Global Biocompatible Materials Industry

  • July 2014
  • -
  • Global Industry Analysts
  • -
  • 204 pages

This report analyzes the worldwide markets for Biocompatible Materials in US$ Million by the following Product Segments: Polymeric Materials, Metallic Materials, Natural Materials, and Other Materials. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Rest of World. Annual estimates and forecasts are provided for the period 2013 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 59 companies including many key and niche players such as -

AdvanSource Biomaterials Corporation
BASF Corporation
Berkeley Advanced Biomaterials, Inc.
Biomet, Inc.
BioMimetic Therapeutics LLC

Table Of Contents




I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation and Reporting Level I-2
Quantitative Techniques and Analytics I-3
Product Definition and Scope of Study I-3
Polymeric Materials I-3
Metallic Materials I-4
Natural Materials I-4
Other Materials I-4


II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW II-1
Biocompatible Materials - Transforming Medicine II-1
Current and Future Analysis II-2
Key Growth Drivers II-2
Increasing Rand D Investments - The Growth Impetus II-2
Assessment of Worldwide RandD Activities in the Area of
Biomaterials II-3
Technological Advancements Foster Growth for Biomaterials II-3
Rising Prevalence of Arthritis and Other Orthopedic Disorders
Drives Biomaterials Market II-4
Developing Regions to Propel Future Growth II-4
Ageing Population - A Perennial Growth Driver II-5
Table 1: Elderly Population (60+ Years) as a Percentage of
the Total Population (2012 and 2050) (includes corresponding
Graph/Chart) II-5

Table 2: Global Aging Population by Age Group: 1975-2050
(includes corresponding Graph/Chart) II-6
Factors Determining Market Growth II-6
Awareness of Basic Mechanisms of Cell-Material Interaction II-6
Birth of Cross-Disciplinary Field of Tissue Engineering II-6
Rise in Biomaterial Prices II-7
Reimbursement Issues Haunt Biomaterial Market II-7

2. MARKET TRENDS and ISSUES II-8
Entering the Era of Self-Healing - Next Generation of
Biomaterials II-8
Tissue Engineering and Regenerative Medicine - The Next Growth
Avenues II-8
Scaffolds for Tissue Engineering II-9
Nanotechnology - Revolutionizing Development of Biomaterial
Implants II-10
Increasing Adoption of Medical Implants Fuels Demand II-11
Table 3: Select Musculoskeletal Conditions - Percentage
Breakdown by Age Group (includes corresponding Graph/Chart) II-11

Table 4: Global Knee and Hip Implants Market (2013):
Percentage Share Breakdown of Revenues by Category (includes
corresponding Graph/Chart) II-12
Bone Graft Procedures - Market Opportunity II-12
Growing Use of Dental Biomaterials Aiding Market Growth II-12
Natural Substances find Increasing Application in Biomaterial
Syntheses II-13
Biocompatible Coatings Playing an Indispensable Role II-13
Active Coatings to Grow in Demand II-14
Major Applications of Hemocompatible Coatings II-14
Age of Bioabsorbable Stents II-15
Wound Care Biologics Gain Prominence with Biomaterial Products II-15
Advanced Ceramics Gain Preeminence in Regenerative Medicine Field II-16
Orthobiologics Gain Traction in the Bone Grafts Market II-16
Table 5: Global Orthobiologics Market (2012): Percentage
Breakdown of Value Sales for Allograft and DBM, Blood and
Marrow-based Products, Growth Factors, Hemostasis, Synthetic
Bone Graft Substitutes and Viscosupplements (includes
corresponding Graph/Chart) II-17

Table 6: Leading Players in the Global Orthobiologics Market
(2013): Percentage Breakdown of Value Sales for Baxter,
JandJ/Synthes, Medtronic, Sanofi, Stryker and Others (includes
corresponding Graph/Chart) II-18
Future Directions - Insight into Select Areas of Research II-18
Use of Photopolymerizable Polymers II-18
Electrically Conductive Polymers II-18
Protein-based Biomaterials II-18
Advanced Hydrogels II-19
Biodegradable Scaffolds II-19
Immuno-modulatory Biomaterials II-19
Collagen - An Efficient Biomaterial for Synthetic Vascular Grafts II-20
Chitin as a New Biomaterial II-20

3. PRODUCT OVERVIEW II-21
Biocompatible Materials - An Introduction II-21
Changing Definition of Biomaterials II-21
Definition of biocompatibility- Then and Now II-21
Evolution of Biocompatible Material Science II-22
Important Milestones in Biomaterials Evolution II-22
Product Segments II-23
Polymeric Materials II-23
Hydrogels II-23
Biodegradable Polymers II-23
Metallic Materials II-24
Natural Materials II-25
Collagen II-25
Hyaluronic Acid II-25
Other Materials II-25
Ceramics II-25
Bioactive Ceramics II-26
Composites II-26
Pyrolitic Carbon II-26
List of Technological Issues of Natural Biomaterials II-27
List of Few Technological Issues of Other Biomaterial
Categories II-27
Applications of Biocompatible Materials II-28
Biomaterials Categories and their Applications II-28
List of Biomaterial Applications with respect to Medical Problem II-28
Biomaterial Applications with respect to Organ II-28
Biomaterial Applications with respect to Body Systems II-29
Biomaterial Segments and Applications: An Outline II-29

4. THERAPEUTIC AREAS - OPPORTUNITIES AND TRENDS II-30
Orthopedics II-30
Innovations in Orthopedic Biomaterials: A Glance II-30
Synthetic Bone Grafts II-30
Combination of Bone Marrow and Bone Graft Substitute II-30
Demineralized Bone Matrices (DBMs) Market: Strong Growth but
Tough Competition II-31
Bone Morphogenetic Proteins II-31
GEM OS®1 Shows Promise II-32
geneX® Synthetic Bone Graft Substitute II-32
BoneCure Sleeve - Heading Towards the Human Market II-32
Bioactive Glass - Suitable for Weight Bearing Portion II-32
Tissue Engineered Cartilages - A Promising Solution for
Cartilage Repair II-32
Stem Cells to Support Tissue Engineering II-33
Cardiovascular Devices II-33
Stents II-34
Heart Valves II-34
Move towards Bioprosthetic Valves II-35
PTCA Devices II-35
Ventricular Assist Device II-36
Artificial Blood Vessels II-36
Artificial Blood II-36
Urology II-36
Dialysis II-37
Dermatology and Wound Care II-37
Surgery II-37
Biomaterials Mark Metamorphosis in Surgical Incision Closure
Market II-37
High Strength Surgical Adhesives Garner Growth with Biomaterials II-38
Orthodontics II-38
Nano-technology in Dental Fillings and Implants II-38
Biomaterials for Cosmetic Formulations II-39
Neurology II-39
Electrodes II-39
Biomaterials in Ophthalmology II-39
Materials for Drug Delivery Systems II-40
Polyethylene Glycol as a Drug Delivery System II-40
Hydrogels as Drug Delivery System II-40
Vinylic based Drug Delivery Systems II-40
Collagen Based Drug Delivery System II-40

5. REGULATORY ENVIRONMENT II-41
FDA Regulations II-41
American Society for Testing and Materials (ASTM) II-41
Joint Research Center (JRC) II-41
Biocompatibility Testing of Materials II-41
Testing Levels II-41
General Biocompatibility Testing II-41
Individual Biocompatibility Testing II-42
Testing Methods II-42

6. RECENT INDUSTRY ACTIVITY II-43
Amedica Corporation Ceases Biologic Distribution Agreement II-43
Glass Technology Services and Fame-Med Medical Trade Partners
to Develop Biocompatible Glass Ceramics II-43
InCube Labs Enters into Agreement with Engineering Research
Center II-43
Regentis Biomaterials Obtains CE Mark Approval for GelrinC II-43
Olympus Biotech International and BonAlive Biomaterials Enter
into Distribution Agreement II-43
Invibio Biomaterial Solutions to Introduce PEEK-Optima HA
Enhanced II-43
Coreleader Biotech Develops Novel Method for Biocompatible
Polymeric Fibre Manufacturing II-44
Purac Biomaterials to Construct a New Manufacturing Facility II-44
PetVivo Holdings Enters into Binding Term Sheet with Gel-Del
Technologies for Merger II-44

7. FOCUS ON SELECT PLAYERS II-45
AdvanSource Biomaterials Corporation (US) II-45
BASF Corporation (US) II-45
Berkeley Advanced Biomaterials, Inc. (US) II-45
Biomet, Inc. (US) II-46
BioMimetic Therapeutics LLC (US) II-46
BonAlive Biomaterials, Ltd. (Finland) II-47
Cam Bioceramics BV (Netherlands) II-47
Celanese Corporation (US) II-47
Corbion Purac (Netherlands) II-48
Evonik Industries AG (Germany) II-48
Exactech, Inc. (US) II-49
Hycail Finland OY (Finland) II-49
Invibio Biomaterial Solutions (UK) II-49
Morgan Technical Ceramics (UK) II-50
Nobel Biomaterials, Inc. (US) II-50
Royal DSM N.V. (The Netherlands) II-50
Stryker Corporation (US) II-51

8. GLOBAL MARKET PERSPECTIVE II-52
Table 7: World Recent Past, Current and Future Analysis for
Biocompatible Materials by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific, and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2013 through 2020 (includes corresponding
Graph/Chart) II-52

Table 8: World Historic Review for Biocompatible Materials by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2012
(includes corresponding Graph/Chart) II-53

Table 9: World 15-Year Perspective for Biocompatible Materials
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Canada, Japan, Europe, Asia-Pacific, and Rest of World
Markets for Years 2006, 2014 and 2020 (includes corresponding
Graph/Chart) II-54

Table 10: World Recent Past, Current and Future Analysis for
Polymeric Materials by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2013 through 2020 (includes corresponding Graph/Chart) II-55

Table 11: World Historic Review for Polymeric Materials by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2012
(includes corresponding Graph/Chart) II-56

Table 12: World 15-Year Perspective for Polymeric Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific, and Rest of World
Markets for Years 2006, 2014 and 2020 (includes corresponding
Graph/Chart) II-57

Table 13: World Recent Past, Current and Future Analysis for
Metallic Materials by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2013 through 2020 (includes corresponding Graph/Chart) II-58

Table 14: World Historic Review for Metallic Materials by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2012
(includes corresponding Graph/Chart) II-59

Table 15: World 15-Year Perspective for Metallic Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific, and Rest of World
Markets for Years 2006, 2014 and 2020 (includes corresponding
Graph/Chart) II-60

Table 16: World Recent Past, Current and Future Analysis for
Natural Materials by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2013 through 2020 (includes corresponding Graph/Chart) II-61

Table 17: World Historic Review for Natural Materials by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2012
(includes corresponding Graph/Chart) II-62

Table 18: World 15-Year Perspective for Natural Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific, and Rest of World
Markets for Years 2006, 2014 and 2020 (includes corresponding
Graph/Chart) II-63

Table 19: World Recent Past, Current and Future Analysis for
Other Materials by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific, and Rest of World Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2013 through 2020 (includes corresponding Graph/Chart) II-64

Table 20: World Historic Review for Other Materials by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2012
(includes corresponding Graph/Chart) II-65

Table 21: World 15-Year Perspective for Other Materials by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific, and Rest of World
Markets for Years 2006, 2014 and 2020 (includes corresponding
Graph/Chart) II-66


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Current and Future Analysis III-1
Orthopedic Biomaterials Market - An Overview III-1
Bone Graft Substitutes Market: Opportunities for Growth III-1
Growth in Regenerative Medicine Augers Well III-2
Implantable Regenerative Products Take Over Sports Medicine III-2
Cardiovascular Devices - A Potential Growth Market III-3
Regulatory Environment III-3
FDA Regulations III-3
Regulatory Challenges Limit Growth in the US Orthopedic
Biomaterials Market III-4
Recent Industry Activity III-4
Select Players III-5
B.Market Analytics III-9
Table 22: The US Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-9

Table 23: The US Historic Review for Biocompatible Materials
by Type - Polymeric Materials, Metallic Materials, Natural
Materials and Other Materials Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2006
through 2012 (includes corresponding Graph/Chart) III-10

Table 24: The US 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-11

2. CANADA III-12
A.Market Analysis III-12
Regenerative Medicine - An Advanced Market III-12
Favorable Growth Prospects in Bone Graft Substitutes Market III-12
B.Market Analytics III-13
Table 25: Canadian Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-13

Table 26: Canadian Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-14

Table 27: Canadian 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-15

3. JAPAN III-16
A.Market Analysis III-16
Current and Future Analysis III-16
An Overview III-16
Import Scenario: Implants III-16
Table 28: Japanese Percentage Imports by Implant Type
(includes corresponding Graph/Chart) III-17
Orthopedic Biomaterials Market III-17
Market for Cardiovascular Devices III-17
B.Market Analytics III-18
Table 29: Japanese Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-18

Table 30: Japanese Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-19

Table 31: Japanese 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-20

4. EUROPE III-21
A.Market Analysis III-21
Current and Future Analysis III-21
Orthopedic Biomaterials Market III-21
Synthetic Bone Graft Market Drives the BGS Market III-22
Dental Biomaterials Market in Europe: An Insight III-22
Cardiovascular Devices Market - Highly Diverse Europe III-22
Great Potential for Regenerative Medicine III-23
Regulatory Environment III-23
Government Regulations III-23
Key Players in Select Segments III-24
Table 32: European Market for Demineralized Bone Matrix by
Leading Companies/Organizations (2012): Percentage Market
Share Breakdown of Value Sales for Medtronic,
Musculoskeletal Transplant Foundation, RTI Surgical, Wright
Medical Technology and Others (includes corresponding
Graph/Chart) III-24
Recent Industry Activity III-24
B.Market Analytics III-25
Table 33: European Recent Past, Current and Future Analysis
for Biocompatible Materials by Geographic Region - France,
Germany, Italy, UK, and Rest of Europe Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2013 through 2020 (includes corresponding Graph/Chart) III-25

Table 34: European Historic Review for Biocompatible
Materials by Geographic Region - France, Germany, Italy, UK,
and Rest of Europe Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2012 (includes corresponding Graph/Chart) III-26

Table 35: European 15-Year Perspective for Biocompatible
Materials by Geographic Region - Percentage Breakdown of
Dollar Sales for France, Germany, Italy, UK, and Rest of
Europe Markets for Years 2006, 2014 and 2020 (includes
corresponding Graph/Chart) III-27

Table 36: European Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-28

Table 37: European Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-29

Table 38: European 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-30

4a. FRANCE III-31
Market Analysis III-31
Table 39: French Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-31

Table 40: French Historic Review for Biocompatible Materials
by Type - Polymeric Materials, Metallic Materials, Natural
Materials and Other Materials Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2006
through 2012 (includes corresponding Graph/Chart) III-32

Table 41: French 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-33

4b. GERMANY III-34
A.Market Analysis III-34
Current and Future Analysis III-34
Evonik Industries AG - A Key Player III-34
B.Market Analytics III-35
Table 42: German Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-35

Table 43: German Historic Review for Biocompatible Materials
by Type - Polymeric Materials, Metallic Materials, Natural
Materials and Other Materials Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2006
through 2012 (includes corresponding Graph/Chart) III-36

Table 44: German 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-37

4c. ITALY III-38
Market Analysis III-38
Table 45: Italian Recent Past, Current and Future Analysis
for Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-38

Table 46: Italian Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-39

Table 47: Italian15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-40

4d. THE UNITED KINGDOM III-41
A.Market Analysis III-41
Current and Future Analysis III-41
Implants Product Innovations are focused on Biomaterials III-41
Recent Industry Activity III-41
Select Players III-41
B.Market Analytics III-43
Table 48: UK Recent Past, Current and Future Analysis for
Biocompatible Materials by Type - Polymeric Materials,
Metallic Materials, Natural Materials and Other Materials
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-43

Table 49: UK Historic Review for Biocompatible Materials by
Type - Polymeric Materials, Metallic Materials, Natural
Materials and Other Materials Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2006
through 2012 (includes corresponding Graph/Chart) III-44

Table 50: UK 15-Year Perspective for Biocompatible Materials
by Type - Percentage Breakdown of Dollar Sales for Polymeric
Materials, Metallic Materials, Natural Materials and Other
Materials Markets for Years 2006, 2014 and 2020 (includes
corresponding Graph/Chart) III-45

4e. REST OF EUROPE III-46
A.Market Analysis III-46
Current and Future Analysis III-46
Recent Industry Activity III-46
Select Players III-46
B.Market Analytics III-49
Table 51: Rest of Europe Recent Past, Current and Future
Analysis for Biocompatible Materials by Type - Polymeric
Materials, Metallic Materials, Natural Materials and Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-49

Table 52: Rest of Europe Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-50

Table 53: Rest of Europe 15-Year Perspective for
Biocompatible Materials by Type - Percentage Breakdown of
Dollar Sales for Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets for Years
2006, 2014 and 2020 (includes corresponding Graph/Chart) III-51

5. ASIA-PACIFIC III-52
A.Market Analysis III-52
Current and Future Analysis III-52
Dental Bone Graft Substitutes and Biomaterials Market - An
Overview III-52
Table 54: Over 65 Years Individuals as % of Total
Population in Select Asian Countries (2012) (includes
corresponding Graph/Chart) III-52
Focus on Select Regions III-53
China III-53
Biomaterials Market Overview III-53
The Largest Biomaterial Research Country III-53
Orthopedic Biomaterials Market III-53
India III-53
Orthopedic Biomaterials Market III-53
Rise in Medical Tourism Drives Biomaterials Market III-54
Attractive Market for Prosthetic Heart Valves Device
Manufacturers III-54
B.Market Analytics III-55
Table 55: Asia-Pacific Recent Past, Current and Future
Analysis for Biocompatible Materials by Type - Polymeric
Materials, Metallic Materials, Natural Materials and Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-55

Table 56: Asia-Pacific Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-56

Table 57: Asia-Pacific 15-Year Perspective for Biocompatible
Materials by Type - Percentage Breakdown of Dollar Sales for
Polymeric Materials, Metallic Materials, Natural Materials
and Other Materials Markets for Years 2006, 2014 and 2020
(includes corresponding Graph/Chart) III-57

6. REST OF WORLD III-58
A.Market Analysis III-58
Current and Future Analysis III-58
Brazilian Biomaterial Market - Overview III-58
B.Market Analytics III-59
Table 58: Rest of World Recent Past, Current and Future
Analysis for Biocompatible Materials by Type - Polymeric
Materials, Metallic Materials, Natural Materials and Other
Materials Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-59

Table 59: Rest of World Historic Review for Biocompatible
Materials by Type - Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2006 through 2012 (includes corresponding Graph/Chart) III-60

Table 60: Rest of World 15-Year Perspective for
Biocompatible Materials by Type - Percentage Breakdown of
Dollar Sales for Polymeric Materials, Metallic Materials,
Natural Materials and Other Materials Markets for Years
2006, 2014 and 2020 (includes corresponding Graph/Chart) III-61


IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 59 (including Divisions/Subsidiaries - 64)

The United States (41)
Japan (2)
Europe (19)
- France (1)
- Germany (2)
- The United Kingdom (5)
- Rest of Europe (11)
Asia-Pacific (Excluding Japan) (1)
Middle East (1)

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