In 2023, the US recorded a baseline of 18.4 deaths per hundred thousand persons due to chronic liver diseases and cirrhosis. Forecast data indicates a rising trend from 2024 to 2028, increasing from 19.2 to 22.4 deaths per hundred thousand. Year-on-year, this reflects a consistent increase: 4.7% in 2025, 4.0% in 2026, 3.8% in 2027, and 3.2% in 2028. The 5-year compound annual growth rate (CAGR) is projected at approximately 4.0%.
Future trends to watch for include the impact of lifestyle changes, policy interventions, advancements in medical treatment, and public awareness campaigns on liver health. Tracking these factors will be essential for understanding mortality trends in the coming years.
