Mass Spectrometry 2013 presents the findings of a global market study of mass spectrometry, involving the participation of 567 buyers and end-users in this field. With a focus on market development, sales growth and commercial opportunities, the study profiled current and evolving areas of this market, as outlined below. Its findings provide valuable product and market information, and decision-making support to suppliers in the mass spectrometry field.
The market for MS instrumentation has grown steadily over the past decade and in 2009 global sales and ancillary services are estimated at around $3.3 billion, and increasing at around 10% per year. This report, based on an analysis of key market areas in the mass spectrometry field, has been produced to provide business decision-making support to suppliers in this field, and to identity new opportunities. It is the outcome of an extensive global study of MS end-users and managers and its findings provide a focus on sales growth and the changes that are driving these developments. The following indicate the key market areas covered in the study:
• Companies: Purchases of MS instruments and related systems from MS companies and anticipated purchases from specific mass spectrometry companies over the next three years, ranked according to prominence.
• Ionisation Methods: Current use of more than 30 ionisation methods and the anticipated use of ionisation methods over the next three years, ranked according to prominence.
• Ion Analysers: Current use of more than 30 ion analysers and the anticipated use of ion analysers over the next three years, ranked according to prominence.
• MS Configurations: Current use of more than 100 MS configurations and the anticipated use of MS configurations over the next three years, ranked according to prominence.
• Fragmentation Methods: Current use of more than 20 fragmentation methods and the anticipated use of fragmentation methods over the next three years, ranked according to prominence.
• Innovation: Greatest areas of innovation in the MS field that are anticipated over the next three years relating to ionisation methods, ion analysers, detection methods, data systems/specialist software, sample preparation and other areas; most needed areas of innovation in the MS field over the next three years relating to ionisation methods, ion analysers, detection methods, data systems/specialist software, sample preparation and other areas; most important innovations in the mass spectrometry field over the last three years and the most important emerging applications in the MS field, over the next three years.
• Challenging Applications: Disclosures on 250+ analyte molecule types that present particular challenges or problems to MS analysis, ranked according to prominence; 115+ sample matrices associated with samples that present particular problems to MS analysis, ranked according to prominence; ionisation methods, ion analysers, MS configurations, fragmentation methods and sample preparation techniques that are used for molecule types that present particular challenges to mass spectrometric analysis, ranked according to prominence and underlying reasons associated with their most challenging mass spectrometry applications, grouped and ranked according to prominence.
• Expenditure: Average hourly, daily and annual running costs per MS system; average annual budgets relating to the use of mass spectrometry; the breakdown of financial budgets relating to MS instruments, sample preparation instruments, consumables, data handling/specialist software and other areas; anticipated budgets over the next three years and the top three consumables in the MS field, in terms of cost.
• Data Systems: Current use of integrated data systems (supplied with the MS systems purchased) or alternatively, the use of independent data systems; current use of more than 30 independent data systems, ranked according to their level of use; current use of more than 80 database software systems, ranked according to their level of use and the use of database software over the next three years, ranked according to their anticipated level of use.
• Mass Spectrometry Activities: Time expenditure on the part of MS users, relating to data handling, sample preparation and mass spectrometric analysis.
• Participant Fields: Biotechnology, chemicals, clinical, defence, energy, environmental, food and drink, forensics, geology, healthcare, natural products, pharmaceuticals, universities and research institutes.
• Purpose: Purpose or reason for carrying out mass spectrometry across 13 major fields previously indicated, profiled and ranked according to prominence.
• Study Samples: Study samples analysed across 13 fields previously indicated, each ranked according to prominence.
• Analyte Molecules: Analyte molecule classes analysed using MS across 13 fields previously indicated, each ranked according to prominence.
• Applications: MS applications across 13 fields previously indicated, each profiled and ranked according to prominence.
• Sample Preparation: Current use of sample preparation methods and the anticipated use of sample preparation methods over the next three years, ranked according to prominence.
• Quantitative vs. Qualitative: The percentage of current MS applications that are either quantitative, qualitative or both.
Software Industry
Executive Summary
1. Introduction p.15
2. Participants p.22
3. Mass Spectrometry Systems p.31
4. Ionisation Methods p.38
5. Ion Analyzers p.46
6. Data Systems p.60
7. MS Configurations p.66
8. Fragmentation p.72
9. Molecules p.79
10. Purpose p.86
11. Samples p.106
12. Applications p.125
13. Quantitative vs. Qualitative p.144
14. Sample Preparation p.152
15. Challenging Applications p.178
16. Future Use p.192
17. Innovation p.201
18. Mass Spectrometry Activities p.220
19. Expenditure p.231
20. Final Comments p.238
21. Discussion and Conclusions p.252
22. Appendices p.262
Figures
Figure 2.1 Countries of individuals participating in Mass Spectrometry 2012.
Figure 2.2 Global regions of individuals who participated in Mass Spectrometry 2012.
Figure 2.3 Organisation types of individuals who participated in Mass Spectrometry 2012.
Figure 2.4 Fields (i.e. sectors) of individuals who participated in Mass Spectrometry 2012.
Figure 3.1 Top ten currently used mass spectrometry companies and suppliers indicated by individuals who participated in Mass Spectrometry 2012.
Figure 4.1 Top ten currently used ionisation methods, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 5.1 Top ten currently used ion analyzers, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 6.1 Independent data systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 6.2 The top ten independent data systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 6.3 The top ten database software systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 6.4 The top ten other software systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 7.1 Top ten configurations currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 7.2 Top ten other configurations currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 8.1 Top ten fragmentation methods currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 8.2 Top ten other fragmentation methods currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 9.1 Top ten molecules currently analyzed using mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.1 Top ten purposes (or reasons) for using mass spectrometry in the biotechnology industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.2 Top ten purposes (or reasons) for using mass spectrometry in the chemical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.3 Top ten purposes (or reasons) for using mass spectrometry in the clinical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.4 Top ten purposes (or reasons) for using mass spectrometry in the defence industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.5 Top ten purposes (or reasons) for using mass spectrometry in the energy industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.6 Top ten purposes (or reasons) for using mass spectrometry in the environmental industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.7 Top ten purposes (or reasons) for using mass spectrometry in the food and drink industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.8 Top ten purposes (or reasons) for using mass spectrometry in the forensics industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.9 Top ten purposes (or reasons) for using mass spectrometry in the geology industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.10 Top ten purposes (or reasons) for using mass spectrometry in the healthcare industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.11 Top ten purposes (or reasons) for using mass spectrometry in the natural products industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.12 Top ten purposes (or reasons) for using mass spectrometry in the pharmaceutical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 10.13 Top ten purposes (or reasons) for using mass spectrometry in universities and research institutes, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.1 Top ten sample types analysed using mass spectrometry in the biotechnology industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.2 Top ten sample types analysed using mass spectrometry in the chemical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.3 Top ten sample types analysed using mass spectrometry in the clinical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.4 Top ten sample types analysed using mass spectrometry in the defence industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.5 Top ten sample types analysed using mass spectrometry in the energy industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.6 Top ten sample types analysed using mass spectrometry in the environmental industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.7 Top ten sample types analysed using mass spectrometry in the food and drink industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.8 Top ten sample types analysed using mass spectrometry in the forensics industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.9 Top ten sample types analysed using mass spectrometry in the geology industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.10 Top ten sample types analysed using mass spectrometry in the healthcare industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.11 Top ten sample types analysed using mass spectrometry in the natural products industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.12 Top ten sample types analysed using mass spectrometry in the pharmaceutical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 11.13 Top ten sample types analysed using mass spectrometry in universities and research institutes, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.1 Top ten mass spectrometry applications used in the biotechnology industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.2 Top ten mass spectrometry applications used in the chemical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.3 Top ten mass spectrometry applications used in the clinical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.4 Top ten mass spectrometry applications used in the defence industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.5 Top ten mass spectrometry applications used in the energy industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.6 Top ten mass spectrometry applications used in the environmental industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.7 Top ten mass spectrometry applications used in the food and drink industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.8 Top ten mass spectrometry applications used in the forensics industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.9 Top ten mass spectrometry applications used in the geology industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.10 Top ten mass spectrometry applications used in the healthcare industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.11 Top ten mass spectrometry applications used in the natural products industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.12 Top ten mass spectrometry applications used in the pharmaceutical industry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 12.13 Top ten mass spectrometry applications used in universities and research institutes, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 13.1 The proportions (%) of individuals who use qualitative or quantitative applications in mass spectrometry, or both, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.1 Top ten sample preparation techniques currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.2 Top ten most challenging or difficult applications in mass spectrometry by molecule type, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.3 Top ten most challenging or difficult applications in mass spectrometry by sample matrix, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.4 Top ten ionisation methods used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.5 Top ten ion analyzers used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.6 Top ten configurations used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.7 Top ten fragmentations methods used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 14.8 Top ten sample preparation methods used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.1 The top ten mass spectrometry companies from which products will be purchased over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.2 The top ten ionisation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.3 The top ten ion analyzers that will be used over the next three years (2012 – 2-15), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.4 The top ten database/software systems that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.5 The top ten other specialist software systems that will be used over the next three years (2012 – 2-15), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.6 The top ten mass spectrometry configurations that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.7 The top ten mass spectrometry fragmentation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 16.8 The top sample preparation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 17.1 The areas of greatest innovation in mass spectrometry anticipated over the next three years, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 17.2 The areas of innovation that are most required in mass spectrometry over the next three years, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 17.3 Top ten most important innovations in mass spectrometry over the last three years, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 17.4 Top ten most important innovations in mass spectrometry that are anticipated over the next three years, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 17.5 Top ten emerging applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 18.1 The major time-consuming areas in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 18.2 A profile of the average run time (sample preparation + analysis + data handling) of samples in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 18.3 A profile of the average daily sample throughput in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 18.4 A profile of the average weekly sample throughput in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 18.5 A profile of the average annual sample throughput in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.1 A profile of the average mass spectrometry running costs per system per hour, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.2 A profile of the average mass spectrometry running costs per system per day, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.3 A profile of the average mass spectrometry running costs per system per year, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.4 A profile of the average annual financial budget for mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.5 A breakdown of the major areas of expenditure in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.6 Predicted changes in financial budgets for mass spectrometry over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 19.7 The top ten consumables used in mass spectrometry based on their cost, indicated by individuals who participated in Mass Spectrometry 2012.
Tables
Table 2.1 Countries of individuals who participated in Mass Spectrometry 2012.
Table 2.2 Global regions of individuals who participated in Mass Spectrometry 2012.
Table 2.3 Organisation types of individuals who participated in Mass Spectrometry 2012.
Table 3.1 Currently used mass spectrometry companies, indicated by individuals who participated in Mass Spectrometry 2012.
Table 3.2 Other currently used mass spectrometry companies, indicated by individuals who participated in Mass Spectrometry 2012.
Table 4.1 Currently used ionisation methods, indicated by individuals who participated in Mass Spectrometry 2012.
Table 4.2 Other currently used ionisation methods, indicated by individuals who participated in Mass Spectrometry 2012.
Table 5.1 Currently used ion analyzers, indicated by individuals who participated in Mass Spectrometry 2012.
Table 5.2 Other currently used ion analyzers, indicated by individuals who participated in Mass Spectrometry 2012.
Table 6.1 Independent data systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 6.2 Database software systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 6.3 Other software systems currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 7.1 Configurations currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 7.2 Other configurations currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 8.1 Fragmentation methods currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 8.2 Other fragmentation methods currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 9.1 Molecules currently analyzed using mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 9.2 Other molecules currently analyzed using mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 14.1 Sample preparation techniques currently used in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 14.1 Most challenging or difficult applications in mass spectrometry by molecule type, indicated by individuals who participated in Mass Spectrometry 2012.
Table 14.2 Most challenging or difficult applications in mass spectrometry by sample matrix, indicated by individuals who participated in Mass Spectrometry 2012.
Table 14.3 Sample preparation methods used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 14.4 Other sample preparation methods used in the most challenging or difficult applications in mass spectrometry, indicated by individuals who participated in Mass Spectrometry 2012.
Table 14.5 The most challenging methods in mass spectrometry, by molecule, matrix and challenge, indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.1 Mass spectrometry companies from which products will be purchased over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.2 Other spectrometry companies from which products and/or services will be purchased over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.3 Ionisation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.4 Other ionisation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.5 Ion analyzers that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.6 Other ion analyzers that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.7 Database/software systems that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.8 Other database/software systems that will be used over the next three years (2012 – 2-15), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.9 Other specialist software systems that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.10 Mass spectrometry configurations that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.11 Other mass spectrometry configurations that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.12 Mass spectrometry fragmentation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.13 Other mass spectrometry fragmentation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.14 Sample preparation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Table 16.15 Other sample preparation methods that will be used over the next three years (2012 – 2015), indicated by individuals who participated in Mass Spectrometry 2012.
Figure 17.2 The areas of innovation that are most required in mass spectrometry over the next three years, indicated by individuals who participated in Mass Spectrometry 2012.
Table 17.1 Most important innovations in mass spectrometry over the last three years, indicated by individuals who participated in Mass Spectrometry 2012.
Table 17.2 Most important innovations in mass spectrometry that are anticipated over the next three years, indicated by individuals who participated in Mass Spectrometry 2012.
Table 17.3 Emerging applications in mass spectrometry, as indicated by individuals who participated in Mass Spectrometry 2012.
Table 19.1 The top ten consumables used in mass spectrometry based on their cost, indicated by individuals who participated in Mass Spectrometry 2012.
