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Narcolepsy: Opportunity Analysis and Forecasts to 2027

Narcolepsy: Opportunity Analysis and Forecasts to 2027

  • June 2018
  • 103 pages
  • ID: 5500190
  • Format: PDF
  • GlobalData
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Narcolepsy: Opportunity Analysis and Forecasts to 2027

Drug sales for Narcolepsy in 2017 were approximately $1.39B across the seven major markets(US, France, Germany, Italy, Spain, UK, and Japan). Over the 10-year forecast period, the market is expected to grow to $3.7B at a CAGR of 10.4%. This growth will be driven by the launch of five late-stage pipeline products. The two highest selling drugs are expected to be Avadel’s/ Sodium oxybate ER and Jazz Pharmaceutical’s/JZP-258, which both address some of the unmet needs in the market.

Narcolepsy is a chronic sleep disorder characterized by two major symptoms, excessive daytime sleepiness (EDS) and cataplexy.There are two forms of narcolepsy recognized by The International Classification of Sleep Disorders: narcolepsy with cataplexy, also called narcolepsy type 1 (NT1); and narcolepsy without cataplexy, known as narcolepsy type 2 (NT2).

NT1 is most commonly caused by a deficiency of central nervous system (CNS) hypocretin (hcrt also called orexin) in the hypothalamus, while the cause for NT2 is still unknown and patients usually present normal levels of orexin.

There are currently few approved therapies available for narcolepsy; the majority of drugs are used off-label.Treatment needs to be tailored to the type of narcolepsy, NT1 or NT2.

Current treatments centre on the management of sleepiness and cataplexy symptoms, modafinils remaining the standard of care in the treatment of sleepiness while sodium oxybate for cataplexy symptoms. These therapies provide the best relief of symptoms, with Provigil (modafinil) and Xyrem (sodium oxybate) being the two most popular branded drugs.

The report "Narcolepsy: Opportunity Analysis and Forecasts to 2027", provides detailed insights into the market dynamics of this highly competitive space. This analysis also includes the evaluation of the commercial and clinical profiles of pipeline drugs, and their sales forecasts for the narcolepsy indication over the 2017-2027 periods.

The report specifically helps in answering -
- What are the key Narcolepsy treatments in 2017?
- When will the late stage pipeline products launch, and how will it affect drug sales and the overall Narcolepsy market in the 7MM?
- Which unmet needs will remain unaddressed in the forecast period and what opportunities remain for pharmaceutical companies?

Companies mentioned: Teva, Jazz Pharmaceuticals, Bioproject SCR, Avadel Pharmaceuticals, GSK, Pfizer, Theranexus, Flamel Ireland, NLS Pharma, Taisho Pharmaceutical, Balance Therapeutics.

- Overview of Narcolepsy, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and disease management.
- Annualized Narcolepsy therapeutics market revenue, cost of therapy per patient, and treatment usage patterns in two patient segments (Type 1 and Type 2) forecast from 2017 to 2027.
- Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping and implications for the Narcolepsy therapeutics market
- Pipeline analysis: comprehensive data assessing emerging trends and mechanisms of action under development for Narcolepsy therapy. The most promising candidates in Phase III development are profiled.
- Analysis of the current and future market competition in the global Narcolepsy therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy
The report will enable you to -
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
- Develop business strategies by understanding the trends shaping and driving the global Narcolepsy therapeutics market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global Narcolepsy therapeutics market in the future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

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