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Hepatitis C: Drug Development Pipeline Study, H2 2018

Hepatitis C: Drug Development Pipeline Study, H2 2018

  • June 2018
  • 150 pages
  • ID: 5446604
  • Format: PDF
  • By VPAResearch

Summary

Table of Contents

With an estimated market value of over $30 billion by 2020, the Hepatitis C industry is considered as the rapidly growing healthcare markets. Hepatitis C affects around 200 million people worldwide and is associated with highest treatment failure rates. Currently, no vaccine is available against HCV. Due to the mutations in Hepatitis C virus, development of a prophylactic vaccine is highly challenging.

The condition is classified into 6 genotypes, of which GT-1 genotype is the most prevalent. The condition is a contagious liver disease which can be either acute or chronic. It can rapidly progress into serious liver problems including cirrhosis or liver cancer.

Hepatitis C pipeline comprises of 85 active drugs under active development as of June 2018. Of these, 16 drugs are in Phase 1 and 19 drugs in phase 2. Only 4 drugs progressed to Phase 3. Further, 27 drugs are in Pre-clinical stage, 18 drugs in research/discovery stages.

60 companies are developing the pipeline for Hepatitis C. Of this, GinkgoPharma Co. Ltd, Biocad CJSC, Cocrystal Pharma Inc, ARA Healthcare Pvt Ltd, GlaxoSmithKline Pharmaceuticals Ltd, Beijing Kawin Technology Share-Holding Co., Ltd. and Achillion Pharmaceuticals, Inc. have more compounds in pipeline. On the other hand, Presidio Pharmaceuticals, Inc, F. Hoffmann-La Roche Ltd, Ascletis, Inc. and Beijing Kawin Technology Share-Holding Co., Ltd. have most advanced pipeline products.

Mechanism of Action of most of the therapeutic candidates is HCV NS5A Inhibitors, Immunostimulants and Immunomodulators.

To assist researchers, investors and business development managers, VPA Research has come up with a comprehensive report on Hepatitis C (HCV) pipeline. The report provides insights into different therapeutic candidates in preclinical, research, discovery, NDA/IND, pre registration, phase 1, phase 2, and phase 3 trials). Drugs under development directly and through combination with other drugs are also included.

Current status, developmental phase, participating companies and entities, recent developments, orphan drug/ fast track/ other designations, drug class are provided for each Hepatitis C (HCV) pipeline product. Mechanism of Action and the target area of the pipeline product are also provided. Further, clinical and preclinical trials along with results of the trials are also included in the report.

In addition to complete details of each product, the report provides key trends in Hepatitis C (HCV) pipeline studies. The products under development are categorized according to their development phase, mechanism and company to provide detailed insights into the type of drugs being developed and the stages of development.

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