1. Market Research
  2. > Pharmaceutical
  3. > OTC Market Trends
Market Spotlight: Migraine, Pharma Intelligence

Market Spotlight: Migraine, Pharma Intelligence

  • October 2019
  • 73 pages
  • ID: 5780095
  • Format: PDF
  • By Pharma Intelligence

Summary

Table of Contents

This Market Spotlight report covers the migraine market, comprising key marketed and pipeline drugs, clinical trials, recent events and analyst opinion, upcoming and regulatory events, probability of success, patent information, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.

Key Takeaways
The analyst estimates that in 2017, there were 579.6 million prevalent cases of migraine in adults aged 20 years and older worldwide, and forecasts that number to increase to 649.2 million prevalent cases by 2026.
Latin America and the Caribbean is estimated to have the highest disease prevalence (16.4%), while Northern America has the lowest prevalence (9.7%).
The majority of approved drugs in the migraine space target the serotonin 5-HT1 receptor or GABA receptors. These are commonly administered via the oral route, with a smaller number of products being available in intravenous, intranasal, intramuscular, intradermal, intraarticular, intravesical, rectal, sublingual, oral transmucosal, and subcutaneous formulations.
The largest proportion of industry-sponsored drugs in active clinical development for migraine are in Phase III, with six drugs in the NDA/BLA phase.
Drugs in development for migraine focus on a wide variety of targets. Approximately half of the drugs in development for migraine are administered via the oral route, with the remainder being intranasal, inhaled, subcutaneous, intravenous, topical, transdermal, sublingual, oral transmucosal, and intramuscular formulations.
High-impact upcoming events for drugs in the migraine space comprise topline Phase II/III and Phase III trial results, an expected supplemental CHMP opinion, and FDA decisions on NDAs and BLAs.
The overall likelihood of approval of a Phase I migraine and other headaches asset is 15.7%, and the average probability a drug advances from Phase III is 93.8%. Drugs, on average, take 7.6 years from Phase I to approval, compared to 9.8 years in the overall neurology space.
There have been 29 licensing and asset acquisition deals involving migraine drugs during 2014–19. The largest deal was the $573.5m exclusive agreement between Bristol-Myers Squibb and Biohaven in 2016 to develop and commercialize rimegepant and BHV-3500, as well as for rights to other CGRP-related intellectual property.
The distribution of clinical trials across Phase I–IV indicates that the majority of trials for migraine have been in the early and mid-phases of development, with 55% of trials in Phase I–II, and 45% in Phase III–IV.
The US has a substantial lead in the number of migraine clinical trials globally. Germany leads the major EU markets, while Japan has the top spot in Asia.
Clinical trial activity in the migraine space is dominated by completed trials. GlaxoSmithKline has the highest number of completed clinical trials for migraine, with 95 trials.
GlaxoSmithKline leads the industry sponsors with by far the highest overall number of clinical trials for migraine, followed by Eli Lilly and Merck and Co.

Get Industry Insights. Simply.

  • Latest reports & slideshows with insights from top research analysts
  • 150+ Million searchable statistics with tables, figures & datasets
  • More than 25,000 trusted sources
  • Single User License — provides access to the report by one individual.
  • Department License — allows you to share the report with up to 5 users
  • Site License — allows the report to be shared amongst all employees in a defined country
  • Corporate License — allows for complete access, globally.
Ahmad helps you find the right report:
Testimonials

The research specialist advised us on the best content for our needs and provided a great report and follow-up, thanks very much we shall look at ReportLinker in the future.

Kate Merrick

Global Marketing Manager at
Eurotherm by Schneider Electric

We were impressed with the support that ReportLinker’s research specialists’ team provided. The report we purchased was useful and provided exactly what we want.

Category Manager at
Ikea

ReportLinker gave access to reliable and useful data while avoiding dispersing resources and spending too much time on unnecessary research.

Executive Director at
PwC Advisory

The customer service was fast, responsive, and 100% professional in all my dealings (...) If we have more research needs, I'll certainly prioritize working with ReportLinker!

Scott Griffith

Vice President Marketing at
Maurice Sporting Goods

The research specialist provided prompt, helpful instructions for accessing ReportLinker's product. He also followed up to make sure everything went smoothly and to ensure an easy transition to the next stage of my research

Jessica P Huffman

Research Associate at
American Transportation Research Institute

Excellent customer service. Very responsive and fast.

Director, Corporate Strategy at
Ingredion

I reached out to ReportLinker for a detailed market study on the Air Treatment industry. The quality of the report, the research specialist’s willingness to solve my queries exceeded my expectations. I would definitely recommend ReportLinker for in-depth industry information.

Mariana Mendoza

Global Platform Senior Manager at
Whirlpool Corporation

Thanks! I like what you've provided and will certainly come back if I need to do further research works.

Bee Hin Png

CEO at
LDR Pte Ltd

The research specialist advised us on the best content for our needs and provided a great report and follow-up, thanks very much we shall look at ReportLinker in the future.

Kate Merrick

Global Marketing Manager at
Eurotherm by Schneider Electric

FAQ
  • How we can help
    • I am not sure if the report I am interested in will fulfill my needs. Can you help me?
    • Yes, of course. You can call us at +33(0) 4 37 65 17 03 or drop us an email at researchadvisor@reportlinker.com to let us know more about your requirements.
    • We buy reports often - can ReportLinker get me any benefits?
    • Yes. Set up a call with a Senior Research Advisor to learn more - researchadvisor@reportlinker.com or +33(0) 4 37 65 17 03.
    • I have had negative experiences with market research reports before. How can you avoid this from happening again?
    • We advise all clients to read the TOC and Summary and list your questions so that we can get more insight for you before you make any purchase decision. A research advisor will accompany you so that you can compare samples and reports from different sources, and choose the study that is right for you.

  • Report Delivery
    • How and when I will receive my Report?
    • Most reports are delivered right away in a pdf format, while others are accessed via a secure link and access codes. Do note that sometimes reports are sent within a 12 hour period, depending on the time zones. However, you can contact us to escalate this. Should you need a hard copy, you can check if this option is offered for the particular report, and pay the related fees.
  • Payment conditions
    • What payment methods do you accept?
      1. Credit card : VISA, American Express, Mastercard, or
      2. You can download an invoice to pay by wire transfer, check, or via a Purchase Order from your company, or
      3. You can pay via a Check made out in US Dollars, Euros, or British Pounds for the full amount made payable to ReportLinker
    • What are ReportLinker’s Payment Terms?
    • All payments must normally be submitted within 30 days. However, you can let us know if you need extended time.
    • Are Taxes and duties included?
    • All companies based in France must pay a 20% tax per report. The same applies to all individuals based in the EU. All EU companies must supply their VAT number when purchasing to avoid this charge.
    • I’m not satisfied. Can I be refunded?
    • No. Once your order has been processed and the publisher has received a notification to send you the report, we cannot issue any refund or cancel any order. As these are not ‘traditional’ products that can be returned, reports that are dispatched are considered to be ‘consumed’.
  • User license
    • The license that you should acquire depends on the number of persons that need to access the report. This can range from Single User (only one person will have the right to read or access the report), or Department License (up to 5 persons), to Site License (a group of persons based in the same company location), or Corporate License (the entire company personnel based worldwide). However, as publishers have different terms and conditions, we can look into this for you.
Purchase Reports From Reputable Market Research Publishers
Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H2 2019

Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H2 2019

  • $ 3500
  • December 2019

Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H2 2019SummaryAccording to the recently published report ’Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H2 2019’; Calcitonin Gene ...

Calcitonin Gene Related Peptide Type 1 Receptor - Pipeline Review, H2 2019

Calcitonin Gene Related Peptide Type 1 Receptor - Pipeline Review, H2 2019

  • $ 3500
  • December 2019

Calcitonin Gene Related Peptide Type 1 Receptor - Pipeline Review, H2 2019SummaryCalcitonin Gene Related Peptide Type 1 Receptor (Calcitonin Receptor Like Receptor or CALCRL) - Calcitonin receptor-like ...

Nitric Oxide Synthase Brain - Pipeline Review, H2 2019

Nitric Oxide Synthase Brain - Pipeline Review, H2 2019

  • $ 3500
  • December 2019

Nitric Oxide Synthase Brain - Pipeline Review, H2 2019SummaryNitric Oxide Synthase Brain (Constitutive NOS or NC NOS or Neuronal NOS or bNOS or NOS Type I or Peptidyl Cysteine S Nitrosylase NOS1 or NOS1 ...


Download Unlimited Documents from Trusted Public Sources

Therapy Market in the US

  • January 2020
    49 pages
  • Therapy  

    Pain Relief  

  • United States  

View report >

OTC Industry Analysis - Forecast

  • October 2019
    13 pages
  • OTC  

    Antifungal  

  • United States  

    North America  

    Europe  

View report >

Global Pain Relief Forecast

  • October 2019
    4 pages
  • Pain Relief  

    Therapy  

  • World  

    United States  

View report >

Global OTC Markets 4 months ago

Pain Relief Supply 5 months ago

Global OTC Markets 6 months ago


ref:plp2019

Reportlinker.com © Copyright 2020. All rights reserved.

ReportLinker simplifies how Analysts and Decision Makers get industry data for their business.

Make sure you don’t miss any news and follow us on