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Atopic Dermatitis Therapeutics in Southeast Asia Markets to 2024 - Growth Driven by Rising Awareness and Expected Launch of Novel Therapies

Atopic Dermatitis Therapeutics in Southeast Asia Markets to 2024 - Growth Driven by Rising Awareness and Expected Launch of Novel Therapies

  • November 2018
  • 113 pages
  • ID: 5664242
  • Format: PDF
  • By GlobalData

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Atopic Dermatitis Therapeutics in Southeast Asia Markets to 2024 - Growth Driven by Rising Awareness and Expected Launch of Novel Therapies

Summary
Atopic Dermatitis (AD), also called Atopic Eczema, is a chronic, pruritic, inflammatory skin disease associated with cutaneous hyper reactivity to environmental stimulants, with a wide range of severity. Patients typically experience periods of remission that are marked by acute inflammatory relapses known as ‘flares’. It is one of the most common skin diseases, affecting approximately 20% of children and 1-3% of adults in most countries. Atopic Dermatitis (AD) is slightly more common in males aged 6-7 and in females aged 13-14.

Atopic Dermatitis (AD) is a complex disease with a wide spectrum of symptoms affecting 15-20% of children and 1-3% of adults globally. Recent studies showed that its incidence has increased two to three fold in industrialized countries and its prevalence is increasing rapidly in low-income countries. The rising prevalence population, together with improving health awareness among the public and healthcare professionals, special healthcare programs, increasing health-insurance coverage, healthcare access and affordability will increase diagnosis and the treatment-receiving population, driving demand and contributing to market growth.

Southeast Asian Atopic Dermatitis (AD) market (South Korea, Singapore, Taiwan, Malaysia, the Philippines, Thailand, Vietnam, and Indonesia) is forecast to grow at a compound annual growth rate (CAGR) of 10.5% from 2017 to 2024.

The increase in uptake of recently approved and emerging targeted therapeutics, along with the continued uptake of existing branded therapies, will also propel market growth. Dupixent has the potential to be a game-changing therapy, as it is a first-in-class IL-drug and the first biologic approved for the treatment of Atopic Dermatitis (AD). In addition, Dupixent’s expected launch in Singapore and Taiwan will be the most important event in the Atopic Dermatitis (AD) market space in the near-term. The continued uptake of this novel targeted therapy will contribute to the increasing ACoT and in turn drive the market in South Korea, Singapore and Taiwan.

In recent years, targeted therapies have become a focus for Atopic Dermatitis (AD) treatment research. Biologics, small molecule and other therapies targeting specific immune pathways for Atopic Dermatitis (AD) are currently being studied in various phases along the drug development pipeline. The late-stage pipeline contains promising therapies that have the potential to achieve approval and launch over the forecast period.

On the other hand, novel topical therapies are still needed in the Atopic Dermatitis (AD) disease space, as current topical options are limited to corticosteroids and calcineurin inhibitors, which are associated with side effects, a long treatment duration, and low compliance. The launch of new pipeline therapies with better clinical profiles will significantly increase the treatment options for Atopic Dermatitis (AD) patients and improve care levels. Due to the positive impact expected to be made by therapies over the forecast period, the Atopic Dermatitis (AD) market is anticipated to undergo expansion in South East Asia.

Scope
- The Southeast Asia AD market will be valued at $848.6m in 2024, growing from $423.2m in2017, at a compound annual growth rate of 10.5%.
- What are the key factors driving the Southeast Asia AD treatment market?
- What classes of drugs dominate the market?
- How will the market respond to recent approval?
- How will novel IL-4Ra inhibitor therapy Dupixent, which holds first-to-market advantage, contribute to growth?
- The AD pipeline contains a range of molecule types and molecular targets, including those that are well established in AD and novel target therapies.
- Which classes of novel drugs are most prominent in the pipeline?
- What are the common targets and mechanisms of action of pipeline therapies?
- Late-stage pipeline therapies with a strong clinical record have the potential to enter the market over the forecast period.
- How have the late-stage therapies performed in clinical trials?
- What are the commercial prospects for the most promising late-stage products?
- How will the approval of tralokinumab, furestem-AD, baricitinib, PAC-14028 and PF-04965842, affect the competitive landscape?
- Various drivers and barriers will influence the market over the forecast period.
- Which factors are most likely to drive the market in these countries?
- What licensing and co-development deals have occurred within this therapy area since 2007?

Reasons to buy
This report will enable you to:
- Understand the current clinical and commercial landscape of AD by considering epidemiology, symptoms, etiology and pathophysiology, diagnosis, prognosis and treatment guidelines and options.
- Visualize the composition of the AD market in terms of the dominant therapies for each patient subset, along with their clinical and commercial standing. Unmet needs are highlighted to allow a competitive understanding of gaps in the market.
- Identify key pipeline trends in terms of molecule type, administration route, molecular target, and novelty.
- Consider market opportunities and potential risks by examining trends in AD clinical trial size, duration, and failure rate by stage of development, molecule type, and molecular target.
- Understand the potential of late-stage therapies with extensive profiles of products that could enter the market over the forecast period, highlighting clinical performance, potential commercial positioning, and how they will compete with other therapies.
- Predict AD market growth in the eight assessed Southeast Asian markets, with epidemiological and annual cost of therapy forecasts across South Korea, Singapore, Taiwan, Malaysia, the Philippines, Thailand, Vietnam, and Indonesia, as well as the individual contributions of promising late-stage molecules to market growth.
- Discover trends in licensing and co-development deals concerning AD products and identify the major strategic consolidations that have shaped the commercial landscape.

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