World Biocompatible Materials Market

World Biocompatible Materials Market

This report analyzes the worldwide markets for Biocompatible Materials in Millions of US$. The specific product segments analyzed are Polymeric Materials, Metallic Materials, Natural Materials, and Other Materials. The report provides separate comprehensive analytics for the North America, Japan, Europe, and Rest of World. Annual forecasts are provided for each region and product segment for the period of 2000 through 2015. The report profiles 70 companies including many key and niche players worldwide such as A.P. Pharma, Inc., AST Products, Inc., Angiotech Pharmaceuticals Inc., Artimplant, AST Products, Inc., Biocoat, Inc., BIOSYNTECH, DENTSPLY International Inc., Invibio, Integra LifeSciences Holdings Corporation, Orthovita, SaluMedica, LLC, SurModics, Synthes Inc, and United States Surgical. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

BIOCOMPATIBLE MATERIALS MCP-1094
A GLOBAL STRATEGIC BUSINESS REPORT


CONTENTS


I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-2
Product Definition and Scope of Study I-3
Polymeric Materials I-3
Metallic Materials I-3
Natural Materials I-3
Other Materials I-3

II. EXECUTIVE SUMMARY

1. Industry Overview II-1
R&D Creating Brighter Avenues II-1
Current and Future Analysis II-1
Regional Perspective II-1
Segment Wise Perspective II-1
Factors Determining Market Growth II-1
Awareness of Basic Mechanisms of Cell-Material Interaction II-1
Birth of Cross-Disciplinary Field of Tissue Engineering II-2
Rise in Biomaterial Prices II-2
Stem-Cell Technology - A Threat II-2

2. Product Overview II-3
Biocompatible Materials - An Introduction II-3
Definition of Biocompatible Materials II-3
Applications II-3
Orthopedic Applications II-3
Cardiovascular Applications II-3
Dental Applications II-4
Biomaterials as Skin Replacements II-4
Biomaterials as Scaffolds for Tissue Engineering II-4
Product Segments II-4
Polymeric Materials II-4
Hydrogels II-5
Biodegradable Polymers II-5
Metallic Materials II-5
Natural Materials II-7
Collagen II-7
Hyaluronic Acid II-7
Other Materials II-7
Ceramics II-7
Bioactive Ceramics II-8
Applications II-8
Bone Substitutes II-8
Articulating Surfaces in Joint Implants II-8
Composites II-8
Pyloritic Carbon II-8
Biomaterial Segments and Applications: An Outline II-9

3. Product Trends II-10
Biomaterials Play Crucial Role in Implants Market II-10
Natural Substances find Increasing Application in Biomaterial
Syntheses II-10
Plastic Companies Join the Fray as Manufacturers of
Biodegradable Materials II-10
Ceramic Fillings as Substitute for Silver-Tin-Mercury Amalgam
Fillings II-11
Ceramics Offer Significant Potential in Crown Syntheses II-11
Hafnium - A Promising Material for Biocompatible Coatings II-11
Chitin as a New Biomaterial II-11
Bioglass - A Potential Material for Bone Regeneration II-11
Collagen - An Efficient Biomaterial for Synthetic Vascular Grafts II-12
Biopolymers as Biomaterials II-12
Bioabsorbable Intelligent Materials II-12
Biocompatible Coatings - A Boon for Medical Implant Applications II-12
Nanotechnology - Revolutionizes Development of Biomaterial
Implants II-12

4. End-Use Market Analysis II-13
Biosensors II-13
Implants II-13
Common Orthopedic Implants: Merits and Demerits II-13
Biocompatibility of Material Implants with Blood II-14
Integrating Heparin to Polymeric Surface II-14
Dental Implants II-15
Crown and Bridge Consumption II-15
Table 1: Worldwide Dental Implant Market (2005): Percentage
Share Breakdown for Nobel Biocare, Straumann, Biomet/3i,
Zimmer Dental, Dentsply/ Friadent and Others (includes
corresponding Graph/Chart) II-15
Joint Implant II-15
Artificial Organs II-15
Artificial Heart II-15
Totally Implantable Artificial Heart (TAH) System II-15
Pneumatic Total Artificial Heart (PTAH) II-15
Cardiopulmonary Bypass System for Long-term Use II-16
Ventricular Assist Device II-16
Artificial Blood Vessels II-16
Artificial Blood II-16
Artificial Skin II-16
Surface Coatings II-17
Materials for Drug Delivery Systems II-17
Polyethylene Glycol as a Drug Delivery System II-17
Hydrogels as Drug Delivery System II-17
Vinylic based Drug Delivery Systems II-17
Collagen Based Drug Delivery System II-17
Electrodes II-18
Tissue Replacement Materials II-18
Dialysis/Separation/Filtration Systems II-18
Dialysis II-18
Filtration and Separation II-19
Cosmetic and Dental Materials II-19
Biomaterials for Cosmetic Formulations II-19

5. Research and Development II-20
Biocompatible Materials - Key Research Objectives II-20
R&D Activity II-21
French Inventors Develop Three-Dimensional Filet Stitch
Fabric Wall Reinforcement II-21
California Inventor Develops Biocompatible Material II-21
Scientists Develop Process for Producing Biocompatible Fibers II-21
Penn State Researchers Develop New Niobium Molding Process II-21
Doxa Commences Clinical Trials for Novel Biomaterial II-21
FzioMed Concludes Preliminary Study for Oxiplex Gel II-21
MIV’s Biomaterial Stent Coating Clears Pyrogen Clinical Testing II-22

6. Regulatory Environment II-23
FDA Regulations II-23
American Society for Testing and Materials (ASTM) II-23
Joint Research Center (JRC) II-23
Biocompatibility Testing of Materials II-23
Testing Levels II-23
General Biocompatibility Testing II-23
Individual Biocompatibility Testing II-24
Testing Methods II-24

7. Product Introductions/Innovations II-25
Invibio® Launches ENDOLIGN™ Polymer Composite II-25
Zimmer Dental Launches the Puros® Dermis Allograft Tissue Matrix II-25
Integra Launches Nerve Injury Products II-25
DePuy Mitek Expands Orthopedics Product Portfolio II-26
DSM Dyneema Introduces Polyethylene Fiber II-26

8. Recent Industry Activity II-27
Tyco International Acquires Confluent Surgical II-27
SurModics Acquires Intralytix’s Biodegradable Polymer Technology II-27
Orthovita Signs a Collaboration Agreement with Aastrom
Biosciences for Orthopedic Products II-27
Kuhnil Pharma Acquires Rights from BioSyntech II-27
SurModics Licenses Hydrophilic Coating to Devax II-27
BioSyntech Receives Notice of Allowance from the US Patent and
Trademark Office for BST-CarGel® II-28
Artimplant Signs License and Development Agreements with Small
Bone Innovations II-28
SaluMedica Licenses Proprietary Biomaterial to Spine Medica II-28
SurModics Licenses Hydrophilic Technology to Medtronic II-28
SurModics Obtains Exclusive Rights from Rutgers University to
Biodegradable Polymers for Ophthalmology II-28
MIV Therapeutics Inks Research Agreement with University of
British Columbia II-29
Zimmer Acquires Implex II-29
Biomet Acquires Interpore II-29
Angiotech Acquires NeuColl II-29
Synthes-Stratec Inc. and Mathys Medizinaltechnik AG Merge II-29
Kyocera and Kobe Steel Forms a Joint Venture II-30
Angiotech Expands Biomaterial Licensing Agreement with Poly-Med II-30
Genzyme Corp Enters into Agreement with Wyeth Pharmaceuticals II-30
OctoPlus Grants License to SurModics to Acquire Two Novel
Biodegradable Polymers II-30
GP Surgical Receives FDA Approval for TiMESH II-31

9. Focus on Select Players II-32
A.P. Pharma, Inc. (USA) II-32
Angiotech Pharmaceuticals Inc. (Canada) II-32
Artimplant (Sweden) II-32
AST Products, Inc. (USA) II-33
Biocoat, Inc. (USA) II-33
BIOSYNTECH (Canada) II-33
DENTSPLY International Inc. (USA) II-33
Invibio (UK) II-34
Integra LifeSciences Holdings Corporation (USA) II-34
Orthovita (USA) II-35
SaluMedica, LLC (USA) II-35
SurModics (USA) II-35
Synthes Inc (USA) II-36
United States Surgical (USA) II-36

10. Global Market Perspective II-37
Table 2: World Recent Past, Current and Future Analysis for
Biocompatible Materials by Geographic Region - North America,
Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2000 through 2010 (includes corresponding Graph/Chart) II-37

Table 3: World Long-term Projections for Biocompatible
Materials by Geographic Region -North America, Japan, Europe
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2011 through 2015
(includes corresponding Graph/Chart) II-38

Table 4: World 10-Year Perspective for Biocompatible Materials
by Geographic Region - Percentage Breakdown of Dollar Sales
for North America, Japan, Europe, and Rest of World Markets
for Years 2003, 2008 and 2012 (includes corresponding
Graph/Chart) II-39

Table 5: World Recent Past, Current and Future Analysis for
Polymeric Materials by Geographic Region - North America,
Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2000 through 2010 (includes corresponding Graph/Chart) II-40

Table 6: World Long-term Projections for Polymeric Materials
by Geographic Region -North America, Japan, Europe and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2011 through 2015 (includes
corresponding Graph/Chart) II-41

Table 7: World 10-Year Perspective for Polymeric Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
North America, Japan, Europe, and Rest of World Markets for
Years 2003, 2008 and 2012 (includes corresponding Graph/Chart) II-42

Table 8: World Recent Past, Current and Future Analysis for
Metallic Materials by Geographic Region - North America,
Japan, Europe, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2000 through 2010 (includes corresponding Graph/Chart) II-43

Table 9: World Long-term Projections for Metallic Materials by
Geographic Region -North America, Japan, Europe and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2011 through 2015 (includes
corresponding Graph/Chart) II-44

Table 10: World 10-Year Perspective for Metallic Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
North America, Japan, Europe, and Rest of World Markets for
Years 2003, 2008 and 2012 (includes corresponding Graph/Chart) II-45

Table 11: World Recent Past, Current and Future Analysis for
Natural Materials by Geographic Region - North America, Japan,
Europe, and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-46

Table 12: World Long-term Projections for Natural Materials by
Geographic Region -North America, Japan, Europe and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2011 through 2015 (includes
corresponding Graph/Chart) II-47

Table 13: World 10-Year Perspective for Natural Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
North America, Japan, Europe, and Rest of World Markets for
Years 2003, 2008 and 2012 (includes corresponding Graph/Chart) II-48

Table 14: World Recent Past, Current and Future Analysis for
Other Materials by Geographic Region - North America, Japan,
Europe, and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) II-49

Table 15: World Long-term Projections for Other Materials by
Geographic Region -North America, Japan, Europe and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2011 through 2015 (includes
corresponding Graph/Chart) II-50

Table 16: World 10-Year Perspective for Other Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
North America, Japan, Europe, and Rest of World Markets for
Years 2003, 2008 and 2012(includes corresponding Graph/Chart) II-51

III. MARKET

1. North America III-1
A.Market Analysis III-1
Outlook III-1
Regulatory Environment III-1
FDA Regulations III-1
American Society for Testing and Materials (ASTM) III-2
R&D Activity III-2
Potential Biomaterial Shortage III-3
Effects of Potential Shortages III-3
Product Introductions/ Innovations III-4
Strategic Corporate Developments III-4
Select Players III-8
B.Market Analytics III-12
Table 17: North America Recent Past, Current and Future
Analysis for Biocompatible Materials by Product Segment -
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) III-12

Table 18: North America Long-term Projections for
Biocompatible Materials by Product Segment - Polymeric
Materials, Metallic Materials, Natural Materials & Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2011 through 2015 (includes
corresponding Graph/Chart) III-13

Table 19: North America 10-Year Perspective for
Biocompatible Materials by Product Segment - Percentage
Breakdown of Dollar Sales for Polymeric Materials, Metallic
Materials, Natural Materials and Other Materials Markets for
2003, 2008 and 2012 (includes corresponding Graph/Chart) III-13

2. Japan III-14
A.Market Analysis III-14
Outlook III-14
An Overview III-14
Import Scenario: Implants III-14
Table 20: Japanese Percentage Imports by Implant Type
(includes corresponding Graph/Chart) III-15
History III-15
Major Biomaterial Research Groups III-15
Institute of Biomedical Engineering (Tokyo Women’s Medical
University) III-15
Tissue Engineering Research Institute (Kyoto University) III-15
Institute of Biomaterials and Bioengineering (Tokyo Medical
and Dental University) III-15
Principal Research Institutions III-16
Regulatory Environment III-16
Medical Affairs Law III-16
Strategic Corporate Development III-16
B.Market Analytics III-17
Table 21: Japanese Recent Past, Current and Future Analysis
for Biocompatible Materials by Product Segment - Polymeric
Materials, Metallic Materials, Natural Materials and Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-17

Table 22: Japanese Long-term Projections for Biocompatible
Materials by Product Segment - Polymeric Materials, Metallic
Materials, Natural Materials & Other Materials Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2011 through 2015 (includes corresponding
Graph/Chart) III-18

Table 23: Japanese 10-Year Perspective for Biocompatible
Materials by Product Segment - Percentage Breakdown of
Dollar Sales for Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets for 2003, 2008
and 2012 (includes corresponding Graph/Chart) III-18

3. Europe III-19
A.Market Analysis III-19
Outlook III-19
UK Bioceramic Market III-19
Regulatory Environment III-19
Government Regulations III-19
Joint Research Center (JRC) III-19
Product Introductions/Innovations III-20
Strategic Corporate Developments III-20
Review of Select Players III-21
B.Market Analytics III-22
Table 24: European Recent Past, Current and Future Analysis
for Biocompatible Materials by Product Segment - Polymeric
Materials, Metallic Materials, Natural Materials and Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2000 through 2010 (includes
corresponding Graph/Chart) III-22

Table 25: European Long-term Projections for Biocompatible
Materials by Product Segment - Polymeric Materials, Metallic
Materials, Natural Materials & Other Materials Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2011 through 2015 (includes corresponding
Graph/Chart) III-23

Table 26: European 10-Year Perspective for Biocompatible
Materials by Product Segment - Percentage Breakdown of
Dollar Sales for Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets for Years
2003, 2008 and 2012 (includes corresponding Graph/Chart) III-23

4. Rest of World III-24
A.Market Analysis III-24
Outlook III-24
Strategic Corporate Development III-24
B.Market Analytics III-24
Table 27: Rest of World Recent Past, Current and Future
Analysis for Biocompatible Materials by Product Segment -
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2000 through
2010 (includes corresponding Graph/Chart) III-24

Table 28: Rest of World Long-term Projections for
Biocompatible Materials by Product Segment - Polymeric
Materials, Metallic Materials, Natural Materials & Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2011 through 2015 (includes
corresponding Graph/Chart) III-25

Table 29: Rest of World 10-Year Perspective for
Biocompatible Materials by Product Segment - Percentage
Breakdown of Dollar Sales for Polymeric Materials, Metallic
Materials, Natural Materials and Other Materials Markets for
2003, 2008 and 2012 (includes corresponding Graph/Chart) III-25

IV. COMPETITIVE LANDSCAPE