EpiCast Report: Rheumatoid Arthritis - Epidemiology Forecast to 2025

EpiCast Report: Rheumatoid Arthritis - Epidemiology Forecast to 2025

Summary

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation of the joints, bone and cartilage erosion, and joint deformity. Additionally, the condition manifests itself in multiple joints in the body (CDC, 2015; Mayo Clinic, 2016). In RA, the body’s immune system attacks the lining of the joints, known as the synovial membrane, or synovium, causing an inflammatory response (CDC, 2015). The disease can lead to premature mortality, disability, and decreased quality of life.

In the 8MM, epidemiologists forecast that the diagnosed incident cases of RA will increase from 195,592 cases in 2015 to 216,467 cases in 2025, at an Annual Growth Rate (AGR) of 1.07%. The US will have the highest number of diagnosed incident cases of RA among the 8MM throughout the forecast period, while Spain will have the lowest.
Epidemiologists forecast that the diagnosed prevalent cases of RA will increase from 4,354,194 cases in 2015 to 4,931,572 cases in 2025, at an AGR of 1.33%. The US will have the highest number of diagnosed prevalent cases of RA among the 8MM throughout the forecast period, while Australia will have the lowest.

The report “EpiCast Report: Rheumatoid Arthritis - Epidemiology Forecast to 2025” provide an overview of the risk factors and global trends of RA in the eight major markets (8MM) (US, France, Germany, Italy, Spain, UK, Japan, and Australia). It includes a 10-year epidemiological forecast for the diagnosed incident cases, diagnosed prevalent cases, and total prevalent cases of RA segmented by age and sex in these eight markets. The diagnosed prevalent cases of RA are further segmented by severity in the 8 MM for the forecast period.

Scope

- The Rheumatoid Arthritis (RA) EpiCast Report provides an overview of the risk factors and global trends of RA in the eight major markets (8MM) (US, France, Germany, Italy, Spain, UK, Japan, and Australia). It includes a 10-year epidemiological forecast for the diagnosed incident cases, diagnosed prevalent cases, and total prevalent cases of RA segmented by age and sex in these eight markets. The diagnosed prevalent cases of RA are further segmented by severity in the 8 MM for the forecast period.
- The RA epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
- The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 8MM.

Reasons to buy

The RA EpiCast report will allow you to -
- Develop business strategies by understanding the trends shaping and driving the global RA market.
- Quantify patient populations in the global RA market to improve product design, pricing, and launch plans.
- Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for RA therapeutics in each of the markets covered.
- Identify the percentage of diagnosed prevalent cases of RA by severity.

1 Table of Contents
1 Table of Contents 5


2 Epidemiology 8
2.1 Disease Background 8
2.2 Risk Factors and Comorbidities 9
2.3 Global Trends 9
2.3.1 Diagnosed Incidence 11
2.3.2 Prevalence 12
2.4 Forecast Methodology 14
2.4.1 Sources Used 14
2.4.2 Forecast Assumptions and Methods 18
2.4.3 Sources Not Used 28
2.5 Epidemiological Forecast for RA (2015-2025) 28
2.5.1 Diagnosed Incident Cases 28
2.5.2 Diagnosed Prevalent Cases 35
2.5.3 Total Prevalent Cases 43
2.6 Discussion 50
2.6.1 Epidemiological Forecast Insight 50
2.6.2 Limitations of the Analysis 51
2.6.3 Strengths of the Analysis 52
3 Appendix 53
3.1 Bibliography 53
3.2 Physicians and Specialists Included in this Study 56
3.3 About the Authors 58
3.3.1 Epidemiologist 58
3.3.2 Reviewers 58
3.3.3 Global Director of Therapy Analysis and Epidemiology 59
3.4 About GlobalData 60
3.5 About EpiCast 60
3.6 Disclaimer 61

1.1 List of Tables
Table 1: Risk Factors and Comorbidities of RA 9
Table 2: 1987 ACR Diagnostic Criteria for RA 10
Table 3: 8MM, Sources Used to Forecast the Diagnosed Incident Cases of RA 15
Table 4: 8MM, Sources Used to Forecast the Total Prevalent Cases of RA 16
Table 5: 8MM, Sources Used to Forecast the Diagnosed Prevalent Cases of RA 17
Table 6: 8MM, Sources Used to Forecast Severity Segmentation of the Diagnosed Prevalent Cases of RA 18
Table 7: 8MM, Sources Not Used in the Epidemiological Analysis of RA 28
Table 8: 8MM, Diagnosed Incident Cases of RA, Ages ?18 Years, Both Sexes, N, Selected Years 2015-2025 29
Table 9: 8MM, Age-Specific Diagnosed Incident Cases of RA, Both Sexes, N (Row %), 2015 31
Table 10: 8MM, Sex-Specific Diagnosed Incident Cases of RA, Ages ?18 Years, N (Row %), 2015 33
Table 11: 8MM, Diagnosed Prevalent Cases of RA, Ages ?18 Years, Both Sexes, N, Selected Years 2015-2025 36
Table 12: 8MM, Age-Specific Diagnosed Prevalent Cases of RA, Both Sexes, N (Row %), 2015 38
Table 13: 8MM, Sex-Specific Diagnosed Prevalent Cases of RA, Ages ?18 Years, N (Row %), 2015 40
Table 14: 8MM, Total Prevalent Cases of RA, Ages ?18 Years, Both Sexes, N, Selected Years 2015-2025 44
Table 15: 8MM, Age-Specific Total Prevalent Cases of RA, Both Sexes, N (Row %), 2015 46
Table 16: 8MM, Sex-Specific Total Prevalent Cases of RA, Ages ?18 Years, N (Row %), 2015 48
Table 17: High-Prescribing Physicians (Non-KOLs), Surveyed by Country, 2016 57

1.2 List of Figures
Figure 1: 8MM, Diagnosed Incident Cases of RA, Ages ?18 Years, Both Sexes, N, 2015-2025 30
Figure 2: 8MM, Age-Specific Diagnosed Incident Cases of RA, Both Sexes, N, 2015 32
Figure 3: 8MM, Sex-Specific Diagnosed Incident Cases of RA, Ages ?18 Years, N, 2015 34
Figure 4: 8MM, Age-Standardized Diagnosed Incidence of RA, Ages ?18 Years, Cases per 100,000 Population, 2015 35
Figure 5: 8MM, Diagnosed Prevalent Cases of RA, Ages ?18 Years, Both Sexes, N, Selected Years 2015-2025 37
Figure 6: 8MM, Age-Specific Diagnosed Prevalent Cases of RA, Both Sexes, N, 2015 39
Figure 7: 8MM, Sex-Specific Diagnosed Prevalent Cases of RA, Ages ?18 Years, N, 2015 41
Figure 8: 8MM, Age-Standardized Diagnosed Prevalence of RA, Ages ?18 Years, %, 2015 42
Figure 9: 8MM, Diagnosed Prevalent Cases of RA by Severity, Both Sexes, Ages ?18 Years, N, 2015 43
Figure 10: 8MM, Total Prevalent Cases of RA, Ages ?18 Years, Both Sexes, N, Selected Years 2015-2025 45
Figure 11: 8MM, Age-Specific Total Prevalent Cases of RA, Both Sexes, N, 2015 47
Figure 12: 8MM, Sex-Specific Total Prevalent Cases of RA, Ages ?18 Years, N, 2015 49
Figure 13: 8MM, Age-Standardized Total Prevalence of RA, Ages ?18 Years, N, 2015 50