Global Medical Markets for Nanoscale Materials and Devices

• Publication date: July 2008

Describes various medical applications for nanomaterials including diagnostics, pharmaceuticals, medical devices and medical imaging Determines the current market status for naomaterials and nanodevices used in medical applications, and makes forecasts over a five-year period from 2008 to 2013 Includes a thorough patent analysis Discusses developments that could affect the long-term market for nanomaterials and nanodevices in medical applications...

Describes various medical applications for nanomaterials including diagnostics, pharmaceuticals, medical devices and medical imaging Determines the current market status for naomaterials and nanodevices used in medical applications, and makes forecasts over a five-year period from 2008 to 2013 Includes a thorough patent analysis Discusses developments that could affect the long-term market for nanomaterials and nanodevices in medical applications including environmental and safety issues.  
 

Global Medical Devices Industry

INTRODUCTION

STUDY BACKGROUND

STUDY GOALS AND OBJECTIVES

INTENDED AUDIENCE

SCOPE OF REPORT

INFORMATION SOURCES AND METHODOLOGY

ANALYST CREDENTIALS

RELATED BCC RESEARCH REPORTS

BCC ONLINE SERVICES

DISCLAIMER

EXECUTIVE SUMMARY

SUMMARY TABLE MEDICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

SUMMARY FIGURE MEDICAL MARKET FOR NANOTECHNOLOGY APPLICATION, BY TYPE OF APPLICATION, 2007-2018 (%)

OVERVIEW

TYPES OF NANOTECHNOLOGY WITH MEDICAL APPLICATIONS

NANOMATERIALS

TABLE 1 MAJOR CATEGORIES OF NANOMATERIALS USED IN MEDICAL APPLICATIONS

TABLE 1 (CONTINUED)

Solid Nanoparticles

Hollow Nanoparticles

Nanoscale Thin Films and Coatings

Nanostructured Monolithics

Nanocomposites

Nanotools

Nanodevices

MEDICAL APPLICATIONS OF NANOTECHNOLOGY

MEDICAL RESEARCH

TABLE 2 MEDICAL RESEARCH APPLICATIONS OF NANOTECHNOLOGY

CLINICAL DIAGNOSTICS

TABLE 3 CLINICAL DIAGNOSTIC APPLICATIONS OF NANOTECHNOLOGY

PHARMACEUTICALS

TABLE 4 PHARMACEUTICAL APPLICATIONS OF NANOTECHNOLOGY

MEDICAL DEVICES

TABLE 5 MEDICAL DEVICE APPLICATIONS OF NANOTECHNOLOGY

MEDICAL IMAGING

TABLE 6 MEDICAL IMAGING APPLICATIONS OF NANOTECHNOLOGY

MARKET SIZE AND SEGMENTATION

MARKET SIZE

FIGURE 1 TRENDS IN GLOBAL MARKET FOR NANOMEDICAL APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 1 (CONTINUED)

APPLICATION SEGMENTS

FIGURE 2 GLOBAL NANOMEDICAL MARKET BY TYPE OF APPLICATION, 2007-2013 ($ MILLIONS)

FIGURE 2 (CONTINUED)

TABLE 7 MEDICAL MARKET FOR NANOMATERIALS AND NANODEVICES, BY APPLICATION, THROUGH 2013 ($ MILLIONS)

NANOTECHNOLOGY SEGMENTS

TABLE 8 MEDICAL MARKET FOR DIFFERENT TYPES OF NANOTECHNOLOGIES, THROUGH 2018 ($ MILLIONS)

FIGURE 3 GLOBAL NANOMEDICAL MARKET BY TYPE OF NANOTECHNOLOGY, 2007-2013 ($ MILLIONS)

MEDICAL RESEARCH MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018

SUMMARY

TABLE 9 MEDICAL RESEARCH MARKET FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLION)

FIGURE 4 TRENDS IN CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

TABLE 10 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

FIGURE 5 TRENDS IN MEDICAL RESEARCH MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

COMMERCIAL APPLICATIONS

TABLE 11 MEDICAL RESEARCH MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 12 GLOBAL MARKET FOR NANO-HPLC APPLICATIONS, THROUGH 2018 ($ MILLIONS)

MAGNETIC SEPARATIONS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 13 GLOBAL MARKET FOR IRON OXIDE NANOPARTICLES IN BIOMAGNETIC SEPARATIONS, THROUGH 2018 ($ MILLIONS)

TRANSFECTON REAGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 14 GLOBAL MARKET FOR DENDRIMER-BASED TRANSFECTON REAGENTS, THROUGH 2018 ($ MILLIONS)

MEMBRANE SEPARATION

Nanotechnology Application

Commercial and Regulatory Status

Projected Market

TABLE 15 GLOBAL MARKET FOR NANOMEMBRANES USED IN BIOMEDICAL RESEARCH APPLICATIONS, THROUGH 2018 ($ MILLIONS)

NANOMANIPULATORS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 16 GLOBAL MARKET FOR NANOMANIPULATORS IN MEDICAL RESEARCH APPLICATIONS, THROUGH 2018 ($MILLIONS)

PRE-COMMERCIAL AND DEVELOPMENTAL APPLICATIONS

APTAMER PROTEOMICS ARRAYS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 17 GLOBAL MARKET FOR APTAMER PROTEOMICS ARRAYS, THROUGH 2018 ($ MILLIONS)

CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2017-2018

SUMMARY

TABLE 18 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

FIGURE 6 TRENDS IN CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

TABLE 19 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

FIGURE 7 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLION)

COMMERCIAL APPLICATIONS

TABLE 20 CLINICAL DIAGNOSTIC MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

BIOLOGICAL MARKERS AND DETECTION AIDS

Nanotechnology Applications

Gold Nanoparticles

Dendrimers

Iron Oxide

Quantum Dots

Commercial and Regulatory Status

Projected Market

TABLE 21 WORLD MARKETS FOR NANOPARTICLES IN BIODETECTION AND LABELING APPLICATIONS, THROUGH 2018 ($ MILLIONS)

FIGURE 8 TRENDS NANOPARTICLES USED FOR BIODETECTION AND LABELING APPLICATIONS, 2007-2018 ($ MILLIONS)

Colloidal Gold

Dendrimers

Iron Oxide

Quantum Dots

PRE-COMMERCIAL AND DEVELOPMENTAL APPLICATIONS

TABLE 22 CLINICAL DIAGNOSTIC MARKETS FOR PRECOMMERCIAL AND DEVELOPMENTAL NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

NANOSHELL-BASED WHOLE BLOOD IMMUNOASSAYS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 23 WORLD MARKETS FOR NANOSHELL-BASED REAGENTS USED IN WHOLE BLOOD IMMUNOASSAYS, THROUGH 2013 ($ MILLIONS)

SALIVA BASED DIAGNOSTICS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 24 WORLD MARKETS FOR NANOTECHNOLOGY-BASED POC SALIVA TESTS, THROUGH 2018 ($ MILLIONS)

NANOWIRE-BASED BIOMARKER SENSORS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 25 WORLD MARKETS FOR NANOWIRE-BASED BIOMARKER POC TESTS, THROUGH 2018 ($ MILLIONS)

BIOBARCODE ASSAYS

Nanotechnology Applications

Commercial and Regulatory Status

Potential Markets

TABLE 26 WORLD MARKETS FOR BIOBARCODE-BASED MOLECULAR DIAGNOSTIC TEST REAGENTS, THROUGH 2018 ($ MILLIONS)

CARBON NANOTUBE-BASED DNA DETECTOR

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 27 WORLD MARKETS FOR NANOTUBE-BASED DNA PROBES, THROUGH 2018 ($ MILLIONS)

PHARMACEUTICAL MARKETS FOR NANOTECHNOLOGY APPLICATIONS, 2017-2018

SUMMARY

TABLE 28 PHARMACEUTICAL-RELATED MARKET FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

FIGURE 9 TRENDS IN PHARMACEUTICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

TABLE 29 PHARMACEUTICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

FIGURE 10 TRENDS IN PHARMACEUTICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

COMMERCIAL APPLICATIONS

TABLE 30 PHARMACEUTICAL MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

ENHANCED-SOLUBILITY DRUG COMPOUNDS

Nanotechnology Applications

TABLE 31 NANOTECHNOLOGY-BASED APPROACHES TO ENHANCING WATER SOLUBILITY OF HYDROPHOBIC DRUGS

Nanocrystal (Elan)

Commercial and Regulatory Status

Projected Market

TABLE 32 ESTIMATED SALES OF COMMERCIAL DRUGS FORMULATED USING ELAN NANOCRYSTAL TECHNOLOGY, 2007 ($ MILLIONS)

TABLE 33 GLOBAL MARKET FOR DRUGS FORMULATED USING ELAN NANOCRYSTAL TECHNOLOGY, THROUGH 2018 ($ MILLIONS)

NANOLIPOSOME-ENCLOSED CANCER DRUG

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 34 GLOBAL MARKET FOR NANOLIPOSOME-ENCLOSED CANCER DRUGS, THROUGH 2018 ($ MILLIONS)

NANOPHOSPHOLIPID-BASED HORMONE THERAPIES

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 35 GLOBAL MARKET FOR NANOPHOSPHOLIPID-BASED TRANSDERMAL HORMONE THERAPIES, THROUGH 2018 ($ MILLIONS)

APTAMER-BASED AMD THERAPY

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 36 GLOBAL MARKET FOR MACUGEN APTAMER-BASED AMD DRUG, THROUGH 2018 ($ MILLIONS)

PRE-COMMERCIAL AND DEVELOPMENTAL APPLICATIONS

TABLE 37 PHARMACEUTICAL MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY UNDER DEVELOPMENT, THROUGH 2018 ($ MILLIONS)

TABLE 37 (CONTINUED)

MICROBIOCIDAL GEL

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 38 GLOBAL MARKET FOR VIVAGEL DENDRIMER-BASED MICROBIOCIDAL GEL, THROUGH 2018 ($ MILLIONS)

BRACHYTHERAPY TREATMENT

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 39 GLOBAL MARKET FOR BRACHYSIL NANOSTRUCTURED BRACHYTHERAPY PRODUCTS, THROUGH 2018 ($MILLIONS)

NON-SMALL-CELL LUNG CANCER SUPPRESSOR

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 40 GLOBAL MARKET FOR NANOPARTICLE-BASED NSCLC THERAPIES, THROUGH 2018 ($ MILLIONS)

NANOPARTICLE PACLITAXEL

Nanotechnology Applications

DO/NDR/02

NK 105

Nanoshell-Encapsulated Paclitaxel

Transferrin-Coated Paclitaxel Nanoparticles

Commercial and Regulatory Status

Projected Market

TABLE 41 GLOBAL MARKET FOR NANOPARTICLE PACLITAXEL THERAPEUTICS, THROUGH 2018 ($ MILLIONS)

COLLOIDAL GOLD-BASED CANCER THERAPEUTICS

Nanotechnology Applications

Commercial and Regulatory Status

Potential Market

TABLE 42 GLOBAL MARKET FOR COLLOIDAL GOLD-BASED CANCER THERAPEUTICS, THROUGH 2018 ($ MILLIONS)

NANOBOMBS

Nanotechnology Applications

Carbon Nanotube Bomb

Porous Silicon Nanobomb

Dendrimer Nanobomb

Dual Chamber Nanobomb

Commercial and Regulatory Status

Projected Market

TABLE 43 GLOBAL MARKET FOR ANTI-CANCER NANOBOMBS, THROUGH 2018 ($ MILLIONS)

MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS

SUMMARY

TABLE 44 MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

FIGURE 11 TRENDS IN MEDICAL DEVICE MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

TABLE 45 MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

FIGURE 12 TRENDS IN MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

COMMERCIAL APPLICATIONS

TABLE 46 MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

BONE SUBSTITUTES

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 47 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED SYNTHETIC BONE SUBSTITUTES, THROUGH 2018 ($ MILLIONS)

ANTIMICROBIAL DRESSINGS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

Projected Market (continued)

TABLE 48 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED ANTIMICROBIAL APPLICATIONS, THROUGH 2018 ($ MILLIONS)

SPINTRONIC SENSORS FOR MEDICAL DEVICES

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 49 GLOBAL MARKET FOR SPINTRONICS-BASED MEDICAL SENSORS, THROUGH 2018 ($ MILLIONS)

SURGICAL TOOLS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 50 GLOBAL MARKET FOR NANOSCALE DIAMOND SURGICAL INSTRUMENT COATINGS, THROUGH 2018 ($ MILLIONS)

SUTURE NEEDLES

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 51 GLOBAL MARKET FOR NANOSTRUCTURED STEEL SUTURE NEEDLES, THROUGH 2018 ($ MILLIONS)

MEDICAL APPAREL

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 52 GLOBAL MARKET FOR NANOSTRUCTURED SILVER YARN FOR MEDICAL APPAREL, THROUGH 2018 ($ MILLIONS)

NANOCOMPOSITE MEDICAL TUBING

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 53 GLOBAL MARKET FOR NYLON/CLAY NANOCOMPOSITES IN MEDICAL TUBING APPLICATONS, THROUGH 2018 ($ MILLIONS)

MEDICAL DEVICE INFECTION CONTROL

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 54 GLOBAL MARKET FOR SILVER NANOPARTICLE ANTIMICROBIAL COATINGS FOR MEDICAL DEVICES, THROUGH 2018 ($ MILLIONS)

PRE-COMMERCIAL AND DEVELOPMENTAL APPLICATIONS

TABLE 55 MEDICAL DEVICE MARKETS FOR PRE-COMMERCIAL AND DEVELOPMENTAL NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 55 (CONTINUED)

MRI-SAFE COATINGS FOR MEDICAL DEVICES

Nanotechnology Applications

Commercial and Regulatory Status

Potential Market

TABLE 56 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED MRISAFE COATING APPLICATIONS, THROUGH 2018 ($ MILLIONS)

BIOCOMPATIBLE COATINGS FOR MEDICAL DEVICES AND IMPLANTS

Nanotechnology Applications

Commercial and Regulatory Status

Potential Markets

TABLE 57 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED CORONARY STENT APPLICATIONS, THROUGH 2018 ($ MILLIONS)

NANOSTRUCTURED TITANIUM IMPLANTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 58 GLOBAL MARKET FOR NANOSTRUCTURED TITANIUM IMPLANTS, THROUGH 2018 ($ MILLIONS)

LONG-LASTING NANOHORN FUEL CELLS FOR MEDICAL DEVICES

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 59 GLOBAL MARKET FOR NANOHORN-BASED FUEL CELLS FOR MEDICAL IMPLANTS, THROUGH 2018 ($ MILLIONS)

NANOTUBE-BASED RESPIRATORY MONITORS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 60 GLOBAL SALES OF SPIROMETERS AND CAPNOMETERS, THROUGH 2013 ($ MILLIONS)

Projected Market (Continued)

TABLE 61 GLOBAL MARKET FOR NANOTUBE-BASED RESPIRATORY GAS MONITORS, THROUGH 2018 ($ MILLIONS)

RETINAL IMPLANTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS

SUMMARY

TABLE 62 MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS

FIGURE 13 TRENDS IN MEDICAL IMAGING MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

TABLE 63 MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

FIGURE 14 TRENDS IN MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

COMMERCIAL APPLICATIONS

TABLE 64 MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

SUPERPARAMAGNETIC MAGNETIC RESONANCE IMAGING (MRI) CONTRAST AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

TABLE 65 SUPERPARAMAGNETIC IRON OXIDE CONTRAST MEDIA: REGULATORY AND MARKETING STATUS

TABLE 65 (CONTINUED)

Projected Market

TABLE 66 GLOBAL MARKET FOR NANOPARTICULATE IRON OXIDE USED IN MRI CONTRAST MEDIA, THROUGH 2018 ($ MILLIONS)

SCANNING PROBE MICROSCOPE TIPS

Nanotechnology Applications

Commercial Status

Projected Market

TABLE 67 GLOBAL CARBON NANOTUBES USED IN SCANNING PROBE MICROSCOPE TIPS, THROUGH 2018 ($ MILLION)

NANOPARTICLE-BASED OPTICAL IMAGING AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 68 GLOBAL MARKET FOR NANOPARTICLE-BASED FLUORESCENT IMAGING AGENTS, THROUGH 2018 ($ MILLIONS)

PRE-COMMERCIAL AND DEVELOPMENTAL APPLICATIONS

TABLE 69 MEDICAL IMAGING MARKETS FOR PRE-COMMERCIAL AND DEVELOPMENTAL NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

NANOTUBE FIELD EMISSION X-RAY TUBES

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 70 GLOBAL MARKET FOR CARBON NANOTUBE FIELDEMITTER X-RAY TUBES, THROUGH 2018 ($ MILLIONS)

ORGANIC LIGHT-EMITTING DIODES SURGICAL DISPLAYS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 71 GLOBAL MARKET FOR OLEDS IN SURGICAL DISPLAYS, THROUGH 2018 ($ MILLIONS)

METAL NANOSHELL PHOTONICS-BASED IMAGING CONTRAST AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 72 GLOBAL MARKET FOR METAL NANOSHELLS IN IMAGING AND THERAPEUTIC APPLICATIONS, THROUGH 2018 ($ MILLIONS)

APTAMER MOLECULAR IMAGING AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Markets

TABLE 73 GLOBAL MARKET FOR APTAMER IMAGING AGENTS IN MOLECULAR IMAGING, THROUGH 2018 ($ MILLIONS)

FULLERENE MAGNETIC RESONANCE IMAGING AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Projected Market

TABLE 74 GLOBAL MARKET FOR FULLERENE-BASED IMAGING AGENTS IN MRI, THROUGH 2018 ($ MILLIONS)

GOLD NANOROD IMAGING AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Potential Markets

TABLE 75 GLOBAL MARKET FOR GOLD NANOROD-BASED IMAGING AGENTS, THROUGH 2018 ($ MILLIONS)

OTHER NANOSCALE IMAGING AGENTS

Nanotechnology Applications

Commercial and Regulatory Status

Potential Markets

INDUSTRY STRUCTURE

FIRM SIZE

FIGURE 15 NANO-MEDICAL FIRMS BY SIZE (PERCENTAGE OF TOTAL COMPANIES ANALYZED)

MAIN PRODUCT LINES

FIGURE 16 NANO-MEDICAL FIRMS BY MAIN PRODUCT LINE (PERCENTAGE OF TOTAL COMPANIES ANALYZED)

NANOMEDICAL FIRMS BY NATIONALITY

FIGURE 17 NANOMEDICAL FIRMS BY MAIN PRODUCT LINE (PERCENTAGE OF TOTAL COMPANIES ANALYZED)

APPENDIX 1: COMPANY PROFILES

AAP IMPLANTATE AG

ACRYMED, INC.

ALZA CORP.

AMAG PHARMACEUTICALS, INC

ANGSTROM MEDICA, INC.

APHIOS CORP

APPLIED NANODETECTORS LTD.

APPLIED NEUROSOLUTIONS, INC.

BANGS LABORATORIES, INC

BERKELEY ADVANCED BIOMATERIALS, INC

BIOPHAN TECHNOLOGIES, INC.

CAPSULUTION NANOSCIENCE AG

CYTIMMUNE SCIENCES, INC.

DEBIOTECH SA

DENDRITECH, INC

DENDRITIC NANOTECHNOLOGIES INC.

DIONEX CORP.

DOW CHEMICAL CO.

DYNAL BIOTECH ASA

EKSIGENT TECHNOLOGIES, LLC

ELAN CORPORATION, PLC

EMD CHEMICALS, INC.

EVIDENT TECHNOLOGIES

FLAMEL TECHNOLOGIES SA

FOSTER CORP.

GESELLSCHAFT FÜR DIAMANTPRODUKE MBH

HYOSUNG CORP

INFRAMAT CORP

INTEGRATED NANO-TECHNOLOGIES, LLC

INTROGEN THERAPEUTICS, INC.

INVITROGEN CORP

JR NANOTECH PLC

MAD CITY LABS, INC.

MAGNABIOSCIENCES LLC

MESOSYSTEMS/ICX

MICROCOSM, INC

MICRO-TECH SCIENTIFIC INC

MICROMOD PARTIKELTECHNOLOGIE GMBH

MIV THERAPEUTICS, INC.

NANOCARRIER CORP., LTD.

NANOMIX, INC

NANOPEUTICS SRO

NANOPROBES, INC.

NANO SCIENCE DIAGNOSTICS, INC.

NANOSPECTRA BIOSCIENCES, INC.

NANOSPHERE, INC

NOVAVAX, INC

NPOINT, INC

NUCRYST PHARMACEUTICALS

NVE CORP.

ORASURE TECHNOLOGIES, INC

ORTHOVITA, INC

OSI PHARMACEUTICALS, INC

OXONICA, LTD.

PHARMASOL GMBH

POLYSCIENCES INC.

PSIVIDA INC.

QUIAGEN N.V

SALVONA LLC

SANDVIK MATERIALS TECHNOLOGY AB

SIMPORE INC.

SKYEPHARMA PLC

SOMALOGIC, INC.

SPIRE CORP

STARPHARMA PTY LTD

SURFACINE DEVELOPMENT CO. LLC

TEGO BIOSCIENCES CORP

VISEN MEDICAL INC

VISTA THERAPEUTICS, INC

FIGURE 18 BIOMEDICAL MARKET FOR NANOWIRE SENSORS (%)

XINTEK, INC

ZYVEX CORP

APPENDIX 2: PATENT ANALYSIS

PATENTS BY TYPE OF APPLICATION

FIGURE 19 U.S. NANO-MEDICAL PATENTS BY APPLICATION SEGMENT (PERCENTAGE OF IDENTIFIED PATENTS ISSUED THROUGH JUNE 1, 2008)

FIGURE 19 (CONTINUED)

MAJOR IP PORTFOLIOS

TABLE 76 MAJOR HOLDERS OF US NANOMEDICAL PATENTS (NUMBER OF PATENTS HELD AS OF JUNE 1, 2008)

LIST OF TABLES

SUMMARY TABLE MEDICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018

TABLE 1 MAJOR CATEGORIES OF NANOMATERIALS USED IN MEDICAL APPLICATIONS

TABLE 2 MEDICAL RESEARCH APPLICATIONS OF NANOTECHNOLOGY

TABLE 3 CLINICAL DIAGNOSTIC APPLICATIONS OF NANOTECHNOLOGY

TABLE 4 PHARMACEUTICAL APPLICATIONS OF NANOTECHNOLOGY

TABLE 5 MEDICAL DEVICE APPLICATIONS OF NANOTECHNOLOGY

TABLE 6 MEDICAL IMAGING APPLICATIONS OF NANOTECHNOLOGY

TABLE 7 MEDICAL MARKET FOR NANOMATERIALS AND NANODEVICES, BY APPLICATION, THROUGH 2013 ($ MILLIONS)

TABLE 9 MEDICAL RESEARCH MARKET FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLION)

TABLE 10 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

TABLE 11 MEDICAL RESEARCH MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

TABLE 12 GLOBAL MARKET FOR NANO-HPLC APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 13 GLOBAL MARKET FOR IRON OXIDE NANOPARTICLES IN BIOMAGNETIC SEPARATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 14 GLOBAL MARKET FOR DENDRIMER-BASED TRANSFECTON REAGENTS, THROUGH 2018 ($ MILLIONS)

TABLE 15 GLOBAL MARKET FOR NANOMEMBRANES USED IN BIOMEDICAL RESEARCH APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 16 GLOBAL MARKET FOR NANOMANIPULATORS IN MEDICAL RESEARCH APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 17 GLOBAL MARKET FOR APTAMER PROTEOMICS ARRAYS, THROUGH 2018 ($ MILLIONS)

TABLE 18 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 19 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

TABLE 20 CLINICAL DIAGNOSTIC MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

TABLE 21 WORLD MARKETS FOR NANOPARTICLES IN BIODETECTION AND LABELING APPLICATIONS, THROUGH 2018 |($ MILLIONS)

TABLE 22 CLINICAL DIAGNOSTIC MARKETS FOR PRE-COMMERCIAL AND DEVELOPMENTAL NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 23 WORLD MARKETS FOR NANOSHELL-BASED REAGENTS USED IN WHOLE BLOOD IMMUNOASSAYS, THROUGH 2013

($ MILLIONS)

TABLE 24 WORLD MARKETS FOR NANOTECHNOLOGY-BASED POC SALIVA TESTS, THROUGH 2018 ($ MILLIONS)

TABLE 25 WORLD MARKETS FOR NANOWIRE-BASED BIOMARKER POC TESTS, THROUGH 2018 ($ MILLIONS)

TABLE 26 WORLD MARKETS FOR BIOBARCODE-BASED MOLECULAR DIAGNOSTIC TEST REAGENTS, THROUGH 2018 ($ MILLIONS)

TABLE 27 WORLD MARKETS FOR NANOTUBE-BASED DNA PROBES, THROUGH 2018 ($ MILLIONS)

TABLE 28 PHARMACEUTICAL-RELATED MARKET FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 29 PHARMACEUTICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

TABLE 30 PHARMACEUTICAL MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

TABLE 31 NANOTECHNOLOGY-BASED APPROACHES TO ENHANCING WATER SOLUBILITY OF HYDROPHOBIC DRUGS

TABLE 32 ESTIMATED SALES OF COMMERCIAL DRUGS FORMULATED USING ELAN NANOCRYSTAL TECHNOLOGY, 2007 ($ MILLIONS)

TABLE 33 GLOBAL MARKET FOR DRUGS FORMULATED USING ELAN NANOCRYSTAL TECHNOLOGY, THROUGH 2018 ($ MILLIONS)

TABLE 34 GLOBAL MARKET FOR NANOLIPOSOME-ENCLOSED CANCER DRUGS, THROUGH 2018 ($ MILLIONS)

TABLE 35 GLOBAL MARKET FOR NANOPHOSPHOLIPID-BASED TRANSDERMAL HORMONE THERAPIES, THROUGH 2018 ($ MILLIONS)

TABLE 36 GLOBAL MARKET FOR MACUGEN APTAMER-BASED AMD DRUG, THROUGH 2018 ($ MILLIONS)

TABLE 37 PHARMACEUTICAL MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY UNDER DEVELOPMENT, THROUGH 2018 ($ MILLIONS)

TABLE 38 GLOBAL MARKET FOR VIVAGEL DENDRIMER-BASED MICROBIOCIDAL GEL, THROUGH 2018 ($ MILLIONS)

TABLE 39 GLOBAL MARKET FOR BRACHYSIL NANOSTRUCTURED BRACHYTHERAPY PRODUCTS, THROUGH 2018 ($ MILLIONS)

TABLE 40 GLOBAL MARKET FOR NANOPARTICLE-BASED NSCLC THERAPIES, THROUGH 2018 ($ MILLIONS)

TABLE 41 GLOBAL MARKET FOR NANOPARTICLE PACLITAXEL THERAPEUTICS, THROUGH 2018 ($ MILLIONS)

TABLE 42 GLOBAL MARKET FOR COLLOIDAL GOLD-BASED CANCER THERAPEUTICS, THROUGH 2018 ($ MILLIONS)

TABLE 43 GLOBAL MARKET FOR ANTI-CANCER NANOBOMBS, THROUGH 2018 ($ MILLIONS)

TABLE 44 MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 45 MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

TABLE 46 MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

TABLE 47 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED SYNTHETIC BONE SUBSTITUTES, THROUGH 2018 ($ MILLIONS)

TABLE 48 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED ANTIMICROBIAL APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 49 GLOBAL MARKET FOR SPINTRONICS-BASED MEDICAL SENSORS, THROUGH 2018 ($ MILLIONS)

TABLE 50 GLOBAL MARKET FOR NANOSCALE DIAMOND SURGICAL INSTRUMENT COATINGS, THROUGH 2018 ($ MILLIONS)

TABLE 51 GLOBAL MARKET FOR NANOSTRUCTURED STEEL SUTURE NEEDLES, THROUGH 2018 ($ MILLIONS)

TABLE 52 GLOBAL MARKET FOR NANOSTRUCTURED SILVER YARN FOR MEDICAL APPAREL, THROUGH 2018 ($ MILLIONS)

TABLE 53 GLOBAL MARKET FOR NYLON/CLAY NANOCOMPOSITES IN MEDICAL TUBING APPLICATONS, THROUGH 2018 ($ MILLIONS)

TABLE 54 GLOBAL MARKET FOR SILVER NANOPARTICLE ANTIMICROBIAL COATINGS FOR MEDICAL DEVICES, THROUGH 2018 ($ MILLIONS)

TABLE 55 MEDICAL DEVICE MARKETS FOR PRE-COMMERCIAL AND DEVELOPMENTAL NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 56 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED MRISAFE COATING APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 57 GLOBAL MARKET FOR NANOTECHNOLOGY-BASED CORONARY STENT APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 58 GLOBAL MARKET FOR NANOSTRUCTURED TITANIUM IMPLANTS, THROUGH 2018 ($ MILLIONS)

TABLE 59 GLOBAL MARKET FOR NANOHORN-BASED FUEL CELLS FOR MEDICAL IMPLANTS, THROUGH 2018 ($ MILLIONS)

TABLE 60 GLOBAL SALES OF SPIROMETERS AND CAPNOMETERS, THROUGH 2013 ($ MILLIONS)

TABLE 61 GLOBAL MARKET FOR NANOTUBE-BASED RESPIRATORY GAS MONITORS, THROUGH 2018 ($ MILLIONS)

TABLE 62 MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS

TABLE 63 MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, THROUGH 2018 ($ MILLIONS)

TABLE 64 MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS CURRENTLY IN COMMERCIAL USE, THROUGH 2018 ($ MILLIONS)

TABLE 65 SUPERPARAMAGNETIC IRON OXIDE CONTRAST MEDIA: REGULATORY AND MARKETING STATUS

TABLE 66 GLOBAL MARKET FOR NANOPARTICULATE IRON OXIDE USED IN MRI CONTRAST MEDIA, THROUGH 2018 ($ MILLIONS)

TABLE 67 GLOBAL CARBON NANOTUBES USED IN SCANNING PROBE MICROSCOPE TIPS, THROUGH 2018 ($ MILLION)

TABLE 68 GLOBAL MARKET FOR NANOPARTICLE-BASED FLUORESCENT IMAGING AGENTS, THROUGH 2018 ($ MILLIONS)

TABLE 69 MEDICAL IMAGING MARKETS FOR PRE-COMMERCIAL AND DEVELOPMENTAL NANOTECHNOLOGY APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 70 GLOBAL MARKET FOR CARBON NANOTUBE FIELDEMITTER X-RAY TUBES, THROUGH 2018 ($ MILLIONS)

TABLE 71 GLOBAL MARKET FOR OLEDS IN SURGICAL DISPLAYS, THROUGH 2018 ($ MILLIONS)

TABLE 72 GLOBAL MARKET FOR METAL NANOSHELLS IN IMAGING AND THERAPEUTIC APPLICATIONS, THROUGH 2018 ($ MILLIONS)

TABLE 73 GLOBAL MARKET FOR APTAMER IMAGING AGENTS IN MOLECULAR IMAGING, THROUGH 2018 ($ MILLIONS)

TABLE 74 GLOBAL MARKET FOR FULLERENE-BASED IMAGING AGENTS IN MRI, THROUGH 2018 ($ MILLIONS)

TABLE 75 GLOBAL MARKET FOR GOLD NANOROD-BASED IMAGING AGENTS, THROUGH 2018 ($ MILLIONS)

TABLE 76 MAJOR HOLDERS OF US NANOMEDICAL PATENTS (NUMBER OF PATENTS HELD AS OF JUNE 1, 2008)

LIST OF FIGURES

SUMMARY FIGURE MEDICAL MARKET FOR NANOTECHNOLOGY APPLICATION, BY TYPE OF APPLICATION, 2007-2018 (%)

FIGURE 1 TRENDS IN GLOBAL MARKET FOR NANOMEDICAL APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 2 GLOBAL NANOMEDICAL MARKET BY TYPE OF APPLICATION, 2007-2013 ($ MILLIONS)

FIGURE 3 GLOBAL NANOMEDICAL MARKET BY TYPE OF NANOTECHNOLOGY, 2007-2013 ($ MILLIONS)

FIGURE 4 TRENDS IN CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($MILLIONS)

FIGURE 5 TRENDS IN MEDICAL RESEARCH MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

FIGURE 6 TRENDS IN CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 7 CLINICAL DIAGNOSTIC MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($MILLION)

FIGURE 8 TRENDS NANOPARTICLES USED FOR BIODETECTION AND LABELING APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 9 TRENDS IN PHARMACEUTICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 10 TRENDS IN PHARMACEUTICAL MARKET FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

FIGURE 11 TRENDS IN MEDICAL DEVICE MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 12 TRENDS IN MEDICAL DEVICE MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

FIGURE 13 TRENDS IN MEDICAL IMAGING MARKET FOR NANOTECHNOLOGY APPLICATIONS, 2007-2018 ($ MILLIONS)

FIGURE 14 TRENDS IN MEDICAL IMAGING MARKETS FOR NANOTECHNOLOGY APPLICATIONS BY TYPE OF NANOTECHNOLOGY, 2007-2018 ($ MILLIONS)

FIGURE 15 NANO-MEDICAL FIRMS BY SIZE (PERCENTAGE OF TOTAL COMPANIES ANALYZED)

FIGURE 16 NANO-MEDICAL FIRMS BY MAIN PRODUCT LINE (PERCENTAGE OF TOTAL COMPANIES ANALYZED)

FIGURE 17 NANOMEDICAL FIRMS BY MAIN PRODUCT LINE (PERCENTAGE OF TOTAL COMPANIES ANALYZED)

FIGURE 18 BIOMEDICAL MARKET FOR NANOWIRE SENSORS (%)

FIGURE 19 U.S. NANO-MEDICAL PATENTS BY APPLICATION SEGMENT (PERCENTAGE OF IDENTIFIED PATENTS ISSUED THROUGH JUNE 1, 2008)