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Axial Spondyloarthritis (AxSpA): Competitive Landscape to 2026

Axial Spondyloarthritis (AxSpA): Competitive Landscape to 2026

  • June 2018
  • 52 pages
  • ID: 5473859
In this report:
PHASE II/III CLINICAL TRIALS HAD THE LOWEST ENROLLMENT EFFICIENCY (##.##%) DESPITE ENROLLING FEWER SUBJECTS THAN PHASE III CLINICAL TRIALS, WHERE HIGHER ENROLLMENT EFFICIENCIES WERE OBSERVED (##%).
Pfizer, the top industry sponsor in AxSpA, conducted a significant proportion of clinical trials, with the majority listed as completed (##%) and only ##% listed as active.

Summary

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Axial Spondyloarthritis : Competitive Landscape to 2026

Brief

Axial Spondyloarthritis is a chronic, immune-mediated inflammatory disease of the axial skeleton (sacroiliac joints and spine). It is characterized by a polyenthesitis, which at the molecular level leads to an osteitis and secondary synovitis.

In 2016, there were 1,458,896 diagnosed prevalent cases of AS across the 8MM, while there were over 800,000 diagnosed prevalent cases of nr-AxSpA. Epidemiologists forecast that the diagnosed prevalent cases of AS will cross 2,400,000 cases in 2026 across the 8MM, while nr-AxSpA will increase to over 1,350,000 cases.

Tumor necrosis factor is the most popular target for drug development for AxSpA, with 56 TNF inhibitors currently in the pipeline stage of development.As patents for traditional branded TNF inhibitors near their expiry, development of biosimilar drugs is growing, with 5 out of 17 drugs in Phases II and III being biosimilars.

The 5EU is the only market in which anti-TNF biologic products are approved for non-radiographic axial spondyloarthritis additionally to ankylosing spondylitis.However, UCB and Novartis are currently seeking label expansion to nr-AxSpA for Cimzia and Cosentyx globally. Overall, it is expected that additional drug approvals, including interleukin 17 inhibitors, will drive AxSpA market increase over the next decade (2016-2026).

Axial Spondyloarthritis : Competitive Landscape to 2026provides an assessment of the pipeline, clinical, and commercial landscape of AxSpA.

Overview

- GlobalData's Axial Spondyloarthritis : Competitive Landscape to 2026 combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a ambitious assessment of the disease marketplace.

Components of the slide deck contain -

- Pipeline Assessment: regional breakdown, favorable late-stage products, early-stage pipeline by molecule type

- Clinical Trials Assessment: trial breakdown by phase, leading industry and non-industry sponsors, enrollment analytics

- Commercial Assessment: leading marketed products, current and future players

- Competitive Landscape Analysis: top market events (2016-2026).

Great reasons to purchase

- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most strong pipeline.

- Develop strategic management by understanding the trends shaping and driving the overall AxSpA market.

- Drive revenues by understanding the main trends, innovative products and technologies, market segments, and firms likely to impact the overall AxSpA market in the outlook.

- Specified effective sales and marketing strategies by understanding the challenging landscape and by analyzing the performance of different competitors.

- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a ambitious advantage.

- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and tactical partnerships.

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