World Biotechnology Market Brief
The global outlook series on Biotechnology provides a collection of statistical anecdotes, market briefs, and concise summaries of research findings. The report offers a bird’s eye view of the Biotechnology industry. Annotated with 26 fact, and data rich tables presenting analytical segmentation by product application, the report provides global revenues, and expenditure on R&D of/by biotechnology companies, sales of enabling technologies, biologic drug sales by product and global biotech/pharmacogenomics/bioinformatics product/technology sales, among others. The report offers a sneak peek into major end-use industries, taking note of select trends in Genomics, Biochips, Biologics and Biopharmaceutical Intermediates, Biogenerics, Biotechnology Instruments, and Biotechnology Reagents, among others. Also included is a compilation of all recent mergers, acquisitions, and strategic corporate developments. A regional-level of discussion mirrors the prevalent scenario in key regional markets such as the US, Canada, Mexico, Japan, France, Germany, Poland, UK, Sweden, Switzerland, New Zealand, India, Malaysia, and Brazil, among few others. The report also includes an indexed, easy-to-refer, fact-finder directory listing the addresses, and contact details of 2,220 companies worldwide.
BIOTECHNOLOGY GOS-093
A GLOBAL OUTLOOK, SEPTEMBER 2008
CONTENTS
1. Biotechnology 1
Global Market Overview 1
Major companies 3
Table 1: Global Biotechnology Market by Product Application
- Antibiotics, Intermediates/ Biopharmaceuticals, Food/Feed,
Industrial Enzymes, Environmental Applications, Biodegradable
Polymers, and Agrochemical Markets Independently Analyzed
with Annual Sales Figures in US$ Billion for Years 2003
through 2008 4
Table 2: Global Biotechnology Market (2004 & 2008):
Percentage Breakdown of Value Sales by Product Application -
Antibiotics, Intermediates/ Biopharmaceuticals, Food/Feed,
Industrial Enzymes, Environmental Applications, Biodegradable
Polymers, and Agrochemical 4
Table 3: Leading Players in the Global Biotechnology Market
(2005 & 2006): Revenues in US$ Million for Amgen, Genentech,
Genzyme, UCB SA, Gilead Sciences, Serono, Biogen Idec, CSL,
Cephalon, MedImmune, Celgene, Abraxis BioScience, Actelion,
ImClone Systems, Elan, Amylin Pharmaceuticals, Millennium
Pharmaceuticals, PDL BioPharma, OSI Pharmaceuticals, and MGI
Pharma 5
Table 4: Leading Players in the Global Biotechnology Market
(2003): Expenditure on Research and Development in US$
Million for Amgen, Genentech, Biogen Idec, Serono, Genzyme,
Chiron, MedImmune, Cephalon, Millennium Pharmaceuticals,
Gilead Sciences, and Others 6
Table 5: Global Biotechnology Market by Category: Enabling
Technologies and Star Products Independently Analyzed with
Annual Sales Figures in US$ Billion for Years 2003 through
2008 6
Table 6: Global Biotechnology Market: Revenues in US$ Billion
for Years 2003 through 2008 7
Table 7: Leading Products in the Global Biotechnology Market
(2007): Sales in US$ Million for Aranesp, Enbrel, Remicade,
Erypo/Procrit, Neulasta, MabThera/Rituxan, Epogen, Herceptin,
Avastin, and Humira 7
Market for “Follow-On” Biologics 8
Market for Marine Biotechnology 8
Major Trends 8
Business Deals Involving Collaborations, Acquisition and
Joint Ventures to Drive Up Biotech Sales 8
Biotech Acquisitions Getting More Focused 9
Contract Manufacturing - A New Business Motto for
Biotechnology Companies 9
Oncology Dominates Biotech Drugs Sale 9
Investment on Research: Vital for the Survival of Biotech
Companies 10
Asia-Pacific: A Promising Market for Biopharmaceutical Companies 10
Biotech Regenerative Medicine Catching On 10
Reverse Merger Transactions Characterizes the Asian Biotech
Sector 10
Biotech Instrumentation to Speed Up Biotech Research Process 10
Growth of Bioventure Startups in Japan 10
Advent of “Mid-Tier” Companies in the Biotech Market 11
Biogenerics Poised for a Big Entry 11
Development of DNA Vaccines 11
The Development of Nano-Sized Delivery Systems Poses Problem
in the Biotech Sector 11
Issues Related to Pricing and Reimbursement of Biotech Drugs 11
End-Use Industries 11
Overview of Agricultural and Food Biotechnology 11
Plants Based Drugs - Innovative Agri Biotech Products 12
Consolidated Trends 12
Outlook of Health and Medical Biotechnology 12
Biotech Technologies/Fields of Medical & Health Sector 13
Bioinformatics 13
Table 8: Global Bioinformatics Technology Market: Revenues
in US$ Million for Years 2003 through 2008 13
Market Players 13
Genomics 13
Market Trends 14
Influencing Factors 14
Growth Driving Factors 14
Novel Business Area 14
Table 9: Leading Players in the Global Genomics Market
(2005): Revenues in US$ Million for Millennium
Pharmaceuticals, Myriad Genetics, Lexicon Genetics,
Celera Genomics, CuraGen, Human Genome Sciences, Maxygen,
and Incyte 14
Market Players 15
Pharmacogenomics 15
Overview 15
Table 10: Global Pharmacogenomics’ Market by Type:
Cardiovascular Disease, Infectious Disease, Central
Nervous System, Cancer, and Others Independently
Analyzed with Annual Sales Figures in US$ Million for
Years 2003 through 2008 15
Table 11: Global Pharmacogenomics’ Market (2004):
Percentage Breakdown of Value Sales for Cardiovascular
Disease, Infectious Disease, Central Nervous System,
Cancer, and Others 16
Biochips 16
Overview of the Biochip Industry 16
Biochip Technology 16
Building Bio Chips 16
Inexpensive Testing 16
Motorola, First Biochip Manufacturer 16
Tech Giants Join the Biochip Fray 17
Table 12: Global Biochip Market by Chip Type: DNA Chips
and Protein Chips Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2003 through 2008 17
Biologic Drugs 17
Market Overview 17
Major Drugs 17
Table 13: Leading Categories in the Global Biologic Drug
Market (2005): Sales in US$ Billion for Erythropoietins
(Aranesp, Procrit, Eprex, Epogen, Neo-Recormon), TNF
(Enbrel, Remicade, Humira), Major Cancer Antibodies
(Rituxan/MabThera, Herceptin, Avastin, Erbitux),
Interferon Beta (Avonex, Rebif, Betaferon/Betaseron), G-
CSF (Neulasta, Neupogen, Neutrogin), Rec. Coagulation
Factors (Novoseven, Kogenate, Refacto, Benefix),
Interferon Alpha (Pegasys, Pegintron, Intron A), Enzyme
Replacement (Cerezyme, Fabrazyme, Aldurazyme), Antiviral
Antibody (Synagis) and Follicle Stimulating Hormones
(Gonal-F, Puregon) 18
Biopharmaceutical and Small Drug Discovery 18
Market Overview 18
Role of Key Players 19
Market Players 19
Biologics and Biopharmaceutical Intermediates 19
Market Trends 19
Driving Factors 19
Biological Technologies and Services (A Historic Review) 19
Research and Development Expenditure 19
Biopharmaceutical Companies 19
Table 14: Global Biologics or Biopharmaceutical
Intermediates Market by Leading Technologies and
Services - Microbial Fermentation, Mammalian Cell
Culture, Biopharmaceutical Fill and Finish, Transgenics,
and Other Manufacturing Services Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 20
Table 15: Global Biologics or Biopharmaceutical
Intermediates Market (2004 & 2008): Percentage Breakdown
of Value Sales for Microbial Fermentation, Mammalian Cell
Culture, Biopharmaceutical Fill and Finish, Transgenics,
and Other Manufacturing Services 20
Table 16: Global Biopharmaceutical Market (2003):
Research and Development Expenditures in US$ Million
for Pfizer, Johnson & Johnson, GlaxoSmithKline, Sanofi-
Aventis Group, Novartis, Roche, Merck, AstraZeneca, Eli
Lilly, Wyeth, and Others 21
Cell and Tissue Culture 21
Market Overview 21
Market Trends 21
Surging Demand for Cell Culture Products 21
Proteomics and Pharmacokinetics Drive Market Growth 22
Regulations Prompt Change in Trends 22
Biotechnology Instruments 22
Market Overview 22
Growth Trends 22
Biotechnology - Major Impact on Analytical Instruments
Market 22
Innovations and Discoveries - Fuel Demand for Biotech
Instrumentation 22
Technological Developments Influence Market Growth 23
Market Players 23
Biotechnology Reagents 23
Market Overview 23
Market Trends 23
Highly Automated Instrumentation Restricts Use of Reagents 23
Molecular Biology and Protein Synthesis Reagents are
Growing Rapidly 23
Environmental and Industrial Biotechnology 23
Nanophase Technologies Corp., (NTC) in BioTechnology 23
2. Mergers and Acquisitions 25
3. Strategic Corporate Developments 59
4. Product Launches & Developments 84
A REGIONAL MARKET PERSPECTIVE
1. North America 86
1a. The United States 86
Overview 86
Table 17: Leading Players in the US Biotechnology Market
(2006): Sales in US$ Million for Amgen, Roche (Genentech),
Johnson & Johnson, Lilly, Novo Nordisk, Sanofi-Aventis,
Abbott, Biogen Idec, Serono, and Medimmune 86
Table 18: Leading Products in the US Biotechnology Market
(2006): Sales in US$ Million for Aranesp, Epogen, Enbrei,
Neulast, Procrit, Remicade, Rituxan, Avastin, Lantus, and
Herceptin 87
Table 19: Biotechnology Market in the US: Percentage
Breakdown of Value Product Sales by Sector - Therapeutics,
Diagnostics, Agriculture, Chemicals and Others 87
Agricultural Biotechnology 87
Market Overview 87
Market Trends 87
Success Stories and Demand 87
Table 20: Agricultural Biotech Market in the US by Product
Segment - Transgenic Seeds/Crops (Soybean, Corn, Cotton,
Others), and Biopesticides Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2003 through
2008 88
Table 21: Agricultural Biotech Market in the US (2004 &
2008): Percentage Breakdown of Value Sales for Transgenic
Seeds/Crops (Soybean, Corn, Cotton and Others), and
Biopesticides 88
Market Players 88
Medical Biotechnology - Market Overview 88
Eye on different fields of Medical Biotech 89
Bioinformatics 89
Regulatory Environment 89
Proteomics 89
Biochips 89
Patient Applications 89
1b. Canada 90
Market Overview 90
Facts of Canadian Biotechnology Industry 90
Table 22: Biotechnology Market in Canada: Revenues in US$
Billion for Years 2004 through 2010 90
1c. Mexico 91
Biotechnology - Market Overview 91
End-Use Industries 91
Bio-Pharmaceuticals 91
Food Biotechnology 91
Environmental Biotechnology 91
2. Japan 91
Biotechnology Market Overview 91
End-Use Industries 92
Medical Biotechnology and Healthcare 92
Bioinformatics 92
Food Biotechnology Industry 92
Environmental Biotechnology 92
Bioremediation 92
Biodegradable Plastics 93
3. A European Market Perspective 93
Industry Overview 93
3a. Denmark 93
3b. France 94
Overview 94
3c. Germany 94
Overview 94
3d. Italy 95
Overview 95
3e. Poland 95
Overview 95
Market Access Regulations 95
3f. United Kingdom 96
Medical Biotechnology and Healthcare Sector 96
Agricultural Biotechnology 96
3g. Sweden 96
Overview 96
3h. Switzerland 97
Overview 97
Table 23: Biotechnology Market in Switzerland (2005):
Percentage Breakdown of Value Sales by Sector - Engineering,
Therapeutics & Diagnostics, Technologies, Contract Research &
Manufacturing, Bioelectronics & Bioinformatics, Bio and
Specialty Chemicals, Environmental Technologies, Agricultural
and Food Processing Service Providers & Supporters 97
4. Asia-Pacific 98
Overview 98
4a. Australia 98
Overview 98
4b. New Zealand 98
Overview 98
Table 24: Biotechnology Market in New Zealand (2005):
Percentage Breakdown of Value Sales by Sector - Biotech
Suppliers & Service Providers, Human Therapeutics,
Agricultural Biotechnology, Chemical & Environmental Biotech,
Food & Beverages, Bioinformatics, Diagnostics, and Others 99
4c. China 99
4d. India 99
Market Overview 99
Booming Biotechnology Industry 100
Bio-pharma Drives Growth in Biotech Industry 101
Growth in Industry Sparks Investments 101
Transformation - Creating a Platform for Future Growth in
Biotech Industry 101
4e. Malaysia 102
Overview of Malaysian Biotechnology Industry 102
Role of National Biotechnology Directorate (Biotek) 102
Market Trends 102
4f. South Korea 103
Biotechnology Industry Overview 103
Table 25: Biotechnology Market in Korea (2004 & 2005):
Production in US$ Billion 103
4g. Taiwan 103
5. Other Markets 103
5a. Argentina 103
5b. Brazil 104
Industry Outlook 104
Table 26: Biotechnology Market in Brazil (2005): Percentage
Breakdown of Value Sales by Sector - Human Health,
Biotechnology Companies, Consumables Suppliers, Equipment,
Agribusiness, Animal Health, and Environment 104
End-Use Industries 104
Diagnostics 104
Biotechnology and Animal Health 104
Agricultural Biotechnology 104
Environmental Biotechnology 104
Biotechnology in Food Processing 105
5c. Israel 105
GLOBAL DIRECTORY
