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Pulmonary embolism - Pipeline Insight, 2021

Pulmonary embolism - Pipeline Insight, 2021

  • March 2021
  • 60 pages
  • ID: 5028220
  • Format: PDF
  • Delve Insight

Summary

Table of Contents

“Pulmonary embolism - Pipeline Insight, 2021,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Pulmonary embolism pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
• Global coverage

Pulmonary embolism Understanding

Pulmonary embolism: Overview
A pulmonary embolism is a blockage in the pulmonary artery, which supplies the blood to the lungs. Although pulmonary embolism can arise from anywhere in the body, most commonly it arises from the calf veins. It usually happens when a blood clot breaks loose and travels through the bloodstream to the lungs. Symptoms of a pulmonary embolism include sudden shortness of breath, pain in and around the chest and coughing. Pulmonary embolism is commonly detected through the following tests: Computed tomography (CT) scan, Lung scan, Blood tests (including the D-dimer test), Pulmonary angiogram, Ultrasound of the leg, Magnetic resonance imaging (MRI) of the legs or lungs. Medicines like anticoagulants, or blood thinners, keep blood clots from getting larger and stop new clots from forming; thrombolytics are medicines used to dissolve blood clots. A vena cava filter may be used in some people who cannot take blood thinners. Catheter-assisted thrombus removal procedure uses a flexible tube to reach a blood clot in your lung and a tool is inserted in the tube to break up the clot or to deliver medicine through the tube.
"Pulmonary embolism - Pipeline Insight, 2021" report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pulmonary embolism pipeline landscape is provided which includes the disease overview and Pulmonary embolism treatment guidelines. The assessment part of the report embraces, in depth Pulmonary embolism commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pulmonary embolism collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
• The companies and academics are working to assess challenges and seek opportunities that could influence Pulmonary embolism R&D. The therapies under development are focused on novel approaches to treat/improve Pulmonary embolism.

Pulmonary embolism Emerging Drugs Chapters
This segment of the Pulmonary embolism report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Pulmonary embolism Emerging Drugs
• Recombinant staphylokinase: Supergene
Recombinant staphylokinase contains Forteplase as the active substance. It is single chain molecule, consists of 138 amino acids. When staphylokinase is added to human plasma containing a fibrin clot, it preferentially reacts with plasmin at the clot surface, forming a plasmin-staphylokinase complex. The drug is in Phase III clinical evaluation for the treatment of pulmonary embolism.

• Reteplase: Angde Biotech Pharmaceutical
Reteplase is a recombinant human tissue-type plasminogen activator derivative. It is a non-glycosylated deletion mutein of tissue plasminogen activator (tPA), containing the kringle 2 and the protease domains of human tPA. The drug is in Phase II clinical developmental studies for the treatment of acute pulmonary embolism.
Further product details are provided in the report……..

Pulmonary embolism: Therapeutic Assessment
This segment of the report provides insights about the different Pulmonary embolism drugs segregated based on following parameters that define the scope of the report, such as:
• Major Players in Pulmonary embolism
There are approx. 5+ key companies which are developing the therapies for Pulmonary embolism. The companies which have their Pulmonary embolism drug candidates in the most advanced stage, i.e. Phase III include, Supergene.

• Phases
This report covers around 5+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Pulmonary embolism pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• Intravitreal
• Subretinal
• Topical

• Molecule Type
Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy

• Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Pulmonary embolism: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pulmonary embolism therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pulmonary embolism drugs.

Pulmonary embolism Report Insights
• Pulmonary embolism Pipeline Analysis

• Therapeutic Assessment
• Unmet Needs
• Impact of Drugs

Pulmonary embolism Report Assessment
• Pipeline Product Profiles

• Therapeutic Assessment
• Pipeline Assessment
• Inactive drugs assessment
• Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:
• How many companies are developing Pulmonary embolism drugs?
• How many Pulmonary embolism drugs are developed by each company?
• How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Pulmonary embolism?
• What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Pulmonary embolism therapeutics?
• What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Pulmonary embolism and their status?
• What are the key designations that have been granted to the emerging drugs?

Key Players
• Supergene
• Organicell Regenerative Medicine
• Angde Biotech Pharmaceutical
• Yuhan

Key Products
• Recombinant staphylokinase
• Zofin
• Reteplase
• YHP 1906

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