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Periodontal Disease – Pipeline Review, H1 2013

  • February 2013
  • -
  • Global Markets Direct
  • -
  • 51 pages

Periodontal Disease – Pipeline Review, H1 2013

Summary

Global Markets Direct’s, 'Periodontal Disease - Pipeline Review, H1 2013', provides an overview of the indication’s therapeutic pipeline. This report provides information on the therapeutic development for Periodontal Disease, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Periodontal Disease. Periodontal Disease - Pipeline Review, Half Year is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- A snapshot of the global therapeutic scenario for Periodontal Disease.
- A review of the Periodontal Disease products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
- Coverage of products based on various stages of development ranging from discovery till registration stages.
- A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
- Coverage of the Periodontal Disease pipeline on the basis of route of administration and molecule type.
- Key discontinued pipeline projects.
- Latest news and deals relating to the products.

Reasons to buy

- Identify and understand important and diverse types of therapeutics under development for Periodontal Disease.
- Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
- Plan mergers and acquisitions effectively by identifying players of the most promising pipeline.
- Devise corrective measures for pipeline projects by understanding Periodontal Disease pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.

Table Of Contents

Periodontal Disease - Pipeline Review, H1 2013
Table of Contents

Table of Contents 2
List of Tables 4
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
Periodontal Disease Overview 7
Therapeutics Development 8
An Overview of Pipeline Products for Periodontal Disease 8
Periodontal Disease Therapeutics under Development by Companies 10
Periodontal Disease Therapeutics under Investigation by Universities/Institutes 12
Late Stage Products 13
Comparative Analysis 13
Mid Clinical Stage Products 14
Comparative Analysis 14
Early Clinical Stage Products 15
Comparative Analysis 15
Discovery and Pre-Clinical Stage Products 16
Comparative Analysis 16
Periodontal Disease Therapeutics - Products under Development by Companies 17
Periodontal Disease Therapeutics - Products under Investigation by Universities/Institutes 18
Companies Involved in Periodontal Disease Therapeutics Development 19
Aphios Corporation 19
Enzo Biochem, Inc. 20
IMAGENETIX, INC 21
Kaken Pharmaceutical Co.,Ltd. 22
CSL Limited 23
Yuhan Corporation 24
Biomedical Development Corporation. 25
Periodontal Disease - Therapeutics Assessment 26
Assessment by Monotherapy Products 26
Assessment by Route of Administration 27
Assessment by Molecule Type 29
Drug Profiles 31
POD CRC-OHS - Drug Profile 31
Product Description 31
Mechanism of Action 31
RandD Progress 31
1-Tetradecanol Complex - Drug Profile 32
Product Description 32
Mechanism of Action 32
RandD Progress 32
trafermin - Drug Profile 34
Product Description 34
Mechanism of Action 34
RandD Progress 34
Enzo-D58 - Drug Profile 36
Product Description 36
Mechanism of Action 36
RandD Progress 36
Iocide - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
Iocide - Drug Profile 38
Product Description 38
Mechanism of Action 38
RandD Progress 38
Asterias - Drug Profile 39
Product Description 39
Mechanism of Action 39
RandD Progress 39
Neisvac-C - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
C5a Receptor Antagonist - Drug Profile 41
Product Description 41
Mechanism of Action 41
RandD Progress 41
Periodontal Disease Therapeutics - Drug Profile Updates 42
Periodontal Disease Therapeutics - Dormant Products 43
Periodontal Disease - Product Development Milestones 45
Featured News and Press Releases 45
Mar 30, 2012: Kaken Pharma To Initiate Additional Phase III Trial For KCB-1D 45
Aug 12, 2009: Imagenetix Announces Publication Of Results From 1-TDC Boston University Periodontal Study In The Journal Of Periodontology 45
Jun 01, 2007: Periodontal Study On Imagenetix Compound 1-TDC Published In Journal Of Periodontology 45
Dec 11, 2006: Imagenetix Receives FDA Clearance To Begin Pre-IND Safety Studies On Anti-Inflammatory Compound 46
Jun 01, 2006: Imagenetix Announces Positive Safety Studies On Anti-Inflammatory Compound, 1-TDC 47
May 22, 2006: CombinatoRx Reports Second Positive Phase 2 Study with CRx-102 47
May 08, 2006: Imagenetix Announces 1-Tetradecanol Complex Acts To Inhibit Bacteria And Enzymes Associated With Oral Disease, Sepsis And Inflammation 47
Oct 21, 2004: Kaken Pharmaceutical Announces Results Of Early Phase II Clinical Trial On KCB-1D 48
May 29, 2002: BioMimetic Pharmaceuticals Initiates Pivotal Clinical Study with Platelet-derived Growth Factor for the Treatment of Periodontal Diseases 48
Appendix 50
Methodology 50
Coverage 50
Secondary Research 50
Primary Research 50
Expert Panel Validation 50
Contact Us 51
Disclaimer 51



List of Tables

Number of Products Under Development for Periodontal Disease, H1 2013 8
Products under Development for Periodontal Disease - Comparative Analysis, H1 2013 9
Number of Products under Development by Companies, H1 2013 11
Number of Products under Investigation by Universities/Institutes, H1 2013 12
Comparative Analysis by Late Stage Development, H1 2013 13
Comparative Analysis by Mid Clinical Stage Development, H1 2013 14
Comparative Analysis by Early Clinical Stage Development, H1 2013 15
Comparative Analysis by Discovery and Pre-Clinical Stage Development, H1 2013 16
Products under Development by Companies, H1 2013 17
Products under Investigation by Universities/Institutes, H1 2013 18
Aphios Corporation, H1 2013 19
Enzo Biochem, Inc., H1 2013 20
IMAGENETIX, INC, H1 2013 21
Kaken Pharmaceutical Co.,Ltd., H1 2013 22
CSL Limited, H1 2013 23
Yuhan Corporation, H1 2013 24
Biomedical Development Corporation., H1 2013 25
Assessment by Monotherapy Products, H1 2013 26
Assessment by Stage and Route of Administration, H1 2013 28
Assessment by Stage and Molecule Type, H1 2013 30
Periodontal Disease Therapeutics - Drug Profile Updates 42
Periodontal Disease Therapeutics - Dormant Products 43
Periodontal Disease Therapeutics - Dormant Products (Contd..1) 44



List of Figures

Number of Products under Development for Periodontal Disease, H1 2013 8
Products under Development for Periodontal Disease - Comparative Analysis, H1 2013 9
Products under Development by Companies, H1 2013 10
Products under Investigation by Universities/Institutes, H1 2013 12
Late Stage Products, H1 2013 13
Mid Clinical Stage Products, H1 2013 14
Early Clinical Stage Products, H1 2013 15
Discovery and Pre-Clinical Stage Products, H1 2013 16
Assessment by Monotherapy Products, H1 2013 26
Assessment by Route of Administration, H1 2013 27
Assessment by Stage and Route of Administration, H1 2013 28
Assessment by Molecule Type, H1 2013 29
Assessment by Stage and Molecule Type, H1 2013 30

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