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Global Cholesterol & Other Cardiovascular Testing Industry

  • March 2012
  • -
  • Global Industry Analysts
  • -
  • 294 pages

This report analyzes the worldwide markets for Cholesterol & Other Cardiovascular Testing in Million Units by the following Product Segments: Lipid Panel Test/Complete Lipid Profile, Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein Tests. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. Also, a six-year historic analysis is provided for these markets. The report profiles 42 companies including many key and niche players such as AccuTech, LLC, Alere, Inc, Axis-Shield Plc, Beckman Coulter, Inc., F. Hoffmann-La Roche Ltd., Home Access Health Corporation, Polymer Technology Systems, Inc., and Siemens Healthcare Diagnostics, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

Table Of Contents

Global Cholesterol and Other Cardiovascular Testing Industry




I. INTRODUCTION, METHODOLOGY and PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation and Reporting Level I-3
Quantitative Techniques and Analytics I-3
Product Definitions and Scope of Study I-3
Lipid Panel Test/Complete Lipid Profile I-3
Total Cholesterol Test I-4
HDL Cholesterol Test I-4
Apolipoprotein B I-4
Other Apolipoprotein Tests I-4


II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW II-1
Global Market Outlook II-1
Tests Conducted Worldwide II-1
Home/OTC Cholesterol Test Kits Market: A Review II-1
Growth Drivers II-2
Aging Population Drives Home Testing Market II-2
Extensive Awareness Campaigns for Common People II-2
Global In-Vitro Diagnostic Products Market: An Overview II-2
Growth Trends II-3
Table 1: Global In-Vitro Diagnostics Products Market (2007):
Percentage Breakdown of Value Sales for North America,
Europe, Japan and Rest of World (includes corresponding
Graph/Chart) II-4
Established Players Dominate the Fragmented Market II-4
Table 2: Leading Players in the Global In-Vitro Diagnostics
Market (2009): Percentage Breakdown of Value Sales for Roche
Diagnostics, Abbott Diagnostics, Ortho/ LifeScan,
Bayer/Siemens, Beckman Coulter, BD, Dade Behring, bioMerieux
and Others (includes corresponding Graph/Chart) II-4
Cardiac IVD Market to Grow II-5

2. AN INSIGHT INTO CARDIOVASCULAR DISEASES II-6
The Heart of Heart Problems II-6
Types of Cardiovascular Diseases/Disorders II-6
Coronary Artery Disease II-6
Hyperlipidemia - An Important Risk Factor of Heart Disease II-6
Hypertension - The Silent Killer II-7
Two-Pronged Approach to Counter CVD II-8
Cardiovascular Risk Assessment II-8
Reality Check II-8

3. GOOD and BAD OF CHOLESTEROL II-10
Blood Cholesterol - The Principal Cardiac Risk Marker II-10
Types of Cholesterol II-10
Total Cholesterol (TC) II-10
High Density Lipoprotein (HDL) II-11
Low Density Lipoprotein (LDL) / Very Low Density Lipoprotein
(VLDL) II-11
Triglycerides (TRG) II-11
Glucose (GLU) II-11
Alanine Aminotransferase (ALT) II-11
Outcomes of High Blood Cholesterol II-11
Atherosclerosis II-11
Coronary Heart Disease (CHD) II-11
Risk Factors and Risk Levels II-12
Risk Factors II-12
Risk Levels II-12
Risk Level Based on Total Cholesterol Concentration II-12
LDL-Cholesterol Risk Levels II-12
HDL-Cholesterol Risk Levels II-13
Triglyceride Risk Levels II-13

4. CHOLESTEROL TESTING and CVD RISK ASSESSMENT TECHNIQUES II-14
Cholesterol Testing II-14
Need for Cholesterol Testing II-14
Candidates for Cholesterol Testing II-14
Test Procedure II-15
Time of Testing - Crucial for Heart Disease Patients II-15
Types of Cholesterol Testing II-16
Lipid Panel Test/Lipid Profile II-16
Total Cholesterol Test II-17
HDL Cholesterol Test II-17
Apolipoprotein Tests II-17
Apolipoprotein A-1 Test II-17
Apolipoprotein B100 Test II-18
ApoE Genotyping Test II-18
Apolipoprotein CII II-18
Other Cholesterol Markers II-18
LDL Cholesterol Testing II-18
LDL Cholesterol Test - The First Cholesterol Testing Method II-18
Triglycerides/VLDL Cholesterol Testing II-19
RLP Cholesterol II-19
Non Instrumented Technologies II-19
Heart Disease Diagnosis Tests II-19
Non-Invasive Tests II-20
Invasive Tests II-20
Other CVD Markers II-20
Creatine Kinase MB II-21
Troponin T and Troponin I II-21
Myoglobin II-21
P-selectin Profile II-21
C-reactive Protein II-22
Endothelial Dysfunction II-22
Homocysteine II-22
Plasminogen Activator Inhibitor-1 II-23
s-100 Protein II-23
Thrombus Precursor Protein II-24
Other Cardiac Markers II-24

5. POINT OF CARE and HOME CHOLESTEROL TESTING II-25
Point of Care (POC) Medical Diagnostics II-25
Table 3: Global Point of Care Diagnostics Market (2008):
Percentage Breakdown of Value Sales by Segment - Hospital
Labs, Commercial Labs, Self Testing and Point of Care
(includes corresponding Graph/Chart) II-25
POC Testing Market II-25
Table 4: Global Cholesterol Point-of-Care Rapid Tests Market
(2009): Market Shares of Leading Players by Value Sales for
Inverness Medical, Roche, Abaxis, and Others (includes
corresponding Graph/Chart) II-26
Development of Home Cholesterol Testing Kits II-26
Cholesterol and Other Cardiovascular Test Kits Offered by
Leading Companies II-26

6. CHOLESTEROL CONTROL and TREATMENT MODALITIES II-27
Prevention is Better than Cure II-27
Dietary Therapy II-27
Healthy Diet II-27
Exercises II-28
Drug Therapy II-28
Classification of Cholesterol Lowering Drugs II-28
Bile Acid Sequestrants II-28
Nicotinic Acid II-29
HMG CoA Reductase Inhibitors (Statins) II-29
Other Drugs (Fibric Acids and Probucol) II-29
Testing After Commencing Drug Therapy II-29

7. PRODUCT INTRODUCTIONS/INNOVATIONS II-31
SpectraCell Laboratories Launches Lp-PLA2 Test II-31
Polymer Technology Launches Cardio Diagnostic Analyzer II-31
Digital Division Introduces Cholesterol Screening Locator II-31
Interleukin Genetics Unveils Improved Test Report Format for
Heart Health Genetic Test II-31
Axis-Shield to Develop Lipid Panel Test for Afinionâ„¢ Point-of
-Care System II-32
Home Access Health Launches CheckUp America Cholesterol Panel II-32
Cholestech Launches Lipid Profile ALT Test Cassette II-32
Home Access Health Develops an Algorithm for Home Test II-32
Cholestech Unveils Innovative Dermatology Kit II-33
Beckman Coulter Unveils UniCel® DxI 600 Access® Immunoassay
System II-33
Polymer Technology Systems Launches Direct LDL Cholesterol Test II-34
Dade Behring Unveils CardioPhase® hsCRP Test II-34
PTS Introduces First Ever Direct LDL Cholesterol Test II-35

8. RECENT INDUSTRY ACTIVITY II-36
Miraculins Acquires PreMD's PREVU(i) Skin Cholesterol Test Assets II-36
Kardia Health Systems Partners with TomTec Imaging Systems II-36
BioMerieux Takes Over Meikang Biotech II-36
Inverness Medical Innovations Adopts New Name II-36
Aurora Health Care Partners with Celera II-37
iZumi Bio Merges Business with Pierian to Create iPierian II-37
Medical Technologies Collaborates with NASA for Cardiovascular
Testing II-37
Berkeley HeartLabs Inks Agreements with Geisinger Medical
Center and Proven Diagnostics II-38
ARCA biopharma and Nuvelo Complete Merger II-38
Thermo Fisher Scientific Acquires B.R.A.H.M.S. II-38
Mediscience Technology Corporation Acquires SensiVida Medical
Systems II-38

9. STRATEGIC CORPORATE DEVELOMPENTS - A HISTORIC PERSPECTIVE BUILDER II-39
Medrad Merges Operations with Possis Medical II-39
Roche Inks Agreement with Response Biomedical II-39
Dynatek Dalta Scientific Instruments Inks Agreement with State
Food and Drug Administration II-39
Abbott's TRILIPIX Receives Approval from FDA II-39
Signalife Establishes Signalcare II-40
Amic Inks Licensing Deal with Roche Diagnostics II-40
GE Healthcare Collaborates with Boston Scientific II-40
TRICARE Includes Atherotech's VAP® Test II-40
PreMD Receives NSE Letter from US FDA for POC Skin Cholesterol
Test II-41
Amic Gains License for Roche's Cardiac Marker II-41
Acrongenomics and Molecular Vision Enter into Joint
Collaboration Agreement II-41
diaDexus and Fisher HealthCare Sign Agreement II-42
Beckman Coulter Partners for Cardiovascular Research Project II-42
Siemens Acquires Bayer's Diagnostic Division II-42
Response Biomedical Gains Approval to Sell RAMII® NT- proBNP Test II-43
Endothelix Obtains FDA Approval for VENDYS® Cardiovascular Test II-43
Cholestech Receives CLIA Waived Status for Lipid Profile ALT
Test Panel II-43
Kellogg Partners with Omron Healthcare and BIOSAFE® II-44
Siemens Acquires Dade Behring II-44
Inverness Medical Innovations Concludes Cholestech Acquisition II-44
QuantRX Biomedical Increases Stake in FluoroPharma II-45
Celera Takes Over Berkeley HeartLab II-45
Inverness Medical Innovations Completes Acquisition of HemoSense II-45
LipoScience and BioReference Announce Collaboration II-46
PreMD and AstraZeneca Sign Distribution Agreement II-46
Atherotech Reaches an Agreement with Source Scientific II-46
Siemens Acquires Diagnostic Products Corporation II-47
Nanogen Acquires Spectral's Cardiac Test Division II-47
Instant Technologies Takes Over Accu-Stat Diagnostics II-47
Source Scientific and Atherotech Collaborate for VAP Test Devices II-48
Abbott Receives Non-exclusive Sublicense for Diagnostic Use of
PIGF II-48
Cholestech to Supply LDX® System to Mexican Ministry of
Communications and Tranportation II-48

10. FOCUS ON SELECT PLAYERS II-49
AccuTech, LLC (US) II-49
Alere, Inc.(US) II-49
Axis-Shield Plc (UK) II-50
Beckman Coulter, Inc. (US) II-50
F. Hoffmann-La Roche Ltd (Switzerland) II-51
Home Access Health Corporation (US) II-51
Polymer Technology Systems, Inc. (US) II-52
Siemens Healthcare Diagnostics, Inc. (US) II-52

11. GLOBAL MARKET PERSPECTIVE II-54
Table 5: World Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Geographic
Region - US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America and Rest of World Independently Analyzed
with Annual Sales Figures in Million Units for Years 2009
through 2017 (includes corresponding Graph/Chart) II-54

Table 6: World Historic Review for Cholesterol and Other
Cardiovascular Testing by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America,
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) II-55

Table 7: World 15-Year Perspective for Cholesterol and Other
Cardiovascular Testing by Geographic Region - Percentage
Breakdown of Unit Sales for US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan), Latin America and Rest of
World Markets for Years 2003, 2011 and 2017 (includes
corresponding Graph/Chart) II-56

Table 8: World Recent Past, Current and Future Analysis for
Lipid Panel Test/Complete Lipid Profile Testing by Geographic
Region -US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Independently
Analyzed with Annual Sales Figures in Million Units for Years
2009 through 2017 (includes corresponding Graph/Chart) II-57

Table 9: World Historic Review for Lipid Panel Test/ Complete
Lipid Profile Testing by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America
and Rest of World Markets Independently Analyzed with Annual
Sales Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) II-58

Table 10: World 15-Year Perspective for Lipid Panel Test/
Complete Lipid Profile Testing by Geographic Region -
Percentage Breakdown of Unit Sales for US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Latin America, and
Rest of World Markets for Years 2003, 2011 and 2017 (includes
corresponding Graph/Chart) II-59

Table 11: World Recent Past, Current and Future Analysis for
Total Cholesterol Testing by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America,
and Rest of World Independently Analyzed with Annual Sales
Figures in Million Units for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-60

Table 12: World Historic Review for Total Cholesterol Testing
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2003 through 2008 (includes corresponding
Graph/Chart) II-61

Table 13: World 15-Year Perspective for Total Cholesterol
Testing by Geographic Region - Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2003, 2011 and 2017 (includes corresponding Graph/Chart) II-62

Table 14: World Recent Past, Current and Future Analysis for HDL
Cholesterol Testing by Geographic Region - US, Canada, Japan,
Europe, Asia-Pacific (excluding Japan), Latin America, and
Rest of World Independently Analyzed with Annual Sales Figures
in Million Units for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-63

Table 15: World Historic Review for HDL Cholesterol Testing by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2003 through 2008 (includes corresponding
Graph/Chart) II-64

Table 16: World 15-Year Perspective for HDL Cholesterol
Testing by Geographic Region - Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2003, 2011 and 2017 (includes corresponding Graph/Chart) II-65

Table 17: World Recent Past, Current and Future Analysis for
Apolipoprotein B Tests by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America,
and Rest of World Independently Analyzed with Annual Sales
Figures in Million Units for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-66

Table 18: World Historic Review for Apolipoprotein B Tests by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2003 through 2008 (includes corresponding
Graph/Chart) II-67

Table 19: World 15-Year Perspective for Apolipoprotein B Tests
by Geographic Region - Percentage Breakdown of Unit Sales for
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan),
Latin America, and Rest of World Markets for Years 2003, 2011
and 2017 (includes corresponding Graph/Chart) II-68

Table 20: World Recent Past, Current and Future Analysis for
Other Apolipoprotein Tests by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan), Latin America,
and Rest of World Independently Analyzed with Annual Sales
Figures in Million Units for Years 2009 through 2017
(includes corresponding Graph/Chart) II-69

Table 21: World Historic Review for Other Apolipoprotein Tests
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America and Rest of World Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2003 through 2008 (includes corresponding
Graph/Chart) II-70

Table 22: World 15-Year Perspective for Other Apolipoprotein
Tests by Geographic Region - Percentage Breakdown of Unit
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan), Latin America, and Rest of World Markets for Years
2003, 2011 and 2017 (includes corresponding Graph/Chart) II-71


III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
In-Vitro Diagnostic Products Market: A Snapshot III-1
Cardiovascular Market: Startling Statistics III-1
Table 23: Prevalence of Cardiovascular Disease (CVD) in the
US: Population by Disease Type (in 000s) (includes
corresponding Graph/Chart) III-2
Cholesterol Testing - NCEP Recommendations Spurs Potential III-2
Trends and Issues III-3
Innovations Drive the Usage of Cardiovascular Monitoring
Systems III-3
Sterols and Stanols: Cholesterol-Lowering Products III-3
Cholesterol POCT Market: An Overview III-3
Table 24: US Cholesterol Point-of-Care Testing (2009):
Market Shares of Leading Players by Value Sales for
Inverness Medical, Polymer Technology Systems, and Roche
Diagnostics (includes corresponding Graph/Chart) III-4
Increasing Cardiovascular Ailments Drive Sales of Home Test
Devices III-4
Table 25: US Recent Past, Current and Future Analysis for
Home Cholesterol Monitoring Kits Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2009
through 2017 (includes corresponding Graph/Chart) III-4

Table 26: US Historic Review for Home Cholesterol
Monitoring Kits Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2003 through 2008
(includes corresponding Graph/Chart) III-5
B.Market Analytics III-6
Table 27: US Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-6

Table 28: US Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-7

Table 29: US 15-Year Perspective for Cholesterol and Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding
Graph/Chart) III-8

2. CANADA III-9
Market Analytics III-9
Table 30: Canadian Recent Past, Current and Future Analysis
for Cholesterol and Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding
Graph/Chart) III-9

Table 31: Canadian Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-10

Table 32: Canadian 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding
Graph/Chart) III-11

3. JAPAN III-12
Market Analytics III-12
Table 33: Japanese Recent Past, Current and Future Analysis
for Cholesterol and Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-12

Table 34: Japanese Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-13

Table 35: Japanese 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding
Graph/Chart) III-14

4. EUROPE III-15
A.Market Analysis III-15
Market Outlook III-15
Home Cholesterol Monitoring Kits Market in Western Europe III-15
Table 36: Western Europe Recent Past, Current and Future
Analysis for Home Cholesterol Monitoring Kits Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2009 through 2017 (includes corresponding Graph/Chart) III-15

Table 37: Western Europe Historic Review for Home
Cholesterol Monitoring Kits Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2003 through
2008 (includes corresponding Graph/Chart) III-16
B.Market Analytics III-17
Table 38: European Recent Past, Current and Future Analysis
for Cholesterol and Other Cardiovascular Testing by Geographic
Region - France, Germany, Italy, UK, Spain, Russia and Rest
of Europe Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2009 through 2017
(includes corresponding Graph/Chart) III-17

Table 39: European Historic Review for Cholesterol and Other
Cardiovascular Testing by Geographic Region - France,
Germany, Italy, UK, Spain, Russia and Rest of Europe Markets
Independently Analyzed with Annual Sales Figures in Million
Units for Years 2003 through 2008 (includes corresponding
Graph/Chart) III-18

Table 40: European 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Geographic Region -
Percentage Breakdown of Unit Sales for France, Germany,
Italy, UK, Spain, Russia and Rest of Europe Markets for
Years 2003, 2011 and 2017 (includes corresponding
Graph/Chart) III-19

Table 41: European Recent Past, Current and Future Analysis
for Cholesterol and Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/ Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-20

Table 42: European Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-21

Table 43: European 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding Graph/Chart) III-22

4a. FRANCE III-23
Market Analytics III-23
Table 44: French Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Product
Segment - Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-23

Table 45: French Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-24

Table 46: French 15-Year Perspective for Cholesterol and Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding Graph/Chart) III-25

4b. GERMANY III-26
Market Analytics III-26
Table 47: German Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/ Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding
Graph/Chart) III-26

Table 48: German Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-27

Table 49: German 15-Year Perspective for Cholesterol and Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding Graph/Chart) III-28

4c. ITALY III-29
Market Analytics III-29
Table 50: Italian Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-29

Table 51: Italian Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-30

Table 52: Italian 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding Graph/Chart) III-31

4d. THE UNITED KINGDOM III-32
Market Analytics III-32
Table 53: UK Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-32

Table 54: UK Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-33

Table 55: UK 15-Year Perspective for Cholesterol and Other
Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding
Graph/Chart) III-34

4e. SPAIN III-35
Market Analytics III-35
Table 56: Spanish Recent Past, Current and Future Analysis for
Cholesterol and Other Cardiovascular Testing by Product
Segment -Lipid Panel Test/Complete Lipid Profile, Total
Cholesterol Test, HDL Cholesterol Test, Apolipoprotein B,
and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding
Graph/Chart) III-35

Table 57: Spanish Historic Review for Cholesterol and Other
Cardiovascular Testing by Product Segment - Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets Independently Analyzed with Annual Sales
Figures in Million Units for Years 2003 through 2008
(includes corresponding Graph/Chart) III-36

Table 58: Spanish 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding
Graph/Chart) III-37

4f. REST OF EUROPE III-38
Market Analytics III-38
Table 59: Rest of Europe Recent Past, Current and Future
Analysis for Cholesterol and Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-38

Table 60: Rest of Europe Historic Review for Cholesterol and
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2003
through 2008 (includes corresponding Graph/Chart) III-39

Table 61: Rest of Europe 15-Year Perspective for Cholesterol
and Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for Years 2003, 2011 and 2017 (includes
corresponding Graph/Chart) III-40

5. ASIA-PACIFIC III-41
Market Analytics III-41
Table 62: Asia-Pacific Recent Past, Current and Future
Analysis for Cholesterol and Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-41

Table 63: Asia-Pacific Historic Review for Cholesterol and
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2003 through
2008 (includes corresponding Graph/Chart) III-42

Table 64: Asia-Pacific 15-Year Perspective for Cholesterol and
Other Cardiovascular Testing by Product Segment - Percentage
Breakdown of Unit Sales for Lipid Panel Test/Complete Lipid
Profile, Total Cholesterol Test, HDL Cholesterol Test,
Apolipoprotein B, and Other Apolipoprotein Tests Markets for
Years 2003, 2011 and 2017 (includes corresponding Graph/Chart) III-43

6. LATIN AMERICA III-44
Market Analytics III-44
Table 65: Latin American Recent Past, Current and Future
Analysis for Cholesterol and Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/ Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding Graph/Chart) III-44

Table 66: Latin American Historic Review for Cholesterol and
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2003 through
2008 (includes corresponding Graph/Chart) III-45

Table 67: Latin American 15-Year Perspective for Cholesterol
and Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for Years 2003, 2011 and 2017 (includes
corresponding Graph/Chart) III-46

7. REST OF WORLD III-47
Market Analytics III-47
Table 68: Rest of World Recent Past, Current and Future
Analysis for Cholesterol and Other Cardiovascular Testing by
Product Segment - Lipid Panel Test/Complete Lipid Profile,
Total Cholesterol Test, HDL Cholesterol Test, Apolipoprotein
B, and Other Apolipoprotein Tests Markets Independently
Analyzed with Annual Sales Figures in Million Units for
Years 2009 through 2017 (includes corresponding
Graph/Chart) III-47

Table 69: Rest of World Historic Review for Cholesterol and
Other Cardiovascular Testing by Product Segment - Lipid
Panel Test/Complete Lipid Profile, Total Cholesterol Test,
HDL Cholesterol Test, Apolipoprotein B, and Other
Apolipoprotein Tests Markets Independently Analyzed with
Annual Sales Figures in Million Units for Years 2003 through
2008 (includes corresponding Graph/Chart) III-48

Table 70: Rest of World 15-Year Perspective for Cholesterol
and Other Cardiovascular Testing by Product Segment -
Percentage Breakdown of Unit Sales for Lipid Panel
Test/Complete Lipid Profile, Total Cholesterol Test, HDL
Cholesterol Test, Apolipoprotein B, and Other Apolipoprotein
Tests Markets for Years 2003, 2011 and 2017 (include
corresponding Graph/Chart) III-49


IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 42 (including Divisions/Subsidiaries - 51)

------------------------------------------
Region/Country Players
------------------------------------------
The United States 34
Canada 1
Japan 4
Europe 9
Germany 1
The United Kingdom 4
Italy 1
Rest of Europe 3
Asia-Pacific (Excluding Japan) 3
------------------------------------------

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ref:plp2012

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