Antibody-drug conjugates (ADCs) are therapies that target cancer cells with antigen-specific antibodies and highly toxic payloads.
ADCs are currently generating interest among drug developers, contract manufacturing companies, regulatory agencies, and other stakeholders.
The rise in the number of drug approvals has also sparked interest in further developing this technology, with several companies developing solutions for one or more ADC components.
The development of technologies is ongoing and will only increase as applications of ADCs increasingly expand into non-oncologic indications.This study covers several new technologies for the three ADC components (antibody, linker, and payload) and highlights drugs in clinical trials that display potential.
It provides an overview of key technology platforms, patents, analytical techniques, and manufacturing developments, covering the various technological advancements that may see adoption in ADC development.
It also provides an overview of the stakeholder ecosystem, identifying notable mergers, acquisitions, and partnerships.
A detailed account of the funding landscape has also been provided.
The study also analyzes the growth drivers and restraints influencing the market and identifies the key growth opportunities emerging from the changes in this space for stakeholders and market players to leverage.
Table of contents
Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
The Strategic Imperative 8™
The Impact of the Top 3 Strategic Imperatives on the Antibody-drug Conjugate (ADC) Industry
Growth Opportunities Fuel the Growth Pipeline Engine™
Scope and Segmentation
Research Context and Scope
Growth Opportunity Analysis
Introduction to ADCs
Clinical Potential of ADCs
ADCs: FDA Approvals
ADC Industry Trends
Incremental Innovations in ADCs
ADC Challenges and Novel Solutions
Characteristics of ADC Linkers
Types of Conventional ADC Linkers
Platforms for ADC Linkers
ADC Linker Developments
Platforms to Improve adc Conjugation
Characteristics of a Suitable Antibody for ADCs
Platforms for ADC Antibodies
Antibody Developments for ADC
Characteristics of a Suitable Cytotoxic Payload for an ADC
Platforms for Cytotoxic Payload for an ADC
Payload Developments for ADCs
Novel Platforms for ADC Delivery
Manufacturing, Analytical Techniques, and Other Factors
Impact on CDMOs
ADC: Analysis Technologies, Challenges, and New Developments
ADC: Clinical Pipeline
Partnerships and Collaborations for ADCs
Technology Licensing Deals for ADC Development
Growth Opportunity Universe
Growth Opportunity 1: Non-oncological Indications
Growth Opportunity 2: Manufacturing and Supply Chain
Growth Opportunity 3: Advancements in Linker Chemistry and Antibodies
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