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Global Surgical Incision Closures Industry

  • March 2015
  • -
  • Global Industry Analysts
  • -
  • 288 pages

This report analyzes the worldwide markets for Surgical Incision Closures in US$ Million by the following Product Segments: Stapler Products (Internal Stapler, Skin Staplers, Surgical/Ligature Clips, & Vascular Clips), Suture Products (Absorbable Sutures, & Non Absorbable), Hemostats, Tape Closures, and Tissue Sealants. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 51 companies including many key and niche players such as -

3M Healthcare
Abbott Laboratories
Advanced Medical Solutions Group Plc
Aesculap AG & Co. KG
Baxter International, Inc.

Table Of Contents

Global Surgical Incision Closures Industry


I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation and Reporting Level I-2 Quantitative Techniques and Analytics I-2 Product Definitions and Scope of Study I-3 Stapler Products.............. I-3 Internal Staplers.............. I-3 Skin Staplers.............. I-3 Surgical/Ligature Clips..............I-4 Vascular Clips.............. I-4 Sutures.............. I-4 Absorbable Sutures..............I-4 Non-Absorbable Sutures..............I-4 Hemostats.............. I-4 Tape Closures.............. I-4 Tissue Sealants/Adhesives..............I-4

II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW.............. II-1 Surgical Incision Closures - A Prelude II-1 Current and Future Analysis..............II-1 Developing Markets Hold Lucrative Potential for Wound Closure Devices.............. II-2 Maximizing on the ‘Minimal' Market II-2 Next Generation Closure Technologies Offer Lucrative Opportunities.............. II-2 Suture Products: Largest Market..............II-3 Staplers Compete with Sutures..............II-4 Tapes/Strips: Simplifying Closures II-4 Tissue Sealants: Gain in Popularity II-4 Why Use Adhesives and Sealants Over Sutures and Staples? II-5 Surgical Adhesive and Sealants Utility in Surgeries II-6 Gauging the Economic Benefits of Hemostats and Sealants II-6 Tissue Adhesives: On the Growth Curve II-7 Biomaterials and Synthetic Materials Mark Metamorphosis II-7 Advanced Wound Closure Devices: Comparing the US and European Markets.............. II-8 Market Gains from Increase in Cosmetic Surgeries II-8 Growing Focus on Reducing Hospital Stays Lends Traction II-9

2. COMPETITIVE SCENARIO.............. II-10 Table 1: Leading Players in the Global Sutures, Staples and Mechanical Closure Devices Market (2013): Percentage Breakdown of Sales for Ethicon, Medtronic, B. Braun and Others (includes corresponding Graph/Chart)..............II-10

Table 2: Leading Players in the Global Surgical Tapes Market (2013): Percentage Breakdown of Sales for 3M Healthcare, Ethicon, B.Braun and Others (includes corresponding Graph/Chart).............. II-10

Table 3: Leading Players in the Global Fibrin and Other Sealants Market (2013): Percentage Breakdown of Sales for Ethicon, Baxter International, and Others (includes corresponding Graph/Chart)..............II-11

Table 4: Leading Players in the Global Hemostats Market (2013): Percentage Breakdown of Sales for Ethicon, CSL Behring, Pfizer, Equimedical BV and Others (includes corresponding Graph/Chart)..............II-11

Table 5: Leading Players in the Global High Strength Medical Adhesives Market (2013): Percentage Breakdown of Sales for Ethicon, Cryolife, B.Braun and Others (includes corresponding Graph/Chart).............. II-11 Product Mix of Leading Players in the Traditional Surgical Incision Closures Market..............II-12

3. MARKET TRENDS and DRIVERS..............II-13 Technological Advancements Drive Growth II-13 Surgical Adhesives and Glues - The Future of Wound Closure Devices.............. II-13 Companies Focus on Non-Invasive Closure Products II-14 Developments in Laparoscopy Call for New Product Advancements II-15 Absorbable Sutures to Race Ahead over Non-Absorbable Sutures II-15 Barbed Sutures - The New Generation Sutures II-16 Innovative Products Stabilize Growth in the Staplers Market II-17 TopClosure System - An Alternative Approach for Mass-Casualty Situations.............. II-18 Nanotechnology in Incision Closures II-19 Hemostatic Agents: In Close Competition with Sutures Technology II-19 Hemostats Pose Threat to Tissue Sealants II-20 Topical Skin Adhesives Gain Acceptance in Radiological Applications.............. II-20 Adhesives and Sealants to Witness Rapid Gains in Cardiovascular Procedures..............II-20 Fibrin Sealants Focus on Minimizing Risk of Infection II-21

4. PRODUCT ANALYSIS.............. II-22 Surgical Stapler Products..............II-22 Stapler Products: Replacement for Manual Suturing II-22 Internal Staplers.............. II-23 Skin Staplers.............. II-23 Surgical/Ligature Clips..............II-23 Vascular Clips.............. II-23 Sutures Products.............. II-23 Sweeping Changes in the Kinds of Suture Material Used II-23 Applications of Sutures..............II-24 Sutures Classification..............II-24 Absorbable and Non-Absorbable Surgical Suture II-24 Monofilament and Multifilament II-24 Absorbable Suture Materials..............II-24 Surgical Gut or Catgut..............II-24 Chromic Gut.............. II-24 Fast-Absorbing Gut..............II-25 Polyglycolic Acid.............. II-25 Polyglactin.............. II-25 Polydioxanone.............. II-25 Polytrimethylene Carbonate..............II-25 Polyglecaprone.............. II-26 Uses of Absorbable Sutures..............II-26 Characteristics of Absorbable Sutures II-26 Non-Absorbable Suture Materials II-26 Silk.............. II-27 Nylon.............. II-27 Polyester.............. II-27 Polypropylene.............. II-27 Polybutester.............. II-27 Uses of Non-Absorbable Sutures II-27 Characteristics of Non-Absorbable Sutures II-28 Synthetic Absorbable Sutures Dominate Suture Markets II-28 Tissue Sealants.............. II-28 Fibrin Sealants.............. II-28 Tapes.............. II-29 Comparison of Advantages and Disadvantages of Different Surgical Closure Devices/ Procedures II-29 Hemostats.............. II-30 List of Select Hemostat Products Available II-30

5. PRODUCT LAUNCHES/DEVELOPMENTS..............II-31 Cardica Introduces Novel MicroCutter XCHANGE30 Short Shaft Handle II-31 Cardica Launches Curved Tip Cartridge for MicroCutter XCHANGE® 30 II-31 Cayenne Medical Unveils SureLock™ All-Suture Anchor System II-31 UCL Hospitals Develops Novel Surgical Clip II-31 ZipLine® Medical Launches Range of Zip Devices II-31 IonMed to Introduce BioWeld1..............II-31 ZipLine® Medical Launches a Non-invasive Skin Closure Device II-31 Theragenics Introduces PLUS Range of Antibacterial Sutures II-32 AD Surgical Unveils UNIFY® Polyester and Cable Nylon Non- absorbable Sutures.............. II-32 Micro International to Introduce Permaseal II-32 Covidien Unveils AS Meniscal™ Repair Device II-32 Teleflex Introduces Weck Efx™ Endo Fascial Closure System and Range of Weck® Access Devices II-32 Ethicon Unveils Range of STRATAFIX™ Knotless Tissue Control Devices.............. II-32 ZSX Medical to Introduce Zip-Stitch Clips II-32 Covidien Introduces V-Loc™ Knotless Suturing Reloads II-33 Covidien Introduces Endo GIA™ Radial Reload II-33 Omnia Launches PTFE Sutures..............II-33 Medline Industries Launches Octylseal™ Tissue Adhesive II-33 AccessClosure Unveils MynxGrip Vascular Closure Device II-33

6. RECENT INDUSTRY ACTIVITY..............II-34 Medtronic Takes Over Covidien..............II-34 Cohera Medical Inks Agreement with B.Braun Surgical over Distribution of TissuGlu® Surgical Adhesives in Parts of Europe.............. II-34 China Materialia Invests US$5.7 million in ZipLine® Medical II-34 The Medicines Company Takes Over Tenaxis Medical II-34 Gecko Biomedical Bags €8 Million in Series A Financing to Develop Biodegradable Surgical Wound Closure Solutions II-34 Teleflex Acquires Microlaparoscopy Technology of InnoLap Surgical II-34 TPG Growth Acquires Sutures India II-35 Tenaxis Medical Obtains BSI Approval for ArterX Surgical Sealant II-35 Abbott Acquires OptiMedica..............II-35 Theragenics Inks Definitive Merger Agreement with Juniper Investment.............. II-35 Advanced Medical Solutions Obtains FDA Approval for its New Product.............. II-35 Smith and Nephew to Acquire Healthpoint Biotherapeutics II-35 Covidien Obtains FDA 510(k) Clearance for iDrive™ Ultra Powered Stapling System..............II-35

7. FOCUS ON SELECT PLAYERS..............II-36 3M Healthcare (US)..............II-36 Abbott Laboratories (US)..............II-36 Advanced Medical Solutions Group Plc (UK) II-36 Aesculap AG and Co. KG (Germany) II-37 Baxter International, Inc. (US)..............II-37 CP Medical, Inc. (US)..............II-38 Derma Sciences, Inc. (US)..............II-38 Ethicon Endo-Surgery, Inc. (US)..............II-39 Medtronic, Inc. (US)..............II-39 Smith and Nephew plc (UK)..............II-40 Surgical Specialties Corporation (US), Inc. II-40 Teleflex Medical OEM (US)..............II-41

8. GLOBAL MARKET PERSPECTIVE..............II-42 Table 6: World Recent Past, Current and Future Analysis for Surgical Incision Closures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-42

Table 7: World Historic Review for Surgical Incision Closures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-43

Table 8: World 14-Year Perspective for Surgical Incision Closures by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-44 Surgical Incision Closures Market by Product Segment II-45 Table 9: World Recent Past, Current and Future Analysis for Stapler Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-45

Table 10: World Historic Review for Stapler Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-46

Table 11: World 14-Year Perspective for Stapler Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-47

Table 12: World Recent Past, Current and Future Analysis for Stapler Products by Product Segment - Internal Stapler, Skin Staplers, Surgical/Ligature Clips, and Vascular Clips Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. II-48

Table 13: World Historic Review for Stapler Products by Product Segment - Internal Stapler, Skin Staplers, Surgical/Ligature Clips, and Vascular Clips Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-49

Table 14: World 14-Year Perspective for Stapler Products by Product Segment - Percentage Breakdown of Dollar Sales for Internal Stapler, Skin Staplers, Surgical/ Ligature Clips, and Vascular Clips Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............II-50

Table 15: World Recent Past, Current and Future Analysis for Internal Stapler Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-51

Table 16: World Historic Review for Internal Stapler Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-52

Table 17: World 14-Year Perspective for Internal Stapler Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-53

Table 18: World Recent Past, Current and Future Analysis for Skin Stapler Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-54

Table 19: World Historic Review for Skin Stapler Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-55

Table 20: World 14-Year Perspective for Skin Stapler Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-56

Table 21: World Recent Past, Current and Future Analysis for Surgical/Ligature Clips Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-57

Table 22: World Historic Review for Surgical/Ligature Clips Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-58

Table 23: World 14-Year Perspective for Surgical/ Ligature Clips Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-59

Table 24: World Recent Past, Current and Future Analysis for Vascular Clips Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-60

Table 25: World Historic Review for Vascular Clips Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-61

Table 26: World 14-Year Perspective for Vascular Clips Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-62

Table 27: World Recent Past, Current and Future Analysis for Suture Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-63

Table 28: World Historic Review for Suture Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-64

Table 29: World 14-Year Perspective for Suture Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-65

Table 30: World Recent Past, Current and Future Analysis for Suture Products by Product Segments - Absorbable Sutures and Non-Absorbable Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-66

Table 31: World Historic Review for Suture Products by Product Segments - Absorbable Sutures and Non-Absorbable Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-67

Table 32: World 14-Year Perspective for Stapler Products by Product Segments - Percentage Breakdown of Dollar Sales for Absorbable Sutures and Non-Absorbable Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-68

Table 33: World Recent Past, Current and Future Analysis for Absorbable Sutures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-69

Table 34: World Historic Review for Absorbable Sutures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-70

Table 35: World 14-Year Perspective for Absorbable Sutures by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-71

Table 36: World Recent Past, Current and Future Analysis for Non-Absorbable Sutures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-72

Table 37: World Historic Review for Non-Absorbable Sutures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-73

Table 38: World 14-Year Perspective for Non-Absorbable Sutures by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-74

Table 39: World Recent Past, Current and Future Analysis for Hemostat Closures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-75

Table 40: World Historic Review for Hemostat Closures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-76

Table 41: World 14-Year Perspective for Hemostat Closures by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-77

Table 42: World Recent Past, Current and Future Analysis for Tape Closures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-78

Table 43: World Historic Review for Tape Closures by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-79

Table 44: World 14-Year Perspective for Tape Closures by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-80

Table 45: World Recent Past, Current and Future Analysis for Tissue Sealants by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-81

Table 46: World Historic Review for Tissue Sealants by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-82

Table 47: World 14-Year Perspective for Tissue Sealants by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) II-83

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Outlook.............. III-1 Surgical Incision Market - Overview III-1 Advanced Wound Closure Devices on Strong Growth Path III-1 Rising Elderly Population Indicate More Room for Growth III-2 Table 48: Increase in Number of Surgeries in the US (2001-2010, 2010-2020) (in %) (includes corresponding Graph/Chart).............. III-3 Market for Surgical Sealants III-3 Fibrin Sealants..............III-4 Table 49: Leading Players in the US Fibrin Sealants Market (2014): Percentage Share Breakdown by Value Sales for Baxter International, Haemacure/Angiotech, and Others (includes corresponding Graph/Chart) III-4 Low Awareness, Rigid FDA Approvals Restrain Hemostats Tissue Sealants Growth..............III-4 Table 50: Associated Costs of Hemostat Agents used in the US Surgical Market (includes corresponding Graph/Chart) III-5 Sutures - Holding Their Own..............III-6 Synthetic Absorbables Gain Popularity III-6 Leading Players..............III-6 Table 51: Leading Players in the US Suture Products Market (2013): Percentage Share Breakdown by Value Sales for Ethicon Inc., Covidien, and Others (includes corresponding Graph/Chart).............. III-6 Surgical Stapling Market..............III-6 Obesity Numbers Drive the Surgical Stapling Market III-7 Table 52: Proportion (%) of Obesity in the US Overweight Population by Age Group (includes corresponding Graph/Chart).............. III-7 Leading Players..............III-8 Table 53: Leading Players in the US Stapler Products Market (2013): Percentage Share Breakdown by Value Sales for Ethicon Endo-Surgery, Covidien, 3M Healthcare and Others (includes corresponding Graph/Chart) III-8 Ligature Clips.............. III-8 Table 54: Leading Players in the US Ligature Clips Market (2013) Percentage Share Breakdown by Value Sales for Covidien, Ethicon, Teleflex Medical, Aesculap and Others (includes corresponding Graph/Chart) III-8 Adhesive Strips.............. III-9 Table 55: Leading Players in the US Strips Market (2013) - Percentage Share Breakdown by Value Sales for 3M Healthcare, Derma Sciences, and Others (includes corresponding Graph/Chart)..............III-9 Product Launches/Developments..............III-9 Recent Industry Activity..............III-11 Key Players.............. III-12 B.Market Analytics..............III-17 Table 56: US Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-17

Table 57: US Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-18

Table 58: US 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-19

2. CANADA.............. III-20 Market Analysis.............. III-20 Table 59: Canadian Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-21

Table 60: Canadian Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-22

Table 61: Canadian 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-23

3. JAPAN.............. III-24 A.Market Analysis.............. III-24 Wound and Tissue Management Market to Witness Growth III-24 B.Market Analytics..............III-25 Table 62: Japanese Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-25

Table 63: Japanese Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-26

Table 64: Japanese 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-27

4. EUROPE.............. III-28 A.Market Analysis.............. III-28 Wound Closure Devices Market in Europe III-28 Tissue Sealant Market in Europe III-28 Gaining from Increasing Surgical Volumes III-29 Increase in Demand for Synthetic Absorbable Sutures III-29 B.Market Analytics..............III-30 Table 65: European Recent Past, Current and Future Analysis for Surgical Incision Closures by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-30

Table 66: European Historic Review for Surgical Incision Closures by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-31

Table 67: European 14-Year Perspective for Surgical Incision Closures by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart) III-32

Table 68: European Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-33

Table 69: European Historic Review for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-34

Table 70: European 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-35

4a. FRANCE.............. III-36 A.Market Analysis.............. III-36 Recent Industry Activity..............III-36 B.Market Analytics..............III-37 Table 71: French Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-37

Table 72: French Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-38

Table 73: French 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/ Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-39

4b. GERMANY.............. III-40 A.Market Analysis.............. III-40 Largest European Market for Surgical Incision Closures III-40 Aesculap ag and co. Kg - key player III-40 B.Market Analytics..............III-41 Table 74: German Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-41

Table 75: German Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-42

Table 76: German 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/ Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-43

4c. ITALY.............. III-44 A.Market Analysis.............. III-44 Product Launch.............. III-44 B.Market Analytics..............III-45 Table 77: Italian Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-45

Table 78: Italian Historic Review for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-46

Table 79: Italian 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/ Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-47

4d. THE UNITED KINGDOM..............III-48 A.Market Analysis.............. III-48 Product Development..............III-48 Recent Industry Activity..............III-48 Key Players.............. III-48 B.Market Analytics..............III-50 Table 80: UK Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-50

Table 81: UK Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-51

Table 82: UK 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-52

4e. SPAIN.............. III-53 Market Analysis.............. III-53 Table 83: Spanish Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-54

Table 84: Spanish Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-55

Table 85: Spanish 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-56

4f. RUSSIA.............. III-57 Market Analysis.............. III-57 Table 86: Russian Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-58

Table 87: Russian Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-59

Table 88: Russian 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-60

4g. REST OF EUROPE.............. III-61 A.Market Analysis.............. III-61 Product Launches..............III-61 B.Market Analytics..............III-62 Table 89: Rest of Europe Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-62

Table 90: Rest of Europe Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-63

Table 91: Rest of Europe 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-64

5. ASIA-PACIFIC.............. III-65 A.Market Analysis.............. III-65 Advanced Wound Closure Devices Growing in Prominence III-65 B.Market Analytics..............III-66 Table 92: Asia-Pacific Recent Past, Current and Future Analysis for Surgical Incision Closures by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-66

Table 93: Asia-Pacific Historic Review for Surgical Incision Closures by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-67

Table 94: Asia-Pacific 14-Year Perspective for Surgical Incision Closures by Geographic Region - Percentage Breakdown of Dollar Sales for China, India and Rest of Asia-Pacific Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-68

Table 95: Asia-Pacific Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-69

Table 96: Asia-Pacific Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-70

Table 97: Asia-Pacific 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-71

5a. CHINA.............. III-72 A.Market Analysis.............. III-72 Current and Future Analysis..............III-72 Recent Industry Activity..............III-72 Player Review: Qingdao Kingston Medical Devices Co. III-72 B.Market Analytics..............III-73 Table 98: Chinese Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-73

Table 99: Chinese Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-74

Table 100: Chinese 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/ Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-75

5b. INDIA.............. III-76 A.Market Analysis.............. III-76 Medical Tourism Offers New Growth Opportunities III-76 Table 101: Estimated Cost of Select Medical Procedures in India.............. III-77 Recent Industry Activity..............III-77 Pal Surgical Works - An Important Regional Player III-77 B.Market Analytics..............III-78 Table 102: Indian Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-78

Table 103: Indian Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-79

Table 104: Indian 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart).............. III-80

5c. REST OF ASIA-PACIFIC..............III-81 Market Analysis.............. III-81 Table 105: Rest of Asia-Pacific Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-82

Table 106: Rest of Asia-Pacific Historic Review for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/ Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-83

Table 107: Rest of Asia-Pacific 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-84

6. LATIN AMERICA.............. III-85 Market Analysis.............. III-85 Table 108: Latin American Recent Past, Current and Future Analysis for Surgical Incision Closures by Geographic Region - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-86

Table 109: Latin American Historic Review for Surgical Incision Closures by Geographic Region - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-87

Table 110: Latin American 14-Year Perspective for Surgical Incision Closures by Geographic Region - Percentage Breakdown of Dollar Sales for Brazil and Rest of Latin America Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-88

Table 111: Latin American Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-89

Table 112: Latin American Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-90

Table 113: Latin American 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-91

6a. BRAZIL.............. III-92 Market Analysis.............. III-92 Table 114: Brazilian Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-93

Table 115: Brazilian Historic Review for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-94

Table 116: Brazilian 14-Year Perspective for Surgical Incision Closures by Product Group/ Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-95

6b. REST OF LATIN AMERICA..............III-96 Market Analysis.............. III-96 Table 117: Rest of Latin America Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-97

Table 118: Rest of Latin America Historic Review for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-98

Table 119: Rest of Latin America 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-99

7. REST OF WORLD.............. III-100 A.Market Analysis.............. III-100 Product Launch.............. III-100 B.Market Analytics..............III-101 Table 120: Rest of World Recent Past, Current and Future Analysis for Surgical Incision Closures by Product Group/Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-101

Table 121: Rest of World Historic Review for Surgical Incision Closures by Product Group/ Segment - Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-102

Table 122: Rest of World 14-Year Perspective for Surgical Incision Closures by Product Group/Segment - Percentage Breakdown of Dollar Sales for Stapler Products (Internal Staplers, Skin Staplers, Surgical/Ligature Clips and Vascular Clips), Suture Products (Absorbable Sutures and Non-Absorbable Sutures), Hemostats, Tape Closures and Tissue Sealants Markets for Years 2007, 2015 and 2020 (includes corresponding Graph/Chart)..............III-103

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 51 (including Divisions/Subsidiaries - 61)

The United States (39) Canada (3) Europe (16) - France (1) - Germany (6) - The United Kingdom (6) - Italy (1) - Spain (1) - Rest of Europe (1) Asia-Pacific (Excluding Japan) (2) Middle East (1)

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