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Antibody-drug Conjugates: Technology Growth Opportunities

Antibody-drug Conjugates: Technology Growth Opportunities

  • Publish Date:December 2022

  • Number of Pages:68

  • Report ID:6383510

  • Format:PDF

  • Publisher:Frost & Sullivan

$ 4950

Summary

Antibody-drug conjugates (ADCs) are therapies that target cancer cells with antigen-specific antibodies and highly toxic payloads.

ADCs are currently generating interest among drug developers, contract manufacturing companies, regulatory agencies, and other stakeholders.

The rise in the number of drug approvals has also sparked interest in further developing this technology, with several companies developing solutions for one or more ADC components.

The development of technologies is ongoing and will only increase as applications of ADCs increasingly expand into non-oncologic indications.This study covers several new technologies for the three ADC components (antibody, linker, and payload) and highlights drugs in clinical trials that display potential.

It provides an overview of key technology platforms, patents, analytical techniques, and manufacturing developments, covering the various technological advancements that may see adoption in ADC development.

It also provides an overview of the stakeholder ecosystem, identifying notable mergers, acquisitions, and partnerships.

A detailed account of the funding landscape has also been provided.

The study also analyzes the growth drivers and restraints influencing the market and identifies the key growth opportunities emerging from the changes in this space for stakeholders and market players to leverage.

Table of contents

Strategic Imperatives
Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
The Strategic Imperative 8™
The Impact of the Top 3 Strategic Imperatives on the Antibody-drug Conjugate (ADC) Industry
Growth Opportunities Fuel the Growth Pipeline Engine™
Research Methodology
Scope and Segmentation
Research Context and Scope
Segmentation
Growth Drivers
Growth Restraints
Growth Opportunity Analysis
Introduction to ADCs
Clinical Potential of ADCs
ADCs: FDA Approvals
ADC Industry Trends
Technology Snapshot
Incremental Innovations in ADCs
ADC Challenges and Novel Solutions

Characteristics of ADC Linkers
Types of Conventional ADC Linkers
Platforms for ADC Linkers

ADC Linker Developments
Platforms to Improve adc Conjugation

Characteristics of a Suitable Antibody for ADCs
Platforms for ADC Antibodies

Antibody Developments for ADC
Characteristics of a Suitable Cytotoxic Payload for an ADC
Platforms for Cytotoxic Payload for an ADC

Payload Developments for ADCs
Novel Platforms for ADC Delivery
Manufacturing, Analytical Techniques, and Other Factors
Impact on CDMOs
ADC: Analysis Technologies, Challenges, and New Developments
ADC: Clinical Pipeline
Stakeholder Ecosystem
M&As
Partnerships and Collaborations for ADCs

Technology Licensing Deals for ADC Development
Funding Landscape
Funding Analysis

Growth Opportunity Universe
Growth Opportunity 1: Non-oncological Indications

Growth Opportunity 2: Manufacturing and Supply Chain

Growth Opportunity 3: Advancements in Linker Chemistry and Antibodies

Next Steps
Your Next Steps
Why Frost, Why Now?
Legal Disclaimer

Methodology

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The data is gathered from a wide range of sources, including industry reports, government statistics, and company financials. This data is then analyzed and cross-referenced to ensure its accuracy and reliability. Next, primary interviews are conducted with industry experts and key stakeholders to gather their insights and perspectives on the market. This information is then combined with the data collected to provide a complete picture of the market. Macro-economic factor analysis is also carried out to understand the impact of external factors on the market. Finally, country-level data analysis is performed to understand the market dynamics in specific regions and countries.

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