapeutics Market, The US, Annual Cost of Therapy ($), 2002–2010 161
Table 78: Pain Management Therapeutics Market, The US, Annual Cost of Therapy ($), 2010–2017 161
Table 79: Pain Management Therapeutics Market, The US, Treatment Usage Pattern (million), 2002–2010 162
Table 80: Pain Management Therapeutics Market, The US, Treatment Usage Pattern (million), 2010–2017 163
Table 81: Pain Management Therapeutics Market, Top Five Countries in Europe, Revenues ($bn), 2002–2010 168
Table 82: Pain Management Therapeutics Market, Top Five Countries in Europe, Revenue Forecasts ($bn), 2010–2017 168
Table 83: Pain Management Therapeutics Market, Top Five Countries in Europe, Annual Cost of Therapy ($), 2002–2010 169
Table 84: Pain Management Therapeutics Market, Top Five Countries in Europe, Annual Cost of Therapy ($), 2010–2017 169
Table 85: Pain Management Therapeutics Market, Top Five Countries in Europe, Treatment Usage Patterns (million), 2002–2010 170
Table 86: Pain Management Therapeutics Market, Top Five Countries in Europe, Treatment Usage Patterns (million), 2010–2017 171
Table 87: Pain Management Therapeutics Market, Japan, Revenues ($bn), 2002–2010 176
Table 88: Pain Management Therapeutics Market, Japan, Revenue Forecasts ($bn), 2010–2017 176
Table 89: Pain Management Therapeutics Market, Japan, Annual Cost of Therapy ($), 2002–2010 177
Table 90: Pain Management Therapeutics Market, Japan, Annual Cost of Therapy ($), 2010–2017 177
Table 91: Pain Management Therapeutics Market, Japan, Treatment Usage Pattern (million), 2002–2010 178
Table 92: Pain Management Therapeutics Market, Japan, Treatment Usage Pattern (million), 2010–2017 179
Table 93: Pain Management Therapeutics, Fibromyalgia R&D Pipeline, April 2011 186
Table 94: Pain Management Therapeutics, Neuropathic Pain R&D Pipeline, April 2011 188
Table 95: Pain Management Therapeutics, Migraine R&D Pipeline, April 2011 194
Table 96: Pain Management Therapeutics, Cancer Pain R&D Pipeline, April 2011 197
Table 97: Pain Management Therapeutics, Osteoarthritis Pain R&D Pipeline, April 2011 199
Table 98: Pain Management Therapeutics, Low Back Pain R&D Pipeline, April 2011 201
Table 99: Pain Management Therapeutics, Post-Operative Pain R&D Pipeline, April 2011 203
Table 100:Pain Management Therapeutics Market, Global, Major M&A Deals, 2010–2011 222
Table 101:Pain Management Therapeutics Market, Global Major Licensing Deals, 2010-2011 230
Table 102:Pain Management Therapeutics Market, Global, Major Co-Development Deals, 2010-2011 233

1.2 List of Figures

Figure 1: Pain Management Therapeutics Market, Global Revenue by Indication (%), 2010 and 2017 19
Figure 2: Pain Management Therapeutics Market, WHO 3-Step Ladder for Pain Management, 2011 20
Figure 3: Pain Management Therapeutics Market, Opioids – Adverse Effects, 2011 21
Figure 4: Pain Management Therapeutics Market, Global, Revenue Forecasts ($bn), 2002–2017 22
Figure 5: Pain Management Therapeutics Market, Global Revenue of Top Selling Pain Management Drugs ($m), 2007–2010 23
Figure 6: Pain Management Therapeutics Market, Global, Annual Cost of Therapy ($), 2002–2017 29
Figure 7: Pain Management Therapeutics Market, Global Therapeutic Usage Patterns, 2002–2017 30
Figure 8: Pain Management Therapeutics Market, Global Diseased Population (million), 2002–2017 32
Figure 9: Pain Management Therapeutics Market, Global Treatment Seeking Population (million), 2002–2017 33
Figure 10: Pain Management Therapeutics Market, Global Diagnosed Population (million), 2002–2017 34
Figure 11: Pain Management Therapeutics Market, Global Prescription Population (million), 2002–2017 35
Figure 12: Pain Management Therapeutics Market, Drivers and Restraints, 2010 36
Figure 13: Pain Management Therapeutics Market, Global, Fibromyalgia, Revenue Forecasts ($m), 2002–2017 39
Figure 14: Pain Management Therapeutics Market, Global, Fibromyalgia, Branded Vs Generic Share (%), 2010, 2017 40
Figure 15: Pain Management Therapeutics Market, Global, Fibromyalgia, Annual Cost of Therapy ($), 2002–2017 41
Figure 16: Pain Management Therapeutics Market, Global, Fibromyalgia, Treatment Algorithm 42
Figure 17: Pain Management Therapeutics Market, Global, Fibromyalgia, Treatment Usage Pattern (millions), 2002–2017 43
Figure 18: Pain Management Therapeutics Market, Global, Fibromyalgia, Diseased Population (million), 2002–2017 45
Figure 19: Pain Management Therapeutics Market, Global, Fibromyalgia, Treatment Seeking Population (million), 2002–2017 46
Figure 20: Pain Management Therapeutics Market, Global, Fibromyalgia, Diagnosis Population (million), 2002–2017 47
Figure 21: Pain Management Therapeutics Market, Global, Fibromyalgia, Prescription Population (million), 2002–2017 48
Figure 22: Pain Management Therapeutics Market, Global, Fibromyalgia, Segmentation by Geography (%), 2010 and 2017 49
Figure 23: Pain Management Therapeutics Market, Global, Fibromyalgia, Geographical Segmentation ($m), 2002–2017 50
Figure 24: Pain Management Therapeutics Market, Fibromyalgia, Drivers and Restraints, 2010 52
Figure 25: Pain Management Therapeutics Market, Global, Neuropathic Pain, Revenue Forecasts ($m), 2002–2017 54
Figure 26: Pain Management Therapeutics Market, Global, Neuropathic Pain, Branded Vs Generic Share (%), 2010, 2017 55
Figure 27: Pain Management Therapeutics Market, Global, Neuropathic Pain, Annual Cost of Therapy ($), 2002–2017 56
Figure 28: Pain Management Therapeutics Market, Global, Neuropathic Pain Treatment Algorithm 57
Figure 29: Pain Management Therapeutics Market, Global, Neuropathic Pain, Treatment Usage Patterns (million), 2002–2017 58
Figure 30: Pain Management Therapeutics Market, Global, Neuropathic Pain, Diseased Population (million), 2002–2017 59
Figure 31: Pain Management Therapeutics Market, Global, Neuropathic Pain, Treatment Seeking Population (million), 2002–2017 60
Figure 32: Pain Management Therapeutics Market, Global, Neuropathic Pain, Diagnosis Population (million), 2002–2017 61
Figure 33: Pain Management Therapeutics Market, Global, Neuropathic Pain, Prescription Population (million), 2002–2017 62
Figure 34: Pain Management Therapeutics Market, Global, Neuropathic Pain, Segmentation by Geography, 2010 and 2017 63
Figure 35: Pain Management Therapeutics Market, Global, Neuropathic Pain, Geographical Segmentation ($m), 2002–2017 64
Figure 36: Pain Management Therapeutics Market, Global, Neuropathic Pain Drivers and Restraints, 2010 65
Figure 37: Pain Management Therapeutics Market, Global, Migraine, Revenue Forecasts ($m), 2002–2017 67
Figure 38: Pain Management Therapeutics Market, Global, Migraine, Generic Share (%), 2010, 2017 68
Figure 39: Pain Management Therapeutics Market, Global, Migraine, Annual Cost of Therapy ($), 2002–2017 69
Figure 40: Pain Management Therapeutics Market, Global, Migraine, Treatment Algorithm 71
Figure 41: Pain Management Therapeutics Market, Global, Migraine, Treatment Usage Patterns (million), 2002–2017 72
Figure 42: Pain Management Therapeutics Market, Global, Migraine, Diseased Population (million), 2002–2017 74
Figure 43: Pain Management Therapeutics Market, Global, Migraine, Treatment Seeking Population (million), 2002–2017 75
Figure 44: Pain Management Therapeutics Market, Global, Migraine, Diagnosis Population (million), 2002–2017 76
Figure 45: Pain Management Therapeutics Market, Global, Migraine, Prescription Population (million), 2002–2017 77
Figure 46: Pain Management Therapeutics Market, Global, Migraine, Segmentation by Geography, 2010 and 2017 78
Figure 47: Pain Management Therapeutics Market, Global, Migraine, Geographical Segmentation ($m), 2002–2017 79
Figure 48: Pain Management Therapeutics Market, Migraine, Drivers and Restraints, 2010 80
Figure 49: Pain Management Therapeutics Market, Global, Cancer Pain, Revenue Forecasts ($m), 2002–2017 82
Figure 50: Pain Management Therapeutics Market, Global, Cancer Pain, Branded Vs Generic Share (%), 2010, 2017 84
Figure 51: Pain Management Therapeutics Market, Global, Cancer Pain, Annual Cost of Therapy ($), 2002–2017 85
Figure 52: Pain Management Therapeutics Market, Global, Cancer Pain, Treatment Algorithm 86
Figure 53: Pain Management Therapeutics Market, Global, Cancer Pain, Treatment Usage Patterns (million), 2002–2017 87
Figure 54: Pain Management Therapeutics Market, Global, Cancer Pain, Diseased Population (million), 2002–2017 89
Figure 55: Pain Management Therapeutics Market, Global, Cancer Pain, Treatment Seeking Population (million), 2002–2017 90
Figure 56: Pain Management Therapeutics Market, Global, Cancer Pain, Diagnosis Population (million), 2002–2017 91
Figure 57: Pain Management Therapeutics Market, WHO 3-Step Ladder for Cancer Pain Management 92
Figure 58: Pain Management Therapeutics Market, Global, Cancer Pain, Prescription Population (million), 2002–2017 94
Figure 59: Pain Management Therapeutics Market, Global, Cancer Pain, Segmentation by Geography, 2010 and 2017 95
Figure 60: Pain Management Therapeutics Market, Global, Cancer Pain, Geographical Segmentation ($m), 2002–2017 96
Figure 61: Pain Management Therapeutics Market, Global, Cancer Pain, Drivers and Restraints, 2010 97
Figure 62: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Revenue Forecasts ($m), 2002–2017 100
Figure 63: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Branded Vs Generic Share (%), 2010, 2017 101
Figure 64: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Annual Cost of Therapy ($), 2002–2017 102
Figure 65: Pain Management Therapeutics Market, Global, Osteoarthritis Pain Treatment Algorithm 103
Figure 66: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Treatment Usage Patterns (million), 2002–2017 104
Figure 67: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Diseased Population (million), 2002–2017 105
Figure 68: Pain Management Therapeutics Market, Global, Osteoarthritis Pain Treatment Seeking Population (million), 2002–2017 106
Figure 69: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Diagnosis Population (million), 2002–2017 107
Figure 70: Pain Management Therapeutics Market, Global, Osteoarthritis Pain Prescription Population (million), 2002–2017 108
Figure 71: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Segmentation by Geography (%), 2010 and 2017 109
Figure 72: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Geographical Segmentation ($m), 2002–2017 110
Figure 73: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Drivers and Restraints, 2010 111
Figure 74: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Revenue Forecasts ($m), 2002–2017 113
Figure 75: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Branded Vs Generic Share (%), 2010, 2017 115
Figure 76: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Annual Cost of Therapy ($), 2002–2017 116
Figure 77: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Treatment Algorithm 117
Figure 78: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Treatment Usage Patterns (million), 2002–2017 118
Figure 79: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Diseased Population (million), 2002–2017 119
Figure 80: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Treatment Seeking Population (million), 2002–2017 120
Figure 81: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Diagnosis Population (million), 2002–2017 121
Figure 82: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Prescription Population (million), 2002–2017 122
Figure 83: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Segmentation by Geography (%), 2010 and 2017 123
Figure 84: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Geographical Segmentation ($m), 2002–2017 124
Figure 85: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain Drivers and Restraints, 2010 125
Figure 86: Pain Management Therapeutics Market, Global, Low Back Pain, Revenue Forecasts ($m), 2002–2017 127
Figure 87: Pain Management Therapeutics Market, Global, Low Back Pain, Branded Vs Generic Share (%), 2010 and 2017 128
Figure 88: Pain Management Therapeutics Market, Global, Low Back Pain, Annual Cost of Therapy ($), 2002–2017 129
Figure 89: Pain Management Therapeutics Market, Global, Low Back Pain, Treatment Algorithm 130
Figure 90: Pain Management Therapeutics Market, Global, Low Back Pain, Treatment Usage Patterns (million), 2002–2017 131
Figure 91: Pain Management Therapeutics Market, Global, Low Back Pain, Diseased Population (million), 2002–2017 133
Figure 92: Pain Management Therapeutics Market, Global, Low Back Pain, Treatment Seeking Population (million), 2002–2017 134
Figure 93: Pain Management Therapeutics Market, Global, Low Back Pain, Diagnosis Population (million), 2002–2017 135
Figure 94: Pain Management Therapeutics Market, Global, Low Back Pain, Prescription Population (million), 2002–2017 136
Figure 95: Pain Management Therapeutics Market, Global, Low Back Pain, Segmentation by Geography (%), 2010 and 2017 137
Figure 96: Pain Management Therapeutics Market, Global, Low Back Pain, Geographical Segmentation ($m), 2002–2017 138
Figure 97: Pain Management Therapeutics Market, Global, Low Back Pain Drivers and Restraints, 2010 139
Figure 98:Pain Management Therapeutics Market, WFSA 3-Step Ladder for Pain Management 141
Figure 99:Pain Management Therapeutics Market, Global, Post-Operative Pain, Revenue Forecasts ($m), 2002–2017 142
Figure 100:Pain Management Therapeutics Market, Global, Post-Operative Pain, Branded vs. Generic Share (%), 2010 and 2017 143
Figure 101:Pain Management Therapeutics Market, Global, Post-Operative Pain, Annual Cost of Therapy ($), 2002–2017 144
Figure 102:Pain Management Therapeutics Market, Global, Post-Operative Pain Treatment Algorithm 145
Figure 103:Pain Management Therapeutics Market, Global, Post-Operative Pain, Treatment Usage Patterns (million), 2002–2017 146
Figure 104:Pain Management Therapeutics Market, Global, Post-Operative Pain, Diseased Population (million), 2002–2017 147
Figure 105:Pain Management Therapeutics Market, Global, Post-Operative Pain, Treatment Seeking Population (million), 2002–2017 148
Figure 106:Pain Management Therapeutics Market, Global, Post-Operative Pain, Diagnosis Population (million), 2002–2017 149
Figure 107:Pain Management Therapeutics Market, Global, Post-Operative Pain, Prescription Population (million), 2002–2017 150
Figure 108:Pain Management Therapeutics Market, Global, Post-Operative Pain, Segmentation by Geography (%), 2010 and 2017 151
Figure 109:Pain Management Therapeutics Market, Global, Post-Operative Pain, Geographical Segmentation ($m), 2002–2017 152
Figure 110:Pain Management Therapeutics Market, Global, Post-Operative Pain Drivers and Restraints, 2010 153
Figure 111:Pain Management Therapeutics Market, Global, Market Share by Geography (%), 2010 and 2017 155
Figure 112:Pain Management Therapeutics Market, Global, Revenues by Geography ($bn), 2002–2017 156
Figure 113:Pain Management Therapeutics Market, The US, Revenue Forecasts ($), 2002–2017 158
Figure 114:Pain Management Therapeutics Market, The US, Annual Cost of Therapy ($), 2002–2017 160
Figure 115:Pain Management Therapeutics Market, The US, Treatment Usage Pattern (million), 2002–2017 161
Figure 116: Pain Management Therapeutics Market, The US, Diseased Population (million), 2002–2017 163
Figure 117:Pain Management Therapeutics Market, The US, Treatment Seeking Population (million), 2002–2017 164
Figure 118:Pain Management Therapeutics Market, The US, Diagnosed Population (million), 2002–2017 165
Figure 119:Pain Management Therapeutics Market, The US, Prescription Population (million), 2002–2017 166
Figure 120:Pain Management Therapeutics Market, Top Five Countries in Europe, Revenue Forecasts ($bn), 2002–2017 167
Figure 121:Pain Management Therapeutics Market, Top Five Countries in Europe, Annual Cost of Therapy ($), 2002–2017 168
Figure 122:Pain Management Therapeutics Market, Top Five Countries in Europe, Treatment Usage Patterns (million), 2002–2017 169
Figure 123:Pain Management Therapeutics Market, Top Five Countries in Europe, Diseased Population (million), 2002–2017 171
Figure 124:Pain Management Therapeutics Market, Top Five Countries in Europe, Treatment Seeking Population (million), 2002–2017 172
Figure 125:Pain Management Therapeutics Market, Top Five Countries in Europe, Diagnosed Population (million), 2002–2017 173
Figure 126:Pain Management Therapeutics Market, Top Five Countries in Europe, Prescription Population (million), 2002–2017 174
Figure 127:Pain Management Therapeutics Market, Japan, Revenue Forecasts ($bn), 2002–2017 175
Figure 128:Pain Management Therapeutics Market, Japan, Annual Cost of Therapy ($), 2002–2017 176
Figure 129:Pain Management Therapeutics Market, Japan, Treatment Usage Pattern (million), 2002–2017 177
Figure 130:Pain Management Therapeutics Market, Japan, Diseased Population (million), 2002–2017 178
Figure 131:Pain Management Therapeutics Market, Japan, Treatment Seeking Population (million), 2002–2017 179
Figure 132:Pain Management Therapeutics Market, Japan, Diagnosis Population (million), 2002–2017 180
Figure 133:Pain Management Therapeutics Market, Japan, Prescription Population (million), 2002–2017 181
Figure 134:Pain Management Therapeutics Market, Global, R&D Pipeline by Indication (%), April 2011 182
Figure 135:Pain Management Therapeutics Marke

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