Excipients in Pharmaceuticals

  • October 2013
  • -
  • BCC Research
  • -
  • 229 pages

REASON FOR THE STUDY

Among the significant forces that continue to affect the global excipients industry in 2013 are problems in the global supply chain, the demands of Quality by Design (QbD) and concerns about drug safety. Positive trends include the development of creative ideas in response to the need for new excipients, and new levels of cooperation between major players. These forces are reshaping the global market for excipients.

GOALS AND OBJECTIVES

The primary goals of this report are to provide a detailed analysis of the excipients market today and a forecast of what the market will look like in 5 years. The specific objectives are to identify excipients being used; quantify global market volumes; track important developments; analyze the structure of the industry and its driving forces; and provide data with which the reader can further evaluate the excipients industry and marketplace.

AUDIENCE

As a market and technology summary, this report consolidates a wide range of industrial and technical information that should aid excipient suppliers, chemical companies, drug manufacturers, healthcare regulators and congressional staffers keep current with today’s marketplace. The report should be of value to companies interested in entering or expanding their involvement in the field. The report should provide senior marketing personnel and executive planners with insight about what materials can best satisfy customer demands. Market projections may be of interest to venture capitalists interested in exploring commercialization opportunities, as well as companies and personnel involved in designing and constructing chemical and excipient manufacturing plants and/or those who service such plants. The report offers useful background to consultants in the field. The report can serve as an introductory resource for newcomers to the business, including new employees. In addition, the report can offer background to governmental officials examining reform.

SCOPE OF REPORT

Excipients in Pharmaceuticals offers coverage of the most important issues surrounding excipients: technological, regulatory, economic, political and so on.
Excluded from the study are ingredients for cosmetics, personal care, food, quasi-medical, unorthodox, alternative, home remedies, underground and/or illegal drugs and veterinary drugs.
This report organizes information from diverse sources into sections entitled Summary, Overview, Technology, Industry Structure and Company Profiles. The Summary encapsulates several key conclusions and includes a table of market findings. The Overview provides deep background on the burning issues of the day, including the global supply chain crisis, QbD and legislative prospects. The Technology section examines excipients by chemical compounds, functional uses, and delivery systems, and as finished products. The Industry Structure section discusses the market environment, strategies, influences, market shares, international aspects and other related factors. The Company Profiles segment provides summaries of more than 120 companies that supply excipients or are relevant to the industry.

METHODOLOGY AND INFORMATION SOURCES

Both primary and secondary research methodologies were used in preparing this study. The methodology used to create Excipients in Pharmaceuticals included extensive telephone interviews with key executives of leading U.S. and European companies and consultancies. This commentary was combined with information gleaned from websites, annual reports, the trade press, textbooks, patents, press releases and government documents.

The information has been used to project and forecast market size, and calculate compound annual growth rates (CAGRs) of the overall market and many market segments. All market sizes refer to worldwide values and volumes, which are rounded to the nearest million in dollars and pounds. Market size is estimated at the manufacturer level; that is, the level of consumption in actual drug formulations. Where precise information was not available, a determination was made using a formulation of reasonable assumptions and estimates based on historical data. In this report, the market size for 2012 serves as a base for making estimates for 2013 and projections to 2018.

ANALYST CREDENTIALS

Paul Evers has been involved in analyzing pharmaceutical and medical markets for 20 years. He is the author of several previous BCC reports on various aspects of the pharmaceutical marketplace including the excipients sector, as well as analyses of major trends and the pharmaceutical regulatory environment.

REPORT HIGHLIGHTS

This report provides:
• An overview of the global market for excipients in pharmaceuticals, including examinations of the effects of a crisis in the global supply chain, the demands of quality by design (QbD), and concerns about drug safety
• Analyses of global market trends, with data from 2012, estimates for 2013, and projections of compound annual growth rates (CAGRs) through 2018
• Discussion of positive trends in the industry, including the development of creative ideas in response to the need for new excipients and new levels of cooperation between major players
• Coverage of the most important issues surrounding excipients: technological, regulatory, economic, and political
• Evaluations of excipient technology by chemical compounds, functional uses, delivery systems and finished products
• Comprehensive company profiles of suppliers and others relevant to the industry.

Table Of Contents

TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 2

REASON FOR THE STUDY 2
GOALS AND OBJECTIVES 2
AUDIENCE 2
SCOPE OF REPORT 2
METHODOLOGY AND INFORMATION SOURCES 3
ANALYST CREDENTIALS 3
RELATED BCC REPORTS 3
BCC ON-LINE SERVICES 4
DISCLAIMER 4

CHAPTER 2 SUMMARY 6

SUMMARY TABLE GLOBAL EXCIPIENT MARKET BY MATERIAL TYPE, THROUGH 2018
($ MILLIONS) 6
SUMMARY FIGURE GLOBAL EXCIPIENT MARKET, 2011-2018 ($ MILLIONS) 6

CHAPTER 3 OVERVIEW 11

WHAT IS AN EXCIPIENT? 11
THE PHARMACEUTICALS INDUSTRY IN TURMOIL: 2000 TO TODAY 12
THE KNOWLEDGE CRISIS 13
THE NEED FOR NEW EXCIPIENTS 15
A NOTE ABOUT DIRECT COMPRESSION 17
COPROCESSING IS SPLENDID, BUT IT IS NOT ENOUGH 17
QBD AND THE GLOBAL SUPPLY CHAIN CRISIS: TWO TIDAL WAVES 18
HOW AND WHY THE QUALITY APPROACH CAME TO PHARMA 18
THE BASICS OF QBD 21
THE GLOBAL SUPPLY CHAIN CRISIS 24
RECENT REGULATORY MOVES 29
INTERNATIONAL 29
EUROPE 30
CHINA 31
HOW DOES THE WORKFORCE COPE? 32
EXCIPIENTS AND THE RECESSION 32

CHAPTER 4 GLOBAL EXCIPIENT MARKET: SEVERAL BASIC FIGURES 34

FIGURE 1 GLOBAL EXCIPIENT MARKET SHARE BY CATEGORY OF MATERIAL, 2013
(%) 34
FIGURE 2 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF ORGANIC CHEMICAL,
2013 (%) 34
FIGURE 3 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF INORGANIC CHEMICAL,
2013 (%) 35
FIGURE 4 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF USP WATER, 2013 (%) 35
FIGURE 5 GLOBAL EXCIPIENT MARKET SHARE BY FUNCTIONAL USE, 2013 (%) 36
FIGURE 6 GLOBAL EXCIPIENT MARKET SHARE BY TYPE OF DELIVERY SYSTEM, 2013
(%) 37
FIGURE 7 GLOBAL EXCIPIENT MARKET SHARE FOR FINISHED PRODUCTS BY TYPE
(RX AND OTC), 2013 (%) 37

CHAPTER 5 CHEMICAL COMPOUNDS 40

MARKET SIZE 40
TABLE 1 GLOBAL EXCIPIENT MARKET VALUE BY MATERIAL TYPE, THROUGH 2018 ($
MILLIONS) 41
TABLE 2 GLOBAL EXCIPIENT MARKET VOLUME BY MATERIAL TYPE, THROUGH 2018
(LBS MILLIONS) 41
ORGANIC CHEMICALS 41
MARKET SIZE FOR ORGANIC CHEMICALS 41
TABLE 3 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VALUE BY TYPE,
THROUGH 2018 ($ MILLIONS) 42
TABLE 4 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VOLUME BY TYPE,
THROUGH 2018 (LBS MILLIONS) 42
CARBOHYDRATES 42
Market Size 43
TABLE 5 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 43
TABLE 6 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 43
Celluloses 43
Market Size 43
TABLE 7 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 44
TABLE 8 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 44
Microcrystalline Cellulose 44
Market Size 45
TABLE 9 GLOBAL MCC EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 45
Cellulose Ethers 45
Market Size 46
TABLE 10 GLOBAL CELLULOSE ETHER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 46
Cellulose Esters 47
Market Size 47
TABLE 11 GLOBAL CELLULOSE ESTER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 47
Carboxymethyl Cellulose and Croscarmellose Sodium 48
Market Size 48
TABLE 12 GLOBAL CMC AND CROSCARMELLOSE EXCIPIENT MARKET, THROUGH
2018 ($ MILLIONS/LBS MILLIONS) 48
Sugars 48
Market Size 48
TABLE 13 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 48
TABLE 14 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018 (MILLION
LBS) 49
Actual Sugars 49
Market Size 49
TABLE 15 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 50
TABLE 16 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 50
Lactose 50
Market Size 51
TABLE 17 GLOBAL LACTOSE EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 51
Sucrose 51
Market Size 51
TABLE 18 GLOBAL SUCROSE EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 52
Dextrose (Glucose) 52
Market Size 52
TABLE 19 GLOBAL DEXTROSE (GLUCOSE) EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 52
Sugar Alcohols 52
Market Size 53
TABLE 20 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE,
THROUGH 2018 ($ MILLIONS) 53
TABLE 21 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE,
THROUGH 2018 (LBS MILLIONS) 53
Sorbitol 53
Market Size 54
TABLE 22 GLOBAL SORBITOL EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 54
Mannitol 54
Market Size 54
TABLE 23 GLOBAL MANNITOL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 55
Other Sugar Alcohols 55
Market Size 55
TABLE 24 GLOBAL OTHER SUGAR ALCOHOL EXCIPIENT MARKET, THROUGH 2018
($ MILLIONS/LBS MILLIONS) 55
Maltitol 55
Xylitol 55
Erythritol 56
Isomalt 56
Trehalose 56
Artificial Sweeteners 56
Market Size 56
TABLE 25 GLOBAL ARTIFICIAL SWEETENER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 57
Aspartame 57
Neotame 57
Acesulfame-K 57
Saccharin 58
Sucralose 58
Starches 58
Market Size 59
TABLE 26 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 59
TABLE 27 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 59
Dried Starch 59
Market Size 60
TABLE 28 GLOBAL DRIED STARCH EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 60
Modified Starch 60
Market Size 60
TABLE 29 GLOBAL MODIFIED STARCH EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 61
Converted Starch 61
Market Size 61
TABLE 30 GLOBAL CONVERTED STARCH EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 61
PETROCHEMICALS 61
Market Size 62
TABLE 31 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018
($ MILLIONS) 62
TABLE 32 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 62
Glycols 62
Market Size 63
TABLE 33 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 63
TABLE 34 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 64
Polyethylene Glycol 64
Market Size 64
TABLE 35 GLOBAL PEG EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 64
Propylene Glycol 65
Market Size 65
TABLE 36 GLOBAL PG EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 65
Povidones 65
Market Size 66
TABLE 37 GLOBAL PVP EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 66
Mineral Hydrocarbons 66
Market Size 66
TABLE 38 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE,
THROUGH 2018 ($ MILLIONS) 67
TABLE 39 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE,
THROUGH 2018 (LBS MILLIONS) 67
Petrolatum 67
Market Size 67
TABLE 40 GLOBAL PETROLATUM EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 68
Mineral Waxes 68
Market Size 68
TABLE 41 GLOBAL MINERAL WAX EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 68
Mineral Oils 69
Market Size 69
TABLE 42 GLOBAL MINERAL OIL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 69
Acrylic Polymers 69
Market Size 70
TABLE 43 GLOBAL ACRYLIC EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 70
Other Petrochemical Materials 70
Market Size 70
TABLE 44 GLOBAL OTHER PETROCHEMICAL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 71
Antimicrobials 71
Antioxidants 71
Dyes and Lakes 71
TABLE 45 SYNTHETIC COLORANTS IN PHARMACEUTICALS 72
EDTA 73
Flavors 73
Glycine and Glycylglycine 73
Vinyl Polymers 73
Silicones 73
Miscellaneous Synthetic Petrochemicals 74
OLEOCHEMICALS 74
Market Size 74
TABLE 46 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 75
TABLE 47 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 75
Fatty Alcohols 75
Market Size 75
TABLE 48 GLOBAL FATTY ALCOHOL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 75
Glycerin 76
Market Size 76
TABLE 49 GLOBAL GLYCERIN EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 76
Metal Stearates 77
Market Size 77
TABLE 50 GLOBAL METAL STEARATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 77
Other Oleochemicals 77
Market Size 78
TABLE 51 GLOBAL OTHER OLEOCHEMICAL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 78
Natural Waxes 78
Beeswax 78
Candelilla Wax 78
Carnauba Wax 78
Cocoa and Shea Butters 79
Lanolin 79
Phospholipids 79
Sodium Lauryl Sulfate 79
Sorbitan 79
Synthetic Glyceryl Esters 79
Vegetable Oils 80
PROTEINS 80
Gelatin 80
Market Size 81
TABLE 52 GLOBAL PROTEINS (GELATIN) EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 81
Albumin 81
OTHER ORGANIC CHEMICALS 81
TABLE 53 GLOBAL OTHER ORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH
2018 ($ MILLIONS/LBS MILLIONS) 82
Alcohols 82
Citric Acid 82
Lactic Acid 83
Polysaccharide Gums 83
Shellac 83
INORGANIC CHEMICALS 83
MARKET SIZE 83
TABLE 54 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH
2018 ($ MILLIONS) 84
TABLE 55 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH
2018 (LBS MILLIONS) 84
CALCIUM SALTS 84
Market Size 84
TABLE 56 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 85
TABLE 57 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 85
Calcium Phosphate 85
Market Size 86
TABLE 58 GLOBAL CALCIUM PHOSPHATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 86
Calcium Carbonate 86
Market Size 86
TABLE 59 GLOBAL CALCIUM CARBONATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 87
Calcium Sulfate 87
Market Size 87
TABLE 60 GLOBAL CALCIUM SULFATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 87
HALITES 88
Market Size 88
TABLE 61 GLOBAL HALITE EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 88
METAL OXIDES 88
Market Size 89
TABLE 62 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 89
TABLE 63 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 89
Titanium Dioxide 89
Market Size 90
TABLE 64 GLOBAL TIO2 EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 90
Iron Oxide 90
Market Size 90
TABLE 65 GLOBAL IRON OXIDE EXCIPIENT MARKET THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 91
SILICATES 91
Market Size 91
TABLE 66 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 91
TABLE 67 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 92
Silicon Dioxide 92
Market Size 92
TABLE 68 GLOBAL SILICON DIOXIDE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 92
Talc 93
Market Size 93
TABLE 69 GLOBAL TALC EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 93
Clay 93
Market Size 93
TABLE 70 GLOBAL CLAY EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 94
OTHER INORGANIC CHEMICALS 94
Market Size 94
TABLE 71 GLOBAL OTHER INORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH
2018 ($ MILLIONS/LBS MILLIONS) 94
USP WATER (PHARMACEUTICAL WATER) 95
MARKET SIZE 95
TABLE 72 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS) 96
TABLE 73 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2018 (LBS MILLIONS) 96
WATER FOR INJECTIONS 96
Market Size 96
TABLE 74 GLOBAL USP WFI EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 97
PURIFIED WATER 97
Market Size 97
TABLE 75 GLOBAL USP PURIFIED WATER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 97
FUNCTIONAL USES 98
TABLE 76 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH
2018 ($ MILLIONS) 98
TABLE 77 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH
2018 (LBS MILLIONS) 98
FILLERS 99
Market Size 99
TABLE 78 GLOBAL EXCIPIENT FILLER MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 99
TABLE 79 GLOBAL EXCIPIENT FILLER MARKET VOLUME BY TYPE, THROUGH 2018
(LBS MILLIONS) 100
EMOLLIENTS 100
Market Size 100
TABLE 80 GLOBAL EMOLLIENTS EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 100
VEHICLES 101
Market Size 101
TABLE 81 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 101
TABLE 82 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 101
COATINGS 102
Market Size 102
TABLE 83 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 103
TABLE 84 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 103
DISINTEGRANTS 104
Market Size 104
TABLE 85 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH
2018 ($ MILLIONS) 104
TABLE 86 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH
2018 (LBS MILLIONS) 105
FLAVORS 105
Market Size 105
TABLE 87 GLOBAL FLAVORS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2018
($ MILLIONS) 105
TABLE 88 GLOBAL FLAVORS EXCIPIENT MARKET VALUE BY TYPE, THROUGH 2018
(LBS MILLIONS) 106
TABLE 89 COMPARISON OF SEVERAL SWEETENERS TO SUCROSE (%) 106
COLORANTS 107
Market Size 107
TABLE 90 GLOBAL COLORANTS EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 107
TABLE 91 GLOBAL COLORANTS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH
2018 (LBS MILLIONS) 107
OTHER EXCIPIENT FUNCTIONS 108
Tonicity Agents 108
Market Size 108
Perfumes 108
Binders 109
Buffers 109
Chelating Agents 109
Compressions Aids 109
Emulsifiers 110
Foam Control Agents 110
Glidants 110
Humectants 110
Lubricants 110
Plasticizers 111
Preservatives 111
Thickeners 111
DELIVERY SYSTEMS 111
MARKET SIZE 112
TABLE 92 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET PERCENT SHARE BY
DOSAGE FORM, 2013 (%) 112
FIGURE 8 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET BY TYPE, PERCENT
VALUE 112
INJECTION 113
TABLE 93 TYPICAL INJECTION COMPOSITION (%) 113
Market Size 114
ORAL 115
Solids 115
Market Size 115
TABLE 94 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY
TYPE, 2013 ($ MILLIONS) 115
TABLE 95 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY
TYPE, 2013 (LBS MILLIONS) 116
Tablets 116
TABLE 96 TYPICAL TABLET COMPOSITION 116
Market Size 117
TABLE 97 GLOBAL EXCIPIENTS IN TABLETS MARKET BY FUNCTION, 2013 118
Capsules 119
Market Size 120
TABLE 98 EXCIPIENTS IN GELATIN CAPSULES, GLOBAL MARKET BY TYPE, 2013 ($
MILLIONS/%) 120
Hard Gelatin Capsules 120
TABLE 99 TYPICAL HARD GELATIN CAPSULE COMPOSITION 121
Market Size 121
TABLE 100 GLOBAL EXCIPIENTS IN HARD GELATIN CAPSULES MARKET VALUE BY
FUNCTION, 2013 (%) 121
Soft Gelatin Capsules 122
TABLE 101 TYPICAL SOFT GELATIN CAPSULE COMPOSITION 122
Market Size 122
TABLE 102 EXCIPIENTS IN SOFT GELATIN CAPSULES MARKET SHARE BY FUNCTION,
2013 ($ MILLIONS/LBS MILLIONS) 123
Liquids 123
TABLE 103 TYPICAL LIQUID COMPOSITION (%) 124
Market Size 124
TABLE 104 GLOBAL EXCIPIENTS IN LIQUIDS MARKET SHARE BY FUNCTION, 2013 ($
MILLIONS/LBS MILLIONS) 124
TOPICAL DELIVERY SYSTEMS 125
Market Size 125
TABLE 105 EXCIPIENTS IN TOPICAL DELIVERY SYSTEMS BY TYPE, 2013 ($
MILLIONS/LBS MILLIONS) 126
TABLE 106 TYPICAL OINTMENT COMPOSITION (%) 126
Creams and Gels 127
TABLE 107 TYPICAL CREAM COMPOSITION (%) 127
Lotions 128
TABLE 108 TYPICAL TOPICAL LOTION COMPOSITION (%) 128
Dermal Powders 128
Solutions 129
ADVANCED DELIVERY SYSTEMS 129
MARKET SIZE 129
CYCLODEXTRINS 129
HYDROGELS 129
IMPLANTS 129
LIPOSOMES 130
MICROPARTICLES 130
MICROSPHERES 130
NANOTECHNOLOGY (NANOPARTICLES) 130
OSMOTIC PUMPS 132
TRANSDERMAL 132
TRANSMUCOSAL 133
Buccal 133
Tablets 133
Capsules 134
Lozenges 134
Particles 134
Thin Strips 135
Inhalation 135
Nasal 135
Pulmonary 136
Ophthalmic 136
Otic 137
Rectal 137
Vaginal 138
FINISHED PRODUCTS 138
MARKET SIZE 138
TABLE 109 GLOBAL EXCIPIENTS IN FINISHED PRODUCTS BY TYPE, 2013 ($
MILLIONS/LBS MILLIONS) 139
PRESCRIPTION PRODUCTS 139
Market Size 139
Injections 140
Market Size 140
Small Molecule Drug Injections 140
Protein Drugs 140
Vaccines 141
Oral 142
Market Size 142
Topical 142
Advanced Drug Delivery Systems 142
OVER-THE-COUNTER PRODUCTS 143
Market Size 143
FINISHED PRODUCT TRENDS 143
Pharmacogenomics 144
Counterfeit/Stolen Drugs 144
INDUSTRY STRUCTURE 144
INDUSTRY ENVIRONMENT 145
MARKET INFLUENCES 145
Pharmaceutical Industry Pressures 145
General Health Trends 145
Healthcare Industry 146
Consumer Demographics 146
IMPORTANT STRATEGIES 146
RandD SPENDING 147
CONSUMER ADVERTISING 147
LEGISLATIVE LOBBYING 147
CONSOLIDATION 147
MULTIPLICITY OF DELIVERY SYSTEMS 147
SUPPLIER LISTS 147
MATERIAL CHOICE DECISIONS 148
DRIVING FORCES 148
MARKET SHARES 148
FIGURE 9 SIMPLIFIED INDUSTRY STRUCTURE 148
RAW MATERIAL SUPPLIERS 149
Organic Chemical Suppliers 149
Carbohydrate Suppliers 149
Cellulose Suppliers 150
FIGURE 10 MARKET SHARE OF MAJOR CELLULOSE SUPPLIERS, 2011 (%) 150
Sugar Suppliers 151
Actual Sugar Suppliers 151
FIGURE 11 MARKET SHARE OF ACTUAL SUGAR EXCIPIENT SUPPLIERS, 2011 (%) 151
Sugar Alcohols (Polyols) 152
FIGURE 12 MARKET SHARE OF MAJOR SUGAR ALCOHOL (POLYOL) EXCIPIENT
SUPPLIERS, 2011 (%) 152
Artificial Sweeteners 153
Starch Suppliers 153
FIGURE 13 MARKET SHARE OF MAJOR STARCH EXCIPIENT SUPPLIERS, 2011 (%) 153
Protein Suppliers 154
FIGURE 14 MARKET SHARE OF MAJOR PROTEIN (GELATIN) EXCIPIENT SUPPLIERS,
2011 (%) 154
Petrochemical Suppliers 155
Glycol Suppliers 155
FIGURE 15 MARKET SHARE OF MAJOR GLYCOL EXCIPIENT SUPPLIERS, 2011 (%) 155
PVP Suppliers 156
Mineral Hydrocarbon Suppliers 156
Acrylic Suppliers 156
Oleochemical Suppliers 156
FIGURE 16 MARKET SHARE OF MAJOR OLEOCHEMICAL EXCIPIENT SUPPLIERS, 2011
(%) 157
Inorganic Chemical Suppliers 158
Calcium Salts Suppliers 158
FIGURE 17 MARKET SHARE OF MAJOR CALCIUM-BASED EXCIPIENT SUPPLIERS,
2011 (%) 158
Halite Suppliers 159
FIGURE 18 MARKET SHARE OF MAJOR HALITE EXCIPIENT SUPPLIERS, 2011 (%) 159
Metal Oxide Suppliers 160
FIGURE 19 MARKET SHARE OF MAJOR METAL OXIDE EXCIPIENT SUPPLIERS, 2011
(%) 160
Silicate Suppliers 161
USP Water Suppliers 161
FIGURE 20 MARKET SHARE OF MAJOR USP WATER SUPPLIERS, 2011 (%) 161
DISTRIBUTORS/MODIFIERS 162
Distributors 163
TABLE 110 DISTRIBUTOR CATEGORIES 163
Brokers 163
Import/Export Traders 164
Chemical Stocking/Repacking 164
Modifiers 164
TABLE 111 CATEGORIES OF MODIFIERS 164
Contract Development Organizations 165
Contract Coaters 165
END USERS 165
TABLE 112 CATEGORIES OF END USERS 165
Drug Companies 165
Contract Formulators 166
Retail and Hospital Pharmacies 166
Pharmacy Colleges and Other Academic Institutions 166
Other End Users 167
INTERNATIONAL ASPECTS 167
Americas 167
Europe 167
Asia/Pacific Rim 168
Others 168

CHAPTER 6 COMPANY PROFILES 171

ABBOTT LABORATORIES 172
ADM (ARCHER DANIELS MIDLAND CO.) 172
AKZO NOBEL N.V. (ALSO ICI AND NATIONAL STARCH) 173
AMERICHEM PHARMACEUTICAL CORP. 174
AMTEX (QUIMICA AMTEX MEXICO) 174
ARLA FOODS A.M.B.A. 175
ASAHI KASEI CORP. (ASAHI KASEI PHARMA) 175
ASHLAND AQUALON FUNCTIONAL INGREDIENTS (AAFI) 176
ASSOCIATED BRITISH FOODS (ABF) 177
BANNER PHARMACAPS, INC. 177
BASF A.G. 178
BAXTER INTERNATIONAL, INC. 180
BLANVER FARMOQUIMICA, LTDA. 181
BRENNTAG GROUP 181
BUDENHEIM 182
CABOT CORP. 182
CALUMET SPECIALTY PRODUCTS PARTNERS, LP (PENRECO) 183
CARGILL, INC. 183
CHARLES TENNANT and COMPANY (CANADA) LTD. 184
COGNIS GMBH 185
COLORCON, INC. 185
CORBION 187
COSMETIC SPECIALTIES, INC. 187
CRISTAL GLOBAL (NATIONAL TITANIUM DIOXIDE CO., LTD.) 188
CRODA INTERNATIONAL, PLC 188
CSL BEHRING, LLC 189
CTD, INC. 190
CYDEX PHARMACEUTICALS, INC. 190
DANISCO A/S 191
DOW CHEMICAL CO. 192
DUPONT (E.I. DU PONT DE NEMOURS and CO.) 193
EASTMAN CHEMICAL CO. 194
EVONIK DEGUSSA GMBH (EVONIK INDUSTRIES AG) 195
FERRO CORP. 196
FIBROGEN, INC. 196
FLAVORX INC. 197
FMC CORP. 197
FOREMOST FARMS USA 199
FUJI HEALTH SCIENCE, INC. (FUJI CHEMICAL INDUSTRY CO., LTD.) 200
GATTEFOSSE GROUP 200
GE HEALTHCARE 201
GELITA AG 201
GENERAL CHEMICAL (GENCHEM) 202
GRAIN PROCESSING CORP. 202
GRIFOLS S.A. (LABORATORIOS GRIFOLS S.A.) 203
GTC BIOTHERAPEUTICS, INC. 203
HILMAR CHEESE CO. (HILMAR INGREDIENTS) 204
IMERYS 204
INGREDION INCORPORATED 205
INNOPHOS, INC. 205
INTERNATIONAL SPECIALTY PRODUCTS (ISP) 206
J.M. HUBER CORP. (CP KELCO AND HUBER ENGINEERED MATERIALS) 207
CP KELCO 207
HUBER ENGINEERED MATERIALS 207
JOST CHEMICAL CO. 208
JRS PHARMA (AND J. RETTENMAIER) 208
KOSTER KEUNEN HOLLAND B.V. 210
KRAFT FOODS ATLANTIC GELATIN 210
KRONOS WORLDWIDE, INC. 210
LANXESS A.G. 211
LUBRIZOL CORP. 211
LYONDELLBASELL INDUSTRIES 211
AVANTOR PERFORMANCE MATERIALS 212
MEGGLE GMBH 213
MERCK KGAA (AND EMD) 213
MINERALS TECHNOLOGIES, INC. (SPECIALTY MINERALS, INC.) 214
MINGTAI CHEMICAL CO., LTD. 215
MITSUBISHI CHEMICAL PERFORMANCE POLYMERS, INC. 216
MUTCHLER, INC. PHARMACEUTICAL INGREDIENTS 216
NITTA GELATIN, INC. 216
NORDZUCKER AG 217
NOVOZYMES A/S 217
NUSIL TECHNOLOGY 218
NUTRASWEET CO. 218
OMYA A.G. 219
PERRIGO CO. 219
PandG CHEMICALS 220
PMC GLOBAL, INC. 220
PURDUE PHARMA, LP 221
R.T. VANDERBILT COMPANY, INC. 221
RIO TINTO, PLC 222
ROQUETTE FRERES 222
ROUSSELOT S.A.S. 223
ROYAL FRIESLANDCAMPINA N.V. 224
SASOL, LTD. ADR 224
SENSIENT TECHNOLOGIES CORP. 225
SEPPIC S.A. 225
SHEFFIELD PHARMA INGREDIENTS 226
SHELL CHEMICALS (ROYAL DUTCH SHELL) 227
SHIN-ETSU CHEMICAL CO., LTD. 227
SOLVAY RHODIA S.A. 228
SOLVAY S.A. 229
SPI PHARMA, INC. 229
STEPAN CO. 230
STERLING BIOTECH, LTD. 230
TAKEHARA CHEMICAL INDUSTRIAL CO., LTD. 231
TALECRIS BIOTHERAPEUTICS, INC. 231
TATE and LYLE, PLC 231
TESSENDERLO GROUP (PB GELATINS) 232
TOMITA PHARMACEUTICAL CO., LTD. 232
USG CORP. 233
VERTELLUS PERFORMANCE MATERIALS, INC. (VPMI) 233
W.R. GRACE and CO. 233
WACKER FINE CHEMICALS (WACKER CHEMIE) 234
WEI MING PHARMACEUTICAL MFG. CO., LTD. 234
WEISHARDT GROUP 235



LIST OF TABLES

SUMMARY TABLE GLOBAL EXCIPIENT MARKET BY MATERIAL TYPE, THROUGH 2018
($ MILLIONS) 6
TABLE 1 GLOBAL EXCIPIENT MARKET VALUE BY MATERIAL TYPE, THROUGH 2018 ($
MILLIONS) 41
TABLE 2 GLOBAL EXCIPIENT MARKET VOLUME BY MATERIAL TYPE, THROUGH 2018
(LBS MILLIONS) 41
TABLE 3 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VALUE BY TYPE,
THROUGH 2018 ($ MILLIONS) 42
TABLE 4 GLOBAL ORGANIC CHEMICAL EXCIPIENT MARKET VOLUME BY TYPE,
THROUGH 2018 (LBS MILLIONS) 42
TABLE 5 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 43
TABLE 6 GLOBAL CARBOHYDRATE EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 43
TABLE 7 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 44
TABLE 8 GLOBAL CELLULOSE EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 44
TABLE 9 GLOBAL MCC EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 45
TABLE 10 GLOBAL CELLULOSE ETHER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 46
TABLE 11 GLOBAL CELLULOSE ESTER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 47
TABLE 12 GLOBAL CMC AND CROSCARMELLOSE EXCIPIENT MARKET, THROUGH
2018 ($ MILLIONS/LBS MILLIONS) 48
TABLE 13 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($ MILLIONS) 48
TABLE 14 GLOBAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018 (MILLION
LBS) 49
TABLE 15 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 50
TABLE 16 GLOBAL ACTUAL SUGAR EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 50
TABLE 17 GLOBAL LACTOSE EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 51
TABLE 18 GLOBAL SUCROSE EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 52
TABLE 19 GLOBAL DEXTROSE (GLUCOSE) EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 52
TABLE 20 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE,
THROUGH 2018 ($ MILLIONS) 53
TABLE 21 GLOBAL SUGAR ALCOHOL (POLYOL) EXCIPIENT MARKET BY TYPE,
THROUGH 2018 (LBS MILLIONS) 53
TABLE 22 GLOBAL SORBITOL EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 54
TABLE 23 GLOBAL MANNITOL EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 55
TABLE 24 GLOBAL OTHER SUGAR ALCOHOL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 55
TABLE 25 GLOBAL ARTIFICIAL SWEETENER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 57
TABLE 26 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 59
TABLE 27 GLOBAL STARCHES EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 59
TABLE 28 GLOBAL DRIED STARCH EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 60
TABLE 29 GLOBAL MODIFIED STARCH EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 61
TABLE 30 GLOBAL CONVERTED STARCH EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 61
TABLE 31 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 62
TABLE 32 GLOBAL PETROCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 62
TABLE 33 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 63
TABLE 34 GLOBAL GLYCOL EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 64
TABLE 35 GLOBAL PEG EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 64
TABLE 36 GLOBAL PG EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 65
TABLE 37 GLOBAL PVP EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 66
TABLE 38 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE, THROUGH
2018 ($ MILLIONS) 67
TABLE 39 GLOBAL MINERAL HYDROCARBON EXCIPIENT MARKET BY TYPE, THROUGH
2018 (LBS MILLIONS) 67
TABLE 40 GLOBAL PETROLATUM EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 68
TABLE 41 GLOBAL MINERAL WAX EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 68
TABLE 42 GLOBAL MINERAL OIL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 69
TABLE 43 GLOBAL ACRYLIC EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 70
TABLE 44 GLOBAL OTHER PETROCHEMICAL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 71
TABLE 45 SYNTHETIC COLORANTS IN PHARMACEUTICALS 72
TABLE 46 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 75
TABLE 47 GLOBAL OLEOCHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 75
TABLE 48 GLOBAL FATTY ALCOHOL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 75
TABLE 49 GLOBAL GLYCERIN EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 76
TABLE 50 GLOBAL METAL STEARATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 77
TABLE 51 GLOBAL OTHER OLEOCHEMICAL EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 78
TABLE 52 GLOBAL PROTEINS (GELATIN) EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 81
TABLE 53 GLOBAL OTHER ORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH 2018
($ MILLIONS/LBS MILLIONS) 82
TABLE 54 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH
2018 ($ MILLIONS) 84
TABLE 55 GLOBAL INORGANIC CHEMICAL EXCIPIENT MARKET BY TYPE, THROUGH
2018 (LBS MILLIONS) 84
TABLE 56 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 85
TABLE 57 GLOBAL CALCIUM SALT EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 85
TABLE 58 GLOBAL CALCIUM PHOSPHATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 86
TABLE 59 GLOBAL CALCIUM CARBONATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 87
TABLE 60 GLOBAL CALCIUM SULFATE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 87
TABLE 61 GLOBAL HALITE EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 88
TABLE 62 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 89
TABLE 63 GLOBAL METAL OXIDE EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 89
TABLE 64 GLOBAL TIO2 EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 90
TABLE 65 GLOBAL IRON OXIDE EXCIPIENT MARKET THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 91
TABLE 66 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 91
TABLE 67 GLOBAL SILICATES EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 92
TABLE 68 GLOBAL SILICON DIOXIDE EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 92
TABLE 69 GLOBAL TALC EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 93
TABLE 70 GLOBAL CLAY EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 94
TABLE 71 GLOBAL OTHER INORGANIC CHEMICAL EXCIPIENT MARKET, THROUGH
2018 ($ MILLIONS/LBS MILLIONS) 94
TABLE 72 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS) 96
TABLE 73 GLOBAL USP WATER EXCIPIENT MARKET, THROUGH 2018 (LBS MILLIONS) 96
TABLE 74 GLOBAL USP WFI EXCIPIENT MARKET, THROUGH 2018 ($ MILLIONS/LBS
MILLIONS) 97
TABLE 75 GLOBAL USP PURIFIED WATER EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 97
TABLE 76 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH 2018
($ MILLIONS) 98
TABLE 77 GLOBAL EXCIPIENT FUNCTIONAL USES MARKET BY TYPE, THROUGH 2018
(LBS MILLIONS) 98
TABLE 78 GLOBAL EXCIPIENT FILLER MARKET BY TYPE, THROUGH 2018 ($ MILLIONS) 99
TABLE 79 GLOBAL EXCIPIENT FILLER MARKET VOLUME BY TYPE, THROUGH 2018
(LBS MILLIONS) 100
TABLE 80 GLOBAL EMOLLIENTS EXCIPIENT MARKET, THROUGH 2018 ($
MILLIONS/LBS MILLIONS) 100
TABLE 81 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 101
TABLE 82 GLOBAL VEHICLE EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 101
TABLE 83 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 103
TABLE 84 GLOBAL COATINGS EXCIPIENT MARKET BY TYPE, THROUGH 2018 (LBS
MILLIONS) 103
TABLE 85 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH
2018 ($ MILLIONS) 104
TABLE 86 GLOBAL SUPERDISINTEGRANT EXCIPIENT MARKET BY TYPE, THROUGH
2018 (LBS MILLIONS) 105
TABLE 87 GLOBAL FLAVORS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH 2018
($ MILLIONS) 105
TABLE 88 GLOBAL FLAVORS EXCIPIENT MARKET VALUE BY TYPE, THROUGH 2018
(LBS MILLIONS) 106
TABLE 89 COMPARISON OF SEVERAL SWEETENERS TO SUCROSE (%) 106
TABLE 90 GLOBAL COLORANTS EXCIPIENT MARKET BY TYPE, THROUGH 2018 ($
MILLIONS) 107
TABLE 91 GLOBAL COLORANTS EXCIPIENT MARKET VOLUME BY TYPE, THROUGH
2018 (LBS MILLIONS) 107
TABLE 92 GLOBAL EXCIPIENT DELIVERY SYSTEMS MARKET PERCENT SHARE BY
DOSAGE FORM, 2013 (%) 112
TABLE 93 TYPICAL INJECTION COMPOSITION (%) 113
TABLE 94 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY TYPE,
2013 ($ MILLIONS) 115
TABLE 95 GLOBAL EXCIPIENTS IN ORAL SOLID DELIVERY SYSTEMS MARKET BY TYPE,
2013 (LBS MILLIONS) 116
TABLE 96 TYPICAL TABLET COMPOSITION 116
TABLE 97 GLOBAL EXCIPIENTS IN TABLETS MARKET BY FUNCTION, 2013 118
TABLE 98 EXCIPIENTS IN GELATIN CAPSULES, GLOBAL MARKET BY TYPE, 2013 ($
MILLIONS/%) 120
TABLE 99 TYPICAL HARD GELATIN CAPSULE COMPOSITION 121
TABLE 100 GLOBAL EXCIPIENTS IN HARD GELATIN CAPSULES MARKET VALUE BY
FUNCTION, 2013 (%) 121
TABLE 101 TYPICAL SOFT GELATIN CAPSULE COMPOSITION 122
TABLE 102 EXCIPIENTS IN SOFT GELATIN CAPSULES MARKET SHARE BY FUNCTION,
2013 ($ MILLIONS/LBS MILLIONS) 123
TABLE 103 TYPICAL LIQUID COMPOSITION (%) 124
TABLE 104 GLOBAL EXCIPIENTS IN LIQUIDS MARKET SHARE BY FUNCTION, 2013 ($
MILLIONS/LBS MILLIONS) 124
TABLE 105 EXCIPIENTS IN TOPICAL DELIVERY SYSTEMS BY TYPE, 2013 ($
MILLIONS/LBS MILLIONS) 126
TABLE 106 TYPICAL OINTMENT COMPOSITION (%) 126
TABLE 107 TYPICAL CREAM COMPOSITION (%) 127
TABLE 108 TYPICAL TOPICAL LOTION COMPOSITION (%) 128
TABLE 109 GLOBAL EXCIPIENTS IN FINISHED PRODUCTS BY TYPE, 2013 ($
MILLIONS/LBS MILLIONS) 139
TABLE 110 DISTRIBUTOR CATEGORIES 163
TABLE 111 CATEGORIES OF MODIFIERS 164
TABLE 112 CATEGORIES OF END USERS 165



LIST OF FIGURES

SUMMARY FIGURE GLOBAL EXCIPIENT MARKET, 2011-2018 ($ MILLIONS) 6
FIGURE 1 GLOBAL EXCIPIENT MARKET SHARE BY CATEGORY OF M

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