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Pemphigus - Pipeline Review, H1 2015

  • February 2015
  • -
  • Global Markets Direct
  • -
  • 68 pages

Pemphigus - Pipeline Review, H1 2015

Summary

Global Markets Direct’s, ‘Pemphigus - Pipeline Review, H1 2015’, provides an overview of the Pemphigus’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Pemphigus, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Pemphigus and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Pemphigus
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Pemphigus and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Pemphigus products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Pemphigus pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Pemphigus
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Pemphigus pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Pemphigus - Pipeline Review, H1 2015
Table of Contents
Introduction 6
Global Markets Direct Report Coverage 6
Pemphigus Overview 7
Therapeutics Development 8
Pipeline Products for Pemphigus - Overview 8
Pipeline Products for Pemphigus - Comparative Analysis 9
Pemphigus - Therapeutics under Development by Companies 10
Pemphigus - Therapeutics under Investigation by Universities/Institutes 11
Pemphigus - Pipeline Products Glance 12
Late Stage Products 12
Clinical Stage Products 13
Early Stage Products 14
Unknown Stage Products 15
Pemphigus - Products under Development by Companies 16
Pemphigus - Products under Investigation by Universities/Institutes 17
Pemphigus - Companies Involved in Therapeutics Development 18
Clinuvel Pharmaceuticals Limited 18
Genmab A/S 19
HanAll Biopharma Co., Ltd. 20
Immunomedics, Inc. 21
Momenta Pharmaceuticals, Inc. 22
Novartis AG 23
PinCell srl 24
Pemphigus - Therapeutics Assessment 25
Assessment by Monotherapy Products 25
Assessment by Target 26
Assessment by Mechanism of Action 28
Assessment by Route of Administration 30
Assessment by Molecule Type 32
Drug Profiles 34
afamelanotide - Drug Profile 34
Product Description 34
Mechanism of Action 34
RandD Progress 34
Antibody for Autoimmune Disorders and Inflammation - Drug Profile 36
Product Description 36
Mechanism of Action 36
RandD Progress 36
DP-C006 - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
Drugs to Target HSP27 for Autoimmune Disorders - Drug Profile 38
Product Description 38
Mechanism of Action 38
RandD Progress 38
HL-161 - Drug Profile 39
Product Description 39
Mechanism of Action 39
RandD Progress 39
ofatumumab - Drug Profile 40
Product Description 40
Mechanism of Action 40
RandD Progress 40
PC-111 - Drug Profile 45
Product Description 45
Mechanism of Action 45
RandD Progress 45
VAY-736 - Drug Profile 46
Product Description 46
Mechanism of Action 46
RandD Progress 46
veltuzumab - Drug Profile 48
Product Description 48
Mechanism of Action 48
RandD Progress 48
Pemphigus - Recent Pipeline Updates 51
Pemphigus - Dormant Projects 60
Pemphigus - Product Development Milestones 61
Featured News and Press Releases 61
Nov 21, 2014: Immunomedics Announces Orphan Drug Designation for Veltuzumab for the Treatment of Pemphigus 61
Oct 07, 2014: Stiefel, a GSK company, announces start of phase III study of subcutaneous ofatumumab for pemphigus vulgaris 61
May 22, 2014: Scenesse receives US orphan-drug designation in Hailey-Hailey Disease 62
May 19, 2014: Afamelanotide 16mg recognised for potential to treat rare Hailey-Hailey Disease 63
Feb 10, 2014: Phase II study of SCENESSE in rare skin disorder Hailey-Hailey Disease commences 63
Oct 28, 2013: Positive pilot data published on SCENESSE in rare skin disorder 64
Jul 04, 2013: Genmab Collaborator GSK Starts New Ofatumumab Phase III Study in Rare Skin Disorder 65
Appendix 67
Methodology 67
Coverage 67
Secondary Research 67
Primary Research 67
Expert Panel Validation 67
Contact Us 67
Disclaimer 68

List of Tables

Number of Products under Development for Pemphigus, H1 2015 8
Number of Products under Development for Pemphigus - Comparative Analysis, H1 2015 9
Number of Products under Development by Companies, H1 2015 10
Number of Products under Investigation by Universities/Institutes, H1 2015 11
Comparative Analysis by Late Stage Development, H1 2015 12
Comparative Analysis by Clinical Stage Development, H1 2015 13
Comparative Analysis by Early Stage Development, H1 2015 14
Comparative Analysis by Unknown Stage Development, H1 2015 15
Products under Development by Companies, H1 2015 16
Products under Investigation by Universities/Institutes, H1 2015 17
Pemphigus - Pipeline by Clinuvel Pharmaceuticals Limited, H1 2015 18
Pemphigus - Pipeline by Genmab A/S, H1 2015 19
Pemphigus - Pipeline by HanAll Biopharma Co., Ltd., H1 2015 20
Pemphigus - Pipeline by Immunomedics, Inc., H1 2015 21
Pemphigus - Pipeline by Momenta Pharmaceuticals, Inc., H1 2015 22
Pemphigus - Pipeline by Novartis AG, H1 2015 23
Pemphigus - Pipeline by PinCell srl, H1 2015 24
Assessment by Monotherapy Products, H1 2015 25
Number of Products by Stage and Target, H1 2015 27
Number of Products by Stage and Mechanism of Action, H1 2015 29
Number of Products by Stage and Route of Administration, H1 2015 31
Number of Products by Stage and Molecule Type, H1 2015 33
Pemphigus Therapeutics - Recent Pipeline Updates, H1 2015 51
Pemphigus - Dormant Projects, H1 2015 60

List of Figures

Number of Products under Development for Pemphigus, H1 2015 8
Number of Products under Development for Pemphigus - Comparative Analysis, H1 2015 9
Number of Products under Development by Companies, H1 2015 10
Comparative Analysis by Early Stage Products, H1 2015 14
Assessment by Monotherapy Products, H1 2015 25
Number of Products by Top 10 Targets, H1 2015 26
Number of Products by Stage and Top 10 Targets, H1 2015 27
Number of Products by Top 10 Mechanism of Actions, H1 2015 28
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 29
Number of Products by Top 10 Routes of Administration, H1 2015 30
Number of Products by Stage and Top 10 Routes of Administration, H1 2015 31
Number of Products by Top 10 Molecule Types, H1 2015 32
Number of Products by Stage and Top 10 Molecule Types, H1 2015 33

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