2 Table of Contents

1 About the Authors 2
1.1 Analysts 2
1.1.1 Linda Tian, MSc, Managing Analyst, Medical Devices 2
1.2 Global Head of Medical Devices 2
1.2.1 Tyler Fletcher, Global Head of Medical Devices 2

2 Table of Contents 3
2.1 List of Tables 4
2.2 List of Figures 5

3 Introduction 6
3.1 Overview 6
3.2 Related Reports 6

4 Unmet Needs and Market Opportunity Analysis 7
4.1 Lack of Definitive Methods to Determine Fusion Performance 7
4.2 Technological Developments in the Use of Long Fusions 7
4.3 Research and Development into Fusion Enhancers 7
4.4 Develop Signature Minimally Invasive Technique 9
4.5 Develop a Device that Provides Real-Time Fusion Updates 10

5 Market Drivers and Barriers 11
5.1 Driver: Gold Standard for Treating Spinal Instability and Degenerative Conditions 11
5.2 Driver: Growth in the Spinal Stenosis Indication 11
5.3 Driver: Expandable Spinal Implants 12
5.4 Driver: Treatment for a Variety of Indications 13
5.5 Driver: Advances in Navigation Technology 13
5.6 Barrier: Incidence of Adjacent Segment Disease 14
5.7 Barrier: Performance in Treating Axial Back Pain 15

6 Company Market Share 16
6.1.1 Middle East and Africa 16
6.2 Company Profiles 16
6.2.1 Aesculap 16
6.2.2 Alphatec Spine 17
6.2.3 Amedica Corporation 18
6.2.4 DePuy Synthes 19
6.2.5 Globus Medical 20
6.2.6 K2M 22
6.2.7 Medtronic 23
6.2.8 NuVasive 24
6.2.9 Orthofix 26
6.2.10 SeaSpine 27
6.2.11 Stryker 28
6.2.12 Zimmer Biomet 30
6.3 Pipeline Assessment 32
6.4 Mergers & Acquisitions 33

7 Market Outlook 34
7.1 Procedure Trends 34
7.1.1 Middle East and Africa 34
7.2 By Geography 35
7.2.1 Middle East and Africa 35

8 Appendix 38
8.1 Bibliography 38
8.2 Abbreviations 40
8.3 Methodology 41
8.3.1 Overview 41
8.3.2 Coverage 41
8.3.3 Secondary Research 41
8.4 Forecasting Methodology 42
8.5 Primary Research Summary 43
8.5.1 Primary Research - Key Opinion Leader Interviews 43
8.5.2 Expert Panel Validation 43
8.6 About MediPoint 43
8.7 About GlobalData 44
8.8 Contact Us 44
8.9 Disclaimer 44

2.1 List of Tables
Table 1: Product Portfolio - Aesculap 17
Table 2: Product Portfolio - Alphatec Spine 18
Table 3: Product Portfolio - Amedica 19
Table 4: Product Portfolio - DePuy Synthes 20
Table 5: Product Portfolio - Globus Medical 21
Table 6: Product Portfolio - K2M 23
Table 7: Product Portfolio - Medtronic 24
Table 8: Product Portfolio - NuVasive 25
Table 9: Product Portfolio - Orthofix 27
Table 10: Product Portfolio - SeaSpine 28
Table 11: Product Portfolio - Stryker 29
Table 12: Product Portfolio - Zimmer Biomet 30
Table 13: Pipeline Assessment, 2016 32
Table 14: Key Mergers, Acquisitions, and Partnerships in Spinal Fusion Market (2015-2016) 33
Table 15: Middle East and Africa Spinal Fusion Sales ($m) Forecast, 2014-2023 35
Table 16: Middle East and Africa Spinal Fusion Sales ($m) Forecast, by Geography, 2014-2023 36

2.2 List of Figures
Figure 1: Middle East and Africa Spinal Fusion Market Share, 2016 16
Figure 2: Middle East and Africa Spinal Fusion Procedure Volumes, by Anatomy, 2014-2023 34
Figure 3: Middle East and Africa Spinal Fusion Procedure Volumes, by Geography, 2014-2023 35
Figure 4: Middle East and Africa Spinal Fusion Sales ($m) Forecast, 2014-2023 36
Figure 5: Middle East and Africa Spinal Fusion Market Revenue Distribution, 2016 37

Companies Mentioned
- Aesculap
- Alphatec Spine
- Amedica Corporation
- DePuy Synthes
- Globus Medical
- K2M
- Medtronic
- NuVasive
- Orthofix
- SeaSpine
- Stryker
- Zimmer Biomet