Outsourcing in Drug Discovery, 3rd Edition

Home >
Life Sciences >
Pharmaceutical >
Outsourcing in Drug Discovery, 3rd Edition

Report price : $ 3 500
Publication date : January 2008
Length : 160 pages

2008 has seen no decrease in the opportunities available for outsourcing drug discovery, for a number of reasons. New technologies increase the number of targets and accelerate the identification of active compounds. There is increasing pressure to develop new lead compounds due to the near-term loss of patent protection for many drug product. And there is also pressure to reduce the time spent in drug discovery and to bring drugs to market sooner, as well as the ever-present cost considerations.

Kalorama Information's Outsourcing in Drug Discovery offers unparalleled discussion of the drug discovery outsourcing market. It presents viewpoints from both customers and suppliers. Segments, size, and growth of the market are presented. The trend toward the increased use of offshore suppliers is covered in detail. The report also provides profiles of 23 suppliers, representative of those active in this market.

Segments covered in this report include:

Chemistry Services
- Building Blocks
- Compound Synthesis
- Libraries
- Process Research
- Other Services
Biology Services
- Protein Expression
- Structural Analysis
- Target Validation
- Pathways Analysis
- Other Services
Screening Services
- Assay Development
- Primary Screening
- Secondary Screening
Lead Optimization
- Early ADMET
- Analogues Creation
- Computational Support
- Other services

In addition to market data and forecasts, the report covers issues such as:

What factors should a client consider when deciding whether to do a project in-house or outsource it?
Is it in the client's best interest to seek a domestic outsourcing partner, or go with an overseas supplier?
How does the client select the CRO that is best for him?
What are the best practices when working with a CRO?
How do you measure his effectiveness?
How do you avoid problems with your CRO?
How do you maximize benefits?

This report looks offshore at outsourcing suppliers based in three major areas: India, China, and Eastern Europe. The relative advantages each country provides are contrasted with some of their limitations. The report asses which projects are moving to which suppliers and why.

TABLE OF CONTENTS

CHAPTER ONE: EXECUTIVE SUMMARY

Overview
Scope and Methodology
Introduction
- Pharmaceutical industry challenges
The Drug Discovery Process and Outsourcing
- Accelerating the Drug Discovery Process
- Bottlenecks in the Drug Discovery Process
- Outsourcing to Increase Efficiency
The Outsourcing Decision
- Developing an Outsourcing Plan
- Contract Research Organization
- Strategic Versus Tactical Outsourcing Model
- Effective Communication Is Essentia
- Mitigating the Challenges of Protecting IP Rights
Offshoring Contract Drug Discovery
- Factors to Consider in Offshore Outsourcing
- Benefits of Global Outsourcing
- Cost Advantage
- Concerns about Global Outsourcing
- Outsourcing to China
- WuXi China’s Largest CRO
- First Chinese CRO Alliance
- FDA to Establish Office at US Embassay in China
- China's Handling of IP Rights and Laws
- Outsourcing to India
- India’s Handling of IP Rights and Laws
- Outsourcing to Eastern Europe
Drug Discovery Outsourcing Market
- Current Market and Forecast Summary

CHAPTER TWO: INTRODUCTION

Overview
- Number of NME Filings in Decline While R&D Spending Rising
- Ramping Up the Pipelines
Outsourcing Drug Discovery
The Outsourcing Decision
- Decision Criteria
- Factors to Consider in Offshore Outsourcing
- Benefits of Global Outsourcing
  - Cost Advantage
  - Access to Talent and Technologies
  - Compressed Timelines
  - Increased Production
- Concerns About Global Outsourcing
  - Intellectual Property Protection (IP)
  - Confidential Information and Trade Secrets
  - Fraud and Corruption
  - Meeting Regulatory Compliance Demands
  - Long Distance
Selecting a Contract Research Organization
- Choosing the Right CRO
  - Experience is Paramount
  - Facility Standards
  - Excellent Track Record
- Global Outsourcing

CHAPTER THREE: THE DRUG DISCOVERY PROCESS

Introduction—Discovery Stages
- Target Identification
- Target Validation
- High Throughput Screening
- Lead Optimization
Accelerating the Drug Discovery Process
Technologies Used in Drug Discovery
- Combinatorial Chemistry
- Bioinformatics/Pharmacogenomics
- ADME/Tox Screening
- High Throughput Screening
- Computational Modeling and Bioinformatics
Addressing Bottlenecks in the Drug Discovery Process
Outsourcing to Increase Efficiency
- Outsourcing to Access Novel Technologies
- Bioinformatics
- Lab-on-a-Chip: Microfluidics in Drug Discovery

CHAPTER FOUR: OUTSOURCING DRUG DISCOVERY

Overview
Contract Research Organizations
- Introduction
- Role of a CRO
- Strategic Versus Tactical Outsourcing Model
- The Tactical Model
- The Strategic Model
- Effective Communication is Essential for a Successful Partnership
- Mitigating the Challenges of Protecting IP Rights
Offshoring Contract Drug Discovery
- Introduction
- Center of Gravity for the Pharmaceutical Industry Shifting from West to East
- Evolution of Contract Drug Discovery in Asia
Outsourcing to China
- Introduction
- Multi-National Pharmaceutical Companies Establish Drug Discovery Facilities in China
- Chinese Contract Research Organizations
  - WuXi China’s Largest CRO
  - First Chinese CRO Alliance
- FDA to Establish Office at US Embassay in China
- China's Handling of IP Rights and Laws
- IP Rights Enforcement System
Outsourcing to India
- Introduction
- AstraZeneca Sets up Drug Discovery Facility in Bangalore
- Drug Discovery Services in India
- India’s Handling of IP Rights and Laws
  - Patent Filing Considerations
  - Limitations on Patentability
  - Compulsory Licenses
Outsourcing to Eastern Europe
- Introduction
- Russian and Ukraine CROs

CHAPTER FIVE: DRUG DISCOVERY OUTSOURCING MARKET

Overview
Current Market Size and Forecast
Contract Drug Discovery Competitors
- Acquisitions to Gain Market Share or Entrance to the Market
Market Analysis by Segment
- Chemistry Services Market and Forecast
- Biology Services Market
- High Throughput Screening Services Market
- Lead Optimization Services Market
- Current Market and Forecast
Market Growth Expanding Global Reach of Drug Discovery Services

CHAPTER SIX: COMPETITOR PROFILES

Albany Molecular Research, Inc.
- History and Lines of Business
- Drug Discovery Services
- Financial Information
Asinex Ltd.
- History and Lines of Business
- Drug Discovery Services
BioDuro, Inc.
- History and Lines of Business
- Drug Discovery Services
  - Chemistry Services
  - Biology Services
- Bridge Laboratories
  - History and Lines of Business
  - Drug Discovery Services
- Services in U.S.
- Services in China
- Financial Information
Caliper Life Sciences
- History and Lines of Business
- Drug Discovery Services
- Financial Information
Charles River Laboratories, Inc.
- History and Lines of Business
- Drug Discovery Services
- Financial Information
Chembiotek Research
- History and Lines of Business
- Drug Development Services
ChemBridge Research Laboratories, Inc.
- History and Lines of Business
- Drug Discovery Services
Chemical Diversity Inc.
- History and Lines of Business
  - Drug Discovery Services
  - Lead Optimization Services
  - High Throughput Services
  - Biologically Annotated Libraries
  - Focused Diversity
deCODE Chemistry and Biostructures
- History and Lines of Business
- Drug Discovery Services
  - Structural Biology Services
  - High Throughput Screening & Assay Services
  - Lead Optimization
  - Financial Information
Enamine Ltd.
- History and Lines of Business
- Drug Discovery Services
  - Screening Compounds
  - Screening Compounds From REAL Database®
  - Lead Optimization
  - Discovery Chemistry and Custom Synthesis
  - Research
Evotec OAI
- History and Lines of Business
- Drug Discovery Services
  - Assay Development Services
  - High throughput Screening
  - Medicinal Chemistry Services
  - Compound Library Services
- Financial Information
GVK Biosciences Private Limited
- History and Lines of Business
- Drug Discovery Services
  - Bioinformatics
  - Chemoinformatics
  - Structural Biology
  - Biology Services
Hutchison MediPharma Ltd.
- History and Lines of Business
- Drug Discovery Services
  - Discovery Chemistry
  - Discovery Biology
  - Discovery Pharmacology
  - Drug Metabolism and Pharmacokinetics (DMPK)
J-Star Research, Inc.
- History and Lines of Business
- Drug Discovery Services
Jubilant Biosys Ltd.
- History and Lines of Business
- Drug Discovery Services
- Discovery Informatics
- Discovery Research
- Drug Development
- IT Services
MDS Pharma Services
- History and Lines of Business
- Drug Discovery Services
- Financial Information
Medicilon Inc.
- History and Lines of Business
- Drug Discovery Services
  - Custom Chemical Synthesis
  - Pharmacokinetics
  - Metabolism Services
  - Bioanalytical Services
  - Structural Biology Services
  - Other Biological Services
Pharmacopeia Drug Discovery, Inc.
- History and Lines of Business
- Drug Discovery Services
  - Lead Optimization
  - ADME and Toxicity Characteristics of New Molecules
  - In vivo Optimization
  - Early ADME/Tox Determination
- Financial Information
Ricerca Biosciences, LLC
- History and Lines of Business
- Drug Discovery Services
- Financial Information
Scynexis, Inc.
- History and Lines Business
- Drug Discovery Services
  - Medicinal Chemistry
  - Custom Synthesis
  - High Throughput Purification & Analysis
  - ADMET & Bioanalytical Services
  - Bioanalytical Capabilities
  - Data Management And Collaboration
Shanghai ChemPartner Co.,Ltd.
- History and Lines of Business
- Drug Discovery Services
- Discovery Chemistry
- Library Generation
- Analytical Chemistry
- Medicinal Chemistry
- ADME Studies
- Natural Product Chemistry
- Computational Chemistry and Drug Design
WuXI PharmaTech Co. Ltd.
- History and Lines of Buisness
- Drug Discovery Services
- Discovery Chemistry Services
- Analytical Services
- Biological Services
- Financial Information

APPENDIX: COMPANY DIRECTORY

TABLE OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Exhibit 1-1: Drug Discovery Timeline: Research to Viable Product to Commercialization
Exhibit 1-2: NMEs and New BLAs Filed, 1996-2007
Exhibit 1-3: Global R&D Spending, 1996-2007
Exhibit 1-4: Global Drug Discovery Outsourcing Market 2005-2013
Exhibit 1-5: Share of Outsourced Drug Discovery Market by Segment (Biology Services, Chemistry Services, Lead Optimization, High Throughput Screening) 2007

CHAPTER TWO: INTRODUCTION

Exhibit 2-1: Number of NMEs and New BLAs Filed 1996-2007
Exhibit 2-2: Global R&D Spending 1996-2007
Exhibit 2-3: Factors Involved in Making Outsourcing Decisions

CHAPTER THREE: THE DRUG DISCOVERY PROCESS

Exhibit 3-1: The Drug Discovery Process
Exhibit 3-2: Drug Discovery Timeline: Research to Viable Product to Commercialization
Exhibit 3-3: Bioinformatics/Pharmacogenomics: The Role of the “-Omics”
Exhibit 3-4: Causes of New Drug Attrition
Exhibit 3-5: Drug Discovery Processes Frequently Outsourced
Exhibit 3-6: Bioinformatics as a Central Hub A Schematic of Discovery Disciplines and Methods

CHAPTER FOUR: OUTSOURCING DRUG DISCOVERY

Exhibit 4-1: Major Chinese Drug Discovery CROs (Company, Location, Services)
Exhibit 4-2: Major Indian Drug Discovery CROs (Company, Location, Services)
Exhibit 4-3: Major CROs Operating in Russia and the Ukraine

CHAPTER FIVE: DRUG DISCOVERY OUTSOURCING MARKET

Exhibit 5-1: Global Drug Discovery Outsourcing Market 2005-2013
Exhibit 5-2: Contract Drug Discovery Services by Market Segment (Chemistry, Biology, High-Throughput Screening, Lead Optimization) 2005-2013
Exhibit 5-3: Leading Contractors by Market Segment
Exhibit 5-4: Major Acquisitions in Drug Discovery Outsourcing
Exhibit 5-5: Market Share of the Segments within the Drug Discovery Market 2007
Exhibit 5-6: Chemistry Services Market: Revenues, Annual Growth, and Share of the Outsourced Drug Discovery Market 2005-2013
Exhibit 5-7: Chemistry Market Revenue by Service Type (Building Blocks Compound Synthesis, Libraries, Process Research, Other Services) 2007
Exhibit 5-8: Biology Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market 2005-2013
Exhibit 5-9: Biology Market Revenue by Service Type (Protein Expression, Structural Analysis, Target Validation, Pathways Analysis, Other Service) 2007
Exhibit 5-10: Screening Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market 2005-2013
Exhibit 5-11: Screening Services Market Revenue by Service Type (Assay Development, Primary Screening, Secondary Screening) 2007
Exhibit 5-12: Lead Optimization Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market 2005-2013
Exhibit 5-13: Lead Optimization Services Market by Service Type (Early ADME/Tox, Create Analogues,Computational Support, and Other Services) 2007
Exhibit 5-14: Global Expansion of Drug Discovery Services: A Selection of Companies Expanding East and West

RELATED REPORTS

Cancer Therapeutics Markets

$ 3 400
May 2008
160 pages

Cancer is the second leading cause of death by disease in the United States, exceeded only by heart disease. Traditionally cancer has been treated with surgery, chemotherapy, hormones and radiation therapy, alone or in combination. Emerging technologies include photodynamic therapy, gene therapy, bi ...

Industries : Pharmaceutical | Countries : USA, Japan, United Kingdom

World Wound Care Markets 2008

$ 3 300
January 2008
250 pages

2008 has seen no decrease in attention on wound care products. The aging of the population and a constant demand for products that speed healing and improve outcomes drives the wound care industry. For market watchers, this makes for a dynamic market that has changed in recent years with biological ...

Industries : Pharmaceutical | Countries : Canada, USA, Japan

The Antibacterial Drug Market Analysis 2008-2013

$ 2 501
March 2008
250 pages

This brand new market analysis by visiongain examines the prospects for antibacterial drugs from 2008-2013, including sales forecasts for leading pharmaceutical products. The antibacterial market is large in terms of disease area as well as the different drug classes used to treat these infections. ...

Industries : Pharmaceutical | Countries : USA

Sleep Disorders Market Analysis 2008-2018

$ 2 501
March 2008
250 pages

More than 80 sleep disorders have been identified. They affect over 200 million people worldwide. The report focuses on the market for following sleep disorders: Insomnia Restless legs syndrome (RLS) Narcolepsy and Obstructive Sleep Apnoea / Hypopnea Syndrome (OSAHS) The market penetration for insom ...

Industries : Pharmaceutical | Countries : USA, Japan, Germany, Spain, France, Italy, United Kingdom

Live-Licensing and In-life testing: R and D Processes and Regulation for New Drugs, 2008-2020

$ 2 501
January 2008
250 pages

Visiongain predict that the current phase I to IV clinical testing process will eventually be selectively or wholly replaced by a system known as “in-life” testing or “live” licensing. Those proposals involve cumulative testing of the drug throughout its lifecycle. The industry would continu ...

Industries : Pharmaceutical | Countries : USA, Japan, Germany, United Kingdom

Company Study of Huadong Medicine

$ 599
May 2008
33 pages

Huadong Medicine Co., Ltd. was founded in March, 1993, based on the medicine distribution network in Hanzhou, capital of Zhejiang province, after a government-oriented restructuring. On December 22, 1999, the company went public on the Shenzhen Stock Exchange and raised around CNY288 million through ...

Industries : Pharmaceutical | Countries : China, USA

The Emerging Role of Postmarketing Clinical Research: Regulatory issues, strategic drivers and overall trends

$ 3 835
May 2008
121 pages

Post-marketing studies are undertaken to delineate additional clinical information concerning a drug’s risks, benefits, and optimal use. Industry stakeholders acknowledge that research undertaken in order to obtain marketing authorization (MA) does not always coincide with initiatives to ensure th ...

Industries : Pharmaceutical | Countries : USA

Drug Repositioning Strategies - Serendipity by design

$ 3 800
May 2008
93 pages

IntroductionDrug repositioning has several advantages over traditional discovery-reduced cost, risk and time to market-compared with traditional discovery, providing an attractive prospect for Big Pharma, scrambling to fill pipelines in an increasingly harsh market environment. As competition to inl ...

Industries : Pharmaceutical | Countries : USA

Forecast Insight: Osteoarthritis - The COX-2 pipeline collapses - Provides analysis of recent events in the osteoarthritis disease area and their impact on the market. Includes an event-based, indication-specific ten year forecast of both pipeline and mar

$ 15 200
May 2008
71 pages

IntroductionWith several recent non-approvable decisions in the osteoarthritis market since 2006, Datamonitor has updated its forecast to account for the effect on the market. We have revised the market outlook over the next 10 years using the latest IMS data. We expect the market to grow steadily, ...

Industries : Pharmaceutical | Countries : Mexico, Brazil, Canada, USA, Japan, Croatia, Germany, Spain, France, Italy, United Kingdom, Australia

Stakeholder Opinions: Percutaneous Coronary Intervention - Adverse events with drug-eluting stents demand a new safety standard

$ 3 800
April 2008
95 pages

IntroductionWhile drug eluting stents have been successful in reducing the rate of restenosis following percutaneous coronary intervention, there have been safety scares over a new problem: “in-stent thrombosis”. Opinion leaders are divided over the gravity of this problem, but positive safety d ...

Industries : Pharmaceutical | Countries : USA, Croatia

Outsourcing in Drug Discovery, 3rd Edition - get our PDF brochure

24/7 Customer Service

Contact Clare now !

(866) 682 9815
Ask Clare by email

Related industries

Pharmaceutical Industry
- in USA
- in China
- in India
- in Russia
- in Ukraine

Related countries

ReportLinker is a professional search engine that provides an easy access to 1,2 million market research reports and industry statistics published by 200,000 authoritative sources.