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  4. > Transdermal Hormone Replacement: Products, Players, Markets and Forecasts

As life expectancy in the developed world increases and populations age, the incidence and associated morbidity of decreasing hormone levels have come to the forefront as a quality-of-life issue for patients and their families. For the past two decades, the healthcare industry has responded to this clinical need by developing, testing and marketing hormone replacement therapy (HRT) products. Because of their ease-of-use and dosing characteristics, drug developers are continuing to turn to transdermal delivery systems for HRT products. There are more than 40 million post-menopausal women in the United States alone, and this group is expected to grow by 50% by 2020. With the aging of the population worldwide, conditions and diseases such as menopause, osteoporosis and heart disease, which may benefit from hormone replacement therapy, are expected to become significantly more prevalent. The industry continues to attract interest in the form of new participants and products. While the global market continues to be dominated by the FDA-approved HRT products of major pharmaceutical firms, regional markets are a bit more competitive, and present unique challenges to transdermal HRT sector participants.

Highlights

· Analyzes and evaluates the global market opportunity for transdermal hormone replacement and assesses the probable impact of evolving regulatory, economic and demand factors
· Assesses transdermal products approved or in development for the delivery of therapeutic hormones
· Provides detailed descriptions of hormone replacement treatment segments, market factors, and business strategies
· Forecasts transdermal hormone replacement product demand to 2016 by geographic region and product segment
· Profiles sector companies, their product development activities, supply chain partners, business strategies, and collaboration partners

Table Of Contents

Transdermal Hormone Replacement: Products, Players, Markets and Forecasts

Summary of Contents

Executive Summary

Scope and Definitions
The Hormone Replacement Therapy Market
The Opportunity for Transdermal Hormone Replacement Therapy

The Hormone Replacement Therapy Market Opportunity

Evolution in HRT Guidelines
Regional Factors in HRT Practice
Hormone Replacement Therapy Demand Drivers 
Competitive Landscape
Factors Limiting Growth

Transdermal Drug Delivery Dynamics

Transdermal HRT Patches
Patch Designs and Construction
Transdermal Patch Manufacturing and Packaging
The Patch Manufacturing Ecosystem
Patch Economics
Transdermal HRT Gels
Transdermal Formulations
IP and Proprietary Technology
Limitations of Topical Gels and Emulsions
Transdermal HRT Sprays

Transdermal HRT Indications and Markets

Hypoestrogenism
Hypogonadism
Menopause
Vasomotor Symptoms
Vaginal Atrophy
Postmenopausal Osteoporosis

Transdermal HRT Product Assessments and Market Prospects

Approved Transdermal HRT Products
Estradiol
  Ascend 
  Azur 
  Bayer Healthcare 
  Graceway 
  KV Pharm 
  Mylan 
  Novartis
  Watson Laboratories 
  Upsher-Smith
  Faran SA 
  Janssen-Cilag
  Meda 
  Shiseido
  Solvay 
Estradiol Levonorgestrel
  Bayer Healthcare
Estradiol/Norethindrone
  Novartis 
Testosterone
  Abbott Labs 
  Auxilium 
  Endo Pharms 
  Teva 
  Watson Laboratories 
Development-Stage Transdermal HRT Products
Estrogen
Testosterone
Other Hormones

Transdermal Hormone Replacement Market Factors 

Regional Regulations 
Clinical Trials 
Quality and Reliability
Indications Prescribing Guidelines and Off-Label Prescribing
Managed Care and Payor Initiatives
Rx-to-OTC Switching

Market Forecasts

Forecast Methodology
Forecasts by Region
Forecasts by Drug Class
Forecasts by Delivery Form Factor
Market Share Data 

Market Participant Profiles

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