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Brain Injury - Pipeline Review, H1 2015

  • January 2015
  • -
  • Global Markets Direct
  • -
  • 43 pages

Brain Injury - Pipeline Review, H1 2015

Summary

Global Markets Direct’s, ‘Brain Injury - Pipeline Review, H1 2015’, provides an overview of the Brain Injury’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Brain Injury, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Brain Injury and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Brain Injury
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in the therapeutics development for Brain Injury and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects
- A review of the Brain Injury products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Brain Injury pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Brain Injury
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Brain Injury pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Contents

Brain Injury - Pipeline Review, H1 2015
Table of Contents
Introduction 5
Global Markets Direct Report Coverage 5
Brain Injury Overview 6
Therapeutics Development 7
Pipeline Products for Brain Injury - Overview 7
Pipeline Products for Brain Injury - Comparative Analysis 8
Brain Injury - Therapeutics under Development by Companies 9
Brain Injury - Therapeutics under Investigation by Universities/Institutes 10
Brain Injury - Pipeline Products Glance 11
Early Stage Products 11
Brain Injury - Products under Development by Companies 12
Brain Injury - Products under Investigation by Universities/Institutes 13
Brain Injury - Companies Involved in Therapeutics Development 14
Acorda Therapeutics, Inc. 14
Biogen Idec Inc. 15
Chiesi Farmaceutici SpA 16
Faron Pharmaceuticals Oy 17
Virogenomics, Inc. 18
Brain Injury - Therapeutics Assessment 19
Assessment by Monotherapy Products 19
Assessment by Target 20
Assessment by Mechanism of Action 22
Assessment by Route of Administration 24
Assessment by Molecule Type 25
Drug Profiles 26
Enzyme to Inhibit Chondroitin Sulfate Proteoglycan for Spinal Cord Injury and Brain Injury - Drug Profile 26
Product Description 26
Mechanism of Action 26
RandD Progress 26
interferon beta-1a - Drug Profile 28
Product Description 28
Mechanism of Action 28
RandD Progress 28
Peptide to Inhibit Pannexin-1 for Brain Injury - Drug Profile 30
Product Description 30
Mechanism of Action 30
RandD Progress 30
PRE-084 - Drug Profile 31
Product Description 31
Mechanism of Action 31
RandD Progress 31
Recombinant Interleukin-34 to Agonize GM-CSFR for Alzheimer's Disease and Brain Injury - Drug Profile 32
Product Description 32
Mechanism of Action 32
RandD Progress 32
Recombinant Protein to Agonize GM-CSFR for Alzheimer's Disease and Brain Injury - Drug Profile 33
Product Description 33
Mechanism of Action 33
RandD Progress 33
RTL-551 - Drug Profile 34
Product Description 34
Mechanism of Action 34
RandD Progress 34
Small Molecules to Block TRPC3 for Acute Brain Injury - Drug Profile 35
Product Description 35
Mechanism of Action 35
RandD Progress 35
Small Molecules to Inhibit Caspase-2 for Neonatal Brain Injury - Drug Profile 36
Product Description 36
Mechanism of Action 36
RandD Progress 36
Synthetic Peptide to Inhibit Factor II for Thrombosis, Restenosis and Brain Injury - Drug Profile 37
Product Description 37
Mechanism of Action 37
RandD Progress 37
Brain Injury - Recent Pipeline Updates 38
Brain Injury - Dormant Projects 40
Brain Injury - Discontinued Products 41
Appendix 42
Methodology 42
Coverage 42
Secondary Research 42
Primary Research 42
Expert Panel Validation 42
Contact Us 43
Disclaimer 43

List of Tables

Number of Products under Development for Brain Injury, H1 2015 7
Number of Products under Development for Brain Injury - Comparative Analysis, H1 2015 8
Number of Products under Development by Companies, H1 2015 9
Number of Products under Investigation by Universities/Institutes, H1 2015 10
Comparative Analysis by Early Stage Development, H1 2015 11
Products under Development by Companies, H1 2015 12
Products under Investigation by Universities/Institutes, H1 2015 13
Brain Injury - Pipeline by Acorda Therapeutics, Inc., H1 2015 14
Brain Injury - Pipeline by Biogen Idec Inc., H1 2015 15
Brain Injury - Pipeline by Chiesi Farmaceutici SpA, H1 2015 16
Brain Injury - Pipeline by Faron Pharmaceuticals Oy, H1 2015 17
Brain Injury - Pipeline by Virogenomics, Inc., H1 2015 18
Assessment by Monotherapy Products, H1 2015 19
Number of Products by Stage and Target, H1 2015 21
Number of Products by Stage and Mechanism of Action, H1 2015 23
Number of Products by Stage and Route of Administration, H1 2015 24
Number of Products by Stage and Molecule Type, H1 2015 25
Brain Injury Therapeutics - Recent Pipeline Updates, H1 2015 38
Brain Injury - Dormant Projects, H1 2015 40
Brain Injury - Discontinued Products, H1 2015 41

List of Figures

Number of Products under Development for Brain Injury, H1 2015 7
Number of Products under Development for Brain Injury - Comparative Analysis, H1 2015 8
Number of Products under Investigation by Universities/Institutes, H1 2015 10
Comparative Analysis by Early Stage Products, H1 2015 11
Assessment by Monotherapy Products, H1 2015 19
Number of Products by Top 10 Targets, H1 2015 20
Number of Products by Stage and Top 10 Targets, H1 2015 20
Number of Products by Top 10 Mechanism of Actions, H1 2015 22
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 22
Number of Products by Top 10 Molecule Types, H1 2015 25

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