World Kidney Dialysis Equipment and Supplies Market

World Kidney Dialysis Equipment and Supplies Market

This report analyzes the worldwide markets for Kidney Dialysis Equipment and Supplies in US$ Million. The major dialysis modalities analyzed are Hemodialysis (HD) (Hemodialysis Machines, Blood Pumps, Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, & Other Supplies) and Peritoneal Dialysis (PD) (Peritoneal Dialysis Cycler Machines, Peritoneal Tubing Kits, Dialysates, and Catheters). The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Middle East, and Latin America. Annual forecasts are provided for each region for the period of 2006 through 2015. A ten-year historic analysis is also provided for these markets with annual market analytics. The report profiles 114 companies including many key and niche players worldwide such as Asahi Kasei Kuraray Medical Co., Ltd., Aksys Ltd., Baxter International, Inc., B. Braun Melsungen AG, DaVita Inc., Diaverum, Fresenius Medical Care AG & Co. KGaA, Fresenius Medical Care North America, Gambro AB, NxStage Medical Inc., Nikkiso Co., Ltd., Rockwell Medical Technologies, Inc., Sorin Group, and Teleflex Medical. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

KIDNEY DIALYSIS EQUIPMENT AND SUPPLIES MCP-3325
A GLOBAL STRATEGIC BUSINESS REPORT


CONTENTS

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
Hemodialysis (HD) I-4
Peritoneal Dialysis (PD) I-4


II . EXECUTIVE SUMMARY


1. Market Dynamics II-1
Global Dialysis Market - An Overview II-1
A Rapidly Expanding ESRD Patient Population II-1
Outlook II-2
Issues & Trends II-3
Aging Population - A Boosting Factor II-3
Driving Forces into the Future II-3
Changing Face of Dialysis Industry II-3
Innovations Spruce Up the Market II-4
Services Take the Driver’s Seat II-4
Emerging Markets to Drive Growth II-5
Home Hemodialysis - Opportunities for Growth II-5
Anemia - A Growing Concern Among Renal Failure Patients II-6
Barriers to Entry Significantly High in Dialyzers Market II-6
Pricing Pressures II-6
Service Providers Vary with Region(s) II-6
Table 1: Worldwide Dialysis Market (2007): Percentage
Breakdown of Value Sales by Segment for Dialysis Services,
Dialysis Products & Supplies II-6

Table 2: Leading Global Dialysis Clinic Operators (2007):
Percentage Breakdown by Number of Patients Treated for
Private Individual Operators, Public Sector, and Private
Companies (includes corresponding Graph/Chart) II-7
Consolidation Activity in the Services Sector II-7
Table 3: An Insight into Merger and Acquisition Activity in
the Dialysis Service Market (1996-2008) II-7
Patient Population Estimates II-8
Table 4: Number of ESRD Patients in the World (2004-2010)
(includes corresponding Graph/Chart) II-8

Table 5: Worldwide ESRD Prevalence Rates (in Per Million
Population) in Select Countries for 2005 (includes
corresponding Graph/Chart) II-9

Table 6: Worldwide Dialysis Patient Population (2007):
Percentage Breakdown of Number of Patients by Region for US,
European Union, Japan, Asia-Pacific, Latin America, and Rest
of World (includes corresponding Graph/Chart) II-9

Table 7: Worldwide Dialysis Prevalence Rates (in Patients Per
Million Population) in Select Regions/Countries (includes
corresponding Graph/Chart) II-9
Distribution of Dialysis Patients by Modality II-10
Table 8: Worldwide ESRD Treatments (2007): Percentage
Breakdown of Patient Population by Treatment Modality for
Hemodialysis, Peritoneal Dialysis, and Transplantation
(includes corresponding Graph/Chart) II-10

Table 9: ESRD Treatment in Select Countries (2007):
Percentage Breakdown of Patient Population by Treatment
Modality for Hemodialysis, Home Hemodialysis and CAPD/ CCPD
(includes corresponding Graph/Chart) II-10
US: Home to Largest Number of Hemodialysis Patients II-11
Table 10: Worldwide Dialysis Patient Population (2007):
Percentage Breakdown of Patients by Treatment Modality for
US, European Union, Japan, and Rest of World (includes
corresponding Graph/Chart) II-11

Table 11: Worldwide Dialysis Market (2008E): Percentage
Breakdown by Treatment Modality (includes corresponding
Graphs/Chart) II-11

2. Competitive Scenario II-12
‘Big Three’ Rule the Roost II-12
Dialysis Products and Services Market II-12
Table 12: Leading Players in the Global Dialysis Products
Market (2007): Percentage Breakdown of Value Sales for
Fresenius Medical Care, Baxter, Gambro and Others (includes
corresponding Graph/Chart) II-12

Table 13: Leading Players in the Worldwide Dialysis Market
(2007): Percentage Breakdown by Number of Patients for
Fresenius Medical Care, DaVita, Kuratorium für Dialyse,
Diaverum (former Gambro Healthcare), Dialysis Clinic
International, and Others (includes corresponding
Graph/Chart) II-12

Table 14: Leading Players in the Worldwide Hemodialysis
Products Market (2007): Percentage Breakdown of Value Sales
for Fresenius Medical Care, Gambro, Baxter, and Others
(includes corresponding Graph/Chart) II-13

Table 15: Leading Players in the Worldwide Peritoneal
Dialysis Products Market (2007) - Percentage Breakdown of
Sales for Baxter, Fresenius Medical Care, Gambro, and Others
(includes corresponding Graph/Chart) II-13

Table 16: Leading Players in the Worldwide Dialyzers Market
(2007): Percentage Breakdown of Unit Output for Fresenius
Medical Care, Gambro and Others (includes corresponding
Graph/Chart) II-13

Table 17: Leading Players in the Worldwide Dialysis Market
(2006 & 2007) - Breakdown by Number of Patients for
Fresenius Medical Care, DaVita, Kuratorium für Dialyse, and
Dialysis Clinic International (includes corresponding
Graph/Chart) II-14
Competitive Assessment of Leading players II-14
Ranking of Leading Players in Dialysis Products Market II-15

3. Introduction To Dialysis II-16
Dialysis - A Historical Perspective II-16
Kidney Disorders Addressed Through Dialysis II-17
Renal Failure II-17
Acute Renal Failure II-17
Chronic Renal Failure II-17
Renal Failure Caused by Diabetes II-18
Metabolic Disturbances in Chronic Renal Failure II-18
End-Stage Renal Disease II-18
Established Renal Failure II-18
Dialysis Methods II-19
Hemodialysis II-19
Side Effects Associated with Hemodialysis II-20
Cross-contaminated Hemodialysis Equipment Lead to
Bloodstream Infections II-20
Drugs Administered During Hemodialysis II-20
Automated Hemodialysis System II-20
Nocturnal Hemodialysis - A Promising Technique for Dialysis II-21
Peritoneal Dialysis II-21
Issues Related to Peritoneal Dialysis II-22
Types of Peritoneal Dialysis II-22
Continuous Peritoneal Dialysis (CAPD) II-22
Intermittent PD (IPD) II-22
Continuous Cycling Peritoneal Dialysis (CCPD) II-23
PD Plus Therapy II-23
Kidney Transplant: An Alternative to Dialysis II-23
Dialysis Preferred to Transplantation II-23
Enhancement of the Dialysis Process II-24
Decreasing Time of Treatment II-24
Decreasing the Size of Dialyzers II-24
Anatomy and Functioning of Human Kidney II-24
Measures to Avoid Kidney Failure II-25
Controlling Blood Pressure II-25
Diet II-25
Medication II-25
Reduced Consumption of Phosphate II-25

4. Review of Select Segments II-26
Hemodialysis Equipment and Supplies II-26
Hemodialysis Machines II-26
Cost/Benefit Scores over Improved Clinical Outcomes II-26
Blood Pumps II-26
Catheters II-26
Dialyzers II-27
Trends in the Dialyzer Market II-27
Synthetic Dialyzers Attain Mainstay II-27
Room for Innovation II-27
Increasing Penetration of Single-Use Dialyzers II-27
Dialysate II-28
Dialysis Tubing Kits II-28
Other Supplies II-28
Peritoneal Dialysis Equipment and Supplies II-28
Cyclers II-28
Tubing Set II-29
Dialysate II-29
Catheters II-29
Catheter-Related Complications of PD Technique II-29

5. Product Innovations/Introductions II-30
Teleflex Medical to Launch New Arrow® NextStep™ Catheter II-30
Angiotech to Unveil a New Hemostream™ Dialysis Catheter II-30
Fresenius Launches Liberty Cycler for Peritoneal Dialysis Therapy II-30
AngioDynamics Rolls Out Centros™, a Hemodialysis Access Catheter II-30
Renal Solutions Receives FDA Approval for Allient Sorbent
Dialysis System II-31
FDA Approves NovoSci’s D-Line Hemodialysis Catheters for the
US Market II-31
Merit Medical Launches New Dialysis Kit II-31
Nipro Launches Artificial Kidney Dialyzer II-31
Gambro Introduces New Dialysis Machine II-31
Arrow International Releases Chronic Hemodialysis Catheters II-32
Datascope Launches Chronic Dialysis Catheter II-32
Gambro Renal Products Develops Pediatric Dialyzer II-32
AngioDynamics Launches EvenMore Catheter II-32
FMC Launches Dialysis Machine II-32
Kawasumi Develops Kidney Dialyzer based on In-House Developed
Hollow Fibers II-32
AngioDynamics Introduces Dynamic Flow and AngioFlow II-33
Oregon State University Develops Microtechnology for Portable
Kidney Dialysis Machine II-33
Breakthrough Research By Veryan Medical to Save Life of
Dialysis Patients II-33

6. Recent Industry Activity II-34
Gambro Enters into Alliance with Sandoz II-34
Gambro Partners with Debiotech to Develop Peritoneal Dialysis
Cycler II-34
Aamaxan Transport Acquires Asian Business Management Group II-34
U.S. Renal Care Acquires Majority Stake in Eumana Home Dialysis II-34
Renal Advantage Acquires New Dialysis Facility in Florida II-34
DaVita Collaborates with Southwest Kidney Institute II-35
Alcavis International Merges with HDC Medical to Form Alcavis
HDC, LLC II-35
Ambulatory Services of America Buys Innovative Dialysis Systems II-35
RAI Acquires New Dialysis Center in Maryland II-35
Xcorporeal Merges with CT Holdings II-35
Mar Cor Acquires DSI’s Water-Related Assets II-36
Cantel Acquires Water Dialysis Operations of GE Water &
Process Technologies II-36
Datascope Sells ProGuide™ Chronic Dialysis Catheter to Merit
Medical II-36
Renal Solutions and Innovative Biotherapies Sign Collaborative
Agreement II-36
Rex Medical and Angiotech to Develop a New HemoStream Catheter II-36
Fresenius Expands Dialyzer Capacity at St. Wendel Plant II-36
Bridgepoint Acquires Gambro Healthcare Division II-37
FMC Acquires Excelsior II-37
Teleflex Acquires Arrow International II-37
NxStage Medical Takesover Medisystems Corp and Other
Affiliated Companies II-37
Baxter International Signs Partnership Deal for Home
Hemodialysis Machine II-38
DaVita and NxStage Ink Agreement for Joint Promotion of Home
Hemodialysis Equipment II-38
Nephros Receives Regulatory Sanction for Marketing
Hemodiafilters II-38
Bulgaria’s Etropal to Start New Production Line for Dialysis
Equipment II-39
Spectral Diagnostics Enters into Agreement with Toray Medical II-39
Aksys Shuts Down Dialysis Machine Plant II-39
Fresenius Takes Over Renal Solutions II-39
Gambro Divests HD Production Plant to Américo Govantes II-39
Fresenius Medical Care Acquires Renal Care Group II-40
National Quality Care Sells Chronic Care Dialysis Facility II-40
FMC Divests Kidney Dialysis Centers II-40
Renal Advantage Acquires Seven Dialysis Centers II-40
Dialysis Corporation of America Acquires Medicore II-40
Renal Solutions Signs Marketing Agreement with T-Med II-40
Baxter Distributes Hemodialysis Instruments of Gambro II-41
DaVita Acquires US Dialysis Services Business of Gambro II-41
Fresenius Acquires Haemotec II-41
DaVita Acquires Multiple Dialysis Centers II-41
Renal Care Group Signs Agreement with Preferred Medical Group II-41
Rockwell Signs Agreement with Multiple U.S. Dialysis
Manufacturers II-41
German Fresenius Renews Agreements with Kawasumi II-42
Renalworks Medical Corporation Comes into Being II-42
RITA Medical Merges with Horizon Medical II-42
Debiotech and Baxter Healthcare Enter Strategic Alliance II-42
FMC Enters into Alliance with Trivitron II-42
Sanmina-SCI Forms Alliance with Renal Solutions II-43
Kawasumi Laboratories Establishes New Dialyzers Facility in
Thailand II-43
Asahi Medical Constructs New Plants in China II-43
Gambro Closes Non-Synthetic Dialyzer Plants, Terminates
Agreement with Baxter II-43

7. Focus on Select Players II-44
Asahi Kasei Kuraray Medical Co., Ltd. (Japan) II-44
Aksys Ltd. (US) II-44
Baxter International, Inc. (US) II-44
B. Braun Melsungen AG (Germany) II-45
DaVita Inc. (US) II-45
Diaverum (Sweden) II-46
Fresenius Medical Care AG & Co. KGaA (Germany) II-46
Fresenius Medical Care North America (US) II-46
Gambro AB (Sweden) II-46
NxStage Medical Inc. (US) II-47
Nikkiso Co., Ltd. (Japan) II-47
Rockwell Medical Technologies, Inc. (US) II-48
Sorin Group (Italy) II-48
Teleflex Medical (US) II-48

8. Global Market Perspective II-50
Table 18: World Recent Past, Current & Future Analysis for
Kidney Dialysis Equipment and Supplies by Geographic Region -
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Middle East, and Latin America Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2006
through 2015 (includes corresponding Graphs/Chart) II-50

Table 19: World Historic Review for Kidney Dialysis Equipment
and Supplies by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-51

Table 20: World 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Geographic Region- Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets for Years 1998, 2008 & 2012 (includes corresponding
Graph/Chart) III-52

World Market for Kidney Dialysis Equipment and Supplies by
Segment II-53

Table 21: World Recent Past, Current & Future Analysis for
Hemodialysis Equipment and Supplies by Geographic Region- US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle
East, and Latin America Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-53

Table 22: World Historic Review for Hemodialysis Equipment and
Supplies by Geographic Region- US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-54

Table 23: World 15-Year Perspective for Hemodialysis Equipment
and Supplies by Geographic Region- Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets for
Years 1998, 2008 & 2012 (includes corresponding Graphs/Chart) II-55

Table 24: World Recent Past, Current & Future Analysis for
Hemodialysis Equipment and Supplies by Product Segment -
Hemodialysis Machines, Blood Pumps, Catheters, Dialyzers,
Dialysates, Dialysis Tubing Kits and Other Supplies Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 2006 through 2015 (includes corresponding Graphs/Chart) II-56

Table 25: World Historic Review for Hemodialysis Equipment and
Supplies by Product Segment - Hemodialysis Machines, Blood
Pumps, Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits
and Other Supplies Markets Independently Analyzed with Annual
Sales in US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) II-57

Table 26: World 15-Year Perspective for Hemodialysis Equipment
and Supplies by Product Segment- Percentage Breakdown of
Dollar Sales for Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits and
Other Supplies Markets for Years 1998, 2008 & 2012 (includes
corresponding Graphs/Chart) II-58

Table 27: World Recent Past, Current & Future Analysis for
Hemodialysis Machines by Geographic Region- US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Middle East, and Latin
America Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015
(includescorresponding Graphs/Chart) II-59

Table 28: World Historic Review for Hemodialysis Machines by
Geographic Region- US, Canada, Japan,Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding Graphs/Chart) II-60

Table 29: World 15-Year Perspective for Hemodialysis Machines
by Geographic Region- Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Middle East, and Latin America Markets for Years 1998, 2008 &
2012 (includes corresponding Graphs/Chart) II-61

Table 30: World Recent Past, Current & Future Analysis for
(Hemodialysis) Blood Pumps by Geographic Region- US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Middle East,
and Latin America Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2015
(includes corresponding Graphs/Chart) II-62

Table 31: World Historic Review for (Hemodialysis) Blood Pumps
by Geographic Region- US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding Graphs/Chart) II-63

Table 32: World 15-Year Perspective for (Hemodialysis) Blood
Pumps by Geographic Region- Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Middle East, and Latin America Markets for Years 1998,
2008 & 2012 (includes corresponding Graphs/Chart) II-64

Table 33: World Recent Past, Current & Future Analysis for
(Hemodialysis) Catheters by Geographic Region- US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Middle East,
and Latin America Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2016
(includes corresponding Graphs/Chart) II-65

Table 34: World Historic Review for (Hemodialysis) Catheters
by Geographic Region- US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding Graphs/Chart) II-66

Table 35: World 15-Year Perspective for (Hemodialysis)
Catheters by Geographic Region- Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Middle East, and Latin America Markets for Years 1998,
2008 & 2012 (includes corresponding Graphs/Chart) II-67

Table 36: World Recent Past, Current & Future Analysis for
(Hemodialysis) Dialyzers by Geographic Region- US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Middle East,
and Latin America Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2015
(includes corresponding Graphs/Chart) II-68

Table 37: World Historic Review for (Hemodialysis) Dialyzers
by Geographic Region- US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding Graphs/Chart) II-69

Table 38: World 15-Year Perspective for (Hemodialysis)
Dialyzers by Geographic Region- Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Middle East, and Latin America Markets for Years 1998,
2008 & 2012 (includes corresponding Graphs/Chart) II-70

Table 39: World Recent Past, Current & Future Analysis for
(Hemodialysis) Dialysates by Geographic Region- US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Middle East,
and Latin America Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2015
(includes corresponding Graphs/Chart) II-71

Table 40: World Historic Review for (Hemodialysis) Dialysates
by Geographic Region- US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding Graphs/Chart) II-72

Table 41: World 15-Year Perspective for (Hemodialysis)
Dialysates by Geographic Region- Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets for
Years 1998, 2008 & 2012 (includes corresponding Graphs/Chart) II-73

Table 42: World Recent Past, Current & Future Analysis for
(Hemodialysis) Dialysis Tubing Kits by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle
East, and Latin America Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-74

Table 43: World Historic Review for (Hemodialysis) Dialysis
Tubing Kits by Geographic Region- US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-75

Table 44: World 15-Year Perspective for (Hemodialysis)
Dialysis Tubing Kits by Geographic Region- Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets for Years 1998, 2008 & 2012 (includes corresponding
Graphs/Chart) II-76

Table 45: World Recent Past, Current & Future Analysis for
Other (Hemodialysis) Supplies by Geographic Region- US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle
East, and Latin America Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-77

Table 46: World Historic Review for Other (Hemodialysis)
Supplies by Geographic Region- US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-78

Table 47: World 15-Year Perspective for Other (Hemodialysis)
Supplies by Geographic Region- Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Middle East, and Latin America Markets for Years 1998,
2008 & 2012 (includes corresponding Graphs/Chart) II-79

Table 48: World Recent Past, Current & Future Analysis for
Peritoneal Dialysis Equipment & Supplies by Geographic Region-
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Middle East, and Latin America Markets Independently Analyzed
with Annual Sales in US$ Million for Years 2006 through 2015
(includes corresponding Graphs/Chart) II-80

Table 49: World Historic Review for Peritoneal Dialysis
Equipment & Supplies by Geographic Region- US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Middle East, and Latin
America Markets Independently Analyzed with Annual Sales in
US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) II-81

Table 50: World 15-Year Perspective for Peritoneal Dialysis
Equipment & Supplies by Geographic Region- Percentage
Breakdown of Dollar Sales for US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets for Years 1998, 2008 & 2012 (includes corresponding
Graphs/Chart) II-82

Table 51: World Recent Past, Current & Future Analysis for
Peritoneal Dialysis Equipment and Supplies by Product Segment-
Peritoneal Dialysis Cycler Machines, Peritoneal Tubing Kits,
Dialysates, and Catheters Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-83

Table 52: World Historic Review for Peritoneal Dialysis
Equipment and Supplies by Product Segment- Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters Markets Independently Analyzed with Annual Sales in
US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) II-84

Table 53: World 15-Year Perspective for Peritoneal Dialysis
Equipment and Supplies by Product Segment - Percentage
Breakdown of Dollar Sales for Peritoneal Dialysis Cycler
Machines, Peritoneal Tubing Kits, Dialysates, and Catheters
Markets for 1998, 2008 & 2012 (includes corresponding
Graphs/Chart) II-85

Table 54: World Recent Past, Current & Future Analysis for
Peritoneal Dialysis Cycler Machines by Geographic Region- US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle
East, and Latin America Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-86

Table 55: World Historic Review for Peritoneal Dialysis Cycler
Machines by Geographic Region- US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-87

Table 56: World 15-Year Perspective for Peritoneal Dialysis
Cycler Machines by Geographic Region- Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets for
Years 1998, 2008 & 2012 (includes corresponding Graphs/Chart) II-88

Table 57: World Recent Past, Current & Future Analysis for
Peritoneal Tubing Kits by Geographic Region- US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Middle East,
and Latin America Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2006 through 2015
(includes corresponding Graphs/Chart) II-89

Table 58: World Historic Review for Peritoneal Tubing Kits by
Geographic Region- US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding Graphs/Chart) II-90

Table 59: World 15-Year Perspective for Peritoneal Tubing Kits
by Geographic Region- Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Middle East, and Latin America Markets for Years 1998, 2008 &
2012 (includes corresponding Graphs/Chart) II-91

Table 60: World Recent Past, Current & Future Analysis for
(Peritoneal Dialysis) Dialysates by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle
East, and Latin America Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-92

Table 61: World Historic Review for (Peritoneal Dialysis)
Dialysates by Geographic Region- US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-93

Table 62: World 15-Year Perspective for (Peritoneal Dialysis)
Dialysates by Geographic Region- Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Middle East, and Latin America Markets for
Years 1998, 2008 & 2012 (includes corresponding Graphs/Chart) II-94

Table 63: World Recent Past, Current & Future Analysis for
(Peritoneal Dialysis) Catheters by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle
East, and Latin America Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2006 through
2015 (includes corresponding Graphs/Chart) II-95

Table 64: World Historic Review for (Peritoneal Dialysis)
Catheters by Geographic Region- US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Middle East, and Latin America
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) II-96

Table 65: World 15-Year Perspective for (Peritoneal Dialysis)
Catheters by Geographic Region- Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Middle East, and Latin America Markets for Years 1998,
2008 & 2012 (includes corresponding Graphs/Chart) II-97


III. MARKET

1. The United States III-1
A.Market Analysis III-1
Outlook III-1
Incidence of ESRD in the US III-1
Highlights III-1
Table 66: ESRD Patient Prevalence in the US (2000-2010)
(includes corresponding Graph/Chart) III-2
Table 67: US ESRD Patient Prevalence (2007-2008):
Percentage Breakdown of Patients by Age Group (includes
corresponding Graph/Chart) III-2

Table 68: US Dialysis Population Growth (2001-2010)
(includes corresponding Graphs/Chart) III-2

Table 69: Treatment Utilization for ESRD Patients in the
US (2005-2006): Percentage Breakdown of Number of
Patients Treated by Hemodialysis, Peritoneal Dialysis, and
Transplant (includes corresponding Graph/Chart) III-3

Table 70: Dialysis Treatment in the US (2007): Percentage
Breakdown of Number of Patients by Treatment Modality for
In-Centre HD, CCPD, CAPD, Home HD, and In-Centre Self HD
(includes corresponding Graph/Chart) III-3

Growing Role of Diabetes in ESRD Incidence III-4
Table 71: Leading Causes of ESRD (2005): Percentage
Breakdown of Number of Patients Alive by Primary Diagnosis
for Diabetes, Hypertension, Glomerulonephritis, Cystic
Kidney and Others (includes corresponding Graph/Chart) III-4

Home Hemodialysis- A Growing Market III-4
Table 72: US Recent Past, Current & Future Analysis for
Home Hemodialysis Machines Market with Annual Sales in US$
Million for the Period 2001 through 2010 (includes
corresponding Graph/Chart) III-5

Table 73: US Long-term Projections for Home Hemodialysis
Machines Market with Annual Sales in US$ Million for the
Period 2011 through 2015 (includes corresponding
Graph/Chart) III-5

Table 74: Leading Players in the US Home Hemodialysis
Products Market (2006): Percentage Share Breakdown of
Revenues for NxStage Medical, Fresenius, and Gambro
(includes corresponding Graph/Chart) III-5

Peritoneal Dialysis Population III-6
Dialysis Reimbursement - An Overview III-6
Current Reimbursement Scenario III-7
Table 75: Average Composite Rate & Drug Add-On
Freestanding Facilities (2005 & 2006) III-7

Reimbursements & Private Dialysis Care Providers III-8
Table 76: Medicare ESRD Patient Expenditure (2007):
Percentage Breakdown of Costs Incurred for
Hospitalization, Dialysis, EPO (Erythropoietin), Vitamin
D, Iron and Other Injectables, and Others (includes
corresponding Graph/Chart) III-8
Select Issues and Trends III-8
Clinics Move Towards Single Use Dialyzers III-8
Dialysis Withdrawal: Major Cause of High Death Rates III-9

Overview of the US Dialysis Service Industry III-9
Table 77: Leading US. Dialysis Services Providers (2005) -
Ranked by Number of Patients and Clinics for Fresenius
Medical Care, DaVita Inc, Dialysis Clinic Inc, Renal
Advantage Inc., American Renal Associates, Liberty
Dialysis, Dialysis Corporation of America, and National
Renal Alliance (includes corresponding Graph/Chart) III-9

Table 78: Leading Dialysis Service Providers in the US
(2005): Percentage Breakdown by Patient Population for
DaVita, Fresenius Medical Care, Renal Care Group, Dialysis
Clinics Inc, Renal Advantage and Others (includes
corresponding Graph/Chart) III-10

Table 79: Leading Dialysis Service Providers in the US
(2007): Percentage Breakdown by Patient Population for
Fresenius Medical Care, DaVita, and Others (includes
corresponding Graph/Chart) III-10

Table 80: Leading US Dialysis Service Operators (2007) -
Percentage Breakdown by Number of Patients Treated in the
Private Sector, Private Independent Operators, and Public
Sector (includes corresponding Graph/Chart) III-10

Competitive Scenario in the US Kidney Dialysis Equipment and
Supplies Market III-10
Table 81: US Dialysis Products Market (2005): Percentage
Breakdown of Value Sales for Leading Players- Fresenius
Medical Care, Baxter, Gambro and Others (includes
corresponding Graph/Chart) III-11

Hemodialysis Market III-11
Table 82: Leading Players in the U.S. Hemodialysis Market
-2004) - Percentage Breakdown of Sales for Fresenius,
Baxter, Gambro and Others (includes corresponding
Graphs/Chart) III-11

Table 83: Leading Players in the US Hemodialyzers Market
(2007) - Percentage Breakdown of Sales for Fresenius,
Baxter, Gambro and Others (includes corresponding
Graph/Chart) III-11

Peritoneal Dialysis Market III-12
Table 84: Leading Players in the US Peritoneal Dialysis
Market (2004) - Percentage Breakdown of Sales for Baxter
and Fresenius III-12
Product Launches III-12
Strategic Corporate Developments III-14
Select Players III-20
B.Market Analytics III-23
Table 85: US Recent Past, Current & Future Analysis for
Kidney Dialysis Equipment and Supplies by Product Group/
Segment- Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-23

Table 86: US Historic Review for Kidney Dialysis Equipment
and Supplies by Product Group/Segment - Hemodialysis
(Hemodialysis Machines, Blood Pumps, Catheters, Dialyzers,
Dialysates, Dialysis Tubing Kits, and Other Supplies) and
Peritoneal Dialysis (Peritoneal Dialysis Cycler Machines,
Peritoneal Tubing Kits, Dialysates, and Catheters) Markets
Independently Analyzed with Annual Sales in US$ Million for
Years 1996 through 2005 (includes corresponding
Graphs/Chart) III-24

Table 87: US 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Product Group/Segment - Percentage
Breakdown of Dollar Sales for Hemodialysis (Hemodialysis
Machines, Blood Pumps, Catheters, Dialyzers, Dialysates,
Dialysis Tubing Kits, and Other Supplies) and Peritoneal
Dialysis (Peritoneal Dialysis Cycler Machines, Peritoneal
Tubing Kits, Dialysates, and Catheters) Markets for 1998,
2008 & 2012 III-25

2. Canada III-26
A.Market Analysis III-26
Outlook III-26
Strategic Corporate Developments III-26
B.Market Analytics III-27
Table 88: Canadian Recent Past, Current & Future Analysis
for Kidney Dialysis Equipment and Supplies by Product Group/
Segment - Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-27

Table 89: Canadian Historic Review for Kidney Dialysis
Equipment and Supplies by Product Group/ Segment -
Hemodialysis (Hemodialysis Machines, Blood Pumps, Catheters,
Dialyzers, Dialysates, Dialysis Tubing Kits, and Other
Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
in US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) III-28

Table 90: Canadian 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Product Group/ Segment -
Percentage Breakdown of Dollar Sales for Hemodialysis
(Hemodialysis Machines, Blood Pumps, Catheters, Dialyzers,
Dialysates, Dialysis Tubing Kits, and Other Supplies) and
Peritoneal Dialysis (Peritoneal Dialysis Cycler Machines,
Peritoneal Tubing Kits, Dialysates, and Catheters) Markets
for 1998, 2008 & 2012 III-29

3. Japan III-30
A.Market Analysis III-30
Outlook III-30
Patient Population III-30
Dialysis Services III-30
Table 91: Leading Japanese Dialysis Service Operators
(2007) - Percentage Breakdown by Number of Patients Treated
in Dialysis Clinics Operated by Private Nephrologists and
Public Sector III-30
Competitive Scenario III-30
Table 92: Leading Players in the Japanese Kidney Dialyzers
Market ( 2004) - Percentage Breakdown of Sales for Asahi
Medical, Nissho, Kawasumi, Toray, and Others (includes
corresponding Graphs/Chart) III-31
Product Launch III-31
Strategic Corporate Developments III-31
Select Players III-32
B.Market Analytics III-35
Table 93: Japanese Recent Past, Current & Future Analysis
for Kidney Dialysis Equipment and Supplies by Product Group/
Segment - Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-35

Table 94: Japanese Historic Review for Kidney Dialysis
Equipment and Supplies by Product Group/ Segment -
Hemodialysis (Hemodialysis Machines, Blood Pumps, Catheters,
Dialyzers, Dialysates, Dialysis Tubing Kits, and Other
Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
in US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) III-36

Table 95: Japanese 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Product Group/Segment - Percentage
Breakdown of Dollar Sales for Hemodialysis (Hemodialysis
Machines, Blood Pumps, Catheters, Dialyzers, Dialysates,
Dialysis Tubing Kits, and Other Supplies) and Peritoneal
Dialysis (Peritoneal Dialysis Cycler Machines, Peritoneal
Tubing Kits, Dialysates, and Catheters) Markets for 1998,
2008 & 2012 III-37

4. Europe III-38
A.Market Analysis III-38
Outlook III-38
Patient Population III-38
Factors Affecting the Market III-38
Trend Towards Privatization III-38
Leading Dialysis Services Providers III-38
Table 96: Leading Dialysis Services Providers in Europe
(2003-2005) - Percentage Breakdown by Number of Patients
for Fresenius Medical Care, Kuratorium, Gambro,
Patienten-Heimversorgung, Baxter, and Other Providers
(includes corresponding Graph/Chart) III-39

Table 97: Leading European Dialysis Operators (2007):
Percentage Breakdown by Number of Patents Treated in
Dialysis Clinics Operated by the Public Sector, Private
Individual Operators and Private Companies (includes
corresponding Graph/Chart) III-39
Competitive Scenario III-40
Table 98: Leading Players in the West European Dialysis
Product Market (2005) - Percentage Breakdown of Sales for
Fresenius, Gambro and Others (includes corresponding
Graphs/Chart) III-40
B.Market Analytics III-40
Table 99: European Recent Past, Current & Future Analysis
for Kidney Dialysis Equipment and Supplies by Geographic
Region- France, Germany, Italy, UK, Spain, Russia, and Rest
of Europe Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-40

Table 100: European Historic Review for Kidney Dialysis
Equipment and Supplies by Geographic Region- France,
Germany, Italy, UK, Spain, Russia, and Rest of Europe
Markets Independently Analyzed with Annual Sales in US$
Million for Years 1996 through 2005 (includes corresponding
Graphs/Chart) III-41

Table 101: European 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Geographic Region - Percentage
Breakdown of Dollar Sales for France, Germany, Italy, UK,
Spain, Russia, and Rest of Europe Markets for Years 1998,
2008 & 2012 (includes corresponding Graphs/Chart) III-42

Table 102: European Recent Past, Current & Future Analysis
for Kidney Dialysis Equipment and Supplies by Product Group/
Segment - Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-43

Table 103: European Historic Review for Kidney Dialysis
Equipment and Supplies by Product Group/Segment -
Hemodialysis (Hemodialysis Machines, Blood Pumps, Catheters,
Dialyzers, Dialysates, Dialysis Tubing Kits, and Other
Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
in US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) III-44

Table 104: European 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Product Group/ Segment -
Percentage Breakdown of Dollar Sales for Hemodialysis
(Hemodialysis Machines, Blood Pumps, Catheters, Dialyzers,
Dialysates, Dialysis Tubing Kits, and Other Supplies) and
Peritoneal Dialysis (Peritoneal Dialysis Cycler Machines,
Peritoneal Tubing Kits, Dialysates, and Catheters) Markets
for 1998, 2008 & 2012 III-45

4a. France III-46
Market Analysis III-46
Outlook III-46
Table 105: French Recent Past, Current & Future Analysis for
Kidney Dialysis Equipment and Supplies by Product Group/
Segment - Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-46

Table 106: French Historic Review for Kidney Dialysis
Equipment and Supplies by Product Group/Segment -
Hemodialysis (Hemodialysis Machines, Blood Pumps, Catheters,
Dialyzers, Dialysates, Dialysis Tubing Kits, and Other
Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
in US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) III-47

Table 107: French 15-Year Perspective for KidneyDialysis
Equipment and Supplies by Product Group/Segment - Percentage
Breakdown of Dollar Sales for Hemodialysis (Hemodialysis
Machines, Blood Pumps, Catheters, Dialyzers, Dialysates,
Dialysis Tubing Kits, and Other Supplies) and Peritoneal
Dialysis (Peritoneal Dialysis Cycler Machines, Peritoneal
Tubing Kits, Dialysates, and Catheters) Markets for 1998,
2008 & 2012 III-48

4b. Germany III-49
A.Market Analysis III-49
Outlook III-49
Dialysis Services III-49
Product Launches III-49
Strategic Corporate Developments III-50
Select Players III-51
B. Braun Melsungen AG III-51
Fresenius Medical Care AG III-51
B.Market Analytics III-52
Table 108: German Recent Past, Current & Future Analysis for
Kidney Dialysis Equipment and Supplies by Product Group/
Segment - Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-52

Table 109: German Historic Review for Kidney Dialysis
Equipment and Supplies by Product Group/ Segment -
Hemodialysis (Hemodialysis Machines, Blood Pumps, Catheters,
Dialyzers, Dialysates, Dialysis Tubing Kits, and Other
Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
in US$ Million for Years 1996 through 2005 (includes
corresponding Graphs/Chart) III-53

Table 110: German 15-Year Perspective for Kidney Dialysis
Equipment and Supplies by Product Group/ Segment -
Percentage Breakdown of Dollar Sales for Hemodialysis
(Hemodialysis Machines, Blood Pumps, Catheters, Dialyzers,
Dialysates, Dialysis Tubing Kits, and Other Supplies) and
Peritoneal Dialysis (Peritoneal Dialysis Cycler Machines,
Peritoneal Tubing Kits, Dialysates, and Catheters) Markets
for 1998, 2008 & 2012 III-54

4c. Italy III-55
A.Market Analysis III-55
Outlook III-55
Sorin Group - A Key Player III-55
B.Market Analytics III-56
Table 111: Italian Recent Past, Current & Future Analysis
for Kidney Dialysis Equipment and Supplies by Product Group/
Segment - Hemodialysis (Hemodialysis Machines, Blood Pumps,
Catheters, Dialyzers, Dialysates, Dialysis Tubing Kits, and
Other Supplies) and Peritoneal Dialysis (Peritoneal Dialysis
Cycler Machines, Peritoneal Tubing Kits, Dialysates, and
Catheters) Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2006 through 2015 (includes
corresponding Graphs/Chart) III-5