Sanofi Pasteur is the global market leader in aP based preschool booster vaccines, with Tetraxim® accounting for 34% of all doses administered.

A new report provides information on the usage patterns of aP (acellular pertussis) based preschool booster vaccines, the volumes administered by country and the leading brands. The study examines 88 countries which were using trivalent or tetravalent vaccines in their national immunisation schedule in 2019.

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The role for preschool booster vaccines.

Preschool booster vaccines are combination vaccines administered between the ages of 3 and 7 to protect children against two or more of the following diseases: diphtheria (D), tetanus (T), pertussis (aP) (Whooping cough), and poliomyelitis. They are important because the immunity conferred by vaccination during infancy wanes over time, and children are at greater risk of infection once they start school.

Based on the pertussis antigen component, preschool booster vaccines can be either DTaP (acellular pertussis) or DTwP (whole-cell pertussis). The vaccines come in three types: bivalent (DT, Td), trivalent (DTaP, DTwP, Tdap), or tetravalent (DTaP-IPV, Tdap-IPV).

aP based preschool booster vaccines consumed more in public markets.

The study found that aP based variants accounted for 14.5 million (41%) of the 35.5 million doses of preschool booster vaccine distributed globally. In 2019, 79% of aP based vaccines were consumed in public markets.

Public markets are those where the government finances and procures large quantities of vaccines through tenders. They are generally found in high and upper-middle income countries. In private markets, individuals pay for vaccines out of their own pockets or through personal insurance.

The largest public market was the United States of America (3.7 million doses), followed by Turkey (1.8 million doses) and the United Kingdom (783,000 doses). The largest private market was France (1 million doses).

Overall, more than half of the total volume of aP based preschool booster vaccine was administered in Europe.

aP based preschool booster vaccine volume analysis by region, 2019

On a global scale, Tetraxim® had the highest market share by volume.

Amongst the commercially available brands of aP based preschool booster vaccines, Tetraxim® (Sanofi Pasteur) had the highest market share by volume in 2019 with 34.1%. It was followed by Infanrix IPV® (GSK) with 24.3%; Boostrix® (GSK) with 15.3%; and Quadaracel® (Sanofi Pasteur) with 9%. Repevax® (Sanofi Pasteur), Boostrix-IPV® (GSK), and Adacel® (Sanofi Pasteur) all had shares of 7.2% or less.

In Europe, Tetraxim® was the dominant market leader with a 52.9% share by volume (3.9 million doses). Second was Boostrix® with 15.2%.

Market share of aP based preschool booster vaccines in top 40 European countries, 2019

Cumulatively, Sanofi Pasteur held the highest share of the global preschool booster vaccines market in 2019. Tetraxim®, Quadracel®, Adacel®, and Repevax® had a combined market share of 54% compared to 46% for GSK’s three brands (Infanrix-IPV®/Kinrix®, Boostrix-IPV®, and Boostrix®).

The report concludes that Tetraxim® is the most widely used aP based preschool booster vaccine, and Sanofi Pasteur is the global leader in the category.

 

Find out more about preschool booster vaccines.

A White Paper To Understand The Market Structure Of Acellular Pertussis Based Preschool Booster Combination Vaccines contains rich data on global volumes and utilisation trends for aP based trivalent and tetravalent booster vaccines.

To download your copy, click here.