Global Intraocular Lenses Industry

• Publication date: March 2013
• Report size: 338 pages

This report analyzes the worldwide markets for Intraocular Lenses in US$ Million and Thousand Units by the following Product Segments: Standard Intraocular Lenses, and Premium Intraocular Lenses. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2010 through 2018. Also, a six-year historic analys...

This report analyzes the worldwide markets for Intraocular Lenses in US$ Million and Thousand Units by the following Product Segments: Standard Intraocular Lenses, and Premium Intraocular Lenses.

The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2010 through 2018. Also, a six-year historic analysis is provided for these markets.

The report profiles 36 companies including many key and niche players such as Aaren Scientific, Inc., Abbott Medical Optics, Inc., Alcon, Inc., Bausch & Lomb, Inc., Carl Zeiss Meditec AG, Hoya Corporation, OPHTEC BV, Rayner Intraocular Lenses Limited, STAAR Surgical Company, and The HumanOptics AG. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

Global Ophthalmic Devices Industry

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
Intraocular Lenses I-3
Standard Intraocular Lenses I-3
Premium Intraocular Lenses I-3
Toric Intraocular Lenses I-4
Other Premium Intraocular Lenses I-4
Premium Monofocal Lenses I-4
Multifocal IOLs I-4
Accommodative IOLs I-4


II. EXECUTIVE SUMMARY

1. OUTLOOK II-1
IOLs - Advancing Vision Care II-1
Table 1: Cataract Surgery Market Worldwide by Product Segment
(2012) - Percentage Share Breakdown of Revenues for
Intraocular Lenses (IOLs), Viscoelastics, Equipment,
Instruments and Others (includes corresponding Graph/Chart) II-2
Current & Future Analysis II-2
Developed Countries Dominate, While Emerging Markets Drive
Growth II-2
US - Leading the Way in the Global IOLs Market II-2
Premium Products Drive Revenue Growth II-3
Premium Lens Take the Brunt of Weaker Economic Environment II-4
Outlook II-4
Dramatic Growth in Aging Population to Fuel Growth II-5
Table 2: Percentage Share of Global Population by Age
Group: 2025 (includes corresponding Graph/Chart) II-5
Product -Level Market Dynamics II-5
Major Market Drivers and Restraints in a Gist II-6
Driving Factors II-6
Restraining Factors II-6

2. INDUSTRY OVERVIEW II-7
Intraocular Lenses: A Market Primer II-7
The Epic Transition from Non-foldable to Foldable Continues II-7
Cataract in Tandem with Old Age II-8
A Glimpse of Cataract Procedures Worldwide II-8
Table 3: Recent Past, Current and Future Analysis of Cataract
Procedures Worldwide Analyzed in terms of Number of
Procedures in Millions for Years 2010 through 2018 (includes
corresponding Graph/Chart) II-9

Table 4: Number of Cataract Procedures Carried Out Worldwide
by Country/Region (2012): Procedure Count in Thousands for
India, US, Europe, Japan, China, Brazil and Rest of World
(includes corresponding Graph/Chart) II-9
Where the Growth Lies II-10
Target Customer Groups & their Requirement Patterns II-10
Technological Innovations: A Boon to the IOL Industry II-10
Lasers: The High-Tech Solution II-11
Viscosurgery: A Safer Alternative II-11
Low Energy Methods for Cataract Removal II-11

3. TRENDS & ISSUES II-12
New Product Innovations in Accommodative IOLs Pep-Up the Market II-12
PC-IOLs: Raising the Standard II-12
Promising Pipeline for PC-IOLs II-12
Accommodative IOLs or Multifocal IOLS, the Tussle Carries On II-12
Post-operative Refractive Errors - A Concern for Premium IOLs II-13
Adjustable IOLs - Addressing Refractive Concerns of IOLs II-14
Debate Continues on Whether UV Protection is Essential in IOLs II-14
The Blue Light Saga II-14
US Lags Behind Europe in IOL Approvals II-15
US & Europe Divided on Choice of Phakic IOL Options II-15
Reimbursement Programs - The Key Determinant for Advanced IOLs II-16
IOL Reimbursement - A Comparison between the US and European
Systems II-16

4. COMPETITION II-17
A Peek into the Global IOL Competitive Landscape II-17
Table 5: Leading Players in the Global Cataract Intraocular
Lens Market (2012): Percentage Breakdown of Value Sales for
Alcon, Abbott Medical Optics, Bausch & Lomb, Hoya, Carl Zeiss
Meditec and Others (includes corresponding Graph/Chart) II-17
Alcon - The Global Leader in Cataract Surgery Devices II-17
AMO - Product Development and Global Expansion to Drive Sales II-18
STAAR Surgical - Eyeing an Increased Role in IOL Market II-18
Visian ICL Dominates Global Phakic IOLs Market II-19
Table 6: Leading Players in the Global Anterior Phakic IOL
Market (2012): Percentage Breakdown of Unit Sales for STAAR
Surgical, Ophtec and Novartis (includes corresponding
Graph/Chart) II-19

5. PRODUCT LANDSCAPE II-20
Multifocal IOLs II-20
Multifocal Lenses - Bridging Gap between Conventional and
Accommodative IOLs II-20
List of Select Approved and Under-Development Multifocal IOLs II-20
Overview of Select Multifocal IOLs II-20
ReZoom® (Abbott Medical Optics) II-20
ReSTOR® (Alcon) II-20
Tecnis® (Abbott Medical Optics) II-21
Tecnis Vs. ReSTOR II-21
A Comparison of Major Multifocal IOLs - ReSTOR, ReZoom
and Tecnis Multifocal II-21
AcrySof IQ ReSTOR IOL - Types II-22
Lentis MPlus (Oculentis) II-22
AT LISA (Carl Ziess Meditec) II-22
FineVision (PhysIOL) II-22
Accommodative Intraocular lenses II-23
Mechanisms in Accommodative IOL Creation II-23
Accommodative Lenses and Their Need II-24
List of Select Approved and Under-Development Accommodative
IOLs II-24
Overview of Select Accommodative IOLs II-25
Crystalens® (Bausch & Lomb) II-25
Crystalens - A Brief History II-25
Synchrony (AMO/Visiogen) II-25
The Need for a Suitable Injector II-26
Femtosecond Laser-Based Capsulorhexis - Further Increasing
Efficient of Synchrony II-26
Myriad Studies Acknowledge Synchrony’s Efficacy II-26
Tetraflex (Lenstec) II-26
Tetraflex - Awaiting FDA Nod in the US II-27
FluidVision Lens (PowerVision) II-27
Assessing the Strengths of FluidVision . II-28
DynaCurve (NuLens Ltd.) II-28
Concerns Drive Changes in Initial Product Design for
DynaCurve II-29
Near Vision - The Key Target for DynaCurve II-29
Tek-Clear IOL (Tekia) II-29
1CU Lens (HumanOptics AG) II-30
A Comparison of Major Accommodative IOLs - Crystalens,
Synchrony and Tetraflex II-30
Monofocal Lenses II-30
Monofocal IOLs - Fighting for Attention II-30
Monofocal Lenses - Advantages and Disadvantages II-31
Advantages II-31
Disadvantages II-31
Europe Takes the Front Seat in Monofocal IOLs II-31
Overview of Select Monofocal Lens II-31
EC-3 Lenses (Aaren Scientific) II-31
Clinical Data II-32
iSymm Lens (Hoya Optics) II-32
iSymm IOL II-32
iSert IOL II-32
Softec HD (Lenstec) II-33
Toric IOLs II-33
Toric Intraocular Lenses - Gaining Impetus II-33
Wide Range of Power and Improved Surgical Procedures Drive
Volumes of Toric Lenses II-34
List of Select Approved and Under-Development Toric IOLs II-34
Overview of Select Toric Lenses II-35
STAAR Toric IOL (STAARSurgical) II-35
Acri.Comfort and Acri.LISA Toric Lenses (Acri.Tec AG/Carl
Zeiss Meditec) II-35
MicroSil Toric IOL (HumanOptics) II-35
AcrySof Toric IOL (Alcon Laboratories Inc.) II-35
LENTIS Unico (Oculentis) II-36
Rayner T-flex Toric (Rayner) II-36
Phakic IOLs II-36
List of Select Approved and Under-Development Phakic IOLs II-36
A Comparison of Approved and Under-Development Phakic IOLs -
Verisyse/Artisan, Veriflex/Artiflex, Visian ICL and Cachet
IOL II-37
Potential Issues with Alcon’s Cachet IOL II-37
Veriflex - A Versatile Innovation II-37
Will the New Phakic IOLs be the Game Changer? II-37
Aspheric IOLs II-38
Aspheric Lenses Revolutionizing Vision II-38
List of Select Marketed Aspheric IOLs II-38
Overview of Select Aspheric Lenses II-39
aKromalens SeeLens AC (Hanita) II-39
nanoFLEX IOL (STAAR Surgical) II-39
Micro-Incision IOLs II-39
Available Products that Support MICS II-39
Acri.Smart Lens (Acri Tec GmbH, Germany) II-39
SlimFlex® (PhysIOL, Belgium) II-40
Idea’ Lens (Xcelens S.A, Switzerland) II-40
ThinOptX (ThinOptX, US) II-40
ELENZA’s Electronic IOL - a New Revolution in the Making II-40
Evolution of Lens Material II-41
Various Materials Used in IOLs & their Characteristics II-41
Rigid PMMA acrylic II-41
Foldable Acrylics II-42
Silicone Elastomers II-42
Major Differentiating Characteristics II-43
Refractive Index II-43
Glass Transition Temperature II-43
Water Content II-43
Postoperative Calcification II-43
Glisterings II-43

6. PRODUCT OVERVIEW II-44
Evolution of Intraocular Lenses II-44
Structure of IOL II-44
Types of IOLs II-44
Classification Based on Material Used II-44
PMMA II-45
Silicones II-45
Flexible Acrylic II-45
Hydrogels II-45
Polymer with Thermo Mechanical Properties II-45
Classification Based on In-Situ Location II-45
Anterior Chamber IOLs II-45
Iris-Clip Lens II-46
Posterior Chamber IOLs II-46
Classification Based on Focus II-46
Monofocal IOLs II-46
Standard Monofocal IOLs II-46
Premium Lenses II-47
Premium Monofocal Lenses II-47
Multifocal IOLs II-47
Types of Multifocal Lenses II-47
Accommodative IOLs II-47
Toric IOLs II-48
Phakic IOLs II-48
Types of Phakic IOLs II-48
A Comparison of Four Key IOL Types - Standard Monofocal
IOLs, Toric IOLs (Premium), Multifocal IOLs and
Accommodative IOLs II-49
The Formation of Cataract II-49
Astigmatism II-49
Presbyopia II-50
Cataract Extraction Procedures II-50
Intracapsular Cataract Extraction II-50
Extracapsular Cataract Extraction (ECCE) II-50
Phacoemulsification II-50
Post Cataract Extraction: The Alternatives II-50
Intraocular Lenses: A Much Better Solution II-51
A Retrospection II-51

7. EFFECTS OF INTRAOCULAR LENSES IMPLANTATIONS II-52
Changes in the Size of Capsulorhexis Following IOL Implantation II-52
Effect of Anterior Chamber Baikoff Phakic IOLs on the Cornea II-52
Posterior Chamber IOL Fixed Sclerally for Children with
Monocular Aphakia II-52
Aging of the Ciliary Sulcus on the Placement of Posterior
Chamber IOLs II-52
Cystic Epithelial Downgrowth: A Complication of Intraocular
Surgery II-52
Occurrence of Endophthalmitis After Secondary IOL Implantations II-52
Effect of Implantation of Silicone IOLs through Different
Types of Incisions II-53
Width of the Anterior Capsule Opening After IOL Implantations II-53
Evaluation of the Cellular Reaction on the Surface of PMMA IOLs II-53
Incidence of Glaucoma in Children after Cataract Extraction &
IOL Implantation II-53
Effect of Incision Length During IOL Implantation On Corneal
Astigmatism II-53
Occurrence of Capsular Capture During Silicone IOL Implants II-54
Evaluation of the Anis Circular Lens II-54
Effect of Foldable Intraocular Lens Insertion On Incision Width II-54
Corneal Complications After Cataract & IOL Surgery II-54
Side Effects of Oval IOLs Implantation II-54
Effects of Phacoemulsification & Small-incision IOL
Implantation on Incision Width II-55
Capsular Fibrotic Changes II-55
Suitable Lens After Cataract Surgery: Multifocal or Monofocal ? II-55
Aspheric IOL Improves Visual Performance II-55

8. REGULATIONS GOVERNING THE PRODUCTION AND APPROVAL OF IOLS II-56
IOL Compressibility Test II-56
IOL Vault Testing II-56
Haptic Fatigue Testing II-56
Dardenne Testing II-56
Process of IOL Approval II-56

9. PRODUCT APPROVALS/INTRODUCTIONS II-57
STAAR Surgical Obtains Approval for nanoFLEX™ Toric Collamer®
IOL in Europe II-57
Lenstec Launches Softec HD Oval IOL in the US II-57
Bausch & Lomb Rolls Out TORIC Version of enVista IOL in Europe II-57
Bausch & Lomb Gains FDA Clearance for enVista IOL II-57
Carl Zeiss Launches AT LISA tri 839MP II-57
FDA Approves Hoya’s iSymm™ and iSert™ IOLs II-58
Abbott Launches TECNIS® Toric 1-Piece IOL in Canada II-58
STAAR Surgical Receives CE Mark for KS-SP Preloaded Single
Piece Hydrophobic Acrylic IOL II-58
STAAR Surgical Receives Approval for Visian® ICL™ V4 in Brazil II-58
EU Awards CE Mark to nanoFLEX™ Collamer® IOL (EU) II-58
Bausch & Lomb Launches enVista IOL in Europe II-59
AMO Obtains FDA Clearance for TECNIS Multifocal 1-Piece IOL II-59
Abbott Unveils New Tecnis Toric IOL for European Eye Care
Markets II-59
Aaren Receives US FDA Approval for EC-3 IOLs II-59
Alcon Launches AcrySof IQ ReSTORMultifocal Toric Outside US II-60
Lenstec Receives FDA Nod forSoftec HD™ IOL II-60
Bausch & Lomb Unveils Crystalens® AO II-60
Abbott Obtains FDA Approval for TECNIS Multifocal 1-Piece IOL II-60
STAAR Receives Approval for Marketing Visian ICL in Japan II-61
STAAR Unveils NTIOL Approved nanoFLEX IOL II-61
Bausch & Lomb Rolls Out Akreos® MICS™ Lens II-61
STAAR Surgical Unveils Afinity™ Collamer Aspheric Single
Piece NTIOL II-61
Alcon Receives US FDA Approval for Aspheric AcrySof IQ Toric IOL II-61
Bausch & Lomb Secures FDA Approval for Marketing Crystalens
HD in Quarter Diopter Steps II-62
AcrySof IQ ReSTOR +3.0 Attains US FDA Approval II-62
AMO Secures US FDA Approval for TECNIS® Multifocal IOL II-62
STAAR’s KS-Ni Preloaded Silicone IOL Injector System Receives
Approval in Japan II-62
Hoya Surgical Optics Gets US FDA Approval for iSpheric™ Model
YA-60BB IOL II-62

10. RECENT INDUSTRY ACTIVITY II-63
Lumetrics Acquires Assets of WaveFront Sciences II-63
Alcon to Use ContourGT-x8 from Bruker II-63
Elenza Inks Series B Financing Agreement with Investors II-63
Alcon and CIBAVISION Merge into Novartis II-64
Carl Zeiss Acquires IOL and OVD Businesses of Imex II-64
STAAR and Ellex Ink Distribution Agreement II-65
Advanced Vision Science and Bausch & Lomb Ink License Agreement II-65
Abbott Snaps Up Visiogen II-65
Abbott Pockets Eye Care Major Advanced Medical Optics II-66
AMO and Alcon Sign Patent Cross-Licensing Agreement II-66
Bausch & Lomb Pockets eyeonics II-66
STAAR Acquires Canon Staar II-66
AMO Inks Agreement with Bausch & Lomb II-67
Coherent Changes Name to Clarion II-67

11. FOCUS ON SELECT PLAYERS II-68
Aaren Scientific, Inc. (US) II-68
Abbott Medical Optics, Inc. (US) II-68
Alcon, Inc. (US) II-69
Bausch & Lomb, Inc. (US) II-70
Carl Zeiss Meditec AG (Germany) II-71
Hoya Corporation (Japan) II-72
OPHTEC BV (Netherlands) II-72
Rayner Intraocular Lenses Limited (The United Kingdom) II-73
STAAR Surgical Company (US) II-73
The HumanOptics AG (Germany) II-74

12. GLOBAL MARKET PERSPECTIVE II-75
Table 7: World Recent Past, Current & Future Analysis for
Intraocular Lenses by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Latin America and Rest
of World Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) II-75

Table 8: World Historic Review for Intraocular Lenses by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2005 through 2009 (includes corresponding
Graph/Chart) II-76

Table 9: World 14-Year Perspective for Intraocular Lenses by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America and Rest of World Markets for Years 2005, 2012 &
2018 (includes corresponding Graph/Chart) II-77

Table 10: World Recent Past, Current & Future Market Analysis
for Standard Intraocular Lenses by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) II-78

Table 11: World Historic Review for Standard Intraocular
Lenses by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Latin America and Rest of
World Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2005 through 2009 (includes
corresponding Graph/Chart) II-79

Table 12: World 14-Year Perspective for Standard Intraocular
Lenses by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Markets for Years
2005, 2012 & 2018 (includes corresponding Graph/Chart) II-80

Table 13: World Recent Past, Current & Future Market Analysis
for Premium Intraocular Lenses by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America and Rest of World Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2010 through
2018 (includes corresponding Graph/Chart) II-81

Table 14: World Historic Review for Premium Intraocular Lenses
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America & Rest of World Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2005 through 2009 (includes corresponding
Graph/Chart) II-82

Table 15: World 14-Year Perspective for Premium Intraocular
Lenses by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Markets for Years
2005, 2012 & 2018 (includes corresponding Graph/Chart) II-83


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Current and Future Analysis III-1
Volume Analysis III-1
Value Analysis III-1
Imperative Need for Cataract Surgery III-1
A Snapshot of US Demographic Profile and Cataracts III-1
Table 16: Cataract Prevalence in the US by Age Group
(includes corresponding Graph/Chart) III-2
The State of the US Premium IOL Market III-2
Product Benefits Drive Sales of Premium IOLs III-3
Premium IOLs See Lethargic Growth in Adoption Rates III-3
Economy and Other Hurdles Rife en route Rapid Adoption of
Premium Lenses III-3
Lack of Surgeons’ Confidence Slows Down PC-IOL Sales III-4
Future Bodes Better Prospects for Presbyopia- Correcting IOLs III-4
Has the Delayed Approval for Crystalens been a Boon for US
Patients? III-5
Demand for Phakic IOLs - Yet to Pick Up III-5
Has the Initial Passion for Phakic IOLs Waned? III-6
Assessing the New Phakic IOLs on the Anvil III-6
Cataract and IOL Reimbursement in the US III-7
Table 17: Reimbursement in Cataract Procedures in the US
(2012): Percentage Breakdown of Payment for Procedures for
Medicare, Medicare Plus and Non-Medicare Insurers
(includes corresponding Graph/Chart) III-7
CMMS’ New Physician Fee Schedule - Is it a Jolt to
Ophthalmologists? III-7
Competitive Overview III-8
Table 18: Leading Players in the US IOL Market (2012):
Percentage Share Breakdown of Revenues for Alcon, AMO,
Bausch and Lomb and Others (includes corresponding
Graph/Chart) III-8

Table 19: Leading Players in the US Standard Monofocal Lens
Market (2012): Percentage Breakdown of Value Sales for
Alcon, Bausch & Lomb and Others (includes corresponding
Graph/Chart) III-8

Table 20: Leading Players in the US Premium Monofocal Lens
Market (2012): Percentage Breakdown of Value Sales for
Alcon, Abbott and Bausch & Lomb (includes corresponding
Graph/Chart) III-9

Table 21: Leading Brands in the US Refractive IOL Market
(2012): Percentage Breakdown of Value Sales for ReSTOR,
Crystalens, ReZoom, Tecnis Multifocal and Others (includes
corresponding Graph/Chart) III-9
Product Approvals/Launches III-9
Strategic Corporate Developments III-13
Select Players III-16
B.Market Analytics III-21
Table 22: US Recent Past, Current & Future Analysis for
Intraocular Lenses by Product Segment - Standard Intraocular
Lenses and Premium Intraocular Lenses (Toric and Others)
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-21

Table 23: US Recent Past, Current & Future Market Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses (Toric and
Others) Markets Independently Analyzed with Annual Sales
Figures in ‘000 Units
for Years 2010 through 2018
(includes corresponding Graph/Chart) III-22

Table 24: US Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses (Toric and Others) Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2005 through 2009 (includes corresponding Graph/Chart) III-23

Table 25: US Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses (Toric and Others) Markets Independently
Analyzed with Annual Sales Figures in ‘000 Units for Years
2005 through 2009 (includes corresponding Graph/Chart) III-24

Table 26: US 14-Year Perspective for Intraocular Lenses by
Product Segment - Percentage Breakdown of Dollar Sales for
Standard Intraocular Lenses and Premium Intraocular Lenses
(Toric and Others) Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-25

Table 27: US 14-Year Perspective for Intraocular Lenses by
Product Segment - Percentage Breakdown of Volume Sales for
Standard Intraocular Lenses and Premium Intraocular Lenses
(Toric and Others) Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-26

2. CANADA III-27
A.Market Analysis III-27
Current and Future Analysis III-27
Canadian IOL Market Outlook III-27
Canada follows the US in Cataract Surgery Reimbursements III-27
Product Launch III-27
B.Market Analytics III-28
Table 28: Canadian Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-28

Table 29: Canadian Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-29

Table 30: Canadian 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-30

3. JAPAN III-31
A.Market Analysis III-31
Current and Future Analysis III-31
Volume Analysis III-31
Value Analysis III-31
Hoya - Aiming High in Japanese and Global Markets III-31
Table 31: Leading Players in the Japanese IOL Market
(2012): Percentage Breakdown of Value Sales for Alcon
Japan, Hoya, AMO Japan and Others (includes corresponding
Graph/Chart) III-32
Product Approvals III-32
Hoya Corporation - A Leading Japanese IOL Producer III-32
B.Market Analytics III-34
Table 32: Japanese Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-34

Table 33: Japanese Recent Past, Current & Future Market
Analysis for Intraocular Lenses by Product Segment -
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets Independently Analyzed with Annual Sales Figures in
‘000 Units for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-35

Table 34: Japanese Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-36

Table 35: Japanese Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in ‘000 Units for Years 2005 through
2009 (includes corresponding Graph/Chart) III-37

Table 36: Japanese 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-38

Table 37: Japanese 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Volume
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-39

4. EUROPE III-40
A.Market Analysis III-40
Current and Future Analysis III-40
Volume Analysis III-40
Value Analysis III-40
Economic Crisis in EU and its Impact on Ophthalmology III-40
A Focus on the European Premium IOL Market III-42
Reimbursement - A Major Obstacle to Higher Penetration III-42
Major PC-IOLs in Europe III-42
AcrySofReSTOR Leads European Multifocal IOL Market III-43
List of Multifocal IOLs Approved/In-Use in Europe III-43
New Products Throng the European Diffractive Multifocal
IOL Market III-44
Refractive Multifocal IOLs in Europe III-44
Market Sees Increase in Options of Toric IOLs III-44
Phakic IOL - A Popular Lens Type in Europe III-44
Product Approvals/Launches III-45
B.Market Analytics III-47
Value Analysis III-47
Table 38: European Recent Past, Current & Future Analysis
for Intraocular Lenses by Geographic Region - France,
Germany, Italy, UK, Spain, Russia and Rest of Europe
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-47

Table 39: European Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-48

Table 40: European Historic Review for Intraocular Lenses
by Geographic Region - France, Germany, Italy, UK, Spain,
Russia and Rest of Europe Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2005
through 2009 (includes corresponding Graph/Chart) III-49

Table 41: European Historic Review for Intraocular Lenses
by Product Segment - Standard Intraocular Lenses and
Premium Intraocular Lenses Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2005
through 2009 (includes corresponding Graph/Chart) III-50

Table 42: European 14-Year Perspective for Intraocular
Lenses by Geographic Region - Percentage Breakdown of
Dollar Sales for France, Germany, Italy, UK, Spain, Russia
and Rest of Europe Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-51

Table 43: European 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-52
Volume Analysis III-53
Table 44: European Recent Past, Current & Future Market
Analysis for Intraocular Lenses by Product Segment -
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets Independently Analyzed with Annual Sales Figures
in ‘000 Units for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-53

Table 45: European Historic Review for Intraocular Lenses
by Product Segment - Standard Intraocular Lenses and
Premium Intraocular Lenses Markets Independently Analyzed
with Annual Sales Figures in ‘000 Units for Years 2005
through 2009 (includes corresponding Graph/Chart) III-54

Table 46: European 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Volume
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-55

4a. FRANCE III-56
A.Market Analysis III-56
Current and Future Analysis III-56
Premium Lenses Still Hold a Small Share in France III-56
B.Market Analytics III-57
Table 47: French Recent Past, Current & Future Analysis for
Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-57

Table 48: French Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-58

Table 49: French 14-Year Perspective for Intraocular Lenses
by Product Segment - Percentage Breakdown of Dollar Sales
for Standard Intraocular Lenses and Premium Intraocular
Lenses Markets for Years 2005, 2012 & 2018 (includes
corresponding Graph/Chart) III-59

4b. GERMANY III-60
A.Market Analysis III-60
Current and Future Analysis III-60
Select Players III-60
B.Market Analytics III-62
Table 50: German Recent Past, Current & Future Analysis for
Intraocular Lenses by Product Segment - Standard Intraocular
Lenses and Premium Intraocular Lenses Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2010 through 2018 (includes corresponding Graph/Chart) III-62

Table 51: German Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-63

Table 52: German 14-Year Perspective for Intraocular Lenses
by Product Segment - Percentage Breakdown of Dollar Sales
for Standard Intraocular Lenses and Premium Intraocular
Lenses Markets for Years 2005, 2012 & 2018 (includes
corresponding Graph/Chart) III-64

4c. ITALY III-65
A.Market Analysis III-65
Current and Future Analysis III-65
Reimbursement Issues Haunt Premium IOL Market III-65
B.Market Analytics III-66
Table 53: Italian Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-66

Table 54: Italian Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-67

Table 55: Italian 14-Year Perspective for Intraocular Lenses
by Product Segment - Percentage Breakdown of Dollar Sales
for Standard Intraocular Lenses and Premium Intraocular
Lenses Markets for Years 2005, 2012 & 2018 (includes
corresponding Graph/Chart) III-68

4d. THE UNITED KINGDOM III-69
A.Market Analysis III-69
Current and Future Analysis III-69
A Brief Overview of Cataract Reimbursement System in the UK III-69
Blanket Restriction Continue despite Government’s Ruling
against such Rationing III-69
Rationing Forces Patients to Resort to Self Pay III-70
Rayner Intraocular Lenses Limited - A Leading UK-Based IOL
Manufacturer III-70
B.Market Analytics III-71
Table 56: UK Recent Past, Current & Future Analysis for
Intraocular Lenses by Product Segment - Standard Intraocular
Lenses and Premium Intraocular Lenses Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2010 through 2018 (includes corresponding Graph/Chart) III-71

Table 57: UK Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-72

Table 58: UK 14-Year Perspective for Intraocular Lenses by
Product Segment - Percentage Breakdown of Dollar Sales for
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets for Years 2005, 2012 & 2018 (includes corresponding
Graph/Chart) III-73

4e. SPAIN III-74
A.Market Analysis III-74
Current and Future Analysis III-74
Strategic Corporate Development III-74
B.Market Analytics III-75
Table 59: Spanish Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-75

Table 60: Spanish Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-76

Table 61: Spanish 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-77

4f. RUSSIA III-78
A.Market Analysis III-78
Current and Future Analysis III-78
B.Market Analytics III-78
Table 62: Russian Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-78

Table 63: Russian Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-79

Table 64: Russian 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-80

4g. REST OF EUROPE III-81
A.Market Analysis III-81
Current and Future Analysis III-81
Torics Gain Popularity in Ireland III-81
Select Player III-81
B.Market Analytics III-82
Table 65: Rest of Europe Recent Past, Current & Future
Analysis for Intraocular Lenses by Product Segment -
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-82

Table 66: Rest of Europe Historic Review for Intraocular
Lenses by Product Segment - Standard Intraocular Lenses and
Premium Intraocular Lenses Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2005
through 2009 (includes corresponding Graph/Chart) III-83

Table 67: Rest of Europe 14-Year Perspective for
Intraocular Lenses by Product Segment - Percentage Breakdown
of Dollar Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-84

5. ASIA-PACIFIC III-85
A.Market Analysis III-85
Current and Future Analysis III-85
An Overview of the Asia-Pacific Cataract Market III-85
Lethargic Adoption Typifies Premium IOLs Market in Asia-
Pacific III-85
Demand in Asia-Pacific Basks around High-Growth Indian and
Chinese Markets III-86
B.Market Analytics III-86
Table 68: Asia-Pacific Recent Past, Current & Future
Analysis for Intraocular Lenses by Geographic Region -
China, India and Rest of Asia-Pacific Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2010 through 2018 (includes corresponding Graph/Chart) III-86

Table 69: Asia-Pacific Recent Past, Current & Future
Analysis for Intraocular Lenses by Product Segment -
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-87

Table 70: Asia-Pacific Historic Review for Intraocular
Lenses by Geographic Region - China, India and Rest of
Asia-Pacific Markets Independently Analyzed with Annual
Sales Figures in US$ Million for Years 2005 through 2009
(includes corresponding Graph/Chart) III-88

Table 71: Asia-Pacific Historic Review for Intraocular
Lenses by Product Segment - Standard Intraocular Lenses and
Premium Intraocular Lenses Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2005
through 2009 (includes corresponding Graph/Chart) III-89

Table 72: Asia-Pacific 14-Year Perspective for Intraocular
Lenses by Geographic Region - Percentage Breakdown of
Dollar Sales for China, India and Rest of Asia-Pacific for
Years 2005, 2012 & 2018 (includes corresponding Graph/Chart) III-90

Table 73: Asia-Pacific 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-91

5a. CHINA III-92
A.Market Analysis III-92
Current and Future Analysis III-92
Chinese IOL Market - An Overview III-92
B.Market Analytics III-93
Table 74: Chinese Recent Past, Current & Future Analysis
for Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes corresponding
Graph/Chart) III-93

Table 75: Chinese Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-94

Table 76: Chinese 14-Year Perspective for Intraocular
Lenses by Product Segment - Percentage Breakdown of Dollar
Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-95

5b. INDIA III-96
A.Market Analysis III-96
Current and Future Analysis III-96
An Overview of the EyeCare Market in India III-96
Hindrances to Market Growth III-96
IOL Market Scenario III-97
B.Market Analytics III-98
Table 77: Indian Recent Past, Current & Future Analysis for
Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-98

Table 78: Indian Historic Review for Intraocular Lenses by
Product Segment - Standard Intraocular Lenses and Premium
Intraocular Lenses Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2005 through
2009 (includes corresponding Graph/Chart) III-99

Table 79: Indian 14-Year Perspective for Intraocular Lenses
by Product Segment - Percentage Breakdown of Dollar Sales
for Standard Intraocular Lenses and Premium Intraocular
Lenses Markets for Years 2005, 2012 & 2018 (includes
corresponding Graph/Chart) III-100

5c. REST OF ASIA-PACIFIC III-101
A.Market Analysis III-101
Current and Future Analysis III-101
Strategic Corporate Development III-101
B.Market Analytics III-102
Table 80: Rest of Asia-Pacific Recent Past, Current &
Future Analysis for Intraocular Lenses by Product Segment -
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-102

Table 81: Rest of Asia-Pacific Historic Review for
Intraocular Lenses by Product Segment - Standard
Intraocular Lenses and Premium Intraocular Lenses Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2005 through 2009 (includes corresponding
Graph/Chart) III-103

Table 82: Rest of Asia-Pacific 14-Year Perspective for
Intraocular Lenses by Product Segment - Percentage Breakdown
of Dollar Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-104

6. LATIN AMERICA III-105
A.Market Analysis III-105
Current and Future Analysis III-105
Product Launch III-105
B.Market Analytics III-106
Table 83: Latin American Recent Past, Current & Future
Analysis for Intraocular Lenses by Product Segment -
Standard Intraocular Lenses and Premium Intraocular Lenses
Markets Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2010 through 2018 (includes
corresponding Graph/Chart) III-106

Table 84: Latin American Historic Review for Intraocular
Lenses by Product Segment - Standard Intraocular Lenses and
Premium Intraocular Lenses Markets Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2005
through 2009 (includes corresponding Graph/Chart) III-107

Table 85: Latin American 14-Year Perspective for
Intraocular Lenses by Product Segment - Percentage Breakdown
of Dollar Sales for Standard Intraocular Lenses and Premium
Intraocular Lenses Markets for Years 2005, 2012 & 2018
(includes corresponding Graph/Chart) III-108

7. REST OF WORLD III-109
A.Market Analysis III-109
Current and Future Analysis