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Stem Cell Research Products – Opportunities, Tools, and Technologies – Market Size, Segments, Trends, and Projections to 2020

  • February 2016
  • 175 pages
  • BioInformant Worldwide, L.L.C.
Report ID: 3620225

Summary

Table of Contents

Whether you sell stem cell products or are an investor entering the marketplace, you need market intelligence in order to make smart, profitable decisions Stem cells are primitive cells found in all multi-cellular organisms that are characterized by self-renewal and the capacity to differentiate into mature cell types

Several broad categories of stem cells exist, including:

Embryonic stem cells, derived from blastocysts
Perinatal stem cells, obtained during the period immediately before and after birth
Adult stem cells, found in adult tissues
Induced pluripotent stem cells, produced by genetically reprogramming adults cells

Cancer stem cells, which give rise to clonal populations of cells that form tumors or disperse in the body

Stem cell research and experimentation have been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues In adult organisms, stem and progenitor cells act as a repair system for the body, replenishing specialized cells

Traditionally, scientists have worked with both embryonic and adult stem cells as research tools While the appeal of embryonic cells has been their ability to differentiate into any type of cell, there has been significant ethical, moral and spiritual controversy surrounding their use for research purposes Although some adult stem cells do have differentiation capacity, it is often limited in nature, which results in fewer options for use

Thus, when induced pluripotent stem cells (iPSCs) were produced from mouse cells in 2006 by Shinya Yamanaka of Kyoto University in Japan, they represented a promising combination of adult and embryonic stem cell characteristics By 2007, a series of follow-up experiments were done at Kyoto University in which human adult cells were transformed into iPSC cells Nearly simultaneously, a research group led by James Thomson at the University of Wisconsin-Madison accomplished the same feat of deriving iPSC lines from human somatic cells

The possibilities arising from stem cell characteristics have resulted in great commercial interest, with potential applications ranging from the use of stem cells in reversal and treatment of disease, to targeted cell therapy, tissue regeneration, pharmacological testing on cell-specific tissues, toxicology screening, and more

At this time, the following account for the majority of stem cell research:

Basic Research – Understanding stem cell mechanisms and behavior
Regenerative Medicine– Use of stem cells for the reversal of injury or disease
Drug Target Validation and Drug Delivery– Validation of the predicted target using living cells
Toxicology Screening– Use of stem cells to evaluate effects of drugs on biological systems

To facilitate research resulting from interest in these potential far-ranging applications, a large and growing stem cells research products market has emerged

Large companies selling stem cell research products include:

Thermo Fisher Scientific
BD Biosciences, a Division of Becton Dickinson
Merck KGaA
Miltenyi Biotec
STEMCELL Technologies
Lonza Group
Clontech (a Takara Bio Company)
GE Healthcare Life Sciences

While several of these dominant market players have utilized acquisition strategies to grow and capture market share, Merck KGaA has had a particularly strong commitment to this approach, acquiring several other massive major players within the stem cell research products marketplace, including Milllipore on February 26, 2010, for $72 billion, and Sigma-Aldrich on September 22, 2014, for $17 billion Dozens of mid-sized suppliers of stem cell research products also exist, as well as over 100 small specialty providers

Currently, the following compose the majority of stem cell research product sales worldwide:

Primary antibodies to stem cell antigens
Bead-based stem cell separation systems
Fluorescent-based labeling and detection
Stem cell protein purification and analysis tools
Tools for DNA and RNA-based characterization of stem cells
Isolation/characterization services
Stem cell culture media and reagents
Stem cell specific growth factors and cytokines
Tools for stem cell gene regulation
Stem cell services and mechanisms for in vivoand in vitro stem cell tracking
Expansion/differentiation services for stem cell media and RNAi
Stem cell lines

Key report findings include:

Market size determinations, with 5-year projections for the stem cell research products market (2016-2020)
Year-over-year analysis of stem cell grant rates, patent rates, clinical trial rates, and scientific publication rates
Stem cell funding sources, trends, and amounts (domestic and international)
Stem cell research applications, including priorities by segment
Relative demand for stem cell products, by stem cell type
Breakdown of stem cell product categories
Competitive analysis of leading stem cell research product companies
Online trends for stem cells, including Google Trends and Google Adwords
Social analytics for stem cells, including activity on Twitter, LinkedIn, Facebook, and more
Communications strategies for accessing the marketplace
End-user survey of stem cell scientists



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