1 Table of Contents 2
1.1 List of Tables 4
1.2 List of Figures 7

2 Key Highlights 8
2.1 Osteosarcoma- Introduction 8
2.1.1 United States, France and Germany Dominate the Global Clinical Trials 9
2.1.2 Around 13% of trials are directly sponsored by Companies 10
2.1.3 10% trials conducted in Emerging Economies 10

3 Evolution of Osteosarcoma Clinical Trials to 2017 11
3.1 Emergence of Clinical Trials Count by Year 11
3.2 Trials Moving into Late Phases 14
3.2.1 Trials by Phase, 2002- 2017 14
3.3 Trials by Recruitment Status 16
3.4 16% of Trials are Observational in Type 17

4 Geographical Analysis of Osteosarcoma Clinical Trial 18
4.1 Region wise Trials Count 18
4.2 Top 10 Countries- Clinical Trials 19
4.3 Emerging and Developing Markets- Clinical Trials 20
4.3.1 Trials in Emerging and Developing Economies, 2002- 2017 21
4.4 Advanced Economies- Clinical Trials 22
4.5 Europe - Leading Countries 23
4.6 North America - Leading Countries 24
4.7 South and Central America- Leading Countries 25
4.8 Western Pacific - Leading Countries 26

5 Enrolment Trends in Osteosarcoma Clinical Trials 27
5.1 Subjects Recruited by year 27
5.2 Subjects Recruited by Phase 28
5.3 Subjects Recruited by Trial Type 29
5.4 Subjects Recruited by Recruitment Status 30

6 Key Sponsors and Drugs Intervened in Osteosarcoma Clinical Trials 31
6.1 Clinical Trials Count by Sponsor Type 31
6.2 Subjects Recruited by Sponsor Type 32
6.3 Subjects Recruited by Leading Sponsors 33

7 Recent Clinical Trials- Snapshots 34
7.1 Osteosarcoma Recent Clinical Trials- Phase 1 34
7.2 Osteosarcoma Recent Clinical Trials- Phase 2 46
7.3 Osteosarcoma Recent Clinical Trials- Phase 3 111
7.4 Osteosarcoma Recent Clinical Trials- Phase 4 115

8 Appendix 118
8.1 Abbreviations and Definitions 118
8.2 Contact Information 119
8.3 Sources and Research Methodology 119
8.4 Copyright and Disclaimer 120

1.1 List of Tables
Table 1: Osteosarcoma- Clinical Trials by Sponsor Type, 2017 10
Table 2: Osteosarcoma- Clinical Trials by Economy Type, 2017 10
Table 3: Osteosarcoma- Clinical Trials by Region, 2000-2017 18
Table 4: Osteosarcoma- Clinical Trials in Top 10 Countries, 2017 19
Table 5: Osteosarcoma- Clinical Trials in Emerging and Developing Economies, 2017 21
Table 6: Osteosarcoma- Clinical Trials in Advanced Nations, 2017 22
Table 7: Osteosarcoma- Phase 1 Trial Snapshots 34
Table 8: Osteosarcoma- Phase 1 Trial Snapshots 35
Table 9: Osteosarcoma- Phase 1 Trial Snapshots 35
Table 10: Osteosarcoma- Phase 1 Trial Snapshots 36
Table 11: Osteosarcoma- Phase 1 Trial Snapshots 36
Table 12: Osteosarcoma- Phase 1 Trial Snapshots 37
Table 13: Osteosarcoma- Phase 1 Trial Snapshots 37
Table 14: Osteosarcoma- Phase 1 Trial Snapshots 38
Table 15: Osteosarcoma- Phase 1 Trial Snapshots 38
Table 16: Osteosarcoma- Phase 1 Trial Snapshots 39
Table 17: Osteosarcoma- Phase 1 Trial Snapshots 39
Table 18: Osteosarcoma- Phase 1 Trial Snapshots 40
Table 19: Osteosarcoma- Phase 1 Trial Snapshots 40
Table 20: Osteosarcoma- Phase 1 Trial Snapshots 41
Table 21: Osteosarcoma- Phase 1 Trial Snapshots 41
Table 22: Osteosarcoma- Phase 1 Trial Snapshots 42
Table 23: Osteosarcoma- Phase 1 Trial Snapshots 42
Table 24: Osteosarcoma- Phase 1 Trial Snapshots 43
Table 25: Osteosarcoma- Phase 1 Trial Snapshots 43
Table 26: Osteosarcoma- Phase 1 Trial Snapshots 44
Table 27: Osteosarcoma- Phase 1 Trial Snapshots 44
Table 28: Osteosarcoma- Phase 1 Trial Snapshots 45
Table 29: Osteosarcoma- Phase 2 Trial Snapshots 46
Table 30: Osteosarcoma- Phase 2 Trial Snapshots 47
Table 31: Osteosarcoma- Phase 2 Trial Snapshots 48
Table 32: Osteosarcoma- Phase 2 Trial Snapshots 49
Table 33: Osteosarcoma- Phase 2 Trial Snapshots 50
Table 34: Osteosarcoma- Phase 2 Trial Snapshots 51
Table 35: Osteosarcoma- Phase 2 Trial Snapshots 52
Table 36: Osteosarcoma- Phase 2 Trial Snapshots 53
Table 37: Osteosarcoma- Phase 2 Trial Snapshots 54
Table 38: Osteosarcoma- Phase 2 Trial Snapshots 55
Table 39: Osteosarcoma- Phase 2 Trial Snapshots 56
Table 40: Osteosarcoma- Phase 2 Trial Snapshots 57
Table 41: Osteosarcoma- Phase 2 Trial Snapshots 58
Table 42: Osteosarcoma- Phase 2 Trial Snapshots 59
Table 43: Osteosarcoma- Phase 2 Trial Snapshots 60
Table 44: Osteosarcoma- Phase 2 Trial Snapshots 61
Table 45: Osteosarcoma- Phase 2 Trial Snapshots 62
Table 46: Osteosarcoma- Phase 2 Trial Snapshots 63
Table 47: Osteosarcoma- Phase 2 Trial Snapshots 64
Table 48: Osteosarcoma- Phase 2 Trial Snapshots 65
Table 49: Osteosarcoma- Phase 2 Trial Snapshots 66
Table 50: Osteosarcoma- Phase 2 Trial Snapshots 67
Table 51: Osteosarcoma- Phase 2 Trial Snapshots 68
Table 52: Osteosarcoma- Phase 2 Trial Snapshots 69
Table 53: Osteosarcoma- Phase 2 Trial Snapshots 70
Table 54: Osteosarcoma- Phase 2 Trial Snapshots 71
Table 55: Osteosarcoma- Phase 2 Trial Snapshots 72
Table 56: Osteosarcoma- Phase 2 Trial Snapshots 73
Table 57: Osteosarcoma- Phase 2 Trial Snapshots 74
Table 58: Osteosarcoma- Phase 2 Trial Snapshots 75
Table 59: Osteosarcoma- Phase 2 Trial Snapshots 76
Table 60: Osteosarcoma- Phase 2 Trial Snapshots 77
Table 61: Osteosarcoma- Phase 2 Trial Snapshots 78
Table 62: Osteosarcoma- Phase 2 Trial Snapshots 79
Table 63: Osteosarcoma- Phase 2 Trial Snapshots 80
Table 64: Osteosarcoma- Phase 2 Trial Snapshots 81
Table 65: Osteosarcoma- Phase 2 Trial Snapshots 82
Table 66: Osteosarcoma- Phase 2 Trial Snapshots 83
Table 67: Osteosarcoma- Phase 2 Trial Snapshots 84
Table 68: Osteosarcoma- Phase 2 Trial Snapshots 85
Table 69: Osteosarcoma- Phase 2 Trial Snapshots 86
Table 70: Osteosarcoma- Phase 2 Trial Snapshots 87
Table 71: Osteosarcoma- Phase 2 Trial Snapshots 88
Table 72: Osteosarcoma- Phase 2 Trial Snapshots 89
Table 73: Osteosarcoma- Phase 2 Trial Snapshots 90
Table 74: Osteosarcoma- Phase 2 Trial Snapshots 91
Table 75: Osteosarcoma- Phase 2 Trial Snapshots 92
Table 76: Osteosarcoma- Phase 2 Trial Snapshots 93
Table 77: Osteosarcoma- Phase 2 Trial Snapshots 94
Table 78: Osteosarcoma- Phase 2 Trial Snapshots 95
Table 79: Osteosarcoma- Phase 2 Trial Snapshots 96
Table 80: Osteosarcoma- Phase 2 Trial Snapshots 97
Table 81: Osteosarcoma- Phase 2 Trial Snapshots 98
Table 82: Osteosarcoma- Phase 2 Trial Snapshots 99
Table 83: Osteosarcoma- Phase 2 Trial Snapshots 100
Table 84: Osteosarcoma- Phase 2 Trial Snapshots 101
Table 85: Osteosarcoma- Phase 2 Trial Snapshots 102
Table 86: Osteosarcoma- Phase 2 Trial Snapshots 103
Table 87: Osteosarcoma- Phase 2 Trial Snapshots 104
Table 88: Osteosarcoma- Phase 2 Trial Snapshots 105
Table 89: Osteosarcoma- Phase 2 Trial Snapshots 106
Table 90: Osteosarcoma- Phase 2 Trial Snapshots 107
Table 91: Osteosarcoma- Phase 2 Trial Snapshots 108
Table 92: Osteosarcoma- Phase 2 Trial Snapshots 109
Table 93: Osteosarcoma- Phase 2 Trial Snapshots 110
Table 94: Osteosarcoma- Phase 3 Trial Snapshots 111
Table 95: Osteosarcoma- Phase 3 Trial Snapshots 112
Table 96: Osteosarcoma- Phase 3 Trial Snapshots 112
Table 97: Osteosarcoma- Phase 3 Trial Snapshots 113
Table 98: Osteosarcoma- Phase 3 Trial Snapshots 114
Table 99: Osteosarcoma- Phase 3 Trial Snapshots 114
Table 100: Osteosarcoma- Phase 4 Trial Snapshots 115
Table 101: Osteosarcoma- Phase 4 Trial Snapshots 116
Table 102: Osteosarcoma- Phase 4 Trial Snapshots 117

1.2 List of Figures
Figure 1: Osteosarcoma- Clinical Trials by Country, 2000- 2017 9
Figure 2: Osteosarcoma- Clinical Trials by Year, 2002- 2017 11
Figure 3: Osteosarcoma- Clinical Trials by Phase of Development, 2017 14
Figure 4: Osteosarcoma- Clinical Trials by Status, 2017 16
Figure 5: Osteosarcoma- Clinical Trials by Type, 2017 17
Figure 6: Osteosarcoma- Clinical Trials Split by Region, 2000-2017 18
Figure 7: Osteosarcoma- Clinical Trials by Type of Economy, 2017 20
Figure 8: Osteosarcoma- Clinical Trials in Europe, 2017 23
Figure 9: Osteosarcoma- Clinical Trials in North American Countries, 2017 24
Figure 10: Osteosarcoma- Clinical Trials in South and Central American Countries, 2017 25
Figure 11: Osteosarcoma- Clinical Trials in Western Pacific Countries, 2017 26
Figure 12: Osteosarcoma- Enrolment Numbers by Year, 2002- 2017 27
Figure 13: Osteosarcoma- Enrolment by Phase, 2017 28
Figure 14: Osteosarcoma- Enrolment by Trial Type, 2017 29
Figure 15: Osteosarcoma- Enrolment by Recruitment Status, 2017 30
Figure 16: Osteosarcoma- Clinical Trials by Sponsor Type, 2017 31
Figure 17: Osteosarcoma- Enrolment by Type of Sponsors 32
Figure 18: Osteosarcoma- Enrolment by Leading Sponsors 33

Companies Mentioned
Merck Sharp & Dohme Corp., Insmed Incorporated, Oncolytics Biotech, Eli Lilly and Company, Pfizer, Epeius Biotechnologies, Millennium Pharmaceuticals, Inc., BTG International Inc., Hoffmann-La Roche, Novartis Pharmaceuticals and 14 others