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Drug Overview: Zoladex

Drug Overview: Zoladex
  • Publish Date:January 2018

  • Number of Pages:8

  • Report ID:5391414

  • Format:PDF

  • Publisher:Datamonitor Healthcare

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Drug Overview
Zoladex (goserelin; AstraZeneca/TerSera Therapeutics) is a gonadotropin-releasing hormone (GnRH) receptor agonist which acts on the pituitary gland to stimulate luteinizing hormone (LH) release, resulting in a temporary surge in serum testosterone levels known as "flare." Persistent use of GnRH agonists over time causes downregulation of GnRH receptors in the pituitary gland, generating a significant reduction in LH and follicle-stimulating hormone secretion. This has the effect of complete shutdown of testosterone production in the testes, resulting in chemical castration.

Table of contents


4 Product Profiles
4 Zoladex : Prostate cancer

5 Figure 1: Zoladex sales for prostate cancer across the US, Japan, and five major EU...


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